Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Eucalyptus grandis
Species name
Rose gum (Eucalyptus grandis) is a species of eudicot in the family Myrtaceae (myrtle family).
Species info
Gene sequence info
Eucalyptus_grandis.ROMT.fa
Download
>rna-XM_010054096.3
MAVLAQTGFVSQGKSAANNDHEQLGLTYSLTPISRAILKGEPGGLSPMVSFILGPVIQDPLHSLGEWLKSESPSPCTPFVMKHGKSLWEYAAQDEGLNQSVNEAMASDGPMIARLMMEKRGRQLFQGLRTVVDVGGGSGGLAREAAEAFPQVEWRVLDLPHVVAGLEGTRNLKFVGGDMFNAVPSADAVLLKWILHDWSDEESVKILKRCKEAVLSNSKKGKVIIIDIVIGDESEEDEASMGIKLCFDMLMMTVVQGKERNEKEWANLFQEAGFTEYRITPLEGIRSLIEVYP
>rna-XM_010071874.2
MDRAYNAETNESESETFRAHAHVWRHAFNFISSMSLKCAIELGVPDALHRRGHPATLPELATALSVPTSKTTVLGRLVAVLVHMGFLSRQKAAPESNGMSEHEADELGFEYSLTPASCAIVKGQPLDLSPIVLLTLDPIFVDPFHCMSEWLKSDSETGSPSLRTPLHMKHGKSMWEIKAQDKKFNQRMNRAMASDGPVMARLIMDKCGGRLFEGLRTAIDVGGGTGGLARELAEAFPEMEWTVLDLPRVVAGLERTRNLKYVGGDMFEAVPPADAVLLKWVLHDWSDEESVKILKRCKEAITSNSERGKAIIVEAVIGDGPEEGETMKLFYDMIMMVGTTGKERNEKEWAKLLREAGFIDYKITPLAGFRSLIEAYT
>rna-XM_010054016.3
MDCPTGEHTGELLKAQAHVWNSVFNLTGMFLKCAVQLNIPDAIHKHGQPMTVSELVAALQIQPTKSGCVHRLMRVLVHSGFFEERRLEPSDQIGYALNHASELLVKDSPFNSAAMVLAMLDPSVMKAYDCLSAWFLNNDRTTFETAYGMKVWEYTAQDPKFNQLFNDAMASDSRLLATVVINECAGVFEDINSLVDGGGTGLMAKAIADAFTLECTVFDLPHVVADLPGSNNMKYVGGDMFKGIPPADAIILKMVLHDWNDEDCIKILKQCKSAISSTKDKVGKVIIVETVMKNHDNAKDEKFMELELAVDIAMMMAHASRERTEKEWAELFFDAGFGGYKMYPVLGFRSLIEVYP
>rna-XM_010054028.3
MDSGNGDGNATAGELLQAQAHVWNHLFSYITSLCLKCALQLGIPDLIHDHGRPMTLPELLSALRIPPAKAHGLRRIMRVLVHSGYFELRDLEDADRRSGYTLTAASRLLLKHNPLSPAPFVLSAFHPFFMGPWQHLNAWLGDGEGVTPTMIEMAHGGPAWEVIRRDPEVDGLFSGAMDNDSRLMAKAVVETCGGAFVGLSSVTDVGGRSGTMGKAITEAFPNLEYTVLDQPNIVDGLVGSERLKFVGGDMFVEIPPADAILLKWVLHDWSDEKCIDILKRSKEAVSGRGGIGKVIIIDVVVGNQPDDHRSTETQLFWDMLMMTYDAKERDEKEWEKLFVDAGFSGYKIISHLGLRSLIEVYP
>rna-XM_010071851.3
