Enzyme
The enzyme participates in the flavonoid biosynthesis pathway found in plants. It catalyses the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins. While the enzyme from the legume Medicago truncatula (MtANR) can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana (AtANR) uses only NADPH. Also, while the substrate preference of MtANR is cyanidin>pelargonidin>delphinidin, the reverse preference is found with AtANR. cf. EC 1.3.1.112, anthocyanidin reductase [(2S)-flavan-3-ol-forming].
ANR
Enzyme
Anthocyanidin reductase
Enzyme name
EC:1.3.1.77
Entry
Oxidoreductases;Acting on the CH-CH group of donors;With NAD+ or NADP+ as acceptor
Class
(2R,3R)-flavan-3-ol:NAD(P)+ 3,4-oxidoreductase
Sysname
a (2R,3R)-flavan-3-ol + 2 NAD(P)+ = an anthocyanidin with a 3-hydroxy group + 2 NAD(P)H + H+ [RN:R07351 R07352]
Reaction
anthocyanidin with a 3-hydroxy group [CPD:C21381];NADH [CPD:C00004];NADPH [CPD:C00005];H+ [CPD:C00080]
Product
Species information
Dichanthelium oligosanthes
Species name
Dichanthelium oligosanthes is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Dichanthelium_oligosanthes.ANR.fa
Download
>rna-gnl|WGS:LWDX|Do013672.1_mrna
MSPVLRVTGGGGFIGSWLVRKLLDRGCVVHATMRSLEDEKKAGLLRSLPGAAERLRLFQANMYDADSFEPAIAGCEFVFLIATPLVHDPTSTKYKNTTEATVDAVRIILRQCERSGTVKRVIHTASVTAASPLREDGTGYKDFTNESCWTPLNLSYGFSNVHLDVRIRVVQVAVGEGAAELQVYNESTEPRALEVVTLTCGLVGGDTIQPYLCSSIPVIVSPLTGHAVHHNSLLFMQALLGSVPVAHVEDVCEAHAFCMDQPSMAGRFLCAAGYPNMRDLLDRFVSKYPEIKIQLEQVTGDGVRVRADTTKLEDLGFRNRYGVEETLDCSVECAKRLGEL
>rna-gnl|WGS:LWDX|Do008534.1_mrna
MTSSTDHPQEYILSKLVSEEELLAYNTGESPAFEVVTVPCPAVAGDTLQGRTTESLESAASPVTRDAGRFGALRMLQRLMGSVPLAHVDDVCGALVFCEEQPSMAGRFICGAAYPTVTDIVDHFATKIELGLPSVQAHSEKLGFRYKYGMEEILDGSIDCAVRFARLDASKLIVQG
>rna-gnl|WGS:LWDX|Do027830.1_mrna
MEKNSHLKDLQALGSLEIFRADLDEEGSFDDAVADCDYAFLVAAPVNIHTKDPEVHRRHSTLYCNFSFVKHLVMASTLFIPIAWWQKELVEPAVRGTLNVMRSCVRAGTVKRVVLTSSAAAVSSRPLQGDGHVLDEDSWSDVEYLTANKSGPWGYPVSKVPLEKEACRFAEEHGISLVTVCPVITVGAAPAPSARTSVPNCLSLLSGDKAEFAVLDAIERATGCVPLVHVDDLCRAELFVAEEEAAAAGRYICCSLNTTIAELARFLADKYPQYGVKTHLLSGERLEKPRVCLSSAKLVREGFEFKYRTLDGIYDDMVEYGKAMGILPN
>rna-gnl|WGS:LWDX|Do025148.1_mrna
MAQPPPETLSLAGRRVAFTTPQTGAGGYGGRLGALLRQRGAHPVPAPTIAVQPHDPDRLGPLLLPGALDPFAAIAFTSRSGISAFARALPTSSHHRPLSDSALPFTVAALGSDADLLDRAFLDRLCGGGDAGARVVTVLVPDVPTPAGLVEALGRGSGRRVLCPVPDVVGLREPPVVPDFLAGLEAAGWVPVRAPAYTTCWAGPGCAGPLVDPDAAAPDAVVFTSTAEVEGLLKGLDAAGWSWEGLRARWPGMVVAAHGPVTAGGARSLGVEVDVEETLVPAVKGTLNVLKSCKKNPFLKRVVLTSSSSAVDLKIVPSLLFSSKAMVWPGEASDVLGLFQGDTARFSCYGRMGYVHIDDVASSHILLYETPEATGRYLCSSVVLDNDELVSFLAKRYPIFPIPRRLDNPYGKQTYQLNTSKLEGLGFKFRGVQEMFDDCVQSLKDQGHLLECPL
>rna-gnl|WGS:LWDX|Do027716.1_mrna
MGSVGGGSPEEQQAGGSDPPVVCVTGSTGYVGSWLVRTLLRRGYRVHATARDTGTARAWLIAAISTCLPGVELTMAEVPCRPLFVSSGKAWQVFAAVEGGDRLRVFRADMGEDGSFDAAVTGCVAIFHVAASMELQVAPGHDNVGEFMRFLDLTSTLALTRSHLCYPWLTDVEEERVRSDVLEPATRGTINVLQSCVRAGTVRRVIFTSSVSTLTAADVEGRRKAVVDESCLRDLDDVWRTKPVGWIYILSKRLTEEAAFRFARENGLHLVSVILPTVAGPFLTPSVPTSIQLLLSPITGAPTLYSLLASVHSRFGCLPLAHVQDACDAHVFLAESPRAEGRYLCAAGGHPMAQVARLLASRYPPFKPAERHVREPSPPRSLDFFRLSRDFDASCSSTVSSKRLLDLGFRFEYGVGDIVTDSVGQCLDHGFLEHPES
>rna-gnl|WGS:LWDX|Do009354.1_mrna
MPAVTAKGTVVTEWCMAASVPCISPSPSGSFEPDSFEHEEQQRRSAGVRHRRRRVHRLLAHEQAPRERLMPPSGTSVRPNAQLITQLATHFALTWESYPSSENLIAGDEEKAGLLRRLVSGAVESGRLVLFKADLYAAATFAPAIAGCRFVFLVAMPFQHDPTSTKYKSTAEAALDAARVILRQCAGSKTVKRVIRTGTMATCSPFREDSNGFKDAMDESCWTPLDADYPLRNAQFHVRSGGPAENFSFPRKQGKAASYDV
>rna-gnl|WGS:LWDX|Do009353.1_mrna
LTSMEERKSSGNGVRVCVTGGAGFIGSWLVKKLLERGYTVHATLRDIGDEEKTGLLRRLVPGAAESGRLVLFDADLYDAATFAPAIAGCEFVFLVATPLRHDATSTKYKSTAEAARDAARMILRQCADSSTVKRVIHTGSMAACSPLKEDSTGFKDAVDESCWTPLNVDYPLRNAEYDEYILSKLVSEKELLAYNAGESPAFEVVTVPCSVVAGDTLQSHTTLSLEGVASPVTRDERHLAGLTMLQQLLGSVPLTHVDDVCDALVFCMERPSMAGRFLCAAAYPTFADIVEHFADKYPHLDILKGSEVLPSVQVHSDKLGELGFRRGTRTHADTMHHSVATVPLAVTAGMLYARLGAASIRLGMHRLFAFAPVLALLVVLPFFVPLHGIRCLAAFFLVWLGEFKLLLLAFSRGPLDPXLRPLPFVFTAALPVKLRQRQADAAAVTKAIALPLLSSGIKVAVMASVFYLLFRSKETMHPYAVFTLYGIIIYCILDSVLPCLAVMGSALGMEMEPQFDKPYFSASLGDFWGRRWNLMVXAVLRPSVYDPVRXXXXXXXXVXATFLVSALMHEVMVYYLTFRAPTGTVTAFFALHGACVCAERWYARRCCRRPPRAVATPLVVGFVAGTAFWLFFPALFGDGMDDLYLAEQTHSEAAMAEERRSSGVRVCVTGGAGFIGSWLVKKLLEKGYTVHATLRNTGDEEKAGLLRRLVHGAAERLRLFDADLFDAATFAPAIAGCQFVFLLATPFGLEAAGSKYKSTAEAVVDAVRAILRLCEESKTVKRVIHTASVSAASPLKEKGSGDGYKDFISESCWTPLDVDYPLRSAHFDKYILSKLQSEQELLSYNAGESPGFEVVTLPLGLVAGDTVLSRVPETLESAVSPVSGNEECFGLPRILQQLLGSLPLVHVDDVCDALVFCMERPSIAGRFLCAAAYPTIHDVAGHYANKFPHLDILRETEAVSRVQPEGDKLAELGFRYKYGMEEILDSSVACAARLASPSVPPHQVITIQQSPSMAEEGKSSSGVRVCVTGGAGFIGSWLVKKLLEKGYTVHATLRNTGDEEKAGLLRRLVPGAVDRLRLFEADLFDAATFAPAIAGCRFVFLVATPYGLEAACSKFKSTAEAAVAAVRAILRQCEVSKTVKRLIHTASISAASPLKEADAGAGYKDFISESCWTPLNVDYPLRSEHLDKYILSKLQSEQELLSYNAGESPAFEVVTLSLGLVAGDTVLGRVPETLEHAVSPVSRDEPGFALLRLLQSLLGSVPLVHVDDACDALVFCMERPSIAGRFLCAAAYPTIHDVAGHFANKFPHLDVLNETEAAARVEPAEDKLGELGFRYKYGVEEILDASVACAARLGCLDAAKLSMQKG
>rna-gnl|WGS:LWDX|Do015174.1_mrna
LHCTPEERRSPAISSTGNKMKTACVTGGSGYIASALIKMLLEKGYAVKTTVRNPGLMILSHPSFRFGPAGAWPPGGPPYRADLDVEGSFDDAIAGCDYAFLVAAPVNLSAGEDPEKELIEPAVRGTLNVMRSCVKAGTVRRVILTSSASAVYIRPELQGDGHVLDEDSWSDVEYLRAEKPPTWGYCVSKVLVEEAACRFAQEHGVSLVTVCPVITVGAAPSVTMNTSVPNCLSLLSGDEVWLSVLKAIERTSGSVPLSHVDDLCCAELFVAEEEAAAGRYICCSLSTTVAELARFLAQKYPQYDVKRNLHTDEQLLEKPRACLSSAKLVREGFEFKHSTLDEIYDNVVDPRKLISSIIITSSSSGCWPAVTSSIDDSTRQRWWPAMSAGEKKKTACVTGGNGYIASALIKMLLEEGYAVKTTVRNPDDMEKNSHLKGLQELGPLTVLRADLDEEGSFDDAVAGCDYAFLVAAPVNLAAEDPEKEQIEPSVRGTLNVMRSCVKAGAVRRVILTSSAGGVYIRPELQGDGHVLDEESWSDVEYLTANKPPTWGYCVSKVLLEKEACRFAEEHGISLVTVCPVITVGPAPATKVRTSIVDILSLLSGNEAGLGVLKGIEKTSGAVQLVHVGDLCRAELFVAEEETAAGRYICCGLNTTIVELARFLAQKYPQYGVKTDL
>rna-gnl|WGS:LWDX|Do017509.1_mrna
MLVTGASGFIGSTLVRGLLDRGYNIRAGVLNPGQSMTRRRRTTSSRWPPAPERAASASSVATSSTAPRSSTPRGDARASSTSPPPAPSTPSRTPRHVLRRSAVALSPPARSPRRPALLCLLLQNQLMVPAVEGTLNVLRAAKAAGTVRRVVVTSSISAIVPSPGWPAGEVRDERCWTDIDYCEKNGAPQGYPTWAGESGGRGEEAHGARAADHPHGEDHQGCRGEPQEQRAHLLMDDKAETDHLLALAAGAGVEGRLRIFRCNLFDGAALLDAARGCSGVFHLASPCIIYAVSDPQKQLIVPAVEGTLNVLRAAKEAGSVRRVAVTSSISSIQVSMFPKDTQPGLVRAEVGAKKLVALGLQFSPLEKIIRDAVESLQSRGYIS
>rna-gnl|WGS:LWDX|Do001812.1_mrna
MASAGDSGGAASRDLVCVTGGSGFIGSWLVRLLLDRGYTVHGTVKNITLYPVAQVDKSFLGSLILLFQNELLEPAVKGTLNVLRTAKDCGVGRVVLMSSQAAMVPNPNWPADKVIDDDSWADVELLKKVQFWYSVSKTLAEKAAWDFAAKEGLRMAVLNPGM
MSPVLRVTGGGGFIGSWLVRKLLDRGCVVHATMRSLEDEKKAGLLRSLPGAAERLRLFQANMYDADSFEPAIAGCEFVFLIATPLVHDPTSTKYKNTTEATVDAVRIILRQCERSGTVKRVIHTASVTAASPLREDGTGYKDFTNESCWTPLNLSYGFSNVHLDVRIRVVQVAVGEGAAELQVYNESTEPRALEVVTLTCGLVGGDTIQPYLCSSIPVIVSPLTGHAVHHNSLLFMQALLGSVPVAHVEDVCEAHAFCMDQPSMAGRFLCAAGYPNMRDLLDRFVSKYPEIKIQLEQVTGDGVRVRADTTKLEDLGFRNRYGVEETLDCSVECAKRLGEL
>rna-gnl|WGS:LWDX|Do008534.1_mrna
MTSSTDHPQEYILSKLVSEEELLAYNTGESPAFEVVTVPCPAVAGDTLQGRTTESLESAASPVTRDAGRFGALRMLQRLMGSVPLAHVDDVCGALVFCEEQPSMAGRFICGAAYPTVTDIVDHFATKIELGLPSVQAHSEKLGFRYKYGMEEILDGSIDCAVRFARLDASKLIVQG
>rna-gnl|WGS:LWDX|Do027830.1_mrna
MEKNSHLKDLQALGSLEIFRADLDEEGSFDDAVADCDYAFLVAAPVNIHTKDPEVHRRHSTLYCNFSFVKHLVMASTLFIPIAWWQKELVEPAVRGTLNVMRSCVRAGTVKRVVLTSSAAAVSSRPLQGDGHVLDEDSWSDVEYLTANKSGPWGYPVSKVPLEKEACRFAEEHGISLVTVCPVITVGAAPAPSARTSVPNCLSLLSGDKAEFAVLDAIERATGCVPLVHVDDLCRAELFVAEEEAAAAGRYICCSLNTTIAELARFLADKYPQYGVKTHLLSGERLEKPRVCLSSAKLVREGFEFKYRTLDGIYDDMVEYGKAMGILPN
>rna-gnl|WGS:LWDX|Do025148.1_mrna
MAQPPPETLSLAGRRVAFTTPQTGAGGYGGRLGALLRQRGAHPVPAPTIAVQPHDPDRLGPLLLPGALDPFAAIAFTSRSGISAFARALPTSSHHRPLSDSALPFTVAALGSDADLLDRAFLDRLCGGGDAGARVVTVLVPDVPTPAGLVEALGRGSGRRVLCPVPDVVGLREPPVVPDFLAGLEAAGWVPVRAPAYTTCWAGPGCAGPLVDPDAAAPDAVVFTSTAEVEGLLKGLDAAGWSWEGLRARWPGMVVAAHGPVTAGGARSLGVEVDVEETLVPAVKGTLNVLKSCKKNPFLKRVVLTSSSSAVDLKIVPSLLFSSKAMVWPGEASDVLGLFQGDTARFSCYGRMGYVHIDDVASSHILLYETPEATGRYLCSSVVLDNDELVSFLAKRYPIFPIPRRLDNPYGKQTYQLNTSKLEGLGFKFRGVQEMFDDCVQSLKDQGHLLECPL
>rna-gnl|WGS:LWDX|Do027716.1_mrna
MGSVGGGSPEEQQAGGSDPPVVCVTGSTGYVGSWLVRTLLRRGYRVHATARDTGTARAWLIAAISTCLPGVELTMAEVPCRPLFVSSGKAWQVFAAVEGGDRLRVFRADMGEDGSFDAAVTGCVAIFHVAASMELQVAPGHDNVGEFMRFLDLTSTLALTRSHLCYPWLTDVEEERVRSDVLEPATRGTINVLQSCVRAGTVRRVIFTSSVSTLTAADVEGRRKAVVDESCLRDLDDVWRTKPVGWIYILSKRLTEEAAFRFARENGLHLVSVILPTVAGPFLTPSVPTSIQLLLSPITGAPTLYSLLASVHSRFGCLPLAHVQDACDAHVFLAESPRAEGRYLCAAGGHPMAQVARLLASRYPPFKPAERHVREPSPPRSLDFFRLSRDFDASCSSTVSSKRLLDLGFRFEYGVGDIVTDSVGQCLDHGFLEHPES
>rna-gnl|WGS:LWDX|Do009354.1_mrna
MPAVTAKGTVVTEWCMAASVPCISPSPSGSFEPDSFEHEEQQRRSAGVRHRRRRVHRLLAHEQAPRERLMPPSGTSVRPNAQLITQLATHFALTWESYPSSENLIAGDEEKAGLLRRLVSGAVESGRLVLFKADLYAAATFAPAIAGCRFVFLVAMPFQHDPTSTKYKSTAEAALDAARVILRQCAGSKTVKRVIRTGTMATCSPFREDSNGFKDAMDESCWTPLDADYPLRNAQFHVRSGGPAENFSFPRKQGKAASYDV
>rna-gnl|WGS:LWDX|Do009353.1_mrna
LTSMEERKSSGNGVRVCVTGGAGFIGSWLVKKLLERGYTVHATLRDIGDEEKTGLLRRLVPGAAESGRLVLFDADLYDAATFAPAIAGCEFVFLVATPLRHDATSTKYKSTAEAARDAARMILRQCADSSTVKRVIHTGSMAACSPLKEDSTGFKDAVDESCWTPLNVDYPLRNAEYDEYILSKLVSEKELLAYNAGESPAFEVVTVPCSVVAGDTLQSHTTLSLEGVASPVTRDERHLAGLTMLQQLLGSVPLTHVDDVCDALVFCMERPSMAGRFLCAAAYPTFADIVEHFADKYPHLDILKGSEVLPSVQVHSDKLGELGFRRGTRTHADTMHHSVATVPLAVTAGMLYARLGAASIRLGMHRLFAFAPVLALLVVLPFFVPLHGIRCLAAFFLVWLGEFKLLLLAFSRGPLDPXLRPLPFVFTAALPVKLRQRQADAAAVTKAIALPLLSSGIKVAVMASVFYLLFRSKETMHPYAVFTLYGIIIYCILDSVLPCLAVMGSALGMEMEPQFDKPYFSASLGDFWGRRWNLMVXAVLRPSVYDPVRXXXXXXXXVXATFLVSALMHEVMVYYLTFRAPTGTVTAFFALHGACVCAERWYARRCCRRPPRAVATPLVVGFVAGTAFWLFFPALFGDGMDDLYLAEQTHSEAAMAEERRSSGVRVCVTGGAGFIGSWLVKKLLEKGYTVHATLRNTGDEEKAGLLRRLVHGAAERLRLFDADLFDAATFAPAIAGCQFVFLLATPFGLEAAGSKYKSTAEAVVDAVRAILRLCEESKTVKRVIHTASVSAASPLKEKGSGDGYKDFISESCWTPLDVDYPLRSAHFDKYILSKLQSEQELLSYNAGESPGFEVVTLPLGLVAGDTVLSRVPETLESAVSPVSGNEECFGLPRILQQLLGSLPLVHVDDVCDALVFCMERPSIAGRFLCAAAYPTIHDVAGHYANKFPHLDILRETEAVSRVQPEGDKLAELGFRYKYGMEEILDSSVACAARLASPSVPPHQVITIQQSPSMAEEGKSSSGVRVCVTGGAGFIGSWLVKKLLEKGYTVHATLRNTGDEEKAGLLRRLVPGAVDRLRLFEADLFDAATFAPAIAGCRFVFLVATPYGLEAACSKFKSTAEAAVAAVRAILRQCEVSKTVKRLIHTASISAASPLKEADAGAGYKDFISESCWTPLNVDYPLRSEHLDKYILSKLQSEQELLSYNAGESPAFEVVTLSLGLVAGDTVLGRVPETLEHAVSPVSRDEPGFALLRLLQSLLGSVPLVHVDDACDALVFCMERPSIAGRFLCAAAYPTIHDVAGHFANKFPHLDVLNETEAAARVEPAEDKLGELGFRYKYGVEEILDASVACAARLGCLDAAKLSMQKG
>rna-gnl|WGS:LWDX|Do015174.1_mrna
LHCTPEERRSPAISSTGNKMKTACVTGGSGYIASALIKMLLEKGYAVKTTVRNPGLMILSHPSFRFGPAGAWPPGGPPYRADLDVEGSFDDAIAGCDYAFLVAAPVNLSAGEDPEKELIEPAVRGTLNVMRSCVKAGTVRRVILTSSASAVYIRPELQGDGHVLDEDSWSDVEYLRAEKPPTWGYCVSKVLVEEAACRFAQEHGVSLVTVCPVITVGAAPSVTMNTSVPNCLSLLSGDEVWLSVLKAIERTSGSVPLSHVDDLCCAELFVAEEEAAAGRYICCSLSTTVAELARFLAQKYPQYDVKRNLHTDEQLLEKPRACLSSAKLVREGFEFKHSTLDEIYDNVVDPRKLISSIIITSSSSGCWPAVTSSIDDSTRQRWWPAMSAGEKKKTACVTGGNGYIASALIKMLLEEGYAVKTTVRNPDDMEKNSHLKGLQELGPLTVLRADLDEEGSFDDAVAGCDYAFLVAAPVNLAAEDPEKEQIEPSVRGTLNVMRSCVKAGAVRRVILTSSAGGVYIRPELQGDGHVLDEESWSDVEYLTANKPPTWGYCVSKVLLEKEACRFAEEHGISLVTVCPVITVGPAPATKVRTSIVDILSLLSGNEAGLGVLKGIEKTSGAVQLVHVGDLCRAELFVAEEETAAGRYICCGLNTTIVELARFLAQKYPQYGVKTDL
>rna-gnl|WGS:LWDX|Do017509.1_mrna
MLVTGASGFIGSTLVRGLLDRGYNIRAGVLNPGQSMTRRRRTTSSRWPPAPERAASASSVATSSTAPRSSTPRGDARASSTSPPPAPSTPSRTPRHVLRRSAVALSPPARSPRRPALLCLLLQNQLMVPAVEGTLNVLRAAKAAGTVRRVVVTSSISAIVPSPGWPAGEVRDERCWTDIDYCEKNGAPQGYPTWAGESGGRGEEAHGARAADHPHGEDHQGCRGEPQEQRAHLLMDDKAETDHLLALAAGAGVEGRLRIFRCNLFDGAALLDAARGCSGVFHLASPCIIYAVSDPQKQLIVPAVEGTLNVLRAAKEAGSVRRVAVTSSISSIQVSMFPKDTQPGLVRAEVGAKKLVALGLQFSPLEKIIRDAVESLQSRGYIS
>rna-gnl|WGS:LWDX|Do001812.1_mrna
MASAGDSGGAASRDLVCVTGGSGFIGSWLVRLLLDRGYTVHGTVKNITLYPVAQVDKSFLGSLILLFQNELLEPAVKGTLNVLRTAKDCGVGRVVLMSSQAAMVPNPNWPADKVIDDDSWADVELLKKVQFWYSVSKTLAEKAAWDFAAKEGLRMAVLNPGM
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University