Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Descurainia sophioides
Species name
Descurainia sophioides is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Descurainia_sophioides.4CL.fa
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>Desop.0039s0033.1.v1.1
MEKSGYGRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYPSKPAIIDSDSGDSLSFSDLKSAVARLAHGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVNEVSKQIKDSNPKIIISVNQLFDKVKGFNLPIVLLGSGDSVKIPESNTKILSFNDVMELSEPVSEIPFVEIKQSDTATLLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLTVITYAQLQRGNALVSMAKFDLETVLMNIEKYRVTQLWVVPPVFLALAKQSIVKKYDLSSLKYIGSGAAPLGKDLMDECGRNIPNVLLMQGYGMTETCGIVSVEDPRLGKRNTGSAGMLAPGVEAQIVSIETGKSQPPTQLGEIWVRGRNMMKGYLNNPQATKETIDKKGWVHTGDLGYFDEDGNLYVVDRIKELIKYRGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIGFVVRSPNSSITEEDIKQFIAKQVAPFKKLRRVSFINVVPKSAAGKILRRELVQQVRSKM
>Desop.0097s0091.1.v1.1
MVLQQQTHFLTKETDQEEPSHDFIFRSKLPDIFIPNHLPLTDYVFHKFSGDGDGDSTTTCLIDGATGRIFTYADVKINSRRIAAGIHRLGIRHRDVVMLLLPNSPEFALSFLAVAYLGAISTTANPYYTQPEITKQAKASATKMIITKRCYVDKLTNLKNDGILIVCVDDEDDVVTSTDGSVSFTELTQADETELPKPEISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLNFTSDDVICCFLPMFHIYALDALMLSAMRTGAALLIVPRFEMNLVMELIQRYKVTVVPVAPPVVLAFVKSPETERYDLSSVRMMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPSKTKSGACGTVIRNAEMKVVDTITGISLPRNKSGEICVRGQQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPFIDDAAVVAMKDEVADEVPVAFVVRSEESQLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKELRAKLETEYSSN
>Desop.0097s0092.1.v1.1
MLAQEAMINDQKQSSSSDVIFRSKLPDIYIANHLPLHDYIFENISEHSDKPCLINGPTGQVYSYADVHATSRKIAAGLQKLGVKQHDVVMLLLPNSPEVVLTFLAASFNGAIITSANPFFTPAEISKQAKASAAKLIVTQSQYTGKIKNLQNDGVLIVCTDSDDIPESCLRFSELTQSGEEEQEPRVNSEISPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFHREDVILCVLPMFHIYAINSIMLCSLRVGATILIMPKFEITLLLEQIQRCKVTVAMVVPPIVLAMTKSPETEKYDLSSVRIIKSGAAPLGKELEDAISAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLPRNKSGEICIRGHQIMKGYLNDPAATASTIDKDGWLHTGDVGFIDEDDELFIVDRLKELIKYKGFQVAPAELESLLITHQDINDVAVVAMKEEDAGEVPVAFVVRSKDSNISEDEIKQFVSKQVVFYKRINKVFFTDSIPKAPSGKILRKDLRARLANGLMN
>Desop.0196s0118.1.v1.1
MAPPQEVMEKQNNNNSDVIFRSKLPDIYIPNHLSLHDYIFQNISEFASKPCLINGPTGHVYTYSDVHDISRRVAASFHKLGVNQDDVVMILLPNSPEFVLSFLAASFRGATATAANPFFTPAEIAKQAKASNSKLIVTESRYVDKIKSLQTEDGVIIVCTDDNESVPIPEGCLRFSELTQSNETDVISSVEISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEIHLLLELIQRCKVTVAPMVPPIVLAIAKSAETEKYDLSSIRVVKSGAAPLGKELEDAVSAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSKNKPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLISHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELTEDEVKQFVSKQVVFYKRINKVFFSESIPKAPSGKILRKDLRAKLANGL
>Desop.0206s0281.1.v1.1
MEGQKLDNEYIFRSLYPSVPIPDKLTLPEFVLQGVEEFTEKVAFVEAVTGKAVTYGDVVRDTKRLAKALTSLGLRKGQVMVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGIITDATNYEKVKTLGLPVIVLGEDKIEGAVNWKDLLEAGDKSGDNDKEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSTLFSVRSEMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRIFLNALIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLNAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGKSLPKNTSGELCVRSQCVMQGYFMNKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVINPKATEKEEDILNFVAANVTHYKKVRAVHFVDSIPKSLSGKIMRRLLRDKILSINKK
>Desop.0243s0597.1.v1.1
MAATPLHISPNPKTPTSHQNPPFWFSPETGIYTSKFPSINFPVDPILDAVSALFSHTHHGDVALVDSSTGFSISHVELQIMVKSMAARIYHDLGVQQGDVVSLVLPNSVYFPLIFLSLISLGAIVTTMNPSSSLGEIKKQVSECNVGLAFTSSENVEKLSSLGVMVIRVPESYDFDSIRIENPKFYSIIKGDFGFVPKPLIKQDDVAAIMYSSGTTGASKGVLLTHRNLIASMELFVRFEASQYEYPGSSNVYLAVLPLCHIYGLSLFVLGLLSLGSTIVVMRRFDASDVINVIERFNITHFPVVPPMLMALTKKAKEVCGEVFKSLKQVSSGAAPLSRKFIEDFLQTLPHVDLIQGYGMTESTAVGTRGFNSEKLNRYSSVGQLAPNMQAKVVDWSSGSFLPPGNRGELWIQGPGVMKGYLQNPEATQLTIVDDSWLRTGDIAYFDEDGYLFIVDRMKEIIKYKGFQIAPADLEAVLVSHPLIIDAAVTAAPDDECGEIPVAFVVRRQETTLSEQDVISYVASQVAPYRKVRKVVMVSSIPKSPTGKILRKELKRILKNSVSSRL
>Desop.0248s2165.1.v1.1
MITATLHEPQIHQPTDTSVPLPPPTVISGDTPPPTPRIFRSKLPDINIPNHLPLHTYCFEKLSSVSEKPCLIVGSTGKSYTYGETHLICRKVAAGFYKLGIRKGDVIMILLQNSAEFVFSFMGASMIGAISTTANPFYTSQEIYKQLQSSKAKLIITHSQYVEKLKDLKEDLTVITTEDPTPEKCLSFSTLITTDETYPLDSMDVSGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLKPNDVVLCVLPLFHIYSLNSVLLNSIRSGATVLLMHKFEIGALLDLIQRHRVTITALVPPLVIALAKNSAVNSYDLSSVRLVLSGAAPLGKDLQDSLRRRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPMPTKSGSCGTVVRNAELKVVHLETNISLGYNQPGEICIRGQQIMKEYLNDPEATAATIDEEGWLHTGDIGYVDDDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHNLIADAAVVPQNDEVAGEVPVAFVVRSNGNDITEEEIKEYISKQVVFYKRLHRVFFVASIPKSPSGKILRKDLKAKLC
MEKSGYGRDGIYRSLRPTLVLPKDPNTSLVSFLFRNSSSYPSKPAIIDSDSGDSLSFSDLKSAVARLAHGFLRLGIRKNDVVLIFAPNSYQFPLCFLAVTAIGGVFTTANPLYTVNEVSKQIKDSNPKIIISVNQLFDKVKGFNLPIVLLGSGDSVKIPESNTKILSFNDVMELSEPVSEIPFVEIKQSDTATLLYSSGTTGTSKGVELTHGNFIAASLMVTMDQDLMGEYHGVFLCFLPMFHVFGLTVITYAQLQRGNALVSMAKFDLETVLMNIEKYRVTQLWVVPPVFLALAKQSIVKKYDLSSLKYIGSGAAPLGKDLMDECGRNIPNVLLMQGYGMTETCGIVSVEDPRLGKRNTGSAGMLAPGVEAQIVSIETGKSQPPTQLGEIWVRGRNMMKGYLNNPQATKETIDKKGWVHTGDLGYFDEDGNLYVVDRIKELIKYRGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIGFVVRSPNSSITEEDIKQFIAKQVAPFKKLRRVSFINVVPKSAAGKILRRELVQQVRSKM
>Desop.0097s0091.1.v1.1
MVLQQQTHFLTKETDQEEPSHDFIFRSKLPDIFIPNHLPLTDYVFHKFSGDGDGDSTTTCLIDGATGRIFTYADVKINSRRIAAGIHRLGIRHRDVVMLLLPNSPEFALSFLAVAYLGAISTTANPYYTQPEITKQAKASATKMIITKRCYVDKLTNLKNDGILIVCVDDEDDVVTSTDGSVSFTELTQADETELPKPEISPEDTVAMPYSSGTTGLPKGVMITHKGLVTSIAQKVDGENPNLNFTSDDVICCFLPMFHIYALDALMLSAMRTGAALLIVPRFEMNLVMELIQRYKVTVVPVAPPVVLAFVKSPETERYDLSSVRMMLSGAATLKKELEDAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKNPSKTKSGACGTVIRNAEMKVVDTITGISLPRNKSGEICVRGQQLMKGYLNDPEATARTIDKDGWLHTGDIGFVDDDDEIFIVDRLKELIKFKGYQVAPAELEALLISHPFIDDAAVVAMKDEVADEVPVAFVVRSEESQLTEDDVKSYVNKQVVHYKRIKMVFFIEAIPKAVSGKILRKELRAKLETEYSSN
>Desop.0097s0092.1.v1.1
MLAQEAMINDQKQSSSSDVIFRSKLPDIYIANHLPLHDYIFENISEHSDKPCLINGPTGQVYSYADVHATSRKIAAGLQKLGVKQHDVVMLLLPNSPEVVLTFLAASFNGAIITSANPFFTPAEISKQAKASAAKLIVTQSQYTGKIKNLQNDGVLIVCTDSDDIPESCLRFSELTQSGEEEQEPRVNSEISPDDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFHREDVILCVLPMFHIYAINSIMLCSLRVGATILIMPKFEITLLLEQIQRCKVTVAMVVPPIVLAMTKSPETEKYDLSSVRIIKSGAAPLGKELEDAISAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLPRNKSGEICIRGHQIMKGYLNDPAATASTIDKDGWLHTGDVGFIDEDDELFIVDRLKELIKYKGFQVAPAELESLLITHQDINDVAVVAMKEEDAGEVPVAFVVRSKDSNISEDEIKQFVSKQVVFYKRINKVFFTDSIPKAPSGKILRKDLRARLANGLMN
>Desop.0196s0118.1.v1.1
MAPPQEVMEKQNNNNSDVIFRSKLPDIYIPNHLSLHDYIFQNISEFASKPCLINGPTGHVYTYSDVHDISRRVAASFHKLGVNQDDVVMILLPNSPEFVLSFLAASFRGATATAANPFFTPAEIAKQAKASNSKLIVTESRYVDKIKSLQTEDGVIIVCTDDNESVPIPEGCLRFSELTQSNETDVISSVEISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEIHLLLELIQRCKVTVAPMVPPIVLAIAKSAETEKYDLSSIRVVKSGAAPLGKELEDAVSAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKIVDPDTGDSLSKNKPGEICIRGHQIMKGYLNNPAATAETIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGFQVAPAELEALLISHPDITDVAVVAMKEEAAGEVPVAFVVKSKDSELTEDEVKQFVSKQVVFYKRINKVFFSESIPKAPSGKILRKDLRAKLANGL
>Desop.0206s0281.1.v1.1
MEGQKLDNEYIFRSLYPSVPIPDKLTLPEFVLQGVEEFTEKVAFVEAVTGKAVTYGDVVRDTKRLAKALTSLGLRKGQVMVVVLPNVAEYGIIALGIMSAGGVFSGANPTALVSEIKKQVEASGARGIITDATNYEKVKTLGLPVIVLGEDKIEGAVNWKDLLEAGDKSGDNDKEEILQTDLCALPFSSGTTGLQKGVMLTHRNLIANLCSTLFSVRSEMIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRYDLRIFLNALIAHEVSFAPIVPPIILNLVKNPIVDEFDLSKLKLRSVMTAAAPLAPELLNAFEAKFPNVQVQEAYGLTEHSCITLTHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGKSLPKNTSGELCVRSQCVMQGYFMNKEETEKTIDEEGWLHTGDIGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAACVVINPKATEKEEDILNFVAANVTHYKKVRAVHFVDSIPKSLSGKIMRRLLRDKILSINKK
>Desop.0243s0597.1.v1.1
MAATPLHISPNPKTPTSHQNPPFWFSPETGIYTSKFPSINFPVDPILDAVSALFSHTHHGDVALVDSSTGFSISHVELQIMVKSMAARIYHDLGVQQGDVVSLVLPNSVYFPLIFLSLISLGAIVTTMNPSSSLGEIKKQVSECNVGLAFTSSENVEKLSSLGVMVIRVPESYDFDSIRIENPKFYSIIKGDFGFVPKPLIKQDDVAAIMYSSGTTGASKGVLLTHRNLIASMELFVRFEASQYEYPGSSNVYLAVLPLCHIYGLSLFVLGLLSLGSTIVVMRRFDASDVINVIERFNITHFPVVPPMLMALTKKAKEVCGEVFKSLKQVSSGAAPLSRKFIEDFLQTLPHVDLIQGYGMTESTAVGTRGFNSEKLNRYSSVGQLAPNMQAKVVDWSSGSFLPPGNRGELWIQGPGVMKGYLQNPEATQLTIVDDSWLRTGDIAYFDEDGYLFIVDRMKEIIKYKGFQIAPADLEAVLVSHPLIIDAAVTAAPDDECGEIPVAFVVRRQETTLSEQDVISYVASQVAPYRKVRKVVMVSSIPKSPTGKILRKELKRILKNSVSSRL
>Desop.0248s2165.1.v1.1
MITATLHEPQIHQPTDTSVPLPPPTVISGDTPPPTPRIFRSKLPDINIPNHLPLHTYCFEKLSSVSEKPCLIVGSTGKSYTYGETHLICRKVAAGFYKLGIRKGDVIMILLQNSAEFVFSFMGASMIGAISTTANPFYTSQEIYKQLQSSKAKLIITHSQYVEKLKDLKEDLTVITTEDPTPEKCLSFSTLITTDETYPLDSMDVSGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGDNPNLYLKPNDVVLCVLPLFHIYSLNSVLLNSIRSGATVLLMHKFEIGALLDLIQRHRVTITALVPPLVIALAKNSAVNSYDLSSVRLVLSGAAPLGKDLQDSLRRRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPMPTKSGSCGTVVRNAELKVVHLETNISLGYNQPGEICIRGQQIMKEYLNDPEATAATIDEEGWLHTGDIGYVDDDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHNLIADAAVVPQNDEVAGEVPVAFVVRSNGNDITEEEIKEYISKQVVFYKRLHRVFFVASIPKSPSGKILRKDLKAKLC
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University