Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Alnus glutinosa
Species name
Alnus glutinosa is a species of eudicot in the family Betulaceae (birch family).
Species info
Gene sequence info
Alnus_glutinosa.4CL.fa
Download
>Alngl2219S39751
MQVAPAELEAILLSHPSIEDAAVVPLPDEEAGEVPAASVVLTPGGNESEEDVINYVASNVAHYKKVRVVHFVDSIPKSPSGKIMRRLIREKMIENMRAH
>Alngl5680S32521
MEKSGYGRDGIYRSLRPPLVLPEDPNLSMVTFLFRNSSSYSHKPALIDADSSQILSFSQFKSTVARISRGFLRLGITKNDVVLIFAPNSIQFPLCFLGVVAIGAIATTANPVYTVHELARQVNDSNPKLIITVPELWDKVKNFNLPAVFLGSNHSSSSSSVIHFDALVRLGGTGSDFPESNVKQNDTAVLLYSSGTTGTSKGVILTHRNFIAASLMVAMDQELSGEAHNVFLCVLPMFHVFGMAVIVYSQLQIGNAVVSMGRFELEKLLRAVEKYRVSHLWVVPPIILALAKHSVVKKYDLSSLRHLGSGAAPLGKDLMEECARNIPQAAVVQGYGMTETCAIVSVENPRVGVRHTGSAGTLASGVESQIVSVDTLKPLPPNQLGEIWVRGPNMMQGYYNNAQATKLTIDKKGWVHTGDLGYFDGDGNLYVVDRIKELIKCKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVGYVVRSPNSSLTEEDVMKFIVNQVAPFKRLRRVTFINNVPKSAAGKILRRELIEKVRSKM
>Alngl11656S14307
MAIQAEQQEFIFRSKLPDIYIPKHLPIHSYCFENISKFGSRPCLINGSTGEVHTYYDVELTARKVASGLSKLGIRKGDVIMLLLPNSPEFAFVFLGASYLGAMTTAANPYFTAAEVSKQGKASNAKLVVTQSCYYDKVKDYAHENGVKIICIDDSPPKDCLHFSELTQADENDIPEVDISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVILCVLPLFHIYSLNSVFLCGLRAGAAILIVQKFEIASLLELIQKYKVSVMPIVPPIVLSITKFPDLHKYDLSSIKMLKSGGAPLGKEIEDTVKAKFPKALFGQGYGMTEAGPVLAMCLAFAKEPMEVKSGACGTVVRNAEMKIVDPDTGASLPRNQSGEICIRGDQIMKGYVNDPEATARTIDKEGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPNISDAAVVPMKDDLAGEVPVAFVVRSNGSQITEDEIKQFVSKQVVFYKRISRVFFIDVVPKSPSGKILRKELRAKLAAGFSN
>Alngl14811S16732
MGTNAQKLAEDDEHIFRSRFPAVPVPDITLPEFVLQDAESYAGKVAFVEPVTGKEVTYGDVVRDTRRFSKALRSLGLSKGGVVIVVLPNVAEYAIVALGIMAAGGVFSGANPAAHASEIKKQVEAAEAKLIVTNGPSYEKVKGLGLPAIILGEELIEGAMNWSKLLEAADRAGASSVKLDVHPTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVPPELVGQVTTLGLIPFFHIYGITGICCAMLRNKGKVVVMGRFELRTFLNALITQEVTFAPIVPPIILQLVKNPVVEEFDLSRLKLQAIMSAAAPLSPELLTAFENKFPGVHVQEAYGLTEHSCITLTLADPQTGSRLAKKSSVGFILPNLEVKFIDPDTGRSLPRNTPGEICVRSECVMQGYYNNKEETARTIDKQGWLHSGDIGFIDDEGNLFIVDRIKELIKYKGFQVAPAELEAILLSHPSIEDAAVVPLPDEEAGEVPAASVVLTPGGNESEEDVINYVASNVAHYKKVRVVHFVDSIPKSPSGKIMRRLIREKMIENMRAH
>Alngl35240S25191
MDKDGYTGDHGYFNEDGQLFVVDRIKKLIKCYGFQVAPAELEGLLLSHKEKLDAVLIPFPNTKASEVPIAYVVRSPNSLLTEDVQEFSAKQGNAIIESGRSFIEKLLVWSLALPN
>Alngl35240S25192
MSMITTTDQDRYDSFDDRLQKGNTVVLMGRVELEKVLGAVEKYRVTHVSVVPPVMILSAKHSALVRLVVVEADWFKCDAFGERCDGAVCKEYPSS
>Alngl62584S33607
MEPQKDLQEFIFRSKLPDIYIPNHLPLHTYCFENLSQFKDRPCLINGANGVTYTYSEVELTSRKVASGLDKVGIKQGEVIMLLLQNCPEFAFALLGASYIGAVSTTANPFFTPAEVAKQAKASNAKLIITQALYVDKVKDFAKENGVKVMCIDSQLDDFLHFSQLTQADENDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHGGLVTSVAQQVDGENPNLYFHSGDVILCVLPLFHIYSLNSVFLCGLRVGAAILIMQKFEIVKLLELVQQYKVTIAPFVPPIVLAIAKSPDAQWYDVSSIRMVMSGAAPMGKELEDDVRAKLPNAKLGQGYGMTEAGSVLTMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGASLPRNQAGEIYIRGSQIMKGIYIIPTYLH
>Alngl124360S14942
MVLLQNCAEFVFSFLGASMLGAVATTANPFYTSAEVFKQLNSSRAKLIITQSQNVDKLREPAGENFPKLGEDFTVITVDDPPEKCLHFSVISEANEDEFPTVSIEPDDPVALPFSSGTTGLPKGVVLTHKSLTTSVAQQVDGENPNLYLNPEDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPVVANFDLSSIRVVLSGAAPLGKELEEALRNRVPQAILGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLGRNQPGEICIRGSQIMKGYLNDAEATATTIDVEGWLHTGDIGYVDDDDEIFIVDRVKELIKFKGFQACIFSLSLYIDSLRKKLRDRLLSIDPLFPFTYFFIESLLTIIFYSCGQVPPAELEALLVSHPSIADAAVVPQKDDVAGEVPVAFVVRSNDFELTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAAASPVP
MQVAPAELEAILLSHPSIEDAAVVPLPDEEAGEVPAASVVLTPGGNESEEDVINYVASNVAHYKKVRVVHFVDSIPKSPSGKIMRRLIREKMIENMRAH
>Alngl5680S32521
MEKSGYGRDGIYRSLRPPLVLPEDPNLSMVTFLFRNSSSYSHKPALIDADSSQILSFSQFKSTVARISRGFLRLGITKNDVVLIFAPNSIQFPLCFLGVVAIGAIATTANPVYTVHELARQVNDSNPKLIITVPELWDKVKNFNLPAVFLGSNHSSSSSSVIHFDALVRLGGTGSDFPESNVKQNDTAVLLYSSGTTGTSKGVILTHRNFIAASLMVAMDQELSGEAHNVFLCVLPMFHVFGMAVIVYSQLQIGNAVVSMGRFELEKLLRAVEKYRVSHLWVVPPIILALAKHSVVKKYDLSSLRHLGSGAAPLGKDLMEECARNIPQAAVVQGYGMTETCAIVSVENPRVGVRHTGSAGTLASGVESQIVSVDTLKPLPPNQLGEIWVRGPNMMQGYYNNAQATKLTIDKKGWVHTGDLGYFDGDGNLYVVDRIKELIKCKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVGYVVRSPNSSLTEEDVMKFIVNQVAPFKRLRRVTFINNVPKSAAGKILRRELIEKVRSKM
>Alngl11656S14307
MAIQAEQQEFIFRSKLPDIYIPKHLPIHSYCFENISKFGSRPCLINGSTGEVHTYYDVELTARKVASGLSKLGIRKGDVIMLLLPNSPEFAFVFLGASYLGAMTTAANPYFTAAEVSKQGKASNAKLVVTQSCYYDKVKDYAHENGVKIICIDDSPPKDCLHFSELTQADENDIPEVDISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVILCVLPLFHIYSLNSVFLCGLRAGAAILIVQKFEIASLLELIQKYKVSVMPIVPPIVLSITKFPDLHKYDLSSIKMLKSGGAPLGKEIEDTVKAKFPKALFGQGYGMTEAGPVLAMCLAFAKEPMEVKSGACGTVVRNAEMKIVDPDTGASLPRNQSGEICIRGDQIMKGYVNDPEATARTIDKEGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPNISDAAVVPMKDDLAGEVPVAFVVRSNGSQITEDEIKQFVSKQVVFYKRISRVFFIDVVPKSPSGKILRKELRAKLAAGFSN
