Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Descurainia sophioides
Species name
Descurainia sophioides is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Descurainia_sophioides.CHS.fa
Download
>Desop.0033s0240.1.v1.1
MSNSGMNGVEKLSSISARRVANPGKATVLSLGKAFPSQVVPQENLVEGFLRDTKCDDAFIKEKLEHLCKTTTVKTRYTVLSREILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGADPRECEAPFMELHYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEENIEEFCKKLMGKAGDESMEFNDMFWAVHPGGPAILNRLETKLKLEREKLESSRRALVDYGNVSSNTILYVMEYMRDELKKKGNAAEEWGLGLAFGPGITFEGLLIRSLTSPA
>Desop.0041s0003.1.v1.1
MAPSLEEIRKAQRADGPAAIMAIGTANPPNQVLQADYPDYYFRITNSDYMTDLKEKFKRICAKTMIRRRHMYLTEEILKENPNMCAFMAPSLDARQDMVVVEVPRLGKEAAMRAIEEWGQPKSKITHVVFCTTSGVDMPGADYRLTKLLGLCPSVKRVMMYNQGCYAGGTVLRLAKDLAENNRGARVLVVCSECIGMFFRGPSSNHIDSLVGQALFGDGAAALIVGSDPDTSIGEKPIFEMVYAAQTIVPDSEGAVDLKLREAGLTFHLRKDVPALIAKNIGKSLEDAFKPLGVSDWNSLFWVAHPGGPAILDQIEIKLGLNKEKMRATRHVLSEYGNMASVCVLFILDEIRKKSAEDGSSTSGEGLEWGVLLGIGPGLTVETVVLRSVPVDSSPL
>Desop.0222s0481.1.v1.1
MLGSRSVEKQKERRVANQGKATVLALGKAFPSNVVSQENLVEEYLREIKCDDLSIKDKLQHLCKTTTVKTRYMVMSRETLHKYPELATEGSPTIKQRLGIANEAVVQMAYEASLACIKEWGRVVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGLSGLRLAKDIAENNPGSRVLLTTSETTVLGFRPPNKARPYDLVGAALFGDGAAALIIGADPTESESPFMELHCALQQFLPGTQGVINGRLSEEGISFKLGRDLPQKIEDNVEEFCKKLMAKVSSGSGSLELNDLFWAVHPGGPAILNGLETKLKLKPEKLTCSRKALMDYGNVSSNTIFYIIDKVRDELEEKGRGGEEWGLGLAFGPGITFEGFLMRSL
>Desop.0230s0197.1.v1.1
MGSIDATELGSEKKPNLGKATILAIGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILRKYPELAIEGGSTVTQRLDICNDAVTEMAVEASRACIKTWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPICEKPLFELHTAIQNFLPDTEKTIDGRLTEQGINFKLARELPQIIEDNVENFCKKLIGKAGLAHKDYNQMFWAVHPGGPAILNRMEKRLNLSPDKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKARNMNEGENEWGLILAFGPGVTFEGIVARNLDV
>Desop.0240s1289.1.v1.1
MVMAGASSLDEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPHMCAYMAPSLDTRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSAKDGVATTGEGLEWGVLFGFGPGLSVETVVLHSVPL
>Desop.0241s0009.1.v1.1
MAIGMANSPNQELQAEYPDYYFRITNSDHMTDLKEKFKRICAKTMVRRRHMYLTEEILKENPNMCAFMAPSLDARQDMVVVEVPRLGKEAAMRAIEEWGQPNSKITHVVFCTTSGVDMPGADYRLT
MSNSGMNGVEKLSSISARRVANPGKATVLSLGKAFPSQVVPQENLVEGFLRDTKCDDAFIKEKLEHLCKTTTVKTRYTVLSREILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLGCIKEWGRPVEDITHIVYVSSSEIRLPGGDLYLSAKLGLRNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGADPRECEAPFMELHYAVQQFLPGTQNVIDGRLSEEGINFKLGRDLPQKIEENIEEFCKKLMGKAGDESMEFNDMFWAVHPGGPAILNRLETKLKLEREKLESSRRALVDYGNVSSNTILYVMEYMRDELKKKGNAAEEWGLGLAFGPGITFEGLLIRSLTSPA
>Desop.0041s0003.1.v1.1
MAPSLEEIRKAQRADGPAAIMAIGTANPPNQVLQADYPDYYFRITNSDYMTDLKEKFKRICAKTMIRRRHMYLTEEILKENPNMCAFMAPSLDARQDMVVVEVPRLGKEAAMRAIEEWGQPKSKITHVVFCTTSGVDMPGADYRLTKLLGLCPSVKRVMMYNQGCYAGGTVLRLAKDLAENNRGARVLVVCSECIGMFFRGPSSNHIDSLVGQALFGDGAAALIVGSDPDTSIGEKPIFEMVYAAQTIVPDSEGAVDLKLREAGLTFHLRKDVPALIAKNIGKSLEDAFKPLGVSDWNSLFWVAHPGGPAILDQIEIKLGLNKEKMRATRHVLSEYGNMASVCVLFILDEIRKKSAEDGSSTSGEGLEWGVLLGIGPGLTVETVVLRSVPVDSSPL
>Desop.0222s0481.1.v1.1
MLGSRSVEKQKERRVANQGKATVLALGKAFPSNVVSQENLVEEYLREIKCDDLSIKDKLQHLCKTTTVKTRYMVMSRETLHKYPELATEGSPTIKQRLGIANEAVVQMAYEASLACIKEWGRVVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGLSGLRLAKDIAENNPGSRVLLTTSETTVLGFRPPNKARPYDLVGAALFGDGAAALIIGADPTESESPFMELHCALQQFLPGTQGVINGRLSEEGISFKLGRDLPQKIEDNVEEFCKKLMAKVSSGSGSLELNDLFWAVHPGGPAILNGLETKLKLKPEKLTCSRKALMDYGNVSSNTIFYIIDKVRDELEEKGRGGEEWGLGLAFGPGITFEGFLMRSL
>Desop.0230s0197.1.v1.1
MGSIDATELGSEKKPNLGKATILAIGKAFPHQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILRKYPELAIEGGSTVTQRLDICNDAVTEMAVEASRACIKTWGRSISDITHLVYVSSSEARLPGGDLYLAKGLGLSPETHRVLLYFVGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPICEKPLFELHTAIQNFLPDTEKTIDGRLTEQGINFKLARELPQIIEDNVENFCKKLIGKAGLAHKDYNQMFWAVHPGGPAILNRMEKRLNLSPDKLSPSRRALMDYGNASSNSIVYVLEYMLEESRKARNMNEGENEWGLILAFGPGVTFEGIVARNLDV
>Desop.0240s1289.1.v1.1
MVMAGASSLDEIRKAQRADGPAGILAIGTANPANHVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPHMCAYMAPSLDTRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGISDWNSLFWIAHPGGPAILDQVEIKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSAKDGVATTGEGLEWGVLFGFGPGLSVETVVLHSVPL
>Desop.0241s0009.1.v1.1
MAIGMANSPNQELQAEYPDYYFRITNSDHMTDLKEKFKRICAKTMVRRRHMYLTEEILKENPNMCAFMAPSLDARQDMVVVEVPRLGKEAAMRAIEEWGQPNSKITHVVFCTTSGVDMPGADYRLT
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University