Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Eriobotrya japonica
Species name
Loquat (Rhaphiolepis bibas) is a species of eudicot in the family Rosaceae (rose family).
Species info
Gene sequence info
Eriobotrya_japonica.CHS.fa
Download
>EVM0011329.1
MGSEHVVQGGFPMKANTGNATILALGKAFPHQLVMQDFLVDGYFKDTNSDDPELKQKLARLCKTTTVKTRYVVMSEEILEKYPELTTEGTPTIKQRLHICNEAVTKMAIEASQACIKKWGRPTSDITHLVYVSSSEARLPGGDLYLAKGLGLSPQTKRVMLYFSGCSGGVAGVRVAKDIAENNPGSRVLLATSETTIIGYKPPSANRPYDLVGVALFGDGAGAMMIGSDPELVSENPLFELHTALQEFLPGTEKTIDGRVTEEGISFKLERELPQIIEDHIEGFCGRLMGVVGYDNKEYNKMFWAVHPGGPAILNRMEKRLDLSPEKLNASRRALADYGNASSNTIVYVLEYIIKESKKMKKEGEGDGGWGMILAFGPGVTFEGILARNLAV
>EVM0040569.1
MEWAITWLYSLVEFPEKFLRIESCVLGMVHKLTCLSSPFQIKSPNHDKIDISFFSCDLYLPNKLGLRNDVGRVSLYFLGCYGGVTGLRSRILLTTSETTILGFRPPNKVRPYDLVGAALFGDGAAAVIIGSNPIAGQESPFMELNYAVQQLFEEGINFKLGRDLPQKINENIEVFCKKLFVAANAEQRDFNELFWAVHPGGPAILNKLESTQKLSSDKLECSRRALMDYGNVSSNTIFYVMENMREELKLKKKEGREEEWGLALAFGPGITFEGILLRSL
>EVM0041914.1
MVTVEEVRKAQRAEGPATVFAIGTATPPNCVDQATYPDYYFRITNSEHKAELKEKFQRMCDKSMIKKRYMYLTEEILRENPSVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPAPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLETTGEGLEWGVLFGFGPGLTVETVVLHSVAA
>EVM0016610.1
MVTVEEVRKAQRAEGPATVFAIGTATPPNCVDQATYPDYYFRITNSEHKAELKEKFQRMCDKSMIKKRYMYLTEEILKENPGVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGADPMPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVVGA
>EVM0027769.1
MVTVEELRKAQRAEGPATVFAIGTATPLNCVDQATFPDYYFRVTKSEHKAELKEKFQRMRDKSMIKKRYMYLTEEILKDNPSVCEYMAPSLDARQDMVVVEVPRLGKEAATKAINEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCSAGGTVLRLAKDLAENNKGARVLVVCSEITAVIFRGSSDTALDNLVGQALFGDGAAAVIIGADPVPEVEKPLFILVSAAQTILPDSDGAIDLHLREVGLTFHLRKDVPELISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRQVLSDYGNMTSGCVLFILDKVRRKSAEKGLKTTGEGLEWGVLFGFGPGLTVETIVLHSVAT
>EVM0016753.1
MVTVEEVRKAQRAEGPATVLAIGTATPSNCVDQTTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPTVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPLPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVESKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLRTTGEGLEWGVLFGFGPGLTVETVVLHSVAA
>EVM0043585.1
MVTVEEVRKAQRAEGPATVMAIGTATPSNCVDQATYPDYYFRITNSEHKVELKEKFQRMCDKSMIKKRYMYLTEEILKENPSVCEYMAPSIDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFNPIGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVGSTA
>EVM0040976.1
MVTVEEVRKAQRAEGPATVLAIGTATPPNCVDQATYPDYYFRITNSEHKVELKEKFQRMCDKSMIKKRYMHLTEEILKENPTVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGSDPVPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVESKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVGA
>EVM0016114.1
MSKVERNGTNGSSGQYRSPSRYAPTPGKATVLALGKAFPSQLIPQDCLVEGYIRDTKCEDSAIKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGTATIKQRLEIANPAVVEMALEASLACIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSSKLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGSNPIAGQESPFMELNYAVQQFLPGTHNVIDGRLSEEGINFKLGRDLPQKIDENIEEFCKKLTVPAKAELKNFNELFWAVHPGGPAILNKMENTLKLSSDKLECSRRALMDYGNVSSNTIFYVMENMREELKLKKKEGRDEEWGLALAFGPGITFEGILLRSL
>EVM0012177.1
MAPLLRGHEPQKERSLAKILALSTGNPPNVYYQKDYLNSCEKSKVRKRHLHISQEILEANPNIGIYGAPSLDARQDMLVPAVSKLGQEPISKITHLVFCTACCVDMPGADFQLNKLIGLNLSVTRTMIYQAGCYAGATVLRHAKDAAENNPGARVLVVCSEIGTIFFHGPDESHLDILVGQALFGDGAAALIVGADPDPETENPLFEIVSCRETIVPNSEHGVVAHILELLEEGFEKIDGFNKDWNSLFYSIHPGGPAIIDQVEENLGLKEGKLRATRHALSEYGNMGAPTVLFILEELRRKSIEEGKSTTGEGPEWGFMIGIGPGFTVETVVLRSEKIA
MGSEHVVQGGFPMKANTGNATILALGKAFPHQLVMQDFLVDGYFKDTNSDDPELKQKLARLCKTTTVKTRYVVMSEEILEKYPELTTEGTPTIKQRLHICNEAVTKMAIEASQACIKKWGRPTSDITHLVYVSSSEARLPGGDLYLAKGLGLSPQTKRVMLYFSGCSGGVAGVRVAKDIAENNPGSRVLLATSETTIIGYKPPSANRPYDLVGVALFGDGAGAMMIGSDPELVSENPLFELHTALQEFLPGTEKTIDGRVTEEGISFKLERELPQIIEDHIEGFCGRLMGVVGYDNKEYNKMFWAVHPGGPAILNRMEKRLDLSPEKLNASRRALADYGNASSNTIVYVLEYIIKESKKMKKEGEGDGGWGMILAFGPGVTFEGILARNLAV
>EVM0040569.1
MEWAITWLYSLVEFPEKFLRIESCVLGMVHKLTCLSSPFQIKSPNHDKIDISFFSCDLYLPNKLGLRNDVGRVSLYFLGCYGGVTGLRSRILLTTSETTILGFRPPNKVRPYDLVGAALFGDGAAAVIIGSNPIAGQESPFMELNYAVQQLFEEGINFKLGRDLPQKINENIEVFCKKLFVAANAEQRDFNELFWAVHPGGPAILNKLESTQKLSSDKLECSRRALMDYGNVSSNTIFYVMENMREELKLKKKEGREEEWGLALAFGPGITFEGILLRSL
>EVM0041914.1
MVTVEEVRKAQRAEGPATVFAIGTATPPNCVDQATYPDYYFRITNSEHKAELKEKFQRMCDKSMIKKRYMYLTEEILRENPSVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPAPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLETTGEGLEWGVLFGFGPGLTVETVVLHSVAA
>EVM0016610.1
MVTVEEVRKAQRAEGPATVFAIGTATPPNCVDQATYPDYYFRITNSEHKAELKEKFQRMCDKSMIKKRYMYLTEEILKENPGVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIIGADPMPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVVGA
>EVM0027769.1
MVTVEELRKAQRAEGPATVFAIGTATPLNCVDQATFPDYYFRVTKSEHKAELKEKFQRMRDKSMIKKRYMYLTEEILKDNPSVCEYMAPSLDARQDMVVVEVPRLGKEAATKAINEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCSAGGTVLRLAKDLAENNKGARVLVVCSEITAVIFRGSSDTALDNLVGQALFGDGAAAVIIGADPVPEVEKPLFILVSAAQTILPDSDGAIDLHLREVGLTFHLRKDVPELISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRQVLSDYGNMTSGCVLFILDKVRRKSAEKGLKTTGEGLEWGVLFGFGPGLTVETIVLHSVAT
>EVM0016753.1
MVTVEEVRKAQRAEGPATVLAIGTATPSNCVDQTTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPTVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPLPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVESKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLRTTGEGLEWGVLFGFGPGLTVETVVLHSVAA
>EVM0043585.1
MVTVEEVRKAQRAEGPATVMAIGTATPSNCVDQATYPDYYFRITNSEHKVELKEKFQRMCDKSMIKKRYMYLTEEILKENPSVCEYMAPSIDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFNPIGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVGSTA
>EVM0040976.1
MVTVEEVRKAQRAEGPATVLAIGTATPPNCVDQATYPDYYFRITNSEHKVELKEKFQRMCDKSMIKKRYMHLTEEILKENPTVCEYMAPSLDARQDMVVVEVPRLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGSDPVPEVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLNEAFKPIGISDWNSLFWIAHPGGPAILDQVESKLALKPEKLEATRQVLSDYGNMSSACVLFILDEVRRKSAEKGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVGA
>EVM0016114.1
MSKVERNGTNGSSGQYRSPSRYAPTPGKATVLALGKAFPSQLIPQDCLVEGYIRDTKCEDSAIKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGTATIKQRLEIANPAVVEMALEASLACIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSSKLGLRNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGSNPIAGQESPFMELNYAVQQFLPGTHNVIDGRLSEEGINFKLGRDLPQKIDENIEEFCKKLTVPAKAELKNFNELFWAVHPGGPAILNKMENTLKLSSDKLECSRRALMDYGNVSSNTIFYVMENMREELKLKKKEGRDEEWGLALAFGPGITFEGILLRSL
>EVM0012177.1
MAPLLRGHEPQKERSLAKILALSTGNPPNVYYQKDYLNSCEKSKVRKRHLHISQEILEANPNIGIYGAPSLDARQDMLVPAVSKLGQEPISKITHLVFCTACCVDMPGADFQLNKLIGLNLSVTRTMIYQAGCYAGATVLRHAKDAAENNPGARVLVVCSEIGTIFFHGPDESHLDILVGQALFGDGAAALIVGADPDPETENPLFEIVSCRETIVPNSEHGVVAHILELLEEGFEKIDGFNKDWNSLFYSIHPGGPAIIDQVEENLGLKEGKLRATRHALSEYGNMGAPTVLFILEELRRKSIEEGKSTTGEGPEWGFMIGIGPGFTVETVVLRSEKIA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University