Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Eucommia ulmoides
Species name
Eucommia ulmoides is a species of eudicot in the family Eucommiaceae.
Species info
Gene sequence info
Eucommia_ulmoides.4CL.fa
Download
>EUC19307-RA
MEKSGYGRDGIYRSLRPPLVLPRDPNFSMISFLFRNSSSYPDKPALVDAVSGETLTFSQFKSAVAKASHGLFRLGIKKSDVVLIFAPNSIQFPICFCGIIAIGAIATTVNPIYTVSELSKQIKDCSPKLVITVSELLDKFKGFDLPALILGSDKSFMDLNTSSRITLFSDLINNSGSISNFPNVSINQTDTAALLYSSGTTGISKGVILTHRNFIAASLMVTADQELAGEMHNSFLCVLPMFHVFGLAVIMYAQLQRGNAIVSLAKFDFGIILKSVEKYRITHLWVVPPIILALAKQSVVKKYDLSSLKLIGSGAAPLGKELMEECAKNFPQAVVYQGYGMTETCGIVSLENPYGGIRHSGSAGTLVPGVESQIVSVDTLKPMPPNQLGEIWVRGPNMMQGYFNNPQATKLTIDKQGWVHTGDLGYFDEAGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVCSPNSSLTEEDVQNFIAKQVAPFKRIRRVTFTNTVPKSASGKILRRELIEKVRSQSKLTKTAATILWLFFSLFIRQLMVVIKAFEALQSLHCRFGRNFGGFGSTTPSSLLQLKFESFVSSKVGIH
>EUC07939-RA
MLMITNPFFTPAEIVKPVKASDAKLMVTPAYHVDKVRDFTNKNDMRIICIDSFPDSCLYFSKLTRVGDKVKCPTIEI
>EUC15175-RA
MAAKDKKQEFIFRSILPEIDIPSHLPLYLYCFQNKSRIKSRTCLIDESTGNTFTYADVELNAKKVAAGLLNLGGIGQGDVIMLLLSNLPEFAFALLGISYLGAISTTVNPCFSADEIFKQVESSRPKLIITEACYVEKVRKFAGIRVICTDSSPAGCLNFSDLKGDEIPATKIKSDDVAVIPYTSGTTGFPKGVMLTHKGLITNIAQQVDGENPNINITTNDVLICVLPMYHMYSMNCVLLCGIRAGATIVIMKKFEINKMLEVIQKYRVTIAHLVPPIVLSIDKSPVVGAAPLGKELERAVRAKLPNAKLGQGHGMTEGGPVISLSLSFAKEPVEMKSGSSGVVLRNAEMKIVDPNTGISLPPNQPGEVCVRGDNVMKGYLYDPEVPTTKMDNGWLQTGDFGYVDDDQELFIIERFKELIKYKEFQVAPAELEAILISHPNISDVAVVPLQDEAVGEVPVAFVVRATGSIITEDQVKQFVSEKVEVYKRINRVIFIDSIPKVASGKILRKELSGRLK
>EUC13566-RA
MDESTGDTFTYADVELNARKVAAGLLNLGGIGQDDVIMLLLSNLSEFAFALLDISYLGAISTIVNPCFKAKEIFKQVESSRSKFIISEACYVEKIRKFARIKVICTDSLPAGCLNFSDLKGDEISATKIKPVDVTVVL
>EUC13567-RA
MNLCFSAEEIFKQVESSRPKLIITEACYVEKVRKFAGIKVICTDSSPAGCSNFSNLKGGKISATKINPDDVAVTPYTSRTTGFPKRVMLTHKGLITNIAQQVDNKNPNINITTDGVLICILPMYHMYSMNCVLFVWDPGRSDDCDHEEV
>EUC11437-RA
MTMLSTVETPPQKPEPSSPVVPSILAPPQSHIFTSKLPPIPIPNHLPLHTYCFQDLSHDDNRTCLIAGARTFSFAQTHLLCRKVASGLSKQGIRKGDVIMVLLQNCPEFVFSFMGASILGAATTTANPFYTTAEIFKQFQASEAKLIITQSQYVDKLRDPGEDYPKLGEDFTVITVDDPPEKCLHFSVLSEEADELESSKVSIDPNDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGDNPNLHLTTEDVVLCVLPLFHIFSLNSVLMCALRAGAAVLLMPKFEIGALLEQIQRHRVSVAAVVPPLVLALAKNPMVDSFDLSSIRAVLSGAAPLGKELENALRTRLPQAIFGQVKKKREDLPTRIRNTNICHQFLTFSVXXXXXXAFAKQPFPTKSGSCGTVVRNAELKVVDPDNGSSLPHNQPGEICIRGPQIMKGYLNDEEATARTIDVDGWLHTGDIGYVDDDDEVFIVDRVKELIKFKGFQVPPAELEALLVSHSSIADAAVVPQKDEGAGEVPVAFVVPSEGADLTEEAVKEFIAKQVVFYKKLHKVYFVDSIPKSPSGKILRKDLRSKLPLPSSSLS