>Alngl14811S16732
MGTNAQKLAEDDEHIFRSRFPAVPVPDITLPEFVLQDAESYAGKVAFVEPVTGKEVTYGDVVRDTRRFSKALRSLGLSKGGVVIVVLPNVAEYAIVALGIMAAGGVFSGANPAAHASEIKKQVEAAEAKLIVTNGPSYEKVKGLGLPAIILGEELIEGAMNWSKLLEAADRAGASSVKLDVHPTDLCALPFSSGTTGLSKGVMLTHRNLVANLCSTLFSVPPELVGQVTTLGLIPFFHIYGITGICCAMLRNKGKVVVMGRFELRTFLNALITQEVTFAPIVPPIILQLVKNPVVEEFDLSRLKLQAIMSAAAPLSPELLTAFENKFPGVHVQEAYGLTEHSCITLTLADPQTGSRLAKKSSVGFILPNLEVKFIDPDTGRSLPRNTPGEICVRSECVMQGYYNNKEETARTIDKQGWLHSGDIGFIDDEGNLFIVDRIKELIKYKGFQVAPAELEAILLSHPSIEDAAVVPLPDEEAGEVPAASVVLTPGGNESEEDVINYVASNVAHYKKVRVVHFVDSIPKSPSGKIMRRLIREKMIENMRAH
>Alngl35240S25191
MDKDGYTGDHGYFNEDGQLFVVDRIKKLIKCYGFQVAPAELEGLLLSHKEKLDAVLIPFPNTKASEVPIAYVVRSPNSLLTEDVQEFSAKQGNAIIESGRSFIEKLLVWSLALPN
>Alngl35240S25192
MSMITTTDQDRYDSFDDRLQKGNTVVLMGRVELEKVLGAVEKYRVTHVSVVPPVMILSAKHSALVRLVVVEADWFKCDAFGERCDGAVCKEYPSS
>Alngl62584S33607
MEPQKDLQEFIFRSKLPDIYIPNHLPLHTYCFENLSQFKDRPCLINGANGVTYTYSEVELTSRKVASGLDKVGIKQGEVIMLLLQNCPEFAFALLGASYIGAVSTTANPFFTPAEVAKQAKASNAKLIITQALYVDKVKDFAKENGVKVMCIDSQLDDFLHFSQLTQADENDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHGGLVTSVAQQVDGENPNLYFHSGDVILCVLPLFHIYSLNSVFLCGLRVGAAILIMQKFEIVKLLELVQQYKVTIAPFVPPIVLAIAKSPDAQWYDVSSIRMVMSGAAPMGKELEDDVRAKLPNAKLGQGYGMTEAGSVLTMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGASLPRNQAGEIYIRGSQIMKGIYIIPTYLH
>Alngl124360S14942
MVLLQNCAEFVFSFLGASMLGAVATTANPFYTSAEVFKQLNSSRAKLIITQSQNVDKLREPAGENFPKLGEDFTVITVDDPPEKCLHFSVISEANEDEFPTVSIEPDDPVALPFSSGTTGLPKGVVLTHKSLTTSVAQQVDGENPNLYLNPEDVVLCVLPLFHIYSLNSVLLCSLRAGAAVLLMQKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPVVANFDLSSIRVVLSGAAPLGKELEEALRNRVPQAILGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGCSLGRNQPGEICIRGSQIMKGYLNDAEATATTIDVEGWLHTGDIGYVDDDDEIFIVDRVKELIKFKGFQACIFSLSLYIDSLRKKLRDRLLSIDPLFPFTYFFIESLLTIIFYSCGQVPPAELEALLVSHPSIADAAVVPQKDDVAGEVPVAFVVRSNDFELTEEAVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAAASPVP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University