Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Erythranthe guttata
Species name
Spotted monkey flower (Erythranthe guttata) is a species of eudicot in the family Phrymaceae.
Species info
Gene sequence info
Erythranthe_guttata.HIDH.fa
Download
>rna-XM_012975497.1
SSPFPIHSTEATAAAAGNSTEEAILYDIYPFIRVYKDGRVQRFIGQDFSPPSTDPATAVRSKDVVFSTNPNLSARLYLPAAAFSSNKKKLPLLIYFHGGGFFTESAFSPTYHRHLNSLVAKSNIAAVSVNYRLAPEHPLPAAYQDSWLALNWTLSHSAAGAAAEPWLNNHADFQRVYLGGDSAGGNIAHHISTRVGSENPYPNVKFGGMFLNCPYFLGKKPVGNELSPEYSYAETLMKKLWVHAYPNSPAGLDDPLVNPGMDPGLKRVGCKRVLVYVAGNDVLRFRGWYYKERLEKSLWGGEVKVVEVEGENHVFNLINPTTPKAISMLNVLANFLNNHH
>rna-XM_012977739.1
MRRRRMAAMKAVHEQNNMGLQISSKDKDQTHLHRSSSLVLVEKIDGLIRVYKDGHVDRPQIVPCVGCSLAPDLGVTCGDTIIDKYTNVWARVYVPRKKKQQQQQLPLLVYFHGGGFCVGSASWICYHEFLAKLAASVNCVVVSVNYRLAPENPLPAAYDDGVVALGWLRKQQFAGGGEWWTERCDFSSVCLAGDSAGANIAYNVAVRVATPPLPLKGLVLIQPFFGGEARTDSEKYMVQPPRSALTLAASDTYWRLSLPAGADRDHPWCNPAAAGELPAARVGVLVCVSEMDILRDRNMEFCERLRNNMKGCGGGGGGGGGRKVEQVVSKGVGHAFQILDKSPLSQTRVLELISHINNFIISTCM
>rna-XM_012981285.1
MASDPKEIVLDLSPFFRLLRDGTCQRIGPAQFLPPSDDPNAAVRSKDVTVDAETGVSVRIFAPRRRDPPQKLPLVVYIHGGAFCVGSVASPVFHNFISNLVEKANVVAVAVEYRLAPENPLPIPFDDSWTAFQWIASHAAADGGGGGPEPWLNDHADFRRVFVGGESAGATIANDVAIRAGVRGFAGVEIVGLFLVHPFFGGKEEDKLYKSLCPTSSARDDDPRLYPAVDPRIGQMAGRRVVFLVAEKDFLRERGKGYYEGLKKSAWAGEAEIMESEGVGHCFHLFDTTSDKAVAITHRLVELFNTYYQFKQKGQITAISELWSNYEKSPSVTVTHSISVSPEMDSKPSQITHDFPPFFRVHNTGHVERYIEHDFVPPSHDPLTGVNSRDVVVVPENNVSARIFLPKTTGGDSKLPLLIYIHGGAFSIESAFSSTYHNYAVSLASESRSVVVSIEYRLAPEHPIPACYDDSYAVVKWLDSHSRPGNGPDPWINEYADFERVYLAGDSAGANIAHNMVIRAKNNPEHGPNFKFAGLILIHPFFGIGKPDKLWNYICPDTTGSDDPRLNPTADPDLLSKLDCERVLVCVSERDFLRKRGLNFYQELKKSEWKGVIEFFETEGKEHVFHLIDPVCEKAVALLNRIVRFIDSGGVHVLSHF
>rna-XM_012981344.1
MAAPQTANEVLHDFFPLMREYKDGRVERYWATELVPPSLDAETLTQSKDVVISPETDLSARIFLPRNADPANKLPLLVYFHGGGFVVESAFSPLYHNHLNLLAAEANVVAVSVNYRLAPEYPLPAAYEDAWLALKWIASRSINDEWIGKYADLNRVYLGGDSAGGNIASNLAVRFGGEGKEKLAGINLVGVFLNCPFFCGVDPLENEDKHEVFPKTYLDKIWKYACPDTAGSDDPRINPDKDPNLWRFGCTRVLVYAAEKDVLKGRGWLFKETMMKRGWNGNIEVVEVEGEDHIFSVLFPKSENSMAMLKKVASFINNE
>rna-XM_012981343.1
MSCKKISLYFLLISHLLSFTLAATNSSDILYDIYPYVRVYKNGTVERFIGTQTLPPSLDPINGVRSKDIYGIAPKLNVSARLYLPKNTVNPKKKLPLLVYFHGGAFFTESAFSPTYYNHMNSLVAKANVVAVSVNYRLAPENPLPIGYEDSWLALKWVFSHSEGGNGTDPWLKSYVDYGRVYLGGDSAGANIAHNMAIRAGLDKTGRVKLLGMFLNCPHFWGKKLIGSEGGGDPQRRAVMESIWIHAYPNSTGFDDPLSNPAKDPNLSKMDGKRVLVYVAEKDILKDRGLYYKRTLRRSKWNGIVKAVEVKGEDHVFNLRFPNTTKAMKMLNHLASFLNRD
>rna-XM_012981345.1
MAENYSDEILYDFTPMLKAYKDGRIERLTGREFVPASLDLTTGVNSKDVLISPEIGVAARIYLPGDANPAAKLKLPVVVYFHGGGFVVDSPFSPLYHKHLNHLVAESNAIAVSVDYRLAPEHPLPTAYEDSWLALKWIFSGEAQNEEWIRDYADLDRVYLGGDSAGGNIAHHLAIRVGSEQNTGSNINLRGIFLNCPFFGGSDPIGGEMALVKTIVDNLWVFVHPKEFPGHDGPWINPAKDPRVSGLGCRRVLVYVAEKDYLKDRGWYYKETLEKSGWFGEIEVVEVEGEDHVFSVFSPDGENGLAMIKKVASFINH
>rna-XM_012981511.1
MAEIYSDEVLYDFTPMLKAYKNGRVERLTGEQFVPASIDPATRVKSKDVQISPELGVAARIYIPGDANPDTKLKLPVVVYFHGGGFAVESPFSPLYHKHLNYLVAESNAIAVSVDYRLAPEYPLPTAYDDSWLALKWVFSDEAQNEEWIKDYADLGRVYLGGDSAGGNIAHHLAIRVGSEQGTNISLRGIFLNCPFFGGKDPVGVESSEEMVLWKKFVDNLWVFVHPKEFPGYDDPWINPAKDPRVSGLGCSRVLVYVAEKDYLKDRGWYYKETLEKSGWFGEIEVVEVKGEVHVFSVFSPDGENGLAMIKKVASFINH
>rna-XM_012983248.1
MKTVVHDVPPYLRVYEDGTVERFIGTETTPAALDPHTGVSSKDVLFLPESGVSARLYRPINPAAAGSHKKLPLVVYFHGGAFCISSSADPKYHDMLNILVNEAQILLVSVDYRIAPENPLPAAYEDSWAALKWAASHLSPEETETGGDIWLRESADFDRVFLAGDSAGANISHHLAIRAGSETHGPELGDKFKIAGVLMVQPYFWGEEAIGVEAENPVFKSVVDKWWRFVCPSDRGCDDPWINPFGDGAPGVDGLACGRVLVCVAGNDVLRERGKLYYQCLVEGKKKMKAELFQTEGEDHVFHILDPTAQNSKILIKRCAQFINGQ
>rna-XM_012982692.1
MSSTTIDENAPAAAASTPPHEVDECRGVLRVYSDGSIWRSNKPSFEMPVPDDGSVLWKDAVFDAAHSLQLRLYKPAKPSSPKLPIFYYIHGGGFCIGSRAWPNCQNYCFKLASQLQAVVISPDYRLSPENRLPAAIEDGYSAVKWLQSQATADEPDTWLTDAADFSRVFISGDSAGGNIAHNLAVRFGAGSAELTPVRVKGYVYLAPFFGGTVRTKFEDQGPKEAFLNIDLIDRFWRLSIPIGETTDHPLVNPFGPVSPNLETMDLDPILVIVGGSDLLKDRAEEYAKKLKKWGKKIEYVEFEGQQHGFFTINPDSKPSQELMLVIKKFIEGNSV
>rna-XM_012996247.1
MAATINELDYEFPPHIKVYKNGHVERLTGTDTTPPGTDPQTGVSSKDVKDIIPETEVYVRIYLPKLTTANQKLPLLVYFHGGAFFVYTPSSPLYHNYMNALVAESQVIAVSVHYRRAPEHPLPIGYEDSWAALQWVSAHSSGDGPEPLLNRHADFRRVFLSGDSAGGNIAHNLAMAVGNPDAGVKLEILGIALVDPYFWGPDPIGSEALDPDRKAYVDRLWPLVCPSCPVDDPWIDPVGPGLAGLGCWRVLVCVAEKDILKDRGRLYFDALSRSGWLGTVEIHEVEGEGHCFHLHDLNGERAKERMTRMAAFFNRDMPPAYASTLANSIEP
>rna-XM_012998514.1
MNTTTTTKEVLTDLSPVIKVYTDGTVERLLHSPDVPPSPEDTTTGVYSKDATISPTVSARIHLPKPTHPTQKLPVLVYYHGGGFCIGSAFSHLDHRLMTVLSAEAGALVISVEYRLTPEHPLPAAYEDSWDALKWISSHSVDTQTNSEKEKWISNHADFSRISIGGDSAGGNIAHNLALRAGSEPLPGNVKIAGAILSHPYFWGSNPIGNEPKEDIDQSLLYQLWLLAYPSAPGGIDNPLINPFCDGAPSLSGLGCSRLMVCVSEMDILTGRAKVYAEKVKESGWNGVVEVVEIEGEGHCFHIFGIENEKAKNLIKRWATFISQ
>rna-XM_013002566.1
MSIVAESPGFIQVFSNGAVKRFSPPTAAPSLSNNNKYKSKDVIIDPSKPITARIFLPQHHSSQSQSKSIPILVYFHGGGFCIGSTTWLGYHTFLGNLSSTAGIIVLSVDYRLAPENKLPIPYEDCFAALQWLAAAASNTEPWLQDADLSRIFLSGDSAGGNIAHHVTVKAIETNINIRVKGLLPIHPYFGSEARTELEMEEASAGEVAMNDMFWKLSLPEGSDRDYYGCNIEKAGLPETTEWGLFPAVVVFVAGLDFLRERGVMYVEFLKKKGVRNVSLVDAEGESHVFHAWNPDSTASFLLQNQISSFIQSL
>rna-XM_012973357.1
MGSLPHIVEDCLGIVQLFSDGSVSRSDDVKFPMEVQDDGSAVWKDCLFDKEHDLSLRLYKPRSPSAAAAAALPILYFFRGGGFCVGSRTWPNCHSCCLRLASALQVLVVAPDYRLAPEHRLPAAVDDAFTAVKWLQSQALLSDDGGADEWLAKGSVDFDRVFVVGDSSGGNLAHHLAVELRRGSPSLAPVRVRGYVLMAPFFGGTVRTKSEAEGPPEQFLNIEILDRFWRLAVPDGNTADHPLANPFGPLSPNLDSAKLDPILVLVGGSEVMKDRIEEYSVKFKEMGKEIEYVVFEAEQHGFFVNQPFSQVANKLLQKINQFMNK
SSPFPIHSTEATAAAAGNSTEEAILYDIYPFIRVYKDGRVQRFIGQDFSPPSTDPATAVRSKDVVFSTNPNLSARLYLPAAAFSSNKKKLPLLIYFHGGGFFTESAFSPTYHRHLNSLVAKSNIAAVSVNYRLAPEHPLPAAYQDSWLALNWTLSHSAAGAAAEPWLNNHADFQRVYLGGDSAGGNIAHHISTRVGSENPYPNVKFGGMFLNCPYFLGKKPVGNELSPEYSYAETLMKKLWVHAYPNSPAGLDDPLVNPGMDPGLKRVGCKRVLVYVAGNDVLRFRGWYYKERLEKSLWGGEVKVVEVEGENHVFNLINPTTPKAISMLNVLANFLNNHH
>rna-XM_012977739.1
MRRRRMAAMKAVHEQNNMGLQISSKDKDQTHLHRSSSLVLVEKIDGLIRVYKDGHVDRPQIVPCVGCSLAPDLGVTCGDTIIDKYTNVWARVYVPRKKKQQQQQLPLLVYFHGGGFCVGSASWICYHEFLAKLAASVNCVVVSVNYRLAPENPLPAAYDDGVVALGWLRKQQFAGGGEWWTERCDFSSVCLAGDSAGANIAYNVAVRVATPPLPLKGLVLIQPFFGGEARTDSEKYMVQPPRSALTLAASDTYWRLSLPAGADRDHPWCNPAAAGELPAARVGVLVCVSEMDILRDRNMEFCERLRNNMKGCGGGGGGGGGRKVEQVVSKGVGHAFQILDKSPLSQTRVLELISHINNFIISTCM
>rna-XM_012981285.1
MASDPKEIVLDLSPFFRLLRDGTCQRIGPAQFLPPSDDPNAAVRSKDVTVDAETGVSVRIFAPRRRDPPQKLPLVVYIHGGAFCVGSVASPVFHNFISNLVEKANVVAVAVEYRLAPENPLPIPFDDSWTAFQWIASHAAADGGGGGPEPWLNDHADFRRVFVGGESAGATIANDVAIRAGVRGFAGVEIVGLFLVHPFFGGKEEDKLYKSLCPTSSARDDDPRLYPAVDPRIGQMAGRRVVFLVAEKDFLRERGKGYYEGLKKSAWAGEAEIMESEGVGHCFHLFDTTSDKAVAITHRLVELFNTYYQFKQKGQITAISELWSNYEKSPSVTVTHSISVSPEMDSKPSQITHDFPPFFRVHNTGHVERYIEHDFVPPSHDPLTGVNSRDVVVVPENNVSARIFLPKTTGGDSKLPLLIYIHGGAFSIESAFSSTYHNYAVSLASESRSVVVSIEYRLAPEHPIPACYDDSYAVVKWLDSHSRPGNGPDPWINEYADFERVYLAGDSAGANIAHNMVIRAKNNPEHGPNFKFAGLILIHPFFGIGKPDKLWNYICPDTTGSDDPRLNPTADPDLLSKLDCERVLVCVSERDFLRKRGLNFYQELKKSEWKGVIEFFETEGKEHVFHLIDPVCEKAVALLNRIVRFIDSGGVHVLSHF
>rna-XM_012981344.1
MAAPQTANEVLHDFFPLMREYKDGRVERYWATELVPPSLDAETLTQSKDVVISPETDLSARIFLPRNADPANKLPLLVYFHGGGFVVESAFSPLYHNHLNLLAAEANVVAVSVNYRLAPEYPLPAAYEDAWLALKWIASRSINDEWIGKYADLNRVYLGGDSAGGNIASNLAVRFGGEGKEKLAGINLVGVFLNCPFFCGVDPLENEDKHEVFPKTYLDKIWKYACPDTAGSDDPRINPDKDPNLWRFGCTRVLVYAAEKDVLKGRGWLFKETMMKRGWNGNIEVVEVEGEDHIFSVLFPKSENSMAMLKKVASFINNE
>rna-XM_012981343.1
MSCKKISLYFLLISHLLSFTLAATNSSDILYDIYPYVRVYKNGTVERFIGTQTLPPSLDPINGVRSKDIYGIAPKLNVSARLYLPKNTVNPKKKLPLLVYFHGGAFFTESAFSPTYYNHMNSLVAKANVVAVSVNYRLAPENPLPIGYEDSWLALKWVFSHSEGGNGTDPWLKSYVDYGRVYLGGDSAGANIAHNMAIRAGLDKTGRVKLLGMFLNCPHFWGKKLIGSEGGGDPQRRAVMESIWIHAYPNSTGFDDPLSNPAKDPNLSKMDGKRVLVYVAEKDILKDRGLYYKRTLRRSKWNGIVKAVEVKGEDHVFNLRFPNTTKAMKMLNHLASFLNRD
>rna-XM_012981345.1
MAENYSDEILYDFTPMLKAYKDGRIERLTGREFVPASLDLTTGVNSKDVLISPEIGVAARIYLPGDANPAAKLKLPVVVYFHGGGFVVDSPFSPLYHKHLNHLVAESNAIAVSVDYRLAPEHPLPTAYEDSWLALKWIFSGEAQNEEWIRDYADLDRVYLGGDSAGGNIAHHLAIRVGSEQNTGSNINLRGIFLNCPFFGGSDPIGGEMALVKTIVDNLWVFVHPKEFPGHDGPWINPAKDPRVSGLGCRRVLVYVAEKDYLKDRGWYYKETLEKSGWFGEIEVVEVEGEDHVFSVFSPDGENGLAMIKKVASFINH
>rna-XM_012981511.1
MAEIYSDEVLYDFTPMLKAYKNGRVERLTGEQFVPASIDPATRVKSKDVQISPELGVAARIYIPGDANPDTKLKLPVVVYFHGGGFAVESPFSPLYHKHLNYLVAESNAIAVSVDYRLAPEYPLPTAYDDSWLALKWVFSDEAQNEEWIKDYADLGRVYLGGDSAGGNIAHHLAIRVGSEQGTNISLRGIFLNCPFFGGKDPVGVESSEEMVLWKKFVDNLWVFVHPKEFPGYDDPWINPAKDPRVSGLGCSRVLVYVAEKDYLKDRGWYYKETLEKSGWFGEIEVVEVKGEVHVFSVFSPDGENGLAMIKKVASFINH
>rna-XM_012983248.1
MKTVVHDVPPYLRVYEDGTVERFIGTETTPAALDPHTGVSSKDVLFLPESGVSARLYRPINPAAAGSHKKLPLVVYFHGGAFCISSSADPKYHDMLNILVNEAQILLVSVDYRIAPENPLPAAYEDSWAALKWAASHLSPEETETGGDIWLRESADFDRVFLAGDSAGANISHHLAIRAGSETHGPELGDKFKIAGVLMVQPYFWGEEAIGVEAENPVFKSVVDKWWRFVCPSDRGCDDPWINPFGDGAPGVDGLACGRVLVCVAGNDVLRERGKLYYQCLVEGKKKMKAELFQTEGEDHVFHILDPTAQNSKILIKRCAQFINGQ
>rna-XM_012982692.1
MSSTTIDENAPAAAASTPPHEVDECRGVLRVYSDGSIWRSNKPSFEMPVPDDGSVLWKDAVFDAAHSLQLRLYKPAKPSSPKLPIFYYIHGGGFCIGSRAWPNCQNYCFKLASQLQAVVISPDYRLSPENRLPAAIEDGYSAVKWLQSQATADEPDTWLTDAADFSRVFISGDSAGGNIAHNLAVRFGAGSAELTPVRVKGYVYLAPFFGGTVRTKFEDQGPKEAFLNIDLIDRFWRLSIPIGETTDHPLVNPFGPVSPNLETMDLDPILVIVGGSDLLKDRAEEYAKKLKKWGKKIEYVEFEGQQHGFFTINPDSKPSQELMLVIKKFIEGNSV
>rna-XM_012996247.1
MAATINELDYEFPPHIKVYKNGHVERLTGTDTTPPGTDPQTGVSSKDVKDIIPETEVYVRIYLPKLTTANQKLPLLVYFHGGAFFVYTPSSPLYHNYMNALVAESQVIAVSVHYRRAPEHPLPIGYEDSWAALQWVSAHSSGDGPEPLLNRHADFRRVFLSGDSAGGNIAHNLAMAVGNPDAGVKLEILGIALVDPYFWGPDPIGSEALDPDRKAYVDRLWPLVCPSCPVDDPWIDPVGPGLAGLGCWRVLVCVAEKDILKDRGRLYFDALSRSGWLGTVEIHEVEGEGHCFHLHDLNGERAKERMTRMAAFFNRDMPPAYASTLANSIEP
>rna-XM_012998514.1
MNTTTTTKEVLTDLSPVIKVYTDGTVERLLHSPDVPPSPEDTTTGVYSKDATISPTVSARIHLPKPTHPTQKLPVLVYYHGGGFCIGSAFSHLDHRLMTVLSAEAGALVISVEYRLTPEHPLPAAYEDSWDALKWISSHSVDTQTNSEKEKWISNHADFSRISIGGDSAGGNIAHNLALRAGSEPLPGNVKIAGAILSHPYFWGSNPIGNEPKEDIDQSLLYQLWLLAYPSAPGGIDNPLINPFCDGAPSLSGLGCSRLMVCVSEMDILTGRAKVYAEKVKESGWNGVVEVVEIEGEGHCFHIFGIENEKAKNLIKRWATFISQ
>rna-XM_013002566.1
MSIVAESPGFIQVFSNGAVKRFSPPTAAPSLSNNNKYKSKDVIIDPSKPITARIFLPQHHSSQSQSKSIPILVYFHGGGFCIGSTTWLGYHTFLGNLSSTAGIIVLSVDYRLAPENKLPIPYEDCFAALQWLAAAASNTEPWLQDADLSRIFLSGDSAGGNIAHHVTVKAIETNINIRVKGLLPIHPYFGSEARTELEMEEASAGEVAMNDMFWKLSLPEGSDRDYYGCNIEKAGLPETTEWGLFPAVVVFVAGLDFLRERGVMYVEFLKKKGVRNVSLVDAEGESHVFHAWNPDSTASFLLQNQISSFIQSL
>rna-XM_012973357.1
MGSLPHIVEDCLGIVQLFSDGSVSRSDDVKFPMEVQDDGSAVWKDCLFDKEHDLSLRLYKPRSPSAAAAAALPILYFFRGGGFCVGSRTWPNCHSCCLRLASALQVLVVAPDYRLAPEHRLPAAVDDAFTAVKWLQSQALLSDDGGADEWLAKGSVDFDRVFVVGDSSGGNLAHHLAVELRRGSPSLAPVRVRGYVLMAPFFGGTVRTKSEAEGPPEQFLNIEILDRFWRLAVPDGNTADHPLANPFGPLSPNLDSAKLDPILVLVGGSEVMKDRIEEYSVKFKEMGKEIEYVVFEAEQHGFFVNQPFSQVANKLLQKINQFMNK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University