Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Diptychocarpus strictus
Species name
Diptychocarpus strictus is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Diptychocarpus_strictus.CHS.fa
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>Distr.0001s273300.1.v2.1
MSNSGMNGISKQSSIVTRRVANPGKATVLALGKAFPSQVVPQENLVEGFLRDTKCEDSFIKEKLEHLCKTTTVKTRYTVLSREIIEKYPELTTEGTPTIKQRLEIANEAVVEMAFEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPTETESPFMELHYAVQQFLPGTQNVIDGRITEEGINFKLGRDLPQKIEDNIEEFCKKLMRKAGDDSMEFNDMFWTVHPGGPAILNRLEAKLKLEGEKLDCSRKALVDYGNVSSNTILYVMEYMRDELKKKGKAGKEWGLGLAFGPGITFEGLLIRSLT
>Distr.0002s136200.1.v2.1
MVMGSTSLDEIRKAQRADGPAGILGIGTANPANHVIQTEYPDYYFRITNSEHMTELKEKFQRMCDKSTIRKRHMYLTEEFLKENPNMCEYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWVAHPGGPAILDQVELKLGLKAEKMRATRHVLSEFGNMSSACVLFILDEMRKKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLRSVPL
>Distr.0010s77800.1.v2.1
MGPSLEEIRKAQRADGPACIMGIGTANPANQVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRYLHLTEEILKENPKMCAYMAPSLDARQDIVVAEVPKLGKEAAVRAIQEWGQPKSKITHVVFCTTSGIDMPGADYQLAKLLGLYPSVKRLMMYQQGCAAGGTVLRLAKDLAENNRGARVLVVCSEITTTLFRGPSDTHLDSLLGQVLFGDGAAALIVGSDPDTLVGEKPIFEVVSAGQTILPDSEGAIKLHLTEAGLTLHLVKYVPRLISNNIEKILEEAFKPLGINDWNSLFWIAHPGGRAILDELEIRLGLKTEKMRATRHVLSEYGNMVSACVLFILDEIRRKSAEDGATTTGEGFEWGVLFGFGPGLTVETIVLRSIPVDSSPLWTPTDQPTC
>Distr.0010s0800.1.v2.1
MEKQKETSTSTRRVANQGIATVLALGKAFPSNVVSQDNLVEEYLREIKCDDISIKDKLQHLCKTTTVKTRYTVMSKETMQKYPELATEGSPTIKQRLEIANEAVVAMAYEASLVCIKEWGRSVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGLSGLRIAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAALIIGADPRESESPFMELHYALQQFLPGTQGVIDGKLSEEGISFKLGRDLPQKIEDNVEEFCRKLMGKAGSSSLELNDLFWAVHPGGPAILNGMEKKLKLKPEKLECSRRALVDYGNVSSNTIFYIMEKVRDELEMKKWRGGGEEEWGLGLAFGPGVTFEGFLMRSLF
>Distr.0011s38300.1.v2.1
MSNRAVRNQPQRCTELSSRQDITFVEFSNLSRDGAVRAVREWGPSSEPRSKITHLVVSTPPRGVVPGSDIHLAMLLSLPGLIVHHESYSGDFDGSNVRGIFIRTYKRNRSPHVLIVCSEVTPARIPSQSRPSQERQLGTRVIDANRRSDAIVPHPIRTTDPPRPSQGRQTRLPSGVGNAHQPSETTIANRPSRGIITDRTNSASLPLGTIVASHLQRAIPSLEVTNLHVHIHVDTVNFHVREPAEGIRGGGTARRS
>Distr.0022s46400.1.v2.1
MGSIDAAVLGSEKKPNPGKATILAFGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILRKYPELAIEGQSTVTQRLDICNDAVTEMAVEASKACIKKWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFIGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPICEKPLFELHTAIQNFLPDTEKTIDGRLTEEGINFKLSRELPQIIEDNVENFCKKLIGKAGLAHKEYNEMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKLRNVNEAASEGEDNWGLILAFGPGVTFEGIVARNLDV
MSNSGMNGISKQSSIVTRRVANPGKATVLALGKAFPSQVVPQENLVEGFLRDTKCEDSFIKEKLEHLCKTTTVKTRYTVLSREIIEKYPELTTEGTPTIKQRLEIANEAVVEMAFEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPTETESPFMELHYAVQQFLPGTQNVIDGRITEEGINFKLGRDLPQKIEDNIEEFCKKLMRKAGDDSMEFNDMFWTVHPGGPAILNRLEAKLKLEGEKLDCSRKALVDYGNVSSNTILYVMEYMRDELKKKGKAGKEWGLGLAFGPGITFEGLLIRSLT
>Distr.0002s136200.1.v2.1
MVMGSTSLDEIRKAQRADGPAGILGIGTANPANHVIQTEYPDYYFRITNSEHMTELKEKFQRMCDKSTIRKRHMYLTEEFLKENPNMCEYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWVAHPGGPAILDQVELKLGLKAEKMRATRHVLSEFGNMSSACVLFILDEMRKKSAEDGVATTGEGLEWGVLFGFGPGLTVETVVLRSVPL
>Distr.0010s77800.1.v2.1
MGPSLEEIRKAQRADGPACIMGIGTANPANQVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRYLHLTEEILKENPKMCAYMAPSLDARQDIVVAEVPKLGKEAAVRAIQEWGQPKSKITHVVFCTTSGIDMPGADYQLAKLLGLYPSVKRLMMYQQGCAAGGTVLRLAKDLAENNRGARVLVVCSEITTTLFRGPSDTHLDSLLGQVLFGDGAAALIVGSDPDTLVGEKPIFEVVSAGQTILPDSEGAIKLHLTEAGLTLHLVKYVPRLISNNIEKILEEAFKPLGINDWNSLFWIAHPGGRAILDELEIRLGLKTEKMRATRHVLSEYGNMVSACVLFILDEIRRKSAEDGATTTGEGFEWGVLFGFGPGLTVETIVLRSIPVDSSPLWTPTDQPTC
>Distr.0010s0800.1.v2.1
MEKQKETSTSTRRVANQGIATVLALGKAFPSNVVSQDNLVEEYLREIKCDDISIKDKLQHLCKTTTVKTRYTVMSKETMQKYPELATEGSPTIKQRLEIANEAVVAMAYEASLVCIKEWGRSVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGLSGLRIAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAALIIGADPRESESPFMELHYALQQFLPGTQGVIDGKLSEEGISFKLGRDLPQKIEDNVEEFCRKLMGKAGSSSLELNDLFWAVHPGGPAILNGMEKKLKLKPEKLECSRRALVDYGNVSSNTIFYIMEKVRDELEMKKWRGGGEEEWGLGLAFGPGVTFEGFLMRSLF
>Distr.0011s38300.1.v2.1
MSNRAVRNQPQRCTELSSRQDITFVEFSNLSRDGAVRAVREWGPSSEPRSKITHLVVSTPPRGVVPGSDIHLAMLLSLPGLIVHHESYSGDFDGSNVRGIFIRTYKRNRSPHVLIVCSEVTPARIPSQSRPSQERQLGTRVIDANRRSDAIVPHPIRTTDPPRPSQGRQTRLPSGVGNAHQPSETTIANRPSRGIITDRTNSASLPLGTIVASHLQRAIPSLEVTNLHVHIHVDTVNFHVREPAEGIRGGGTARRS
>Distr.0022s46400.1.v2.1
MGSIDAAVLGSEKKPNPGKATILAFGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILRKYPELAIEGQSTVTQRLDICNDAVTEMAVEASKACIKKWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFIGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPICEKPLFELHTAIQNFLPDTEKTIDGRLTEEGINFKLSRELPQIIEDNVENFCKKLIGKAGLAHKEYNEMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKLRNVNEAASEGEDNWGLILAFGPGVTFEGIVARNLDV
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University