Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Descurainia sophioides
Species name
Descurainia sophioides is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Descurainia_sophioides.HIDH.fa
Download
>Desop.0030s0180.1.v1.1
MEDSEITSEFLPFIRTYKDGRVDRLTGTDIIPASLDPTNDVVSKDVVYSPDHNLSVRIFLPNKFSTSNKKLPLLIYIHGGAWIIESPFSPIYHNYVTEVVKSANCLAVSIQYRRAPEYPVPAAYEDSWSAIQWIFSHSDGSGPEDWINKHADFEKVFIAGDSAGGNISHHMAVRAGKEKLDPRIKGIVIVHPAFWGTDPVDELDVQDKEIRSGIAELWEKVASPNSVNGTDDPLFNVNGSGSDFSGLGCEKVLVAVAGEDVFVRQGLAYAANLGKCEWKGNVEVIKEEGEGHVFHLQNPNSEKALNFLKKFVEFING
>Desop.0030s0179.1.v1.1
MLRRITCSSSIASPSLFFRFFRQFPRSYSSPTTIAVSGRNIRWLSTTTTLRCICSHSSSEIISEHPPFVRFYKDGRVERLSGTETVSASLIPQNDVVSKDVVYSSENYLSVRLFLPHKIAAGNKLPLLIYIHGGGWIIGSPFAPIYHNFLTEIVKSANCLAVSIQYRLAPENPVPAAYEDAWSAIQWIFSHSGGSGPEDWINKHADFDRVFLAGDSAGGNISHHMAVRAGKGKLEPRIKGTMIVHPAFWGKEPVDEHDVQDREIRDGVAEVWEKIASPNSVDGTDDPWFNVVGSGSDFSGLGCDKVLVVVAGKDLFVRQGLGYAEKLKKSGWKGEVEVMEEEDEDHCFHLLNPDSENTPKFMKRFVNFITG
>Desop.0030s0178.1.v1.1
MESDRTTERHLPLIRIHENGRVERLSGNDIIPASLDTQNEVVSKDDVYSPEHDLSVRLFLPHQSTHLAAGNKLPLLIYFHGGGYIVQSPFSPVYHNYLTELVKTANCLAVSVQYRLAPEHPIPAAYDDSWSAIQWIFAHSDGWINDFADFNRVFLAGDSAGANIAHHMAIRAGKEKLNPRIKGVVMVHPGFWGKDPIDEHDVQDEGIRRRIKDMWEKIISPNSVDGVNDPWFNVVGSGSDISGLGCEKVLVAVAGKDVFWRQGLAYVAKLKKSGWNGVTQVVEDEEEGHCFHLHSHNSQNASKLMNKFVEFIIKR
>Desop.0206s0560.1.v1.1
MGATTLTHMTTVNPNNTNIHGPVVDEVEGLIRVYKDGQVERSQIVPCVGPSLPLELGVACSDVNIDKLTNVWARLYVPMMTTTKSSVSNKLPLLVYFHGGGFCMGSASWSCYHEFLAKLSARSQCLVMSVNYRLAPENPLPAAYEDGVNAILWLNKARSDNLWAKLCDFGRIFLAGDSAGGNIAHHVAARLASIDDLALKIEGMILIQPFFGGEARTASERRVENNKSSVLTLAASDAWWRLALPRDANREHPYCKPVKIKSLTVMRTLVCVAEMDLLMDRNMEMCDDNVKTIKRVVYRGVGHAFQILGKSQLAHTTTLEMLCHIDAFIHHYDPFN
>Desop.0207s0399.1.v1.1
MDSEIAFDCSPMFKIYKSGRIERLMGETTVPPSSEPKNGVVSKDVVYSPDNNLSIRIYLPEKTTAAENSEKLPLLVYFHGGGFVLETAFSPTYHNFLTAAVSASDCVAVSVDYRRAPEHPIPTSYDDSWTALKWAFSHIARSGQEEWLNKHADFSKVFLAGDSAGANIVHHMAMKAAKEKLSPDLNDSGIFGIILVHPYFWSKTPIDDKEVKDVVLRMNIESFWKLASPNSKDGSDDPLINVVQSESVDLSGLGCGKVLVLVAEKDALVRQGWGYAAKLEKSGWKGELEVVESEGEDHVFHLMKPDCEKALEAMHKFARFIKGEN
>Desop.0207s0398.1.v1.1
MDSEIAADYSPMLIIYKSGRIERLMGETTVPPSTNPQSGVISKDVVYSPDDNLTVRIYIPEKAADETHTAAKLPLLVYFHGGGFIIETAFSPTYHNFLTAAVSASDCVAVSVDYRRAPEHPIPTSYDDSWTALEWVFSHVAESGSEDWLNKHADFSKVFLAGDSAGANITHHMAMKAAKEKLSPELEKSGISGFILVHPYFWSKTPVDDKETTDVAIRTRIESFWTLASPNSKDGLDDPFINVVQSELVDLSGLDCAKVLVMVAEKDKLVRQGLGYAAKLGKSRWKGKPEVMESEGEGHVFHLKEPNSDKALQLMHKFAAFLNS
>Desop.0236s0146.1.v1.1
MASFPKTSSTRRRNLSVRIYLPEKVSVTNEKLPILIYFHGGGFIIETAFSPTCHTFLTSAVAAANCLAISVDYCRAPEFPIPIPYEDSWDSLKWVFTHISGSGPENWINKHGDFGKVFLAGDSAGGNISHHLTIQAKREKLYDSLITGIILIHPYFWGKNPIDEFEIRDVIKAQKIEGSWGIASPNSKDGVDDPWINVVGSDSTDLSGLCCGRVLVMVAGDDQFVRQGWCYGEKLKKSGWEGEVEVMETKNEGHVFHLRDPNTDNARHVVKKLAEFINK
>Desop.0240s1074.1.v1.1
MATISFSHSHQSSENRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTLHPSVKAKAFDIKLSNDTSARVYIPDVAASPSVTLPLLVYFHGGGFCVGSAAWSCYHEFLTNLAVKARCVVVSVNYRLAPEHRLPAAYEDGVNVVSWLVKQQISNGGYSSWVSKCNLSNVFLAGDSAGANIAYQVAVRITASCRSVNAINLKGIILIHPFFGGESRTSSEKQQHHTKSSALTLSASDTYWRLALPRGAGRDHPWCNPLVSSVGAKLPTTMVFMAEFDILKDRNMEMCKVMRNHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFIHP
>Desop.0248s1252.1.v1.1
MESEIAMDYSPRFRIFKNGRIERLVPDIFVPPSLTPENGVVSKDAVYSPEKNLSLRIYLPQNSVHHTIEKKIPLLIYFHGGGFIMETAFSPIYHTFVTSAVSAADCMAVSVDYRRAPEHPIPVAYEDSWDAVKWIFSHMAGSGQEDWLNKHADFRKVFLAGDSAGANIAHHMAIKAGKEKVRLSGMILFHPYFMSKASVEEMEVGAKIYNEGLWRIASPSSENGVEDPWINVVGSDLSGLGCGRVLVMVAGNDVFAKGGWSYAAKLEKSGWKGKVEVMETKEEGHVFHIKNPDSDNVRRVLHNLSEFLITDETS
>Desop.0248s2043.1.v1.1
MESKKKQITLELLPWLVVHSDGTLERLAGTEVCPPGLNPETGVLSKDIIIEPKTGLSARIYRPDSIQPGQKLPIALYFHGGAFLIASASVPGYHTSVNKLVAQANIIAVSVNYRLAPEHPLPTAYEDSWTVLQTIQTINEPWINDYADFNRFFLVGDSAGANVSHHLAFQAKQSNQTLKIEGIGMIHPYFWGTKPIGLEVNDVGRKQMVDGWWEFVCPSKKGSDDPWINPFTDGSPDLEGLGCERVMITVAEKDILNERGKLYYERLVKSKWRGKVEIMETKGKDHVFHIFEPDCDEAIAMVRRLALFINQVEA
MEDSEITSEFLPFIRTYKDGRVDRLTGTDIIPASLDPTNDVVSKDVVYSPDHNLSVRIFLPNKFSTSNKKLPLLIYIHGGAWIIESPFSPIYHNYVTEVVKSANCLAVSIQYRRAPEYPVPAAYEDSWSAIQWIFSHSDGSGPEDWINKHADFEKVFIAGDSAGGNISHHMAVRAGKEKLDPRIKGIVIVHPAFWGTDPVDELDVQDKEIRSGIAELWEKVASPNSVNGTDDPLFNVNGSGSDFSGLGCEKVLVAVAGEDVFVRQGLAYAANLGKCEWKGNVEVIKEEGEGHVFHLQNPNSEKALNFLKKFVEFING
>Desop.0030s0179.1.v1.1
MLRRITCSSSIASPSLFFRFFRQFPRSYSSPTTIAVSGRNIRWLSTTTTLRCICSHSSSEIISEHPPFVRFYKDGRVERLSGTETVSASLIPQNDVVSKDVVYSSENYLSVRLFLPHKIAAGNKLPLLIYIHGGGWIIGSPFAPIYHNFLTEIVKSANCLAVSIQYRLAPENPVPAAYEDAWSAIQWIFSHSGGSGPEDWINKHADFDRVFLAGDSAGGNISHHMAVRAGKGKLEPRIKGTMIVHPAFWGKEPVDEHDVQDREIRDGVAEVWEKIASPNSVDGTDDPWFNVVGSGSDFSGLGCDKVLVVVAGKDLFVRQGLGYAEKLKKSGWKGEVEVMEEEDEDHCFHLLNPDSENTPKFMKRFVNFITG
>Desop.0030s0178.1.v1.1
MESDRTTERHLPLIRIHENGRVERLSGNDIIPASLDTQNEVVSKDDVYSPEHDLSVRLFLPHQSTHLAAGNKLPLLIYFHGGGYIVQSPFSPVYHNYLTELVKTANCLAVSVQYRLAPEHPIPAAYDDSWSAIQWIFAHSDGWINDFADFNRVFLAGDSAGANIAHHMAIRAGKEKLNPRIKGVVMVHPGFWGKDPIDEHDVQDEGIRRRIKDMWEKIISPNSVDGVNDPWFNVVGSGSDISGLGCEKVLVAVAGKDVFWRQGLAYVAKLKKSGWNGVTQVVEDEEEGHCFHLHSHNSQNASKLMNKFVEFIIKR
>Desop.0206s0560.1.v1.1
MGATTLTHMTTVNPNNTNIHGPVVDEVEGLIRVYKDGQVERSQIVPCVGPSLPLELGVACSDVNIDKLTNVWARLYVPMMTTTKSSVSNKLPLLVYFHGGGFCMGSASWSCYHEFLAKLSARSQCLVMSVNYRLAPENPLPAAYEDGVNAILWLNKARSDNLWAKLCDFGRIFLAGDSAGGNIAHHVAARLASIDDLALKIEGMILIQPFFGGEARTASERRVENNKSSVLTLAASDAWWRLALPRDANREHPYCKPVKIKSLTVMRTLVCVAEMDLLMDRNMEMCDDNVKTIKRVVYRGVGHAFQILGKSQLAHTTTLEMLCHIDAFIHHYDPFN
>Desop.0207s0399.1.v1.1
MDSEIAFDCSPMFKIYKSGRIERLMGETTVPPSSEPKNGVVSKDVVYSPDNNLSIRIYLPEKTTAAENSEKLPLLVYFHGGGFVLETAFSPTYHNFLTAAVSASDCVAVSVDYRRAPEHPIPTSYDDSWTALKWAFSHIARSGQEEWLNKHADFSKVFLAGDSAGANIVHHMAMKAAKEKLSPDLNDSGIFGIILVHPYFWSKTPIDDKEVKDVVLRMNIESFWKLASPNSKDGSDDPLINVVQSESVDLSGLGCGKVLVLVAEKDALVRQGWGYAAKLEKSGWKGELEVVESEGEDHVFHLMKPDCEKALEAMHKFARFIKGEN
>Desop.0207s0398.1.v1.1
MDSEIAADYSPMLIIYKSGRIERLMGETTVPPSTNPQSGVISKDVVYSPDDNLTVRIYIPEKAADETHTAAKLPLLVYFHGGGFIIETAFSPTYHNFLTAAVSASDCVAVSVDYRRAPEHPIPTSYDDSWTALEWVFSHVAESGSEDWLNKHADFSKVFLAGDSAGANITHHMAMKAAKEKLSPELEKSGISGFILVHPYFWSKTPVDDKETTDVAIRTRIESFWTLASPNSKDGLDDPFINVVQSELVDLSGLDCAKVLVMVAEKDKLVRQGLGYAAKLGKSRWKGKPEVMESEGEGHVFHLKEPNSDKALQLMHKFAAFLNS
>Desop.0236s0146.1.v1.1
MASFPKTSSTRRRNLSVRIYLPEKVSVTNEKLPILIYFHGGGFIIETAFSPTCHTFLTSAVAAANCLAISVDYCRAPEFPIPIPYEDSWDSLKWVFTHISGSGPENWINKHGDFGKVFLAGDSAGGNISHHLTIQAKREKLYDSLITGIILIHPYFWGKNPIDEFEIRDVIKAQKIEGSWGIASPNSKDGVDDPWINVVGSDSTDLSGLCCGRVLVMVAGDDQFVRQGWCYGEKLKKSGWEGEVEVMETKNEGHVFHLRDPNTDNARHVVKKLAEFINK
>Desop.0240s1074.1.v1.1
MATISFSHSHQSSENRRGGSHHHRHGPVVEEIEGLIKVFNDGCVERPPIVPTVSPTLHPSVKAKAFDIKLSNDTSARVYIPDVAASPSVTLPLLVYFHGGGFCVGSAAWSCYHEFLTNLAVKARCVVVSVNYRLAPEHRLPAAYEDGVNVVSWLVKQQISNGGYSSWVSKCNLSNVFLAGDSAGANIAYQVAVRITASCRSVNAINLKGIILIHPFFGGESRTSSEKQQHHTKSSALTLSASDTYWRLALPRGAGRDHPWCNPLVSSVGAKLPTTMVFMAEFDILKDRNMEMCKVMRNHGKRVEGIVHGGVGHAFHILDNSSVSRDRIHDMMCRLHNFIHP
>Desop.0248s1252.1.v1.1
MESEIAMDYSPRFRIFKNGRIERLVPDIFVPPSLTPENGVVSKDAVYSPEKNLSLRIYLPQNSVHHTIEKKIPLLIYFHGGGFIMETAFSPIYHTFVTSAVSAADCMAVSVDYRRAPEHPIPVAYEDSWDAVKWIFSHMAGSGQEDWLNKHADFRKVFLAGDSAGANIAHHMAIKAGKEKVRLSGMILFHPYFMSKASVEEMEVGAKIYNEGLWRIASPSSENGVEDPWINVVGSDLSGLGCGRVLVMVAGNDVFAKGGWSYAAKLEKSGWKGKVEVMETKEEGHVFHIKNPDSDNVRRVLHNLSEFLITDETS
>Desop.0248s2043.1.v1.1
MESKKKQITLELLPWLVVHSDGTLERLAGTEVCPPGLNPETGVLSKDIIIEPKTGLSARIYRPDSIQPGQKLPIALYFHGGAFLIASASVPGYHTSVNKLVAQANIIAVSVNYRLAPEHPLPTAYEDSWTVLQTIQTINEPWINDYADFNRFFLVGDSAGANVSHHLAFQAKQSNQTLKIEGIGMIHPYFWGTKPIGLEVNDVGRKQMVDGWWEFVCPSKKGSDDPWINPFTDGSPDLEGLGCERVMITVAEKDILNERGKLYYERLVKSKWRGKVEIMETKGKDHVFHIFEPDCDEAIAMVRRLALFINQVEA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University