>EUC18014-RA
MEFKSEQKDIIFRSKLPDIDIPKHLSLHSYCFEKISEFGSRPCLINGATDEVYSYADVERISRQFAAGLNRNGVSKGETIMILLPNSPEFVFAFLGASFRGAVSTMANPLFTPAEVVKQAKAAGVKLIVTQACHVGKVRDFANENDVRIACIDSPPDGCLHFSELTRPGDEDECPAVEIQPDDVVCLPYSSGTTGLPKGVMLTHKGQVTSVAQQVDGENPNLYMHSDDVLLCVLPLFHVYSLNSILFCGLRVGAAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLMAIAKSPVVDKYDLSSIRTVMSGAAPLGKELEDTVRAKIPNAKLGQGYGMTEAGQSRSR
>EUC23429-RA
MAAIEEHVFRSRYGSVPVPENVLLPDFVLQDVELYADKVAFVDALTGKGYTYGEVSRDVRRFSKALKSLGLRKGRVVVVALPNVAEYPIVALGVMAAGGVFSGTNPAAHASEIKKQVEAADAKLIVTDATTYNKVKSLELPVIVLGDEAVEGTICWNELLEAGDRAGTDTINEVVLQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVGPELVGQVTTLGLIPFFHIYGLAGICCATLRNKGKVVVMGRYELRAFLNALIEHEVTFAPIVPPIILGLVKNPIVDEFDLGRLKLRSIMTAAAPLAPEILSEFEKKFPGVDVQEAYGMTEHSCITLTHGDPSKGQDISKKHSVGFILPNLEVKFIDPDTGLSLPMNTPGEICVRSQCVMLGYYNNEKETAHTIDQNGWLHTGDIGYIDDDGDIFLVDRIKELIKFKGFQ
MEKSGYGRDGIYRSLRPPLVLPRDPNFSMISFLFRNSSSYPDKPALVDAVSGETLTFSQFKSAVAKASHGLFRLGIKKSDVVLIFAPNSIQFPICFCGIIAIGAIATTVNPIYTVSELSKQIKDCSPKLVITVSELLDKFKGFDLPALILGSDKSFMDLNTSSRITLFSDLINNSGSISNFPNVSINQTDTAALLYSSGTTGISKGVILTHRNFIAASLMVTADQELAGEMHNSFLCVLPMFHVFGLAVIMYAQLQRGNAIVSLAKFDFGIILKSVEKYRITHLWVVPPIILALAKQSVVKKYDLSSLKLIGSGAAPLGKELMEECAKNFPQAVVYQGYGMTETCGIVSLENPYGGIRHSGSAGTLVPGVESQIVSVDTLKPMPPNQLGEIWVRGPNMMQGYFNNPQATKLTIDKQGWVHTGDLGYFDEAGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPIAYVVCSPNSSLTEEDVQNFIAKQVAPFKRIRRVTFTNTVPKSASGKILRRELIEKVRSQSKLTKTAATILWLFFSLFIRQLMVVIKAFEALQSLHCRFGRNFGGFGSTTPSSLLQLKFESFVSSKVGIH
>EUC07939-RA
MLMITNPFFTPAEIVKPVKASDAKLMVTPAYHVDKVRDFTNKNDMRIICIDSFPDSCLYFSKLTRVGDKVKCPTIEI
>EUC15175-RA
MAAKDKKQEFIFRSILPEIDIPSHLPLYLYCFQNKSRIKSRTCLIDESTGNTFTYADVELNAKKVAAGLLNLGGIGQGDVIMLLLSNLPEFAFALLGISYLGAISTTVNPCFSADEIFKQVESSRPKLIITEACYVEKVRKFAGIRVICTDSSPAGCLNFSDLKGDEIPATKIKSDDVAVIPYTSGTTGFPKGVMLTHKGLITNIAQQVDGENPNINITTNDVLICVLPMYHMYSMNCVLLCGIRAGATIVIMKKFEINKMLEVIQKYRVTIAHLVPPIVLSIDKSPVVGAAPLGKELERAVRAKLPNAKLGQGHGMTEGGPVISLSLSFAKEPVEMKSGSSGVVLRNAEMKIVDPNTGISLPPNQPGEVCVRGDNVMKGYLYDPEVPTTKMDNGWLQTGDFGYVDDDQELFIIERFKELIKYKEFQVAPAELEAILISHPNISDVAVVPLQDEAVGEVPVAFVVRATGSIITEDQVKQFVSEKVEVYKRINRVIFIDSIPKVASGKILRKELSGRLK
>EUC13566-RA
MDESTGDTFTYADVELNARKVAAGLLNLGGIGQDDVIMLLLSNLSEFAFALLDISYLGAISTIVNPCFKAKEIFKQVESSRSKFIISEACYVEKIRKFARIKVICTDSLPAGCLNFSDLKGDEISATKIKPVDVTVVL
>EUC13567-RA
MNLCFSAEEIFKQVESSRPKLIITEACYVEKVRKFAGIKVICTDSSPAGCSNFSNLKGGKISATKINPDDVAVTPYTSRTTGFPKRVMLTHKGLITNIAQQVDNKNPNINITTDGVLICILPMYHMYSMNCVLFVWDPGRSDDCDHEEV
>EUC11437-RA
MTMLSTVETPPQKPEPSSPVVPSILAPPQSHIFTSKLPPIPIPNHLPLHTYCFQDLSHDDNRTCLIAGARTFSFAQTHLLCRKVASGLSKQGIRKGDVIMVLLQNCPEFVFSFMGASILGAATTTANPFYTTAEIFKQFQASEAKLIITQSQYVDKLRDPGEDYPKLGEDFTVITVDDPPEKCLHFSVLSEEADELESSKVSIDPNDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGDNPNLHLTTEDVVLCVLPLFHIFSLNSVLMCALRAGAAVLLMPKFEIGALLEQIQRHRVSVAAVVPPLVLALAKNPMVDSFDLSSIRAVLSGAAPLGKELENALRTRLPQAIFGQVKKKREDLPTRIRNTNICHQFLTFSVXXXXXXAFAKQPFPTKSGSCGTVVRNAELKVVDPDNGSSLPHNQPGEICIRGPQIMKGYLNDEEATARTIDVDGWLHTGDIGYVDDDDEVFIVDRVKELIKFKGFQVPPAELEALLVSHSSIADAAVVPQKDEGAGEVPVAFVVPSEGADLTEEAVKEFIAKQVVFYKKLHKVYFVDSIPKSPSGKILRKDLRSKLPLPSSSLS
>EUC18014-RA
MEFKSEQKDIIFRSKLPDIDIPKHLSLHSYCFEKISEFGSRPCLINGATDEVYSYADVERISRQFAAGLNRNGVSKGETIMILLPNSPEFVFAFLGASFRGAVSTMANPLFTPAEVVKQAKAAGVKLIVTQACHVGKVRDFANENDVRIACIDSPPDGCLHFSELTRPGDEDECPAVEIQPDDVVCLPYSSGTTGLPKGVMLTHKGQVTSVAQQVDGENPNLYMHSDDVLLCVLPLFHVYSLNSILFCGLRVGAAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLMAIAKSPVVDKYDLSSIRTVMSGAAPLGKELEDTVRAKIPNAKLGQGYGMTEAGQSRSR
>EUC23429-RA
MAAIEEHVFRSRYGSVPVPENVLLPDFVLQDVELYADKVAFVDALTGKGYTYGEVSRDVRRFSKALKSLGLRKGRVVVVALPNVAEYPIVALGVMAAGGVFSGTNPAAHASEIKKQVEAADAKLIVTDATTYNKVKSLELPVIVLGDEAVEGTICWNELLEAGDRAGTDTINEVVLQTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVGPELVGQVTTLGLIPFFHIYGLAGICCATLRNKGKVVVMGRYELRAFLNALIEHEVTFAPIVPPIILGLVKNPIVDEFDLGRLKLRSIMTAAAPLAPEILSEFEKKFPGVDVQEAYGMTEHSCITLTHGDPSKGQDISKKHSVGFILPNLEVKFIDPDTGLSLPMNTPGEICVRSQCVMLGYYNNEKETAHTIDQNGWLHTGDIGYIDDDGDIFLVDRIKELIKFKGFQ
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University