MDWGNGDGNATAGELLQAQAHVWNHLFSYITSLCLKCALQLGIPDLIHDHGRPMTLPELVSALRIPPAKAHGLRRLMRVLVHSGYFKLRDLEDADHRSGYTLTAASRLLLKHNPLSPAPFVLGALHPFIMGTWQHLKAWLGDGEGVTPSMIEMAHGGPTWEVMRRDPEVDGLFSGAMDNDSRLMAKAVVETCGGVFDGLSSVTDVGGRSGTMGKAITEAFPHLEYTVLDQPNVVDGLVGSERLKFVGGDMFVEIPPADAILLKWVLHDWSDEKCIEILKRSKEAVSGRDGIGKVIIIDVVVGNQPDDHRSTETQLFWDMLMMMYDAKERDEKEWEKLFVDAGYSGYKIISHLGLRSLIEVYP
>rna-XM_010071864.3
MDAANSGEMSESEIFRAYAHVWTHTFNFISSMSLKCAIELGIPDTLHRCGHPMTLPDLATALSVPASKAAFLGRLVAVLVHTGFLSCQKPAPRNNPISEDTADELGFEYSLTPASRVIVKGQPWDMSPIAMVMLNSLLVEPFHCLSEWLKSDSEVGPSSLRTPFDMKHGKGLWEYASQDENLNRCLNEGMASDGPMMARLIMDKCGRRLFEGLRTAVDVAGGIGGLARELAKAFPEMEWTVLDLVHVVASMEGTRNLKYVGGDMFEAIPPADAILLKWILHDWSDEESVKILKRCKEAITSNGKMGKVMIVEIVIGDELEEFHTTKLFYDMMLMGCLTGKERNEKEWAKLFREAGFSDYKITPLAGFRSLIEVYP
>rna-XM_010042610.3
MDMVNGEMGSQQLLAQAHIWNHIFNFINSMCLKCAIQLGIPDTIHHHGQPMNLDALVSALQIHPSRAHCVDRLMRILVHSGFFEQKKLAPDGRGAYVLNRVSKLLLTDNPCNVVPFALSMLDPTLINPWHGLSAWFHNRVDPTPFEMVQGMSFWRYAGQEPGLNRLFNDGMASDARLVASMVVNEHKGVFEGITSLVDVGGGTGTTAKAIANAFPHMECTIFDLPHVVANLEVSENVRCVPGDMFESIPPADAIILKWILHDWSDEDAVKILKRCKEALGKGKGKKQKVIIIDMVMDNTKSDKETVETQLFYDMLMMTLASGRERNEAEWAKLFVAAGFGDYKITPVLGLRSLIEVYP
>rna-XM_010071953.3
MDMVNGEMGSQQLLAQAHIWNHIFNFINSMCLKCAIQLRIPDTIHHHDQPMTLDALVSALQIHPSRAHCLDRLMRILVHSGFFEQKKLAPDGRGAYVLNRVSKLLLTDNPSNVAPFALSMLDPIVINPWHGLSAWFHNHVDPTPFEMVQGMSIWRYVGQEPGLNRLFNDGMATDARLVASMVVNEHKGMFEGITSLVDVGGGTGTTAKAIANSFPHMECTIFDLPHVVANLEVSENVRCVPGDMFESIPPADAIILKWILHDWSDEDAVKILKRCREALGKGEGKKKKVIIIDMVMDNTKSDKEMVETQLFYDMLMMTLVSGRERNEAEWAKLFVTAGFGDYKITPALGLRSLIEVYPS
>rna-XM_010071882.3
MKHGKSLWEYTAHDEGLNRSLNDAMASDGPMIARLMMEKRGRQLFQGLRTVVDVGGGSGGLAREAAEAFPQVEWMVLDLPHVVAGLEGTRNLKFVGGDMFNAVPSADAVLLKWILHDWSDEESVKILKRCKEAVLSNDKKGKVMIIDIVIGDESEEDEASMGIKLCFDIMMTTLFLGKERNEKEWANLFQEAGFTEYRITPLEGFRSLIEVYP
>rna-XM_010054086.3
MESVDNEVMSESAIVQAYAHVWTHAFNSISSMSLKCAIELGIPDALHHHGHPMTLPELAAALSVPTSKVTFLRRLMAVLAQTGFISQGKSAAENDHEQLGLTYSLTSISRVILKGEPGGLSPMVSFILGPIIQDPLHCLGKWLKSESPSPCTPFVMKHGKSLWEYTAHDEGLNQSLNEAMASDGPMIARLMMEKRGRQLFQGLRTVVDVGGGRGGLAREAAEAFPQVEWMVLDLPHVVAGLEGTRNLKFVGGDMFNAVPSADAVLLKWILHDWSDEESVKILKRCKEAVLSNDKKGKVMIIDIVIGDESEEDEASMGIKLCFDIMMATLVLGKERNEKEWANLFQEAGFTEYRITPLEGFRSLIEVYP
>rna-XM_010059745.3
MDMVNGEMGSQQLLAQAHIWNHIFNFISSMCLKCAIQLGIPDTIHHHGQPMTLDALVSALQIHPSRAHCVDRLMRILVHSGFFEQKKLAPDGQGAYVLNRVSKLLLTDNPSNVAPFALSVLDPILINPWHGLSAWFHNHADPTPFEMVQGMSFWRYAGQEPGLNRLFNDGMASDARLVASMVVNEHKGVFEGITSLVDVGGGTGTMAKAIANSFPHMECTIFDLPHVVANLEVSENVRCVPGDMFEAIPPADAIILKWILHDWSDEDAVKVLKRCREALGKGEGKKKKVIIIEMVMDNTKSDKEMVETQLFYDMLMMTLTSGRERNEAEWAKLFVAAGFGDYKITPVLGLRSLIEVYPS
>rna-XM_010025666.3
MDLAKGDGDAAASELLRAQAHIWTIFSFINSMCLKCAIQLGIPDLIHGHGRPMTLPELVSALHVQPTRAHCIRRLMRVLVHSGFFEVRDLDGVDRQTGYALTGASRLLVKHDPLTLAPFALFALEPYSMDPWQYLSAWLGDREDVPSTLDMAHGVPAWEYVRRNPEVASSFHEAMASDSRLIAKLVGDTCGGVFEGMSSVVDVGGGSGTMAKAIADAFPHLTCTVFDLSAVVDGLVGSERLKFVGGDMFVEIPQADAILLKWILHDWSDEKCIEILKRSKEAVSGRGKVGKVILIEIVVGNQTEDHRSTETQLFFDMWMMNLNGKERSEKEWEKLFVDAGFSGYKIISHLGLRSLIEIYP
>rna-XM_010025665.3
MNLGNGDRGATASELLQAQALIWNHTYSFIKSVCLKWAIELAIPDIIHHHGRPMTLQELVSALHVQPTKAHCIRRLMRILVHSGLFGLRDLEEADDQTGYVLTCVSRLLVKDNALSAEPFALLAVRLLPKGRWQDLSAWLRDGEDVHPTAFEMAHGVPAWEAWRSPEVSSLFNEAMASDSSLIARVVVDTCGGVFEGLSSVVDVGGGTGTMGKAITEAFPHLECTVFDQPHVVDGLVGSERVKFVGGNMFVEIPPADAVILKWILHDWSDEKCIEILKRCREAVSCQGKVGKIIMIDMVVGSQTEDHESTETQLFFDMLMMVTFNAKERDEKEWAKLFADAGFSGYEIVSHLGLRSLIEIYP
>rna-XM_010034551.2
MNLGNGDGDATASELLQAQARIWNHTYSFVKSVCLRWAIELAIPDVIHHHGRPMTLWELVSALHVQPTKVHCIRRLMRVLVHSGLFELRDLEEADGQTGYVLTCVSRLLVKDNALSAAPFALLALRSLPKGRWPDPSAWLRDGEDVRPIIGEEMARHVPAWGVWRSPEVSSLFNEAMASDSSLIARVVVDTCGGVFEGLNSVVDVGGGTGTMGKAITEAFPHLECTVLDRPHVVDGLVGSERLKFVGGDMLVEIPPADAVILKLVLHDWSDEKCIEILNRCREAVSGQGKVGKVIMIDMVLGSLTEDHGSTETQLLFDISMMAFFNAKERDEKEWAKLFADAGFSGYEIVSHLGLRSLIEIYP
MAVLAQTGFVSQGKSAANNDHEQLGLTYSLTPISRAILKGEPGGLSPMVSFILGPVIQDPLHSLGEWLKSESPSPCTPFVMKHGKSLWEYAAQDEGLNQSVNEAMASDGPMIARLMMEKRGRQLFQGLRTVVDVGGGSGGLAREAAEAFPQVEWRVLDLPHVVAGLEGTRNLKFVGGDMFNAVPSADAVLLKWILHDWSDEESVKILKRCKEAVLSNSKKGKVIIIDIVIGDESEEDEASMGIKLCFDMLMMTVVQGKERNEKEWANLFQEAGFTEYRITPLEGIRSLIEVYP
>rna-XM_010071874.2
MDRAYNAETNESESETFRAHAHVWRHAFNFISSMSLKCAIELGVPDALHRRGHPATLPELATALSVPTSKTTVLGRLVAVLVHMGFLSRQKAAPESNGMSEHEADELGFEYSLTPASCAIVKGQPLDLSPIVLLTLDPIFVDPFHCMSEWLKSDSETGSPSLRTPLHMKHGKSMWEIKAQDKKFNQRMNRAMASDGPVMARLIMDKCGGRLFEGLRTAIDVGGGTGGLARELAEAFPEMEWTVLDLPRVVAGLERTRNLKYVGGDMFEAVPPADAVLLKWVLHDWSDEESVKILKRCKEAITSNSERGKAIIVEAVIGDGPEEGETMKLFYDMIMMVGTTGKERNEKEWAKLLREAGFIDYKITPLAGFRSLIEAYT
>rna-XM_010054016.3
MDCPTGEHTGELLKAQAHVWNSVFNLTGMFLKCAVQLNIPDAIHKHGQPMTVSELVAALQIQPTKSGCVHRLMRVLVHSGFFEERRLEPSDQIGYALNHASELLVKDSPFNSAAMVLAMLDPSVMKAYDCLSAWFLNNDRTTFETAYGMKVWEYTAQDPKFNQLFNDAMASDSRLLATVVINECAGVFEDINSLVDGGGTGLMAKAIADAFTLECTVFDLPHVVADLPGSNNMKYVGGDMFKGIPPADAIILKMVLHDWNDEDCIKILKQCKSAISSTKDKVGKVIIVETVMKNHDNAKDEKFMELELAVDIAMMMAHASRERTEKEWAELFFDAGFGGYKMYPVLGFRSLIEVYP
>rna-XM_010054028.3
MDSGNGDGNATAGELLQAQAHVWNHLFSYITSLCLKCALQLGIPDLIHDHGRPMTLPELLSALRIPPAKAHGLRRIMRVLVHSGYFELRDLEDADRRSGYTLTAASRLLLKHNPLSPAPFVLSAFHPFFMGPWQHLNAWLGDGEGVTPTMIEMAHGGPAWEVIRRDPEVDGLFSGAMDNDSRLMAKAVVETCGGAFVGLSSVTDVGGRSGTMGKAITEAFPNLEYTVLDQPNIVDGLVGSERLKFVGGDMFVEIPPADAILLKWVLHDWSDEKCIDILKRSKEAVSGRGGIGKVIIIDVVVGNQPDDHRSTETQLFWDMLMMTYDAKERDEKEWEKLFVDAGFSGYKIISHLGLRSLIEVYP
>rna-XM_010071851.3
MDWGNGDGNATAGELLQAQAHVWNHLFSYITSLCLKCALQLGIPDLIHDHGRPMTLPELVSALRIPPAKAHGLRRLMRVLVHSGYFKLRDLEDADHRSGYTLTAASRLLLKHNPLSPAPFVLGALHPFIMGTWQHLKAWLGDGEGVTPSMIEMAHGGPTWEVMRRDPEVDGLFSGAMDNDSRLMAKAVVETCGGVFDGLSSVTDVGGRSGTMGKAITEAFPHLEYTVLDQPNVVDGLVGSERLKFVGGDMFVEIPPADAILLKWVLHDWSDEKCIEILKRSKEAVSGRDGIGKVIIIDVVVGNQPDDHRSTETQLFWDMLMMMYDAKERDEKEWEKLFVDAGYSGYKIISHLGLRSLIEVYP
>rna-XM_010071864.3
MDAANSGEMSESEIFRAYAHVWTHTFNFISSMSLKCAIELGIPDTLHRCGHPMTLPDLATALSVPASKAAFLGRLVAVLVHTGFLSCQKPAPRNNPISEDTADELGFEYSLTPASRVIVKGQPWDMSPIAMVMLNSLLVEPFHCLSEWLKSDSEVGPSSLRTPFDMKHGKGLWEYASQDENLNRCLNEGMASDGPMMARLIMDKCGRRLFEGLRTAVDVAGGIGGLARELAKAFPEMEWTVLDLVHVVASMEGTRNLKYVGGDMFEAIPPADAILLKWILHDWSDEESVKILKRCKEAITSNGKMGKVMIVEIVIGDELEEFHTTKLFYDMMLMGCLTGKERNEKEWAKLFREAGFSDYKITPLAGFRSLIEVYP
>rna-XM_010042610.3
MDMVNGEMGSQQLLAQAHIWNHIFNFINSMCLKCAIQLGIPDTIHHHGQPMNLDALVSALQIHPSRAHCVDRLMRILVHSGFFEQKKLAPDGRGAYVLNRVSKLLLTDNPCNVVPFALSMLDPTLINPWHGLSAWFHNRVDPTPFEMVQGMSFWRYAGQEPGLNRLFNDGMASDARLVASMVVNEHKGVFEGITSLVDVGGGTGTTAKAIANAFPHMECTIFDLPHVVANLEVSENVRCVPGDMFESIPPADAIILKWILHDWSDEDAVKILKRCKEALGKGKGKKQKVIIIDMVMDNTKSDKETVETQLFYDMLMMTLASGRERNEAEWAKLFVAAGFGDYKITPVLGLRSLIEVYP
>rna-XM_010071953.3
MDMVNGEMGSQQLLAQAHIWNHIFNFINSMCLKCAIQLRIPDTIHHHDQPMTLDALVSALQIHPSRAHCLDRLMRILVHSGFFEQKKLAPDGRGAYVLNRVSKLLLTDNPSNVAPFALSMLDPIVINPWHGLSAWFHNHVDPTPFEMVQGMSIWRYVGQEPGLNRLFNDGMATDARLVASMVVNEHKGMFEGITSLVDVGGGTGTTAKAIANSFPHMECTIFDLPHVVANLEVSENVRCVPGDMFESIPPADAIILKWILHDWSDEDAVKILKRCREALGKGEGKKKKVIIIDMVMDNTKSDKEMVETQLFYDMLMMTLVSGRERNEAEWAKLFVTAGFGDYKITPALGLRSLIEVYPS
>rna-XM_010071882.3
MKHGKSLWEYTAHDEGLNRSLNDAMASDGPMIARLMMEKRGRQLFQGLRTVVDVGGGSGGLAREAAEAFPQVEWMVLDLPHVVAGLEGTRNLKFVGGDMFNAVPSADAVLLKWILHDWSDEESVKILKRCKEAVLSNDKKGKVMIIDIVIGDESEEDEASMGIKLCFDIMMTTLFLGKERNEKEWANLFQEAGFTEYRITPLEGFRSLIEVYP
>rna-XM_010054086.3
MESVDNEVMSESAIVQAYAHVWTHAFNSISSMSLKCAIELGIPDALHHHGHPMTLPELAAALSVPTSKVTFLRRLMAVLAQTGFISQGKSAAENDHEQLGLTYSLTSISRVILKGEPGGLSPMVSFILGPIIQDPLHCLGKWLKSESPSPCTPFVMKHGKSLWEYTAHDEGLNQSLNEAMASDGPMIARLMMEKRGRQLFQGLRTVVDVGGGRGGLAREAAEAFPQVEWMVLDLPHVVAGLEGTRNLKFVGGDMFNAVPSADAVLLKWILHDWSDEESVKILKRCKEAVLSNDKKGKVMIIDIVIGDESEEDEASMGIKLCFDIMMATLVLGKERNEKEWANLFQEAGFTEYRITPLEGFRSLIEVYP
>rna-XM_010059745.3
MDMVNGEMGSQQLLAQAHIWNHIFNFISSMCLKCAIQLGIPDTIHHHGQPMTLDALVSALQIHPSRAHCVDRLMRILVHSGFFEQKKLAPDGQGAYVLNRVSKLLLTDNPSNVAPFALSVLDPILINPWHGLSAWFHNHADPTPFEMVQGMSFWRYAGQEPGLNRLFNDGMASDARLVASMVVNEHKGVFEGITSLVDVGGGTGTMAKAIANSFPHMECTIFDLPHVVANLEVSENVRCVPGDMFEAIPPADAIILKWILHDWSDEDAVKVLKRCREALGKGEGKKKKVIIIEMVMDNTKSDKEMVETQLFYDMLMMTLTSGRERNEAEWAKLFVAAGFGDYKITPVLGLRSLIEVYPS
>rna-XM_010025666.3
MDLAKGDGDAAASELLRAQAHIWTIFSFINSMCLKCAIQLGIPDLIHGHGRPMTLPELVSALHVQPTRAHCIRRLMRVLVHSGFFEVRDLDGVDRQTGYALTGASRLLVKHDPLTLAPFALFALEPYSMDPWQYLSAWLGDREDVPSTLDMAHGVPAWEYVRRNPEVASSFHEAMASDSRLIAKLVGDTCGGVFEGMSSVVDVGGGSGTMAKAIADAFPHLTCTVFDLSAVVDGLVGSERLKFVGGDMFVEIPQADAILLKWILHDWSDEKCIEILKRSKEAVSGRGKVGKVILIEIVVGNQTEDHRSTETQLFFDMWMMNLNGKERSEKEWEKLFVDAGFSGYKIISHLGLRSLIEIYP
>rna-XM_010025665.3
MNLGNGDRGATASELLQAQALIWNHTYSFIKSVCLKWAIELAIPDIIHHHGRPMTLQELVSALHVQPTKAHCIRRLMRILVHSGLFGLRDLEEADDQTGYVLTCVSRLLVKDNALSAEPFALLAVRLLPKGRWQDLSAWLRDGEDVHPTAFEMAHGVPAWEAWRSPEVSSLFNEAMASDSSLIARVVVDTCGGVFEGLSSVVDVGGGTGTMGKAITEAFPHLECTVFDQPHVVDGLVGSERVKFVGGNMFVEIPPADAVILKWILHDWSDEKCIEILKRCREAVSCQGKVGKIIMIDMVVGSQTEDHESTETQLFFDMLMMVTFNAKERDEKEWAKLFADAGFSGYEIVSHLGLRSLIEIYP
>rna-XM_010034551.2
MNLGNGDGDATASELLQAQARIWNHTYSFVKSVCLRWAIELAIPDVIHHHGRPMTLWELVSALHVQPTKVHCIRRLMRVLVHSGLFELRDLEEADGQTGYVLTCVSRLLVKDNALSAAPFALLALRSLPKGRWPDPSAWLRDGEDVRPIIGEEMARHVPAWGVWRSPEVSSLFNEAMASDSSLIARVVVDTCGGVFEGLNSVVDVGGGTGTMGKAITEAFPHLECTVLDRPHVVDGLVGSERLKFVGGDMLVEIPPADAVILKLVLHDWSDEKCIEILNRCREAVSGQGKVGKVIMIDMVLGSLTEDHGSTETQLLFDISMMAFFNAKERDEKEWAKLFADAGFSGYEIVSHLGLRSLIEIYP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University