Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Dryas drummondii
Species name
Dryas drummondii is a species of eudicot in the family Rosaceae (rose family).
Species info
Gene sequence info
Dryas_drummondii.OMT.fa
Download
>Drydr70S13849
MGLSNGDQVGATSDHELLQAQAHVWNHIFNFINSMSLKCAVQLGIPDVIHNHGQPITLSNLVAALNLHPSKAHLVQRLMRILVHSDFFAKQQDVYTLTPASRLLLKGGPLSTTPFLLMVLDPVVTAPWHLMSTWLQNGTDIPASTAFEMEHGRPFWELAANEPRFGNLFNEAMEADSHLLAKAMIKECRGVFEGFDSLVDVGGGTGTMAKAIANAFPNINCTVFDLPHVVADMQGTHNLDFVGGDMFDEIPPANAIFLKWILHDWSDEESVKILKRCREAIVSKNGGSDGKVIIVDIVVCVDNKKKKIDKKSSETQLMWDMLMMVCLTGKERTESDWEKLFLAAGFTHYNIAHTLGLRSLIELYP
>Drydr70S13848
MERLSSFRLLNQNSFGKEHATELLQAQAHIWNHIFSFINPMSLNCAIQLGIPDIIKKHGKPITLCHLISSLPIHPSKARCVYRLMRILVHSGFFGQQKLSGIDDDDEEEEGYVLTDASMLLLKDHPMSVRPFLLAMLDPILTKPWHHLTPWFQNEDPTPFHTVHGMTFWDYGNHELGLANFFNDAMASDARLVTSVVIDECKGVFEGLESLVDVGGGTGTVAKAIADAFPHVDCTVLDLPHVVADLQGSDNLKFVGGDMFEAVPPADAILLKWILHDWSDEECVKILKRCKEAITSRKDKKGKVIIIDMMMENQKGDEESIETQLFFDMLMMVLLEGKERNKKEWAKLFSDAGFSDYKITPILGLRSLIEVYP
>Drydr70S13705
MANPLLSLSWSLHFKTGHVHRLMRLMVHSGFFATKQVSKNQKEEEEEAYDLTPSSRLLLNDKVPNLSPFVLAMLDPALATPWQFMGSWFQGNELTPFESAHGMGFWEYGDQNPEFNSLFNGAMASDSGMVNLVVRDCKPVFEGLSSLVDVGGGTGHVARILCEAFPHLKCTVLDLPHVVANLADSMNLKFIGGDIYVPGYPSS
>Drydr70S23986
MDLSNEVSTAAELLEAQSHLWNHIFSFINSMSLKCAVELGIPDIIEKHGKQPITLSQLISSLPIHPSKASFVHRLMRILVHSGFFGQQKLTQSQIGVDNEEQEGYVLTHASRLLLKDHPLSARPLLLAILNPVLTKPWHHFSTWFQNEDHPSPFHMANGMSFWDYGTHEPSVARFFNDAMASDARLVASLVVGDECKGMFEGLESLVDVGGGTGTVAKAIAGAFPTVECTVLDLPHVVADLQASHNLKFVGGDMFQAIPHADAILLKWILHDWNDEECVKILKRCKEAITRKDKRGKVIIIDMIMEGHKGDKKSTETQLFFDMEMMVLATGKERNEKEWAKLFSDAGFSNYKITPSLGLRSLIEVYP
>Drydr164S16792
MEAQAAQVEAEEMLRGQAEIWQQMFGFADSMALKCAVELRIGDIIHSHGGPITLSQITSSISDAPSPDIHYLTRIMRSLVRKKIFTAHHSSNDGETLYGLNPTSRWLLWDSKLSLVPMVLMENHPWQMAPWHYLSQCVKDGGIAFKKAHGSEMWDFASTNPEFNNLFNDAMACAVKIVMGAFLSVYKDGFACIGSLVDVGGGTGGVIAEIVKSHPHIQGINFDLPHVISTAPVHEGVSHVGGDMFEAIPSADTIFIKWVLHDWSDEHCVKILKNCRKAIPEKSGKVIIVDIILEPDSNGPFDETRMVFDILMMAHTTGGKERTQPEWKKLLEEGGFPRYKITKIPTIPSIIEAFPI
>Drydr164S16793
MAMLGEVVKEEEAKLQGQADILQYAYSFVDSMALKCVVELGIADIINSHGKPITLTQIAAQFASPSTDIDHLSRLMRFLVHRKLFKTSTDAKTGDTLYGLTYSSMWLLSNEEKSLAPMVLFANQPNYLASWHWLSQSVKAGGSIFKKAHGSEMWDFASTNPQFNDSFNDGMERTAKIMMGPIYSEYKDGFGCIGSLVDVGGGTGRIIAEIVKSHPHIRGINFDLPHVIATAPVHEGVTHIGGDMFEAIPSAEAIFMKWILHCWGDEDCVKILKNCRKAIPEKNGKVIIVDIVLGIEDKGPFDKRRSVCDVLMMAYTKGGKERTETEWKKLLEEGGFPRYKITKVPTIPSIIEAFPM
>Drydr164S16794
MSSSDYKGFDGVGLIVDVGGGLGTAVAEIVKAHPHIKGINFDLPEVVATAPEYPGVTHLGGDMFDVIPYADAIFMKWIMHNWDDEKCIEILKNCRKAISERSGKIIIADAVVEADGDGLLDTFALRYDLAMMTHTPGGKERSEVEWKKPLAEGGFGRYNIIKTPSLVSIIEAYPY
>Drydr164S01333
MKGYFCVAAILLVLLLVPAAMSSRHIPRPHSRHHGRHLQHSSSTSVVVVPKAKDEGVVGKPGQGVQYFYWEGRAIKGIRGPDTLQVAGSSLPDCSHACGSCTPCRLVMVDEDEIYWRQKKSKEELELPHDSTHVIPQLAQCFINAMVGPRSWAGVFIRSSNKRNEKYVDYPLSSLQEQRLLRLQERLQVPFDETRPDHQEALKALWDAAFPDVALKGLISEQWKEMGWQGSNPATDFRGCGAISLENLLFYARTYPASFHRLLFKQEGKRATWEYPFAVAGINISFMLIKMLDLCSEDEAAFDVLYCIAFEMVDAQWLAMHASYMEFNTIMHDWSDNDCIKILKNCRKAIPETSGKGDGMFDETGFVFDLLMIAHASGGEERTEIESKKLLVSIIEAYPV
>Drydr229S18355
MAFSNEASATELLQAQSHIWNHIFSFINSMSLKCAIQLGIPDIIQKNGKQAITLSQLISSLPIHPTKAGFVHRLMRILVHSGFFGRQKLTQIDDDDEEEEGYVLTDASRLLLKDHPMSVTPLLLLTLDPIMTKPWHYMSTWFQNDDPRPFHMAHGMTFWDYGNREPGVAHRFNDAMARDARLVSSVVVGECKGIFEGLESLVDVGGGTRTVAKAIADAFPNMECTVLDLPHVVADLQGSKNLKYVGGDMFEAVPHADAILLKSILHDWSDEECVKILKRCKEAITSRKDKKGKVIIIDMMMENQKEDEESIETQLFFDMLMMVLVEGKERNKEEWAKLFSDAGFSDYKITPILGLRSLIEVYP
>Drydr380S11165
MEDSTQRELNTREVEEDEQAKVDVWKYVFGFTKMAVVKCAIELGIADAIESHGSPMTLLELSSTLRCAPSPLYRILRFLVHHQIFKEQPTTPLGPKAYAQTPLSRRLMKTGQNSMAALILLESSPVMLAPWHGLSAQIRGTSNPAFEAVHGEDVWSYAATNPAHSQLINEAMACDAKVAVPAVIESCPELFDGVGTIVDVGGGDGTTLRLLVKACPWILGINFDLPHVVCVAGECDKVENVGGDMFDCVPKADAAILMKVLHDWGDNECIQILKKCREAIPEDKGKVIIIEAVIDEKEDEDEKEDKLTDVRLMLDMVMMAHTNTGKERTLKEWEHVLGEAGFSRHTVTPIHAVQSVIQAFP
MGLSNGDQVGATSDHELLQAQAHVWNHIFNFINSMSLKCAVQLGIPDVIHNHGQPITLSNLVAALNLHPSKAHLVQRLMRILVHSDFFAKQQDVYTLTPASRLLLKGGPLSTTPFLLMVLDPVVTAPWHLMSTWLQNGTDIPASTAFEMEHGRPFWELAANEPRFGNLFNEAMEADSHLLAKAMIKECRGVFEGFDSLVDVGGGTGTMAKAIANAFPNINCTVFDLPHVVADMQGTHNLDFVGGDMFDEIPPANAIFLKWILHDWSDEESVKILKRCREAIVSKNGGSDGKVIIVDIVVCVDNKKKKIDKKSSETQLMWDMLMMVCLTGKERTESDWEKLFLAAGFTHYNIAHTLGLRSLIELYP
>Drydr70S13848
MERLSSFRLLNQNSFGKEHATELLQAQAHIWNHIFSFINPMSLNCAIQLGIPDIIKKHGKPITLCHLISSLPIHPSKARCVYRLMRILVHSGFFGQQKLSGIDDDDEEEEGYVLTDASMLLLKDHPMSVRPFLLAMLDPILTKPWHHLTPWFQNEDPTPFHTVHGMTFWDYGNHELGLANFFNDAMASDARLVTSVVIDECKGVFEGLESLVDVGGGTGTVAKAIADAFPHVDCTVLDLPHVVADLQGSDNLKFVGGDMFEAVPPADAILLKWILHDWSDEECVKILKRCKEAITSRKDKKGKVIIIDMMMENQKGDEESIETQLFFDMLMMVLLEGKERNKKEWAKLFSDAGFSDYKITPILGLRSLIEVYP
>Drydr70S13705
MANPLLSLSWSLHFKTGHVHRLMRLMVHSGFFATKQVSKNQKEEEEEAYDLTPSSRLLLNDKVPNLSPFVLAMLDPALATPWQFMGSWFQGNELTPFESAHGMGFWEYGDQNPEFNSLFNGAMASDSGMVNLVVRDCKPVFEGLSSLVDVGGGTGHVARILCEAFPHLKCTVLDLPHVVANLADSMNLKFIGGDIYVPGYPSS
>Drydr70S23986
MDLSNEVSTAAELLEAQSHLWNHIFSFINSMSLKCAVELGIPDIIEKHGKQPITLSQLISSLPIHPSKASFVHRLMRILVHSGFFGQQKLTQSQIGVDNEEQEGYVLTHASRLLLKDHPLSARPLLLAILNPVLTKPWHHFSTWFQNEDHPSPFHMANGMSFWDYGTHEPSVARFFNDAMASDARLVASLVVGDECKGMFEGLESLVDVGGGTGTVAKAIAGAFPTVECTVLDLPHVVADLQASHNLKFVGGDMFQAIPHADAILLKWILHDWNDEECVKILKRCKEAITRKDKRGKVIIIDMIMEGHKGDKKSTETQLFFDMEMMVLATGKERNEKEWAKLFSDAGFSNYKITPSLGLRSLIEVYP
>Drydr164S16792
MEAQAAQVEAEEMLRGQAEIWQQMFGFADSMALKCAVELRIGDIIHSHGGPITLSQITSSISDAPSPDIHYLTRIMRSLVRKKIFTAHHSSNDGETLYGLNPTSRWLLWDSKLSLVPMVLMENHPWQMAPWHYLSQCVKDGGIAFKKAHGSEMWDFASTNPEFNNLFNDAMACAVKIVMGAFLSVYKDGFACIGSLVDVGGGTGGVIAEIVKSHPHIQGINFDLPHVISTAPVHEGVSHVGGDMFEAIPSADTIFIKWVLHDWSDEHCVKILKNCRKAIPEKSGKVIIVDIILEPDSNGPFDETRMVFDILMMAHTTGGKERTQPEWKKLLEEGGFPRYKITKIPTIPSIIEAFPI
>Drydr164S16793
MAMLGEVVKEEEAKLQGQADILQYAYSFVDSMALKCVVELGIADIINSHGKPITLTQIAAQFASPSTDIDHLSRLMRFLVHRKLFKTSTDAKTGDTLYGLTYSSMWLLSNEEKSLAPMVLFANQPNYLASWHWLSQSVKAGGSIFKKAHGSEMWDFASTNPQFNDSFNDGMERTAKIMMGPIYSEYKDGFGCIGSLVDVGGGTGRIIAEIVKSHPHIRGINFDLPHVIATAPVHEGVTHIGGDMFEAIPSAEAIFMKWILHCWGDEDCVKILKNCRKAIPEKNGKVIIVDIVLGIEDKGPFDKRRSVCDVLMMAYTKGGKERTETEWKKLLEEGGFPRYKITKVPTIPSIIEAFPM
>Drydr164S16794
MSSSDYKGFDGVGLIVDVGGGLGTAVAEIVKAHPHIKGINFDLPEVVATAPEYPGVTHLGGDMFDVIPYADAIFMKWIMHNWDDEKCIEILKNCRKAISERSGKIIIADAVVEADGDGLLDTFALRYDLAMMTHTPGGKERSEVEWKKPLAEGGFGRYNIIKTPSLVSIIEAYPY
>Drydr164S01333
MKGYFCVAAILLVLLLVPAAMSSRHIPRPHSRHHGRHLQHSSSTSVVVVPKAKDEGVVGKPGQGVQYFYWEGRAIKGIRGPDTLQVAGSSLPDCSHACGSCTPCRLVMVDEDEIYWRQKKSKEELELPHDSTHVIPQLAQCFINAMVGPRSWAGVFIRSSNKRNEKYVDYPLSSLQEQRLLRLQERLQVPFDETRPDHQEALKALWDAAFPDVALKGLISEQWKEMGWQGSNPATDFRGCGAISLENLLFYARTYPASFHRLLFKQEGKRATWEYPFAVAGINISFMLIKMLDLCSEDEAAFDVLYCIAFEMVDAQWLAMHASYMEFNTIMHDWSDNDCIKILKNCRKAIPETSGKGDGMFDETGFVFDLLMIAHASGGEERTEIESKKLLVSIIEAYPV
>Drydr229S18355
MAFSNEASATELLQAQSHIWNHIFSFINSMSLKCAIQLGIPDIIQKNGKQAITLSQLISSLPIHPTKAGFVHRLMRILVHSGFFGRQKLTQIDDDDEEEEGYVLTDASRLLLKDHPMSVTPLLLLTLDPIMTKPWHYMSTWFQNDDPRPFHMAHGMTFWDYGNREPGVAHRFNDAMARDARLVSSVVVGECKGIFEGLESLVDVGGGTRTVAKAIADAFPNMECTVLDLPHVVADLQGSKNLKYVGGDMFEAVPHADAILLKSILHDWSDEECVKILKRCKEAITSRKDKKGKVIIIDMMMENQKEDEESIETQLFFDMLMMVLVEGKERNKEEWAKLFSDAGFSDYKITPILGLRSLIEVYP
>Drydr380S11165
MEDSTQRELNTREVEEDEQAKVDVWKYVFGFTKMAVVKCAIELGIADAIESHGSPMTLLELSSTLRCAPSPLYRILRFLVHHQIFKEQPTTPLGPKAYAQTPLSRRLMKTGQNSMAALILLESSPVMLAPWHGLSAQIRGTSNPAFEAVHGEDVWSYAATNPAHSQLINEAMACDAKVAVPAVIESCPELFDGVGTIVDVGGGDGTTLRLLVKACPWILGINFDLPHVVCVAGECDKVENVGGDMFDCVPKADAAILMKVLHDWGDNECIQILKKCREAIPEDKGKVIIIEAVIDEKEDEDEKEDKLTDVRLMLDMVMMAHTNTGKERTLKEWEHVLGEAGFSRHTVTPIHAVQSVIQAFP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University