Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Draba nivalis
Species name
Draba nivalis is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Draba_nivalis.4CL.fa
Download
>maker-lg3-snap-gene-66.142-mRNA-1
MITAALHEPQIHKPADTSPADTSPPVSGDAVPPPTPRIFRSKLPDIDIPNHLPLHTYCFEKLSSVSDKPCLIVGSTGKSYSYGETHLICRRVAAGLHKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTANPFYTSQEISKQLKSSGAKLIITQSQYVDKLRNLDDNTKIGQDLTVITTDGPPSENCLPFSTLTEDETDPPMESVHVDGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLNSNDVVLCVLPLFHIYSLNSVLLNSIRSGATVLLMHKFEIGALLDLIQRHRVTIAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDNLRRHLPQAVLGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRLSLGYNQPGEICIRGQQIMKEYLNDPEATSTTIDQEGWLHTGDIGYVDEDDEIFIIDRLKEVIKFKGFQVPPAELEALLINHHSIADAAVVPQNDELAGEVPVAFVVRSNGNEITEEDIKEYIAKQVVFYKRLHKVFFVPSIPKSPSGKILRKDLKAKLC
>maker-lg3-snap-gene-99.280-mRNA-1
MEYQKQDNEYIFRSLYPSVPIPDKLTLPEFVLQGVEEYTEKVAFVEAVTGKAVTYGDVVRDTERLAKALTSLGLRKGQVVVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGVITDATNFEKVKTLGLPVIVLGEEKIEGAVNWKDLLEAGDKCADNNKEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRSDMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRIFLNAMIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPERGQVNAKRNSVGFILPNLEVKFIDPDTGRSLPKNTSGELCVRSQCVMQGYFENKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPVACVVINPKAKEKEEDILNFVAANVANYKKVRAVHFVDSIPKSLSGKIMRRLLRDKIINMKKNELEK
>maker-lg4-snap-gene-82.236-mRNA-1
MVLQQQQQQQQTLLHTKKKKTTTDQQQEPPHDFIFRSKLPDISIPNHLPLIDYVFQNVSGDSTATCLIDGATGRIFSYADVLTNTRRIAAGIHRLGIRHRDVVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTQPEIEKQAKASAAKMIITKPCYVEKLANLQNDGVLIVCVEDDGDDAVSLPDGCVSFKELTRAEERELPKQEISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNVNLTGDDVILCFLPMFHIYALDALMLTAMRCGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFVKSPETERYDLSSVKMMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFETKSGACGTVIRNAEMKVVDTITGISLPRNKSGEICIRGDQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEVFIVDRLKELIKFKGYQVAPAELEALLISHPCINDAAVVPMKDEVADEVPVAFVVRTEGSKLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKDLRAKLETEYPK
>maker-lg4-snap-gene-82.238-mRNA-1
MSPQEPMITDQKQRDDVIFRSKLPDIYIPNHLPLHDYIFENISHFADKPCLINGPTGEVYSYADVHATSRKLAAGLRNLGVDKQDVVMLLLPNSPEFVFTFFAASFLGAITTAANPFFTTAEITKQAKASAVKIIITQSQYAGKIKNLQNDGVSIICTDDDSSSVEGCLPFSELSQLGEAEEQATEISPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYFHREDVILCVLPMFHIYALNSIMLCSLRVGATILIMPKFEISLLLEQIQRCKVTVAMVVPPIVLAMVKSPETEKYDLSLVRVIKSGAAPLGKELEDAVSTKFPNAKLGQGYGMTEAGPVLTMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGNSLPRNKPGEICIRGHQIMKGYLNDLEATAATIDQDGWLHSGDIGLVDDDDELFIVDRLKEIIKYKGFQVAPAELESLLISHSDINDVGVVGMKEEGVGEVPVAFVVRSNDSNISEDEIKQFVSKQVVFYKRINKVFFTDSIPKAPSGKILRKDLRAKLANGMIDELSLK
>maker-lg6-snap-gene-10.200-mRNA-1
MGKKRNRDKTFQIQIKVYKIVQEVKFGASEFCISRLPKGVMLTHNSQGTSHKRTLLNKSTVNIRICIFHSDDVILCVLLMFRIYALNSIMLCGLRVGAAILIMPSNK
>maker-lg6-snap-gene-10.199-mRNA-1
MAPQQEMMQKQSNEKSDVIFRSKLPDIYIPNHLSLHDYIFQNISDYASKPCLINGPTGHVYTYSDVHVTSRRIASGFQKLGVNRNDVVMILLPNCPEFVLSFLAASFLGVTATAANPFYTPAEIAKQAKGSNSKLVITESRYVEKIKDLGVPIVCTDDDESVPIPEGCLRFSELTQSTEIETVEISPDDVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEIHLLLELIQRCKITVAPIVPPIVLAIAKSPETEKYDLSSIRVVKSGAAPLGKELEDAVSAKFPNANLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILDPDTGDSLSRNQPGEICIRGHQIMKGYLNNPEATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHQDITDVAVIGMKDESAGEVPVAFVVKSKDSELSEDEVKQFVSKQVVFYKRINKVFFVDSIPKAPSGKILRKDLRAKLANGMIN
>maker-lg7-snap-gene-22.227-mRNA-1
MILMLLKLYYTINSTSSKLIFFHHTDRKMEKSGYGRDGIYRSLRPKLLLPKDPNTSLVSFLFRNSSSYSSKLALADSDSGHSFSFSDLNSAVSRLANGFLRLGIRKHDVVLIFAPNSYQFPLCFLAVTAIGAVFTTANPLYTVNEVSKQIKDSNPKIIITVEQLFDTIKGFDLPVVLLGSGEDSVQIHESNSKILSFDYVMNLSEPVSDLPLVDIKQSDTAALLYSSGTTGVSKGVELTHGNFIAASLMVTMDQDLLREYDSVFLCFLPMFHVFGLTVITYSQLQRGNAVISMAKFELEMVLKSIEKYRVTHLWVVPPVFLALTKQGNVKKYDLSSLKYLASGAAPLGKDLMEECGRNMPNLLLMQGYGMTETCGIVSLEDLRFGKRNTGSAGMLGPGIEAQVVSVETGKSQPPNQLGEIWVRGPNMMKGYLNNPKATKETIDSKGWVHTGDLGFFNEDGNLFVVDRIKELIKYKGFQVAPAELEDILVSHPEILDAAVIPFPDEEAGEVPIAFVVRSPNSSITEKDIQSFIAKQVAPYKRLRRVSFINSVPKSAAGKILRRELVQQVRSKM
MITAALHEPQIHKPADTSPADTSPPVSGDAVPPPTPRIFRSKLPDIDIPNHLPLHTYCFEKLSSVSDKPCLIVGSTGKSYSYGETHLICRRVAAGLHKMGIRKGDVIMILLQNSAEFVFSFMGASMIGAVSTTANPFYTSQEISKQLKSSGAKLIITQSQYVDKLRNLDDNTKIGQDLTVITTDGPPSENCLPFSTLTEDETDPPMESVHVDGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLNSNDVVLCVLPLFHIYSLNSVLLNSIRSGATVLLMHKFEIGALLDLIQRHRVTIAALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDNLRRHLPQAVLGQGYGMTEAGPVLSMSLGFAKEPIPTKSGSCGTVVRNAELKVVHLETRLSLGYNQPGEICIRGQQIMKEYLNDPEATSTTIDQEGWLHTGDIGYVDEDDEIFIIDRLKEVIKFKGFQVPPAELEALLINHHSIADAAVVPQNDELAGEVPVAFVVRSNGNEITEEDIKEYIAKQVVFYKRLHKVFFVPSIPKSPSGKILRKDLKAKLC
>maker-lg3-snap-gene-99.280-mRNA-1
MEYQKQDNEYIFRSLYPSVPIPDKLTLPEFVLQGVEEYTEKVAFVEAVTGKAVTYGDVVRDTERLAKALTSLGLRKGQVVVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGVITDATNFEKVKTLGLPVIVLGEEKIEGAVNWKDLLEAGDKCADNNKEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSSLFSVRSDMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRIFLNAMIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLTAFEAKFPNVQVQEAYGLTEHSCITLTHGDPERGQVNAKRNSVGFILPNLEVKFIDPDTGRSLPKNTSGELCVRSQCVMQGYFENKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPVACVVINPKAKEKEEDILNFVAANVANYKKVRAVHFVDSIPKSLSGKIMRRLLRDKIINMKKNELEK
>maker-lg4-snap-gene-82.236-mRNA-1
MVLQQQQQQQQTLLHTKKKKTTTDQQQEPPHDFIFRSKLPDISIPNHLPLIDYVFQNVSGDSTATCLIDGATGRIFSYADVLTNTRRIAAGIHRLGIRHRDVVMLLLPNSPEFALSFLAVAYLGAVSTTANPFYTQPEIEKQAKASAAKMIITKPCYVEKLANLQNDGVLIVCVEDDGDDAVSLPDGCVSFKELTRAEERELPKQEISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNVNLTGDDVILCFLPMFHIYALDALMLTAMRCGAALLIVPRFELNLVMELIQRYKVTVVPVAPPVVLAFVKSPETERYDLSSVKMMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPFETKSGACGTVIRNAEMKVVDTITGISLPRNKSGEICIRGDQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEVFIVDRLKELIKFKGYQVAPAELEALLISHPCINDAAVVPMKDEVADEVPVAFVVRTEGSKLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKDLRAKLETEYPK
>maker-lg4-snap-gene-82.238-mRNA-1
MSPQEPMITDQKQRDDVIFRSKLPDIYIPNHLPLHDYIFENISHFADKPCLINGPTGEVYSYADVHATSRKLAAGLRNLGVDKQDVVMLLLPNSPEFVFTFFAASFLGAITTAANPFFTTAEITKQAKASAVKIIITQSQYAGKIKNLQNDGVSIICTDDDSSSVEGCLPFSELSQLGEAEEQATEISPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYFHREDVILCVLPMFHIYALNSIMLCSLRVGATILIMPKFEISLLLEQIQRCKVTVAMVVPPIVLAMVKSPETEKYDLSLVRVIKSGAAPLGKELEDAVSTKFPNAKLGQGYGMTEAGPVLTMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGNSLPRNKPGEICIRGHQIMKGYLNDLEATAATIDQDGWLHSGDIGLVDDDDELFIVDRLKEIIKYKGFQVAPAELESLLISHSDINDVGVVGMKEEGVGEVPVAFVVRSNDSNISEDEIKQFVSKQVVFYKRINKVFFTDSIPKAPSGKILRKDLRAKLANGMIDELSLK
>maker-lg6-snap-gene-10.200-mRNA-1
MGKKRNRDKTFQIQIKVYKIVQEVKFGASEFCISRLPKGVMLTHNSQGTSHKRTLLNKSTVNIRICIFHSDDVILCVLLMFRIYALNSIMLCGLRVGAAILIMPSNK
>maker-lg6-snap-gene-10.199-mRNA-1
MAPQQEMMQKQSNEKSDVIFRSKLPDIYIPNHLSLHDYIFQNISDYASKPCLINGPTGHVYTYSDVHVTSRRIASGFQKLGVNRNDVVMILLPNCPEFVLSFLAASFLGVTATAANPFYTPAEIAKQAKGSNSKLVITESRYVEKIKDLGVPIVCTDDDESVPIPEGCLRFSELTQSTEIETVEISPDDVVALPFSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEIHLLLELIQRCKITVAPIVPPIVLAIAKSPETEKYDLSSIRVVKSGAAPLGKELEDAVSAKFPNANLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKILDPDTGDSLSRNQPGEICIRGHQIMKGYLNNPEATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIGHQDITDVAVIGMKDESAGEVPVAFVVKSKDSELSEDEVKQFVSKQVVFYKRINKVFFVDSIPKAPSGKILRKDLRAKLANGMIN
>maker-lg7-snap-gene-22.227-mRNA-1
MILMLLKLYYTINSTSSKLIFFHHTDRKMEKSGYGRDGIYRSLRPKLLLPKDPNTSLVSFLFRNSSSYSSKLALADSDSGHSFSFSDLNSAVSRLANGFLRLGIRKHDVVLIFAPNSYQFPLCFLAVTAIGAVFTTANPLYTVNEVSKQIKDSNPKIIITVEQLFDTIKGFDLPVVLLGSGEDSVQIHESNSKILSFDYVMNLSEPVSDLPLVDIKQSDTAALLYSSGTTGVSKGVELTHGNFIAASLMVTMDQDLLREYDSVFLCFLPMFHVFGLTVITYSQLQRGNAVISMAKFELEMVLKSIEKYRVTHLWVVPPVFLALTKQGNVKKYDLSSLKYLASGAAPLGKDLMEECGRNMPNLLLMQGYGMTETCGIVSLEDLRFGKRNTGSAGMLGPGIEAQVVSVETGKSQPPNQLGEIWVRGPNMMKGYLNNPKATKETIDSKGWVHTGDLGFFNEDGNLFVVDRIKELIKYKGFQVAPAELEDILVSHPEILDAAVIPFPDEEAGEVPIAFVVRSPNSSITEKDIQSFIAKQVAPYKRLRRVSFINSVPKSAAGKILRRELVQQVRSKM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University