Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Davidia involucrata
Species name
Davidia involucrata is a species of eudicot in the family Nyssaceae.
Species info
Gene sequence info
Davidia_involucrata.COMT.fa
Download
>Dinv42100.t1
MKSLKVFSISLLQKFLGNQRSASTLEKDTISFMPFFTSGNNEYRKAWVLHDWADDECIQILRKCREAIPKDKGKVIIVEAVVEEEEGDKLNPPGNTPRYCNACEKDVAGFVYHCKTCGFDLHPCCVKLPRVLDDGEVKLHLHRKVSEPCHRCGRKGRSWSYRSTCKKYNLHVACVMEMLVENWHEIYVGRGNSRSALESRPSSIPSLKGTLETHLIHRKSKDRVQKCCEMAALAVQFVISALLGDPTTLIAGLVGSLMSK
>Dinv41702.t1
MDSAEKQSKPASIEEEDESCVYAMQLSLSHVLPMVLNAATELDLFDIIARSGPDAQISASEIVSKLPTQNPDAPAMLDRMLRLLGSYSLLSCSLHTLEDGSVDRRYGLSPAGKFFVQTQDGPSLASVVSLANHPAPREVRYNLKDAILEGGNQFEKVHGMSIFQYMNIDPTLNKVFNRAMADISTSVMKKILEVYKGFEGLKSLVDVGGGIGMSLNMIISMYPSIKGINFDLPHVIQSAPSYSGIEHVGGDMLVSIPKGDAIMIKSACHNWSDGHCVKILNNCYEALPENGKAIIVDIVLPMVPESSNAAKYGTQLDNLMLLEPGGKERTEKDFEALCKASKFSNLQIVCRAYALSVIEFYK
>Dinv41703.t1
MGSIEKQYSNYIEEEEDESCVHALQLTLSQVLPMVLNAANELEIFDIIAGAGGPDSDAQISASEIASKLPTQNPDAPAMLDRMLRLLGTHSLLSCSLHTLEDGTVQRRYALSPVGKFFVQNQDGSSLASLVSLGNHRAYTEVTYNLKDAILEGGNQFEKVHGMSIFQYMNIDPTLNKVFNRAMADISTSVMKKILEVYKGFEGLKSLVDVGGGIGMSLNMIISMYPSIKGINFDLPHVIQSAPSYPGIEHVGGDMLVSIPKGDAIMIKSACHNWSDGHCVKILNNCYEALPENGKAIIVDIVLPMVPESSNAAKYGTQLDNLMLLEPGGKERTEKDFEALCKASKFSNLQIVCRAYALSVIEFYK
>Dinv29207.t1
MGSRSEKQTSPGEEAEEEACLFAMQLASASVLPMVLKSAIELDLLETMAKAGPGAYISPSELAAQLPIIKNPDAPVMLDRILRLLASYSVLNCTLRNLPDGRVERLYGLAPVSKFLTRNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTITMKKILETYNGFDGLASVVDVGGGTGATLNMILSKYPAIKGINFDLPHVIEDAPPYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDEHCLKFLKNCYEALADKGKVIVAECILPVAPDTRLATKNVIHIDVIMLAHNPGGKERTEKEFEALAKGAGFEGFRVMCCAYNTWVMEFLKKV
>Dinv11989.t1
MNSKEGLDYLSAWGLGGLIATQMAIRAAIELNVFNIISDSGPEAQLSSAEIVSKIPTTNPNAATALDRILRMLSAKSLLSTSLKPCPNGVERTYGLTMETRILVTNADGVSLAPAMLMVTEREFVESFYTLKNVVLEPGCSPFQKAFGVNFFEYVAKDPRVSRMFNESMACHSKMAFDMVFKVYTGFQEVKELMDVGGGNGTLLGRIVSNYPHIHGINFDLPHVIADAPKFPGVEHVAGDMFELLPTAQTILLKSVLHDWDDHHCITLLKNCWKALPANGKVIVIESAIPEVSENDAELQNVIVMDVCMMVVAGGRERPTTEFDNLAKAAGFAETMIFHITQGIHVMEFVKKIIE
>Dinv11990.t1
MESKEEGLDYLSAWGLGGLIATQMVIRAAIELNVFNIISDSGPEAQLSSAEVVSKIPTTNPNAATALDRMLRMLSAKSLLLTSTRPCPTGVERTYGLSMEARTLVTNADGVSFAPTTLLTSERALVESLYMLKNVVLEPECSPIFQKSQGMNFFEYAAKDQRVSRVFNESMACHSKMTLDKVFRVYTGFEEVKELMDVGGGNGTSVGRIVSIYPHIHGINFDLPHVIADALKFPGVEHVAGDMFELLPNAQTILLKSVLHDWDDNQCITIFRNCWKALPANGKVIVIESAIPEESDNDAEFQNVIVMDVFMMVVSGGKERSTAEFDDLAKAAGFAETKIFHIGQGNHVMEFIKRINIE
>Dinv17295.t1
MGSTSEVQSNPAEAEEEACLFAMQLASASVLPMVLKSAIELDLLETIAKAGPGAYVSPSELATQLPTQNPDAPVMLDRILRLLASYSVLDCTLRNLPDGRVQRLYGLAPVCKFLTRNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTITMKKILETYKGFEGLTSVVDVGGGTGATLNMIVSKHPTIKGINFDLPHVIEDAPSYPGVEHAGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYEALPNNGKVIVAECILPVSPDTRLATRNVIHIDVIMLAHNPGGKERTQKEFEALAKGAGFEGFRVNVLCL
>Dinv08011.t2
MSSTENQQVVSPSIEEEDEACAYAMQLSLSHILHMVLNAAVELELFDIIAQAGSGAHISSSEIVSQLPARNPDAPSVLDRMLCLLASYSLLTCSLRTHQDGTVERLYGLAPAGKFFVKNQGGRSLASMLPFTCYQPTWNAWFHLKDAILEDGNLFNKVCGMHVFQFMNADPTFNSLFNRSMADISNITMKKLLETYKGFEGLASLVDVAGGTGTSVNMIISMYPSIKGINFDLPHVIQSAPSYPGIEHVGGDMFVSIPKAEAIMVKVSLDTKIELEIHVLGGCEKKFHMTMGGSRP
>Dinv07210.t1
MSTTTQTNSKPTQEHEEEEMGKLAVRLANAVVLPMVLKSALELNLIDVISAAGDGAYLSPSQIAAQLPTRNPDAPVLLDRMLRLLASYDVLKCSLQTGENGEVQRLYGVGPICKFLIKSQDGGGSVGPLFLLHHDKVFMESWYHLNDVILEGGIPFNRAYGMTAFEYPGTDQRFNRVFNQAMSNHTTLIIKKILDIYKGFEGLKVLVDVGGGIGVTLNIITTKYPLIKGINYDLPHVLADAPPYSGVEHVGGDFFVSVPKGDAIFMKWILHDWSDAHCLKLLKNCWEALPNSGKVIIVESILPEAPESSVSSHIVFEQDLLMLAQNPGGKERTQKEYEALAVKSGFSGCEVICCAYNSWVMEFHKRANP
>Dinv28242.t1
MDPQPELATPVSYVCGENKKIIASCEEEEEEEEEDRQWQYATQLACSSVLPMVLKAAIELGLLDIIERAGPGALLSPTEIASHLPLSTNKYNNPEYDVDRILRLLATHSILTSTTPHHHEYDGPQVHRLYGLAPVSKYFIRNQDGVSLAPLLELIQGKVMIDMWYHMKDAVIEGGLPFNRAYGMNASEYAGKDVKYLELFKTSMREYNFMFMRMILGKYKGFQSLKSMVDVGGGDGTILNMIVSSYPTIKGINFDLPPIIHKSPSYPGIEHIAGDMFVSIPKGDAIFMKWILHGWDDEHCLKILKNCCEALPDHGKVIVVDLVVPEAPETSIPVQSVLQFDLFMMNMNPGGKERTQKEFEILAKAAGFSSIRVEDELEEDDWLRTPFCLSSWSL
>Dinv22987.t1
MAIGGRGCDAVGAVVEVGAGKAVAGSGVWRLIVAVGELGGARLEVLGGRLEVLGGRKWFSCRRLRGLWEERTVDGWAAGTEVFEGLTSLVDVGGGTETVARARAIAKMFPHLKCTVFDLPHVIANLQVSENLDFVGGDMFESIPPANAILLK
>Dinv32208.t1
MVSRALVTNTDGVSLAQGMLFSSEREVVESLYMIKNAVLEPECLPFEKANGMSFFEYVAKDPRSSRLFNHNMEWLSKILFDKVFKVYRGFEEVKELMDVGGGNGTSLGKIVSIHPHIHGINFDMLHVVADAHKFPGVKHVAGDMFESLPNAQTILLKSVLHDWDDDRCIKILENCWKALPANGKVIVVEFAIPQELGNDAEVALVMDFYMMVALGGKERSTTEFDDLEKAAGFAETQIFPIAQGLHVMEFIKTTFD
>Dinv34261.t1
MGSSAKTSLYHEDGDEEEQSSYAMQLVNSSVLPMVMQAAVELDLLEIIAKAGPGAQLSPSEIASQMPTTTRCRSNPEAPAMLDRILLLLASYSVLTCSVVDAEQRLYGLAPVAKYFVRNEDGVSLGPLMALLQDKVFIDSWYALKDAVVEGGIPFNKVHGTHAFDYPARDPRFNEVFNKAMINHTTIVIKRILESYKGFEHLKQIVDVGGGLGVTLNMITSKYPTIRGINFDLPHVIQHAPRFPGVEHVGGDMFESVPKGDAIFMKWILHDWSDDHCLKLLKNCYKAVPDNGKVIVVEAILPVIPDTSTAVKGICQIDLIMMTQNPGGKERTQKEFLALASGAGFAGIRLECFACNFWVMEFYK
>Dinv37352.t1
MPSFRLNVADTIWQGGSNTPLSASEILSRILPSGDPENLQRILRMLTSYGVFTEHLNNDGSKRRYSLTEIGKTLVADDKGLSVCTLRAPTPPRSTHESMDAGARGCGGPNIRAVREGQR
>Dinv37351.t1
MSGVSVPFMKAILDGYDGFRGVERLVDVGGSAGDCLRMILQKNPNVKEGVNFDLPEVVARAPNIPRVTHIGGDMFKSIPTGDAIFMKWVLTTWTDDECKLIMKNCHGALPVGGKMIACEPVLPEQSDDSHRTRALLEGDIFVMTVYRAKGKHRTEDEYRQLGLSAGFPHFRSICIDYFYTVLEFQK
MKSLKVFSISLLQKFLGNQRSASTLEKDTISFMPFFTSGNNEYRKAWVLHDWADDECIQILRKCREAIPKDKGKVIIVEAVVEEEEGDKLNPPGNTPRYCNACEKDVAGFVYHCKTCGFDLHPCCVKLPRVLDDGEVKLHLHRKVSEPCHRCGRKGRSWSYRSTCKKYNLHVACVMEMLVENWHEIYVGRGNSRSALESRPSSIPSLKGTLETHLIHRKSKDRVQKCCEMAALAVQFVISALLGDPTTLIAGLVGSLMSK
>Dinv41702.t1
MDSAEKQSKPASIEEEDESCVYAMQLSLSHVLPMVLNAATELDLFDIIARSGPDAQISASEIVSKLPTQNPDAPAMLDRMLRLLGSYSLLSCSLHTLEDGSVDRRYGLSPAGKFFVQTQDGPSLASVVSLANHPAPREVRYNLKDAILEGGNQFEKVHGMSIFQYMNIDPTLNKVFNRAMADISTSVMKKILEVYKGFEGLKSLVDVGGGIGMSLNMIISMYPSIKGINFDLPHVIQSAPSYSGIEHVGGDMLVSIPKGDAIMIKSACHNWSDGHCVKILNNCYEALPENGKAIIVDIVLPMVPESSNAAKYGTQLDNLMLLEPGGKERTEKDFEALCKASKFSNLQIVCRAYALSVIEFYK
>Dinv41703.t1
MGSIEKQYSNYIEEEEDESCVHALQLTLSQVLPMVLNAANELEIFDIIAGAGGPDSDAQISASEIASKLPTQNPDAPAMLDRMLRLLGTHSLLSCSLHTLEDGTVQRRYALSPVGKFFVQNQDGSSLASLVSLGNHRAYTEVTYNLKDAILEGGNQFEKVