Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Euclidium syriacum
Species name
Euclidium syriacum is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Euclidium_syriacum.HIDH.fa
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>Eusyr.0024s0042.1.v1.1
MESEIASELLPFARVYKDGRVERFTGTEIIPASLDSTNDVLSKDVLYSPEHNLSVRLFLPHKAAELAAGNKLPLLIYIHGGAWIIESPFSPIYHPYLTEVVKSANCLAVSIQYRRAPEDPVPAAYEDSWSAIQWIFSHFGGSGPEDWINKYADFDRVFIAGDSAGGNMTHHMAMRAGKEKLEPRIKGVTVVHPAFWGTDPVDEQDVQDRETRSGIAEVWEKIASPNSVNGTDDPLFNVVGSGSDFSGLGCEKVLVAVAGEDVFVRQGLAYAAKLEKSGWKGTVEVMEEQGEGHVYHLQNPNSEKASKFMKKFVEFIVG
>Eusyr.0024s0043.1.v1.1
MLRRIICSSSLPSHSLFFRLIRPSSRSYLTLSSSPIFIGVSSRNLRRLPNPTTLRSICSQSPSDLVSEHPPFVRIYKDGRVERLSGTEIVPASLEPQNGVVSKDVVYSPEHNLSARLFLPHKATEITAGNKLPLLIYIHGGAWIIESPFSPIYHNFLTEVVKPANCLAVSIQYRRAPEHPVPAAYDDVWSAIRWIFSHSGGSGPENWINKYADFNKVFLAGDSAGGNMSHHMAMRAGKEKLEPRIKGTAIVHPAFWGKEPVDEHDVQDREIRSRVAEVWEKLVCPNSVDGTDDPWFNVVGSSSDFSGLGCEKVLVAVAGKDLFVRQGLGYAEKVKKSGWKGEVEVMEEEDEDHCFHLLSPNSENAPKFMKKFVEFITG
>Eusyr.0119s0243.1.v1.1
MGATTLTHLTTINPNNTNIHGPVVDEVEGVIKVYKDGHVERSQLVPCVGPSIALELGVACSDVHIDKLTDVWARLYVPMMTKSSVSQLPLLVYFHGGGFCVGSASWSCYHEFLVKLSARSRCLIMSVNYRLAPENPLPAAYEDGVNALLWLNKTRNDNFWAKVCDFNRIFLVGDSAGANIAHQVAARLADADLAVLNPLKIEGTVLIQPFFGGEARTESERRLVGNHKSSMLTLAASDAYWRLALPRGADRDHPYCKPVNNLVVRTLVCVSEMDVLMDREMEMMCDDETVMKRVVYRGVGHAFQILGKSQLAQTRTLEMLSHINAFIHNYDSFC
>Eusyr.0120s0032.1.v1.1
MDSEIVADYAPLLRIYKSGRIERLMGETTVPPSLDPQNGVVSKDVVYSPDNNLSVRIYLPEKAAETGEKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASDCVAVSVDYRRAPEHPVPIPYEDSWTALKWVFTHMAGSGQENWLNKNADFNKVFLAGDSAGANIAHHMAMRAAKAKLTPELGDSGISGIILVHPYFWSKTPIDEKESKDVTLRTKIEGIWTMASPNSKDGSDDPLINVVQSESSDLSGLGCGRVLVMVAAKDALARQGWGYAAKLEKSGWKGKVEAVESEEEDHVFHLMKPDCEKALEAMQKFAGFLRGDN
>Eusyr.0126s0046.1.v1.1
MDSEIEIDRPPWIRVYKNGRIERLADETMVPPSLDPQNSVVSKDVVYSPQKNLSVRIYLHQKAVETGEKKLPLLVYFHGGGFILGTAFCPTYHTFITSVVAGGADCIAVSVDYRRAPKHPIPIAYEDSWDALKWIFAHTAGSGPEDWLNLHADFSKVFLAGDSAGANIVHHMGIRAGKEKPISRNFEISGIILIHPYFWSKTPIDDEETKDVAVRMIFNKLWEIASPNSENGVDDPWINVVGSELSDISALGCERVLVMVAEKMS
>Eusyr.0126s0045.1.v1.1
MDSEIEIDISPWIRVYKNGRIERLADETMVPPSLDPQNNVVSKDVVYSPEKNLSVRIYLHQKTVETGEKKLPLLVYFHGGGFILGTAFCPTYHNFLTSVVAGGADCIAVSVDYRRAPEHLIPIAYEDSWDALKWIFAHTAGSGPEDWLNLHADFSKVFLAGDSAGANIAHHMAIRAGIEKPISRNFKISGIILIHPYFWSKTPIDDEETKDVAVRTIYYKLWEIVSPNSENGVDDPWINVVGSESSDISGLGCERVLVMVAGKDDLMRQGLGYVAKLEKSGWEGKVEVVEAKDEIHVFHLMNPDTDNTRRLRQKIAEFLKIA
>Eusyr.0126s0049.1.v1.1
MDSDSELAFDYSPRFRIYKNGRIERLGIQTIVPPSPNPENSVVSVDTVYSPEKNLSLRIYLPQKTFEIGAETKKLPLLVYFHGGGFIMETAFSPIYHTFLTSTVLAADCIIVSVDYRRAPEHPIPAAYEDSWEAVKWIFAHIAGTGPEDWLNKHADFSKVFLAGDSAGANIAHHMGIRAGKEKLTFNDEPENFKISGMVLFHPYFWSKAPIDEEEMTEVRARTYMEGLWEIASPNSKNGVDDPWINVVGSDSSDLSGLSCGRVLVMVAGDDLLVRQGWGYAAKLEKSGWEGEVEVMETKDEGHVFHLRNPDSDNANLVLQRFAEFVKRNTS
>Eusyr.0127s0198.1.v1.1
MDSEIAFDNSPGYRVYKSGRIERLIGEKTVPPSLNPQNGVISKDAVYSLEKNLSLRIYLPEKVADTGEKLPVLVYFHGGGFVIETAFSPTYHTFLTSTVAAADCLAISVDYRRAPEYPIPIPYEDSWDSLNWVVSHIAGSGPENWINKHADFSKLFLAGDSAGGNITHHLTIRAKREKLESEISGIILIHPYFWGKTPIDELETRDATRRNNIEGRWRIASPNSKDGADDPLFNVVGSESSDLSGLGCKRVLVMVAGNDSFVRQGWGYAAKLEKSGWEGEVEVMETKNEGHVFHLKNPNTDNARLLVKKVAEFLNKDREDKKSQDYVSR
>Eusyr.0128s0830.1.v1.1
MATISFSHNHQSSDNRRNGSHHHRHGPVVEEIEGLIKVFNDGCVERPLIVPTVPPTVHPSVKVTAFDIKLSNDTSTRVYIPDAAAAAPSVTLPLLVYFHGGGFCVGSAAWSCYHDFLTSLAVKARCVIVSVNYRLAPEHRLPAAYEDGVNVVLWLAKQKSNVIGGSWLSKCNLSNVFLAGDSAGANIAYQVAVRITSCGRSVNSLNLKGIILIHPFFGGESRTSSEKQQHHDSNSSSALTLSASDTYWRLALPRGANRDHPWCNPFLVSSAKLPAMMVFVAEFDILRDRNLEMWRVMRSHGRRVEAIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFINP
>Eusyr.0128s0550.1.v1.1
MESKKERVSLEILPWLVVHSDGTLERLAGTEVCPPGLDPETRVLSKDIIIDPKTPLSARIYKPDSIQPGQKLPLVLYVHGGAFVISSAGDPSYHTSLNKLVAQANIIAVSVDYRLAPEHPLPTAYEDSWNALQWIQAHKNRPEEGIEPWINDYADLDRFFLVGDSAGANISHHLAFRATQSDPGTGQTVKIKGVGMIHPYFWGTQPIGSEVTDKARKQMVDGWWGFVCPSEKGSDDAWINPFTDKSPELERLGCERVIITVAEKDILKERGKMYYERLIKSKWRGKAEMMETKGKDHVFHMFEPDCDEAMEMLRRLAFFINQTET
MESEIASELLPFARVYKDGRVERFTGTEIIPASLDSTNDVLSKDVLYSPEHNLSVRLFLPHKAAELAAGNKLPLLIYIHGGAWIIESPFSPIYHPYLTEVVKSANCLAVSIQYRRAPEDPVPAAYEDSWSAIQWIFSHFGGSGPEDWINKYADFDRVFIAGDSAGGNMTHHMAMRAGKEKLEPRIKGVTVVHPAFWGTDPVDEQDVQDRETRSGIAEVWEKIASPNSVNGTDDPLFNVVGSGSDFSGLGCEKVLVAVAGEDVFVRQGLAYAAKLEKSGWKGTVEVMEEQGEGHVYHLQNPNSEKASKFMKKFVEFIVG
>Eusyr.0024s0043.1.v1.1
MLRRIICSSSLPSHSLFFRLIRPSSRSYLTLSSSPIFIGVSSRNLRRLPNPTTLRSICSQSPSDLVSEHPPFVRIYKDGRVERLSGTEIVPASLEPQNGVVSKDVVYSPEHNLSARLFLPHKATEITAGNKLPLLIYIHGGAWIIESPFSPIYHNFLTEVVKPANCLAVSIQYRRAPEHPVPAAYDDVWSAIRWIFSHSGGSGPENWINKYADFNKVFLAGDSAGGNMSHHMAMRAGKEKLEPRIKGTAIVHPAFWGKEPVDEHDVQDREIRSRVAEVWEKLVCPNSVDGTDDPWFNVVGSSSDFSGLGCEKVLVAVAGKDLFVRQGLGYAEKVKKSGWKGEVEVMEEEDEDHCFHLLSPNSENAPKFMKKFVEFITG
>Eusyr.0119s0243.1.v1.1
MGATTLTHLTTINPNNTNIHGPVVDEVEGVIKVYKDGHVERSQLVPCVGPSIALELGVACSDVHIDKLTDVWARLYVPMMTKSSVSQLPLLVYFHGGGFCVGSASWSCYHEFLVKLSARSRCLIMSVNYRLAPENPLPAAYEDGVNALLWLNKTRNDNFWAKVCDFNRIFLVGDSAGANIAHQVAARLADADLAVLNPLKIEGTVLIQPFFGGEARTESERRLVGNHKSSMLTLAASDAYWRLALPRGADRDHPYCKPVNNLVVRTLVCVSEMDVLMDREMEMMCDDETVMKRVVYRGVGHAFQILGKSQLAQTRTLEMLSHINAFIHNYDSFC
>Eusyr.0120s0032.1.v1.1
MDSEIVADYAPLLRIYKSGRIERLMGETTVPPSLDPQNGVVSKDVVYSPDNNLSVRIYLPEKAAETGEKLPLLVYFHGGGFIIETAFSPTYHTFLTAAVSASDCVAVSVDYRRAPEHPVPIPYEDSWTALKWVFTHMAGSGQENWLNKNADFNKVFLAGDSAGANIAHHMAMRAAKAKLTPELGDSGISGIILVHPYFWSKTPIDEKESKDVTLRTKIEGIWTMASPNSKDGSDDPLINVVQSESSDLSGLGCGRVLVMVAAKDALARQGWGYAAKLEKSGWKGKVEAVESEEEDHVFHLMKPDCEKALEAMQKFAGFLRGDN
>Eusyr.0126s0046.1.v1.1
MDSEIEIDRPPWIRVYKNGRIERLADETMVPPSLDPQNSVVSKDVVYSPQKNLSVRIYLHQKAVETGEKKLPLLVYFHGGGFILGTAFCPTYHTFITSVVAGGADCIAVSVDYRRAPKHPIPIAYEDSWDALKWIFAHTAGSGPEDWLNLHADFSKVFLAGDSAGANIVHHMGIRAGKEKPISRNFEISGIILIHPYFWSKTPIDDEETKDVAVRMIFNKLWEIASPNSENGVDDPWINVVGSELSDISALGCERVLVMVAEKMS
>Eusyr.0126s0045.1.v1.1
MDSEIEIDISPWIRVYKNGRIERLADETMVPPSLDPQNNVVSKDVVYSPEKNLSVRIYLHQKTVETGEKKLPLLVYFHGGGFILGTAFCPTYHNFLTSVVAGGADCIAVSVDYRRAPEHLIPIAYEDSWDALKWIFAHTAGSGPEDWLNLHADFSKVFLAGDSAGANIAHHMAIRAGIEKPISRNFKISGIILIHPYFWSKTPIDDEETKDVAVRTIYYKLWEIVSPNSENGVDDPWINVVGSESSDISGLGCERVLVMVAGKDDLMRQGLGYVAKLEKSGWEGKVEVVEAKDEIHVFHLMNPDTDNTRRLRQKIAEFLKIA
>Eusyr.0126s0049.1.v1.1
MDSDSELAFDYSPRFRIYKNGRIERLGIQTIVPPSPNPENSVVSVDTVYSPEKNLSLRIYLPQKTFEIGAETKKLPLLVYFHGGGFIMETAFSPIYHTFLTSTVLAADCIIVSVDYRRAPEHPIPAAYEDSWEAVKWIFAHIAGTGPEDWLNKHADFSKVFLAGDSAGANIAHHMGIRAGKEKLTFNDEPENFKISGMVLFHPYFWSKAPIDEEEMTEVRARTYMEGLWEIASPNSKNGVDDPWINVVGSDSSDLSGLSCGRVLVMVAGDDLLVRQGWGYAAKLEKSGWEGEVEVMETKDEGHVFHLRNPDSDNANLVLQRFAEFVKRNTS
>Eusyr.0127s0198.1.v1.1
MDSEIAFDNSPGYRVYKSGRIERLIGEKTVPPSLNPQNGVISKDAVYSLEKNLSLRIYLPEKVADTGEKLPVLVYFHGGGFVIETAFSPTYHTFLTSTVAAADCLAISVDYRRAPEYPIPIPYEDSWDSLNWVVSHIAGSGPENWINKHADFSKLFLAGDSAGGNITHHLTIRAKREKLESEISGIILIHPYFWGKTPIDELETRDATRRNNIEGRWRIASPNSKDGADDPLFNVVGSESSDLSGLGCKRVLVMVAGNDSFVRQGWGYAAKLEKSGWEGEVEVMETKNEGHVFHLKNPNTDNARLLVKKVAEFLNKDREDKKSQDYVSR
>Eusyr.0128s0830.1.v1.1
MATISFSHNHQSSDNRRNGSHHHRHGPVVEEIEGLIKVFNDGCVERPLIVPTVPPTVHPSVKVTAFDIKLSNDTSTRVYIPDAAAAAPSVTLPLLVYFHGGGFCVGSAAWSCYHDFLTSLAVKARCVIVSVNYRLAPEHRLPAAYEDGVNVVLWLAKQKSNVIGGSWLSKCNLSNVFLAGDSAGANIAYQVAVRITSCGRSVNSLNLKGIILIHPFFGGESRTSSEKQQHHDSNSSSALTLSASDTYWRLALPRGANRDHPWCNPFLVSSAKLPAMMVFVAEFDILRDRNLEMWRVMRSHGRRVEAIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFINP
>Eusyr.0128s0550.1.v1.1
MESKKERVSLEILPWLVVHSDGTLERLAGTEVCPPGLDPETRVLSKDIIIDPKTPLSARIYKPDSIQPGQKLPLVLYVHGGAFVISSAGDPSYHTSLNKLVAQANIIAVSVDYRLAPEHPLPTAYEDSWNALQWIQAHKNRPEEGIEPWINDYADLDRFFLVGDSAGANISHHLAFRATQSDPGTGQTVKIKGVGMIHPYFWGTQPIGSEVTDKARKQMVDGWWGFVCPSEKGSDDAWINPFTDKSPELERLGCERVIITVAEKDILKERGKMYYERLIKSKWRGKAEMMETKGKDHVFHMFEPDCDEAMEMLRRLAFFINQTET
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University