Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Allium cepa
Species name
Onion (Allium cepa) is a species of monocot in the family Amaryllidaceae (amaryllis family).
Species info
Gene sequence info
Allium_cepa.HIDH.fa
Download
>g495489.t1
MACSDEIKFDSPYIRVYNNGQVQRLFPSDYISPSFDHPNTNVSSKDASINPETNLSVRIYLPKKSFENGPKKLPVVVYYHGGSFCIGSAFDSFLHNYLNVLVYKFNCILVSVEYRLAPEYPIPIAYNDSWEALKWVLSHKATQISDDNWLSTFGDFTRVFLMGDSAGANIVHHMSMKAGKKKPEEQKAEEVNKECVQETQVAQNPK
>g338643.t1
MASTTSDPTNEILLDYKSIFHVYKDGSIVRFAGTEFAPPGTDPATNVTTADVTIDPVKNITARLHVPNVVTDSSSGEIKRLPVLVYFHGGAFCYASAFLPQFQPYLNTVASRAQVLIVSVNYRLATEHLLPAAYEDSMDAIKWVRSSGSDELLVKYGDVDRLFLGGESAGANIVHHMALQAAENNLKIQGAIIIHPFFLGKHAYRFRNNRHQNAWIHRTVMESDKQAWCGHRPPLG
>g113288.t1
MIHYRGGGFVVGSAAMSQLHNYLNALVGSWLALGWVPSHATYDTDNNCRDSWLIDHADFTRVYLSRESSGANIAHNLAMLAVLNWLKPSEYDFDMRDRRKQDAEQYIGDLEAYESAGECSERRGEDELWRGATELKRLRLSTEAASGDLGLVGDGACFYLVFFFKFGIMENNDPLGYAFGM
>g518315.t1
MVHYHGGGFVVGSAAMSPLHNYLNALVGKANVILVSVNYRLATEHMVPVAYEDSWLALRWVASHAASDANNYCRDSWLIDHADFTRVYLSGESSGANIAHNLAMLAGTKQLVHDVRIRGIILIHPYFLGPEVTKSESFNPKMSSGLRRLWTIVCPSSTGVDDYRINPMADNAPSLKNIGCDNVLVCVGGKDPLKDKGIAYYHRLKEDLFEGRLELFEAQGEEHVFHVYKPASMQAQAQDKRICDFINH
>g46223.t1
MEKLWKSIAPPEMQSLDHPMLNPMAEDAPSLKGLGCKRIIICVAEKDPLMERGKAYYEAVKKSGWEGDIELIQSDGEEHVFHLKNPEGENALQLVNKIVAFVRKND
>g46242.t1
MSSANHSNQQNEPEEAVLVDCAPLFRLYTSGHVQRLLGSATAPPSANSKDVTITSNPHKISARLFLPSRLNPANSSKLPILIYYHGGAFCIESAFSPTYHNFLTKMAEEAGMVVVSVDYRLAPENLLPAAYEDAWVGLEWVFGVGVDEWVRDWGDLERVWVAGDSAGANIAHHMALRAGCTNGAIKLEGMILVHSYFWGSEKMESETCEAGIRAFMEKLWKSLTPPEMQSLDHPTLNPTAEDAPSLKGLGCKRIIICVAEKDILVERGKAYYEAVKKSGWEGDIELVQSNGEEHVFYLTNPEGDNALQLVSKIAAFVRKND
>g52116.t1
MESTTSNPTNEILLDYKSIFNVYKDDSIVRFAGTEFAPPGTDLTTNVTTADITIDPVKNITARVHVPNVVTDASSGESKMLHVLVCDCIDYRLATEHLLPGAYEDSVDAIKWVHSSGSNELLVKYGDVDRLFLGGESAG
>g64147.t1
MAEEAGMVVVSVDYRLAPENLLPAAYEDAWVGMEWVFSVGVDEWVRDWGDLGRVWVAGDSAGANIAHHMALRAGSTNGAIKLEGMILVHSYFWGSEKMESETCKAGIRAFLEKLWKSVTPPEMQSLDHPTLNPMAKDAPSLKGLGCKRIIICVAEKELLVERGKSYYEAVKKSGWEGDIELVQSDGEEHVFHLTNPEGENALQLVSKIVAFVRKND
>g89807.t1
MVSVRGRIAPLQAVHRNPKKSLSNYCQILYSYYSVTSQCTTKSSENKMDSTKEIEHNFPPFFCLYKNGDVHRFMGTSIVPPYTDPASNVLSKDVTINSETGLAARLYIPKPDDAASSKFPVLVYYHGGAFCIESAFSPTYHTFLTHLVEKAPVVVVSVNYRLAPEHKLPIAYDDSWEALQWVMSKGDAWIEKYGDFEKVFLAGDSAGANIAHQMAMRGVGMNIDGLMMIHPYFGKETADPEEKAKRSIFWKIISSTEMDDPAHNPMINGGKGTMEVACRRVIVCVAEKDFLAERGVEYHEKLKGSEWKGEVTFVSTEDEGHVFHLQNPGCDKGLELTDKLIAFIHNQ
>g177150.t1
MDPDTEIKFEYPNSFIVYKSGRIKRFPATTEVVPPSLDQTTGVLSKDVTIDARNNISARLYVRNIRKNNSKKKIPILIYIHGGAFCLYSSATPAYHTFVNSLVSKTDVIVVSVNYRLATENLLPIAYEDAWVAIMWVFGFKPDIWLSKYGDFGQVSIAGDSAGGNIVHQMVLRAEQIKIKFEGMILIDPYFWGEEPIESESTDVIDREFMRELWEVVNIPGVGNDDERINPVAKNAPSLRHVACKRALICIASEDLLVERGRLYFNTLRECGWEGDVDLFESEGEGHDFHLDKPNSEHALELMDRLVSFLDYGRKGEGMNFVYDCWVGIFHVWNRQILPFLSWRSFMLYHTKRWLALEIVYLPGRTYFRVSNIVWRFLFFIVEQQTRS
>g323196.t1
MAGSMRPLDNRSRYPSTKKKRKKILMASNNREVIDEVSNWLRIYSDGTVDRTWTGPPEPLFLLEPVPPHGTPINNVTVHDIPSNNPSFRVYFPETKPEPKTRLPILIHFHGGGFCISHATWYMYHQFYSRLASSIPAMILSPFLPLAPENRLPAAIDVCHDFLMRILSTDGFEDPFMERLKNTADMDRVFLIGDSSGGNLVHQVAAKAGPDLAGAIMLHPGFVRARRSGSEMDRSRESAMLSLEMLDKFLGYALPVGATKDHPITCPMDTELEAVRLPPLLVAVAGRDLIQDTNLEYCEAVRKAGKKVEVVVSEGVGHSFYLNKLEVDMDPVAGRRAQELLLTIKDFVNRH
>g414218.t1
MHTYKGENYKRACILSRSSPISKPTMTTTDSLTEFEECRGVLRVYSDGSIVRSPNPSFPVPIHDDGTVDWKDVQFDPTHNLFLRLYKPRSHSSKLPILFYFHGGGFCIGSRTWPNCQNYCLRLSADLNAVIISPDYRLAPEHRLPAALHDSVTSLQWLRAQATAEEPDPWLADVADFDRVFISGDSAGGTIAHHLAVRYSKADLGPIRVRGYVLLGPFFAGKERTISEAECPTDAFLNLELNDRFWRLSIPEGADLDHPIVNPFGPESVDLKKVEFERMLVVVGQCDLLRDRGVEYGEKLKGWGKPVEVVEFEGQQHGFFTIRPWSEPANELMMVFKKFIDHRRPLQRRNMTLPVCQLQ
>g477567.t1
MNQTTTRSNWSCTYKVRNIILIFPVVELAELERRQRDFYTTRNSKYRAVTFLFIIKNQTYPCSTRAKMSSASHTDQQHESEEAVLVECAPLFRLYTSGRVQRLLGTATAPPPVNSKDVTITSNPHKISARLFLPSRLNPTNSSKLPILIYYHGGAFCIESAFSPTYHNFLTKMVEEAGMVVVSVDYRLAPENLLPAAYEDAWVGLEWVFGVGVDEWVRDWGDLGRVWVAGDSAGANIAHHMALRAGSTDGVVKLEGMILVHSCLWGSKKLESETCEAEVRAWMEKLWKSIAPPEMQSLDHRMLNPMAEDAPSLKGLGCKRIIICVAEKDPLMERGKAYYEAVKKSGWEGDIELVQSDGEGHVFHLTNPEGENALQLVSKIVAFVRKND
MACSDEIKFDSPYIRVYNNGQVQRLFPSDYISPSFDHPNTNVSSKDASINPETNLSVRIYLPKKSFENGPKKLPVVVYYHGGSFCIGSAFDSFLHNYLNVLVYKFNCILVSVEYRLAPEYPIPIAYNDSWEALKWVLSHKATQISDDNWLSTFGDFTRVFLMGDSAGANIVHHMSMKAGKKKPEEQKAEEVNKECVQETQVAQNPK
>g338643.t1
MASTTSDPTNEILLDYKSIFHVYKDGSIVRFAGTEFAPPGTDPATNVTTADVTIDPVKNITARLHVPNVVTDSSSGEIKRLPVLVYFHGGAFCYASAFLPQFQPYLNTVASRAQVLIVSVNYRLATEHLLPAAYEDSMDAIKWVRSSGSDELLVKYGDVDRLFLGGESAGANIVHHMALQAAENNLKIQGAIIIHPFFLGKHAYRFRNNRHQNAWIHRTVMESDKQAWCGHRPPLG
>g113288.t1
MIHYRGGGFVVGSAAMSQLHNYLNALVGSWLALGWVPSHATYDTDNNCRDSWLIDHADFTRVYLSRESSGANIAHNLAMLAVLNWLKPSEYDFDMRDRRKQDAEQYIGDLEAYESAGECSERRGEDELWRGATELKRLRLSTEAASGDLGLVGDGACFYLVFFFKFGIMENNDPLGYAFGM
>g518315.t1
MVHYHGGGFVVGSAAMSPLHNYLNALVGKANVILVSVNYRLATEHMVPVAYEDSWLALRWVASHAASDANNYCRDSWLIDHADFTRVYLSGESSGANIAHNLAMLAGTKQLVHDVRIRGIILIHPYFLGPEVTKSESFNPKMSSGLRRLWTIVCPSSTGVDDYRINPMADNAPSLKNIGCDNVLVCVGGKDPLKDKGIAYYHRLKEDLFEGRLELFEAQGEEHVFHVYKPASMQAQAQDKRICDFINH
>g46223.t1
MEKLWKSIAPPEMQSLDHPMLNPMAEDAPSLKGLGCKRIIICVAEKDPLMERGKAYYEAVKKSGWEGDIELIQSDGEEHVFHLKNPEGENALQLVNKIVAFVRKND
>g46242.t1
MSSANHSNQQNEPEEAVLVDCAPLFRLYTSGHVQRLLGSATAPPSANSKDVTITSNPHKISARLFLPSRLNPANSSKLPILIYYHGGAFCIESAFSPTYHNFLTKMAEEAGMVVVSVDYRLAPENLLPAAYEDAWVGLEWVFGVGVDEWVRDWGDLERVWVAGDSAGANIAHHMALRAGCTNGAIKLEGMILVHSYFWGSEKMESETCEAGIRAFMEKLWKSLTPPEMQSLDHPTLNPTAEDAPSLKGLGCKRIIICVAEKDILVERGKAYYEAVKKSGWEGDIELVQSNGEEHVFYLTNPEGDNALQLVSKIAAFVRKND
>g52116.t1
MESTTSNPTNEILLDYKSIFNVYKDDSIVRFAGTEFAPPGTDLTTNVTTADITIDPVKNITARVHVPNVVTDASSGESKMLHVLVCDCIDYRLATEHLLPGAYEDSVDAIKWVHSSGSNELLVKYGDVDRLFLGGESAG
>g64147.t1
MAEEAGMVVVSVDYRLAPENLLPAAYEDAWVGMEWVFSVGVDEWVRDWGDLGRVWVAGDSAGANIAHHMALRAGSTNGAIKLEGMILVHSYFWGSEKMESETCKAGIRAFLEKLWKSVTPPEMQSLDHPTLNPMAKDAPSLKGLGCKRIIICVAEKELLVERGKSYYEAVKKSGWEGDIELVQSDGEEHVFHLTNPEGENALQLVSKIVAFVRKND
>g89807.t1
MVSVRGRIAPLQAVHRNPKKSLSNYCQILYSYYSVTSQCTTKSSENKMDSTKEIEHNFPPFFCLYKNGDVHRFMGTSIVPPYTDPASNVLSKDVTINSETGLAARLYIPKPDDAASSKFPVLVYYHGGAFCIESAFSPTYHTFLTHLVEKAPVVVVSVNYRLAPEHKLPIAYDDSWEALQWVMSKGDAWIEKYGDFEKVFLAGDSAGANIAHQMAMRGVGMNIDGLMMIHPYFGKETADPEEKAKRSIFWKIISSTEMDDPAHNPMINGGKGTMEVACRRVIVCVAEKDFLAERGVEYHEKLKGSEWKGEVTFVSTEDEGHVFHLQNPGCDKGLELTDKLIAFIHNQ
>g177150.t1
MDPDTEIKFEYPNSFIVYKSGRIKRFPATTEVVPPSLDQTTGVLSKDVTIDARNNISARLYVRNIRKNNSKKKIPILIYIHGGAFCLYSSATPAYHTFVNSLVSKTDVIVVSVNYRLATENLLPIAYEDAWVAIMWVFGFKPDIWLSKYGDFGQVSIAGDSAGGNIVHQMVLRAEQIKIKFEGMILIDPYFWGEEPIESESTDVIDREFMRELWEVVNIPGVGNDDERINPVAKNAPSLRHVACKRALICIASEDLLVERGRLYFNTLRECGWEGDVDLFESEGEGHDFHLDKPNSEHALELMDRLVSFLDYGRKGEGMNFVYDCWVGIFHVWNRQILPFLSWRSFMLYHTKRWLALEIVYLPGRTYFRVSNIVWRFLFFIVEQQTRS
>g323196.t1
MAGSMRPLDNRSRYPSTKKKRKKILMASNNREVIDEVSNWLRIYSDGTVDRTWTGPPEPLFLLEPVPPHGTPINNVTVHDIPSNNPSFRVYFPETKPEPKTRLPILIHFHGGGFCISHATWYMYHQFYSRLASSIPAMILSPFLPLAPENRLPAAIDVCHDFLMRILSTDGFEDPFMERLKNTADMDRVFLIGDSSGGNLVHQVAAKAGPDLAGAIMLHPGFVRARRSGSEMDRSRESAMLSLEMLDKFLGYALPVGATKDHPITCPMDTELEAVRLPPLLVAVAGRDLIQDTNLEYCEAVRKAGKKVEVVVSEGVGHSFYLNKLEVDMDPVAGRRAQELLLTIKDFVNRH
>g414218.t1
MHTYKGENYKRACILSRSSPISKPTMTTTDSLTEFEECRGVLRVYSDGSIVRSPNPSFPVPIHDDGTVDWKDVQFDPTHNLFLRLYKPRSHSSKLPILFYFHGGGFCIGSRTWPNCQNYCLRLSADLNAVIISPDYRLAPEHRLPAALHDSVTSLQWLRAQATAEEPDPWLADVADFDRVFISGDSAGGTIAHHLAVRYSKADLGPIRVRGYVLLGPFFAGKERTISEAECPTDAFLNLELNDRFWRLSIPEGADLDHPIVNPFGPESVDLKKVEFERMLVVVGQCDLLRDRGVEYGEKLKGWGKPVEVVEFEGQQHGFFTIRPWSEPANELMMVFKKFIDHRRPLQRRNMTLPVCQLQ
>g477567.t1
MNQTTTRSNWSCTYKVRNIILIFPVVELAELERRQRDFYTTRNSKYRAVTFLFIIKNQTYPCSTRAKMSSASHTDQQHESEEAVLVECAPLFRLYTSGRVQRLLGTATAPPPVNSKDVTITSNPHKISARLFLPSRLNPTNSSKLPILIYYHGGAFCIESAFSPTYHNFLTKMVEEAGMVVVSVDYRLAPENLLPAAYEDAWVGLEWVFGVGVDEWVRDWGDLGRVWVAGDSAGANIAHHMALRAGSTDGVVKLEGMILVHSCLWGSKKLESETCEAEVRAWMEKLWKSIAPPEMQSLDHRMLNPMAEDAPSLKGLGCKRIIICVAEKDPLMERGKAYYEAVKKSGWEGDIELVQSDGEGHVFHLTNPEGENALQLVSKIVAFVRKND
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University