Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Euclidium syriacum
Species name
Euclidium syriacum is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Euclidium_syriacum.CHS.fa
Download
>Eusyr.0003s0150.1.v1.1
MGSIDAAELRSEKKPNPGKATILSFGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAIEGQSTVTQRLDICNDAVTEMAVEASKACIKNWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFIGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPISEKPLFELHTAIQNFLPDTEKTIDGRLTEEGINFKLSRELPQIIEDNVENFCKKLIGKAGLTHKDYNEMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKARNTNEGENEWGLILAFGPGVTFEGIAARNLDV
>Eusyr.0010s0183.1.v1.1
MSSRQQIVSSGQQIVPSRQQIVSSRQQIMAVDVSVLRTDAARKAAQKWAQIKSRSNSKITHVVFYTHSRNVVPDDQLTSIIGYRHSVEPFEYRQGSFSESDVFRRFKDLANSYRSAYVIIVCFEITATRSRGSSTSTRAIAAPADKDLEIRHKVACQERDKARVEAYEAKVRAEKEKDRAKRAKRKELEAQALADRAQREALEAKAQLRAERKLRKNALVVNAMFIHM
>Eusyr.0022s0563.1.v1.1
MSASEKQRRVANPGKATVLALGKAFPSNLVSQDNLVEEYLREIKCDDVAIKDKLQHLCKTTTVKTRYTVMSRETMQKYPELATEGSPTIKQRLEIANEAVAQMAYEASLVCIKEWGRGVADITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGMTGLRVAKDIAENNPGSRVLLTTSETMVLGFRPPHKSRPYDLVGAALFGDGAAALIIGADPTESESPFMELHYGLQQFLPGTQGVIDGKLSEEGISFKLGRDLPQKIQDNVEEFCWKLMAKAGSGSLELNDLFWAVHPGGPAILNGLETKLKLKTEKLECSRKALVDYGNASSNTIFYIMDKLRDELDKKKGRGEEWGFGLAFGPGITFEGFLLRNLF
>Eusyr.0126s1352.1.v1.1
MSNSGMNGSIGTKRVANPGKATVLALGKAFPSQVVPQEKLVEGFLRDTKCEDTFIKEKLQHLCKTTTVKTRYTVLTREILEKYPELTTEGTPTIKQRLEIANEAVVEMAYEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIVGANPTESELPFMELHYAVQQFLPGTQNVIDGKISEEGINFKLGRDLPQKIEDNIEEFCKKLMEKAGDDSMEFNDMFWAVHPGGPAILNRLETKLKLESEKLVSSRRALVDYGNVSSNTILYVMEYMRDELKKKGEAAQEWGLGLAFGPGITFEGLLIRSLT
>Eusyr.0128s0578.1.v1.1
MVMGKTSLDEIRKAQRADGPAGILGIGTANPANHVIQSEYPDYYFRITNSEHMTDLKEKFQRMCDKSMIRKRHMHLTEEFLKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAVRAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWVAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLRSVPL
>Eusyr.0135s0108.1.v1.1
MAECKKMGTEQPQDTMAICNGEYTKQEIMFLEVSKLKKEGILKAMKKWGQPKSKITHLVFCTPTFPVMPDPDHHLTKLFGFGHSVQHVSYEQGCFEQNTVLRIFRDFANNNRDTRVLVVCSVITVSRGGEASTTCVSHKGIGKVEIKNLHIHIRGDVHIHVRPEEAEAWFGREGIKLDENAGKPRCHSP
MGSIDAAELRSEKKPNPGKATILSFGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAIEGQSTVTQRLDICNDAVTEMAVEASKACIKNWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFIGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPISEKPLFELHTAIQNFLPDTEKTIDGRLTEEGINFKLSRELPQIIEDNVENFCKKLIGKAGLTHKDYNEMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKARNTNEGENEWGLILAFGPGVTFEGIAARNLDV
>Eusyr.0010s0183.1.v1.1
MSSRQQIVSSGQQIVPSRQQIVSSRQQIMAVDVSVLRTDAARKAAQKWAQIKSRSNSKITHVVFYTHSRNVVPDDQLTSIIGYRHSVEPFEYRQGSFSESDVFRRFKDLANSYRSAYVIIVCFEITATRSRGSSTSTRAIAAPADKDLEIRHKVACQERDKARVEAYEAKVRAEKEKDRAKRAKRKELEAQALADRAQREALEAKAQLRAERKLRKNALVVNAMFIHM
>Eusyr.0022s0563.1.v1.1
MSASEKQRRVANPGKATVLALGKAFPSNLVSQDNLVEEYLREIKCDDVAIKDKLQHLCKTTTVKTRYTVMSRETMQKYPELATEGSPTIKQRLEIANEAVAQMAYEASLVCIKEWGRGVADITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGMTGLRVAKDIAENNPGSRVLLTTSETMVLGFRPPHKSRPYDLVGAALFGDGAAALIIGADPTESESPFMELHYGLQQFLPGTQGVIDGKLSEEGISFKLGRDLPQKIQDNVEEFCWKLMAKAGSGSLELNDLFWAVHPGGPAILNGLETKLKLKTEKLECSRKALVDYGNASSNTIFYIMDKLRDELDKKKGRGEEWGFGLAFGPGITFEGFLLRNLF
>Eusyr.0126s1352.1.v1.1
MSNSGMNGSIGTKRVANPGKATVLALGKAFPSQVVPQEKLVEGFLRDTKCEDTFIKEKLQHLCKTTTVKTRYTVLTREILEKYPELTTEGTPTIKQRLEIANEAVVEMAYEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIVGANPTESELPFMELHYAVQQFLPGTQNVIDGKISEEGINFKLGRDLPQKIEDNIEEFCKKLMEKAGDDSMEFNDMFWAVHPGGPAILNRLETKLKLESEKLVSSRRALVDYGNVSSNTILYVMEYMRDELKKKGEAAQEWGLGLAFGPGITFEGLLIRSLT
>Eusyr.0128s0578.1.v1.1
MVMGKTSLDEIRKAQRADGPAGILGIGTANPANHVIQSEYPDYYFRITNSEHMTDLKEKFQRMCDKSMIRKRHMHLTEEFLKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAVRAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWVAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRKKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLRSVPL
>Eusyr.0135s0108.1.v1.1
MAECKKMGTEQPQDTMAICNGEYTKQEIMFLEVSKLKKEGILKAMKKWGQPKSKITHLVFCTPTFPVMPDPDHHLTKLFGFGHSVQHVSYEQGCFEQNTVLRIFRDFANNNRDTRVLVVCSVITVSRGGEASTTCVSHKGIGKVEIKNLHIHIRGDVHIHVRPEEAEAWFGREGIKLDENAGKPRCHSP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University