Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Dichanthelium oligosanthes
Species name
Dichanthelium oligosanthes is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Dichanthelium_oligosanthes.CHS.fa
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>rna-gnl|WGS:LWDX|Do009361.1_mrna
MAGATVTVEEVRKAQRASGPATVLAIGTATPANCVYQADYPDYYFRVTKSEHLTDLKEKFKRMCDKSMIRKRYMHLTEDILQENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAVIVGADPDERVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEEAFKPLGINDWNSIFWVAHPGGPAILDQVEAKVSLDKERMRATRHVLSEYGNMSSACVLFILDEMRKRSAEDGQATTGEGFDWGVLFGFGPGLTVETVVLHSVPITAGAAA
>rna-gnl|WGS:LWDX|Do024365.1_mrna
MLYQAGCHGGGIALRLAKDLAENNPGARVLVVCSEVITMAMRGPSETHMGNLVGQAIFGDAAGAAIVGADLTGLEHPLFEMVSAAQGINQGRRRRWSPSCTRRG
>rna-gnl|WGS:LWDX|Do028449.1_mrna
MLSSYHALVASQLQNYLVHKTMVSNTTANKQGSSMAPNPGKATILALGHAFPQQLVMQDYVVDGFMKNTNCDDPELKEKLTRLCKTTTVKTRYVVMSEEILKNYPELAQEGLPTMKQRLDISNKAVTQMATEASLACVQSWGGALSSITHLVYVSSSEARFPGGDLHLARALGLSPDVRRVMLAFTGCSGGVAGLRVAKGLAESCPGARVLLATSETTVVGFRPPSPDRPYDLVGVALFGDGAGAAVIGTDPAPAERPLFELHSALQSFLPGTEKTIEGRLTEEGIKFQLGRELPHIIEAHVEDFCRRLMKEREDGGERMGYDDMFWAVHPGGPAILTKMEGRLGLGGDKLRASRCALRDFGNASSNTIVYVLENMVEETRRRKAAAEEEAGDGEDCEWGLILAFGPGITFEGILARNLQATARLK
>rna-gnl|WGS:LWDX|Do030105.1_mrna
LNARQDILVEEVPKLGAAAAEKAIAEWGQSRSRITHLVFCTTSGVDMPGADSQLIKLLGLRPSVKRVMLYHQGCFAGGMVLRIAKDLAENNRGARVLIVCSEITVVTFRGPSESHLDSLVGQALFGDGAAAVIVGADPDERVERPWFQLVSAGETILPDSDGAIEGHLREVGLTFHLQERVPELISANIERLLEESFKPLGISDWNSIFWVAHPGGPAILNSVEAKAGLEKARLRATRHVLSEYGNMSSACVLFILDEMRKFSAEDGRTTTGEGMDWGVLFGFGPGLTVETIVLHSVRIANGRAA
>rna-gnl|WGS:LWDX|Do020464.1_mrna
MGIGKAVPSHEFQQKSFSDYYFEITSSNHMVDLKAKFANICEKTMIEKRHFYMSNEMLRDSPSITAYSSTSLTRRQELADVGVPELGAKAARKAICDWGKQASDITHLVASTSSSGCMPGADCELARLLGLKPSTKRFMLYQTGCHGGCMALSLSKDLAENNPGARVLVVCSEVCTLSLRGPSESHIGDLVGQAILGDAAGAVVVGSSPAADEHTIFELVLTCQETIPGTEEALVSKLREEGILYSLHRDIPLHVSSSIERLVELMLKETMAPVPDLNEEVFWVVHPGGRGILDWIEGKLGLREEKLAASRSVMRQYGNTRCSSVILVMEEMRRRSEQHGLRTAGEGLDWGLLVGYGPGITVEAILLTALPDKAII
>rna-gnl|WGS:LWDX|Do024559.1_mrna
LLEEVPKLGAAAGEKAIREWGQQRSRIKHLIFCTTSGVDMLGADYQLTKLLGLCPSMMNRVRLYHQGCFAGGMVLRVARDLAENNCGARVLIVCSEITVVTFRGLFKSHHYYKTGHQCRYISTGLI
>rna-gnl|WGS:LWDX|Do003568.1_mrna
MAFIGDGASAVVVGADSVAAAGEEEAEKPLFEIVRSKQLTLPGTSDAMRGLIREMGMTVDIVREVPSLFAGNVEAALRGLLGGPGGGLVGDVVGGDWNKMFWSMHYPGGRLVLDKVEAALGLDPAKMRASRARCSPSSTRDPNASRVPSEVAMKFITETN
>rna-gnl|WGS:LWDX|Do003826.1_mrna
MGSSAPATVVSEIRRAHQRADGSAAVLGIGTATPPNCVPQDGYVDYYFRVTNSDHLTDLKAKLDRICNKSGIKQRFIHLTEEIVAANPDFTDRASPSLDAPVDITFAAVPELAESAAAKVIAEWGRPATEITHLVFSTGSAGVTPENQPHGLPHHAQPPRLRRRGQVAPARQGYRREQRGARVLVACSEVTLIAFYGPGDGCLDHILGQALFGDGDGDGAVIVPRLLGSNVERCLIDALDELGVSARWNDLFWAIHHGGRAILDRIEGVLGLDESELAASRHVLSEFGNMSSTTVIYVLDELRRRRAAKQDGGEAPEWGVMMAFRPGITIETMVLRAPAASLMEGN
>rna-gnl|WGS:LWDX|Do026613.1_mrna
MSDELLRSNPSITAYKSPSVTLRQELADEEVPSTTGAAKQASDITHLVFCASSTGCLPGADWELVQLLGLPPATKRVMLSPSKDLAENNPGARVLVVCSKVIPLSLRGPSESHVGQAIFGDAAGAVVVGSDPDPGAGERGVFELVWTSQEIVPGTRDGWCSPCTGTCRSTCPAPDVNGEVF
MAGATVTVEEVRKAQRASGPATVLAIGTATPANCVYQADYPDYYFRVTKSEHLTDLKEKFKRMCDKSMIRKRYMHLTEDILQENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPRSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAVIVGADPDERVERPLFQLVSASQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIERALEEAFKPLGINDWNSIFWVAHPGGPAILDQVEAKVSLDKERMRATRHVLSEYGNMSSACVLFILDEMRKRSAEDGQATTGEGFDWGVLFGFGPGLTVETVVLHSVPITAGAAA
>rna-gnl|WGS:LWDX|Do024365.1_mrna
MLYQAGCHGGGIALRLAKDLAENNPGARVLVVCSEVITMAMRGPSETHMGNLVGQAIFGDAAGAAIVGADLTGLEHPLFEMVSAAQGINQGRRRRWSPSCTRRG
>rna-gnl|WGS:LWDX|Do028449.1_mrna
MLSSYHALVASQLQNYLVHKTMVSNTTANKQGSSMAPNPGKATILALGHAFPQQLVMQDYVVDGFMKNTNCDDPELKEKLTRLCKTTTVKTRYVVMSEEILKNYPELAQEGLPTMKQRLDISNKAVTQMATEASLACVQSWGGALSSITHLVYVSSSEARFPGGDLHLARALGLSPDVRRVMLAFTGCSGGVAGLRVAKGLAESCPGARVLLATSETTVVGFRPPSPDRPYDLVGVALFGDGAGAAVIGTDPAPAERPLFELHSALQSFLPGTEKTIEGRLTEEGIKFQLGRELPHIIEAHVEDFCRRLMKEREDGGERMGYDDMFWAVHPGGPAILTKMEGRLGLGGDKLRASRCALRDFGNASSNTIVYVLENMVEETRRRKAAAEEEAGDGEDCEWGLILAFGPGITFEGILARNLQATARLK
>rna-gnl|WGS:LWDX|Do030105.1_mrna
LNARQDILVEEVPKLGAAAAEKAIAEWGQSRSRITHLVFCTTSGVDMPGADSQLIKLLGLRPSVKRVMLYHQGCFAGGMVLRIAKDLAENNRGARVLIVCSEITVVTFRGPSESHLDSLVGQALFGDGAAAVIVGADPDERVERPWFQLVSAGETILPDSDGAIEGHLREVGLTFHLQERVPELISANIERLLEESFKPLGISDWNSIFWVAHPGGPAILNSVEAKAGLEKARLRATRHVLSEYGNMSSACVLFILDEMRKFSAEDGRTTTGEGMDWGVLFGFGPGLTVETIVLHSVRIANGRAA
>rna-gnl|WGS:LWDX|Do020464.1_mrna
MGIGKAVPSHEFQQKSFSDYYFEITSSNHMVDLKAKFANICEKTMIEKRHFYMSNEMLRDSPSITAYSSTSLTRRQELADVGVPELGAKAARKAICDWGKQASDITHLVASTSSSGCMPGADCELARLLGLKPSTKRFMLYQTGCHGGCMALSLSKDLAENNPGARVLVVCSEVCTLSLRGPSESHIGDLVGQAILGDAAGAVVVGSSPAADEHTIFELVLTCQETIPGTEEALVSKLREEGILYSLHRDIPLHVSSSIERLVELMLKETMAPVPDLNEEVFWVVHPGGRGILDWIEGKLGLREEKLAASRSVMRQYGNTRCSSVILVMEEMRRRSEQHGLRTAGEGLDWGLLVGYGPGITVEAILLTALPDKAII
>rna-gnl|WGS:LWDX|Do024559.1_mrna
LLEEVPKLGAAAGEKAIREWGQQRSRIKHLIFCTTSGVDMLGADYQLTKLLGLCPSMMNRVRLYHQGCFAGGMVLRVARDLAENNCGARVLIVCSEITVVTFRGLFKSHHYYKTGHQCRYISTGLI
>rna-gnl|WGS:LWDX|Do003568.1_mrna
MAFIGDGASAVVVGADSVAAAGEEEAEKPLFEIVRSKQLTLPGTSDAMRGLIREMGMTVDIVREVPSLFAGNVEAALRGLLGGPGGGLVGDVVGGDWNKMFWSMHYPGGRLVLDKVEAALGLDPAKMRASRARCSPSSTRDPNASRVPSEVAMKFITETN
>rna-gnl|WGS:LWDX|Do003826.1_mrna
MGSSAPATVVSEIRRAHQRADGSAAVLGIGTATPPNCVPQDGYVDYYFRVTNSDHLTDLKAKLDRICNKSGIKQRFIHLTEEIVAANPDFTDRASPSLDAPVDITFAAVPELAESAAAKVIAEWGRPATEITHLVFSTGSAGVTPENQPHGLPHHAQPPRLRRRGQVAPARQGYRREQRGARVLVACSEVTLIAFYGPGDGCLDHILGQALFGDGDGDGAVIVPRLLGSNVERCLIDALDELGVSARWNDLFWAIHHGGRAILDRIEGVLGLDESELAASRHVLSEFGNMSSTTVIYVLDELRRRRAAKQDGGEAPEWGVMMAFRPGITIETMVLRAPAASLMEGN
>rna-gnl|WGS:LWDX|Do026613.1_mrna
MSDELLRSNPSITAYKSPSVTLRQELADEEVPSTTGAAKQASDITHLVFCASSTGCLPGADWELVQLLGLPPATKRVMLSPSKDLAENNPGARVLVVCSKVIPLSLRGPSESHVGQAIFGDAAGAVVVGSDPDPGAGERGVFELVWTSQEIVPGTRDGWCSPCTGTCRSTCPAPDVNGEVF
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University