Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Euclidium syriacum
Species name
Euclidium syriacum is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Euclidium_syriacum.4CL.fa
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>Eusyr.0017s0303.1.v1.1
MSPQEAITVQKQSSADVIFRSKLPDIHIPNHLPLHDYIFENISEFAAKPCLINGPTGEVYSYADVHATSREIAAGLRRLGVNQHDVIMLLLPNSPEFVFTFFGASFLGAITTAANPFYTPAEISKQAKASAAKLIVTQSRYADKVLDLGVPIICTDSSDVIPEGCLRFSELTHSREEDRDTRVSSGTEISPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFNREDVILCVLPMFHIYALNSIMLCSLRVGAAILIMPKFEITLLLEQIQRCKVTVAMVVPPIVLAMAKSSETETEKYDLSSIRIIKSGAAPLGKELEDAISAKFPNARLGQGYGMTEAGPVLAMSLGFAKEPFSVKSGACGTVVRNAEMKIVDPDTGDSLPRNNAGEICIRGHQIMKGYLNDPAATASTIDKDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELESLLIAHPEISDVAVVAMKEEAAGEVPVAFVVRSKDSNVSEDEIKQFVSKQVVFYKRISRVFFTDSIPKAPSGKILRKDLRARLAIGLMG
>Eusyr.0017s0304.1.v1.1
MVLQQQTLFLTKQTDEEEPSPDFIFRSKLPDILIPNHLPLTDYVFQKFSGDSATATSKTCLIDGVTGRIFTYADVYLNSRRIAAGIHRLGIRHRDVVMLLLPNSPEFALSFLGIAYLGAVATTANPLYTQPEITKQAKDSAAKMIITKQCYVDKLTILRNDGVLIVCVEDDGDDVNSSKAVDGCVSFTGLIQTDETELPKPEISPDDAVAMPYSSGTTGLPKGVIITHKGLVTSIAQKVDGENPNVNFTVDDVILCFLPMFHIYALDALMLSVMRTGAALLIVPRFELKLVLELIQKYKVTAVPVAPPVVLALVKSPDTERYDLSSVRMMLSGAATLKKDLEDAVRLKFPNSIFGQGYGMTESGTVAKSLAFAKIPFKTKSGSCGTVIRNAEMKVVDTITGISLPRNQSGEICVRGHQLMKGYLNDPEATARTIDEEGWLHTGDIGYVDDDDEMFIVDRLKELIKFKGYQVAPAELEALLISHPHIDDAAVVPMKDEVADEVPVAFVVRSEGSQLSEDDVKSFVNQQVVHYKRIKMVFFIEAIPKAASGKILRKELRAKLETEYSK
>Eusyr.0018s0201.1.v1.1
MEDQKQDNEHIFRSLYPAVPIPDNLTLPEFVLQGVEEFTDKVAFVEAVTGKAFTYGEVARDTKRLAKALTSLGLRKGQVMVVVLPNVVEYGIIALGIMTAGGVFSGANPTGLVSEIKKQVEASGAKGIITDATNYEKVKTFGLPVIVVGEEKIEGAVNWKDLLEAVDKTGDTFENKQKILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRPEMIGQIVTLGLIPFFHIYGIVGICFATMKNKGKVVAMSRFDLRLFLNALIVNEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGKSLPKNTSGELCVRSQCVMQGYFKNKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVMNPKAKEKEEDILNFVASNVAHYKKIRAVHFVDTIPKSLSGKIMRRLLRDKILNINNK
>Eusyr.0117s0084.1.v1.1
MEKSGYGRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYSSKPALIDSDSGHSLSFSQLKSAVSRLAHGFLRLGIRKNDAVLIFAPNSYQFPLCFLAVTAIGGIFTTVNPLYTVNEVSKQINDSKPKIIISVPQLFDKIKGFNLPIVLLGSGESVQIPDSNSKILRFNDVMELSEPNSDLPVVEIKQSDTAVLLYSSGTTGASKGVELTHGNFIAAALMVTMDPELMGEYNGVYLCFLPMFHVFGLAVISFSQLQRGNCLVSMAKFELETLLKNIEKYRVTNLWLVPPVFLALSKHTAVKKYDLSSLKYIGSGAAPLGKDLMEECGRNIPNVMLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETKKCQPPNQLGEIWVRGPNMMKGYLNNPKATKETIDTKGWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQIAPAELEDLLVSHPEILDAAVIPLPDEEAGEVPIAFVVRSPNSSITEEDVQKFIAKQVASYKRLRRVSFINVVPKSAAGKILRRELVQHVRSKM
>Eusyr.0118s1544.1.v1.1
MAPQQEVMQKQSSVSDIIYRSKLPDIYIPNHLPLHEYIFQNISEFASKPCLINGPTGHVYTYSDVHAISRRIAAGFKKLGVNQNDVVMILLSNCPEFVLSFLAASFRGATATAANPFFTEAEIAKQAKASNSKLIITESRYVDKIKTLQNDDGVIIVCIDDDESVPIPEGCLRFTELSQSDEIDSTETPISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPIVPPIVLAIAKSPESEKYNLSSIRVVKSGAAPLGKELEDAVSAKFPNAKLGQGYGMTEAGPVLAMSLGFAKESFPVKSGACGTVVRNAEMKIVDPDTGISLPKNERGEICIRGHQIMKGYLNNPAATAETIDKEGWLHTGDIGLIDDDDELFIVDRLKEIIKYKGFQVAPAELEALLISHPDITDVAVVGVKEEASGEVPVAFVVKSKDSNVSEDDVKQFVSKQVIYYKRIKKVYFAETIPKAPSGKILRKDLRAKLANGLVN
>Eusyr.0119s0176.1.v1.1
MTTAALQELQIHTPVDPSPAVVSGDAPPTPRIFRSKLPDIYIPNHLPLHAYCFEKLSSISDKPCLIVGSSGKSYTYGETHNLCRRVAAGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVATTANPFYTSQEIYKQLKSSGAKLIITHSHYVDKLKNIEEIDIGKDLTVITTDENPTPENCLPFSTLTDETNNIPESESVDVGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLKPDDVVLCVLPLFHIYSLNSVLLNSIRSGATVLLMHKFEIGALLDLIQRHRVTMAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDSLRHRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRLSLGYNQPGEICIRGQQIMKEYLNDPEATTATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELEALLINHHSVADAAVVPQNDEVAGEVPVAFVVRSNGNDITEEDIKEYIAKQVVFYKRLHKVFFVTSIPKSPSGKILRKDLKAKLC
MSPQEAITVQKQSSADVIFRSKLPDIHIPNHLPLHDYIFENISEFAAKPCLINGPTGEVYSYADVHATSREIAAGLRRLGVNQHDVIMLLLPNSPEFVFTFFGASFLGAITTAANPFYTPAEISKQAKASAAKLIVTQSRYADKVLDLGVPIICTDSSDVIPEGCLRFSELTHSREEDRDTRVSSGTEISPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFNREDVILCVLPMFHIYALNSIMLCSLRVGAAILIMPKFEITLLLEQIQRCKVTVAMVVPPIVLAMAKSSETETEKYDLSSIRIIKSGAAPLGKELEDAISAKFPNARLGQGYGMTEAGPVLAMSLGFAKEPFSVKSGACGTVVRNAEMKIVDPDTGDSLPRNNAGEICIRGHQIMKGYLNDPAATASTIDKDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELESLLIAHPEISDVAVVAMKEEAAGEVPVAFVVRSKDSNVSEDEIKQFVSKQVVFYKRISRVFFTDSIPKAPSGKILRKDLRARLAIGLMG
>Eusyr.0017s0304.1.v1.1
MVLQQQTLFLTKQTDEEEPSPDFIFRSKLPDILIPNHLPLTDYVFQKFSGDSATATSKTCLIDGVTGRIFTYADVYLNSRRIAAGIHRLGIRHRDVVMLLLPNSPEFALSFLGIAYLGAVATTANPLYTQPEITKQAKDSAAKMIITKQCYVDKLTILRNDGVLIVCVEDDGDDVNSSKAVDGCVSFTGLIQTDETELPKPEISPDDAVAMPYSSGTTGLPKGVIITHKGLVTSIAQKVDGENPNVNFTVDDVILCFLPMFHIYALDALMLSVMRTGAALLIVPRFELKLVLELIQKYKVTAVPVAPPVVLALVKSPDTERYDLSSVRMMLSGAATLKKDLEDAVRLKFPNSIFGQGYGMTESGTVAKSLAFAKIPFKTKSGSCGTVIRNAEMKVVDTITGISLPRNQSGEICVRGHQLMKGYLNDPEATARTIDEEGWLHTGDIGYVDDDDEMFIVDRLKELIKFKGYQVAPAELEALLISHPHIDDAAVVPMKDEVADEVPVAFVVRSEGSQLSEDDVKSFVNQQVVHYKRIKMVFFIEAIPKAASGKILRKELRAKLETEYSK
>Eusyr.0018s0201.1.v1.1
MEDQKQDNEHIFRSLYPAVPIPDNLTLPEFVLQGVEEFTDKVAFVEAVTGKAFTYGEVARDTKRLAKALTSLGLRKGQVMVVVLPNVVEYGIIALGIMTAGGVFSGANPTGLVSEIKKQVEASGAKGIITDATNYEKVKTFGLPVIVVGEEKIEGAVNWKDLLEAVDKTGDTFENKQKILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRPEMIGQIVTLGLIPFFHIYGIVGICFATMKNKGKVVAMSRFDLRLFLNALIVNEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGKSLPKNTSGELCVRSQCVMQGYFKNKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVMNPKAKEKEEDILNFVASNVAHYKKIRAVHFVDTIPKSLSGKIMRRLLRDKILNINNK
>Eusyr.0117s0084.1.v1.1
MEKSGYGRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYSSKPALIDSDSGHSLSFSQLKSAVSRLAHGFLRLGIRKNDAVLIFAPNSYQFPLCFLAVTAIGGIFTTVNPLYTVNEVSKQINDSKPKIIISVPQLFDKIKGFNLPIVLLGSGESVQIPDSNSKILRFNDVMELSEPNSDLPVVEIKQSDTAVLLYSSGTTGASKGVELTHGNFIAAALMVTMDPELMGEYNGVYLCFLPMFHVFGLAVISFSQLQRGNCLVSMAKFELETLLKNIEKYRVTNLWLVPPVFLALSKHTAVKKYDLSSLKYIGSGAAPLGKDLMEECGRNIPNVMLMQGYGMTETCGIVSVEDPRLGKRNSGSAGMLAPGVEAQIVSVETKKCQPPNQLGEIWVRGPNMMKGYLNNPKATKETIDTKGWVHTGDLGYFNEDGNLYVVDRIKELIKYKGFQIAPAELEDLLVSHPEILDAAVIPLPDEEAGEVPIAFVVRSPNSSITEEDVQKFIAKQVASYKRLRRVSFINVVPKSAAGKILRRELVQHVRSKM
>Eusyr.0118s1544.1.v1.1
MAPQQEVMQKQSSVSDIIYRSKLPDIYIPNHLPLHEYIFQNISEFASKPCLINGPTGHVYTYSDVHAISRRIAAGFKKLGVNQNDVVMILLSNCPEFVLSFLAASFRGATATAANPFFTEAEIAKQAKASNSKLIITESRYVDKIKTLQNDDGVIIVCIDDDESVPIPEGCLRFTELSQSDEIDSTETPISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPIVPPIVLAIAKSPESEKYNLSSIRVVKSGAAPLGKELEDAVSAKFPNAKLGQGYGMTEAGPVLAMSLGFAKESFPVKSGACGTVVRNAEMKIVDPDTGISLPKNERGEICIRGHQIMKGYLNNPAATAETIDKEGWLHTGDIGLIDDDDELFIVDRLKEIIKYKGFQVAPAELEALLISHPDITDVAVVGVKEEASGEVPVAFVVKSKDSNVSEDDVKQFVSKQVIYYKRIKKVYFAETIPKAPSGKILRKDLRAKLANGLVN
>Eusyr.0119s0176.1.v1.1
MTTAALQELQIHTPVDPSPAVVSGDAPPTPRIFRSKLPDIYIPNHLPLHAYCFEKLSSISDKPCLIVGSSGKSYTYGETHNLCRRVAAGLYKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVATTANPFYTSQEIYKQLKSSGAKLIITHSHYVDKLKNIEEIDIGKDLTVITTDENPTPENCLPFSTLTDETNNIPESESVDVGGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLKPDDVVLCVLPLFHIYSLNSVLLNSIRSGATVLLMHKFEIGALLDLIQRHRVTMAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDSLRHRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRLSLGYNQPGEICIRGQQIMKEYLNDPEATTATIDEEGWLHTGDIGYVDEDDEIFIVDRLKEVIKFKGFQVPPAELEALLINHHSVADAAVVPQNDEVAGEVPVAFVVRSNGNDITEEDIKEYIAKQVVFYKRLHKVFFVTSIPKSPSGKILRKDLKAKLC
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University