Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Durio zibethinus
Species name
Durian (Durio zibethinus) is a species of eudicot in the family Malvaceae (mallow family).
Species info
Gene sequence info
Durio_zibethinus.CHS.fa
Download
>rna-XM_022894688.1
MSMAVASVEKIRKAQRAQGPATVLAIGTATPPNCVSQADYPDYYFRITKSEHMTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNMCAYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRIMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIILGADPDTKIERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFSPIGIRDWNSIFWIAHPGGPAILDQVEAKLGLKEEKLSATRHVLSEFGNMSSACVLFILDEMRKKSLEEGKPTTGEGLEWGVLFGFGPGLTVETVVLHSIPTEASR
>rna-XM_022903753.1
MSKTDNNGAPRHHLKRASTPGKATVLAIGKAFPRQLIPQERLVEGYFRDTKCEDVSIKEKLERLCKTTTVKTRYTVMSKEIIDKYPELATEGSSTIKQRLEIANPAVVEMAFEASLACIKEWGRPATDITHIIYVSSSEIRLPGGDLYLASQLGLKNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGTDPITSTESPFMELNYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCRKLMSKASLTEFNDLFWAVHPGGPAILNRLENTLKLNKGKLECSRRALMDYGNVSSNTIFYVMEYMREELKREGGEEWGLALAFGPGITFEGILLRSL
>rna-XM_022905317.1
MVTVEEVRKAQRAEGPATVLAIGTSTPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEIEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSREDGLQTSGEGLEWGVLFGFGPGLTVETVVLHTIPA
>rna-XM_022907370.1
MGSGEAQEGFPKKVNSGKATILALGKAFPHQLVMQDFLVDGYFKNTNCDDPDLRQKLNRLCKTTTVKTRYVVMSEEILKQYPELAIEGLPTVKQRLDICNDAVTEMAVEASRICIRKWGRPISDITHLVYVSSSEARLPGGDLYLAKGLELSPETQRVMLYFMGCSGGVAGLRVAKDIAENNLGSRVLLATSETTIIGFKPPSADRPYDLVGAALFGDGAGAMIIGSDPVFSIERPLFELHTAIQNFLPNTEKTIDGKLTEEGISFKLARELPQIIEDNVEGFCETLMGTVGLTDKDYNKMFWAVHPGGPAILNRIEKRLNLFPEKLNASRRALMDYGNASSNTIVYVMEYMIEESLKRKTESKEESDWGLILAFGPGVTFEGILARNLTVQE
>rna-XM_022910925.1
MSSLENFGRRTSAQGLETILSIGKANPANYISQADFSDYYFRITKSEHIVQLKKKFKRTCEKSMIRKRHFVLTEEIIYQNPNITTYIGKSLDIRQQIIVPEVPKLAPEAASKATITHLMFSAISGVDMPGADYHLTKLLGLPSSIKRVMMYFQGCYASGTILRMAKDFAENNAGARVLVGSSDISFGTFRAPNEHDTPSLIGNAIMGDGAVAMIIGADPDLLKERPLFQIISATENIVPDSHGAIEGHLREAGLSIHLSKDVPKLIANNIESCLAQALNLMSFEDWNRLFWIVHPGNAILDQIELILRLKKEKLLATQHVLSEFGNMFSGTVFFILDKMRRKSLEVGKATTGEGQEWGVLCGLGAGITVDIVVLRSFPTNTFH
>rna-XM_022917883.1
MAMAIASVEEIRKAQRAQGPATVLAIGTATPPNCVAQADYPDYYFRITNSEHMTEIKEKFKRMCDKSMIKNRYMYLTEEILKENPSMCAYMASSLNARQDMVVVEVPKLGKEAATKAIKEWGHPKSKITHLVFCTTSGVDMPGADYQLTKLLGLKPSVKRIMMYQQGCFAGGTVLRLAKDLAENNKGSRVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGADPDTKSERPLFQLVSATQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFSPIGIRDWNSIFWIAHPGGPAILDQVEAKLGLKEEKLRATRHVLSEFGNMSSSCVLFILDEMRKKSLEEGQPTTGEGLEWGVLFGFGPGLTVETVVLHSIPTEATH
>rna-XM_022866211.1
MVTVEEVRRAQRAEGPATVLAIGTSTPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEIEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSKEDGLQTTGEGLEWGVLFGFGPGLTVETVVLHCINA
>rna-XM_022869347.1
MVAQVEKHPISSILVILGTKPTLSLSPYLHVFLWNCLFGGLVVLVIAMQHKRCQWGLGLSWQESFLRQSKILFKDYNKMFWAVHLIGPEILSRLEKLLDLFPGKINASRRALMDYGNASCNTILYVLEYMIELSLKMIF
>rna-XM_022877388.1
MVTVEKVRKAQRAEGPATVLAIGTSTPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEIEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNVEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRRKSKENGLQTTGEGLEWGVLFGFGPGLTVETVVLHSISA
MSMAVASVEKIRKAQRAQGPATVLAIGTATPPNCVSQADYPDYYFRITKSEHMTELKEKFKRMCDKSMIKKRYMYLTEEILKENPNMCAYMASSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRIMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIILGADPDTKIERPLFQLVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFSPIGIRDWNSIFWIAHPGGPAILDQVEAKLGLKEEKLSATRHVLSEFGNMSSACVLFILDEMRKKSLEEGKPTTGEGLEWGVLFGFGPGLTVETVVLHSIPTEASR
>rna-XM_022903753.1
MSKTDNNGAPRHHLKRASTPGKATVLAIGKAFPRQLIPQERLVEGYFRDTKCEDVSIKEKLERLCKTTTVKTRYTVMSKEIIDKYPELATEGSSTIKQRLEIANPAVVEMAFEASLACIKEWGRPATDITHIIYVSSSEIRLPGGDLYLASQLGLKNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGTDPITSTESPFMELNYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEDNIEEFCRKLMSKASLTEFNDLFWAVHPGGPAILNRLENTLKLNKGKLECSRRALMDYGNVSSNTIFYVMEYMREELKREGGEEWGLALAFGPGITFEGILLRSL
>rna-XM_022905317.1
MVTVEEVRKAQRAEGPATVLAIGTSTPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEIEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSREDGLQTSGEGLEWGVLFGFGPGLTVETVVLHTIPA
>rna-XM_022907370.1
MGSGEAQEGFPKKVNSGKATILALGKAFPHQLVMQDFLVDGYFKNTNCDDPDLRQKLNRLCKTTTVKTRYVVMSEEILKQYPELAIEGLPTVKQRLDICNDAVTEMAVEASRICIRKWGRPISDITHLVYVSSSEARLPGGDLYLAKGLELSPETQRVMLYFMGCSGGVAGLRVAKDIAENNLGSRVLLATSETTIIGFKPPSADRPYDLVGAALFGDGAGAMIIGSDPVFSIERPLFELHTAIQNFLPNTEKTIDGKLTEEGISFKLARELPQIIEDNVEGFCETLMGTVGLTDKDYNKMFWAVHPGGPAILNRIEKRLNLFPEKLNASRRALMDYGNASSNTIVYVMEYMIEESLKRKTESKEESDWGLILAFGPGVTFEGILARNLTVQE
>rna-XM_022910925.1
MSSLENFGRRTSAQGLETILSIGKANPANYISQADFSDYYFRITKSEHIVQLKKKFKRTCEKSMIRKRHFVLTEEIIYQNPNITTYIGKSLDIRQQIIVPEVPKLAPEAASKATITHLMFSAISGVDMPGADYHLTKLLGLPSSIKRVMMYFQGCYASGTILRMAKDFAENNAGARVLVGSSDISFGTFRAPNEHDTPSLIGNAIMGDGAVAMIIGADPDLLKERPLFQIISATENIVPDSHGAIEGHLREAGLSIHLSKDVPKLIANNIESCLAQALNLMSFEDWNRLFWIVHPGNAILDQIELILRLKKEKLLATQHVLSEFGNMFSGTVFFILDKMRRKSLEVGKATTGEGQEWGVLCGLGAGITVDIVVLRSFPTNTFH
>rna-XM_022917883.1
MAMAIASVEEIRKAQRAQGPATVLAIGTATPPNCVAQADYPDYYFRITNSEHMTEIKEKFKRMCDKSMIKNRYMYLTEEILKENPSMCAYMASSLNARQDMVVVEVPKLGKEAATKAIKEWGHPKSKITHLVFCTTSGVDMPGADYQLTKLLGLKPSVKRIMMYQQGCFAGGTVLRLAKDLAENNKGSRVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAIIVGADPDTKSERPLFQLVSATQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFSPIGIRDWNSIFWIAHPGGPAILDQVEAKLGLKEEKLRATRHVLSEFGNMSSSCVLFILDEMRKKSLEEGQPTTGEGLEWGVLFGFGPGLTVETVVLHSIPTEATH
>rna-XM_022866211.1
MVTVEEVRRAQRAEGPATVLAIGTSTPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEIEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRKKSKEDGLQTTGEGLEWGVLFGFGPGLTVETVVLHCINA
>rna-XM_022869347.1
MVAQVEKHPISSILVILGTKPTLSLSPYLHVFLWNCLFGGLVVLVIAMQHKRCQWGLGLSWQESFLRQSKILFKDYNKMFWAVHLIGPEILSRLEKLLDLFPGKINASRRALMDYGNASCNTILYVLEYMIELSLKMIF
>rna-XM_022877388.1
MVTVEKVRKAQRAEGPATVLAIGTSTPPNCVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAATRAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRVAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIIGADPVPEIEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNVEKSLVEAFQPLGISDWNSLFWIAHPGGPAILDQVEAKLALKPEKLRATRHVLSEYGNMSSACVLFILDEMRRKSKENGLQTTGEGLEWGVLFGFGPGLTVETVVLHSISA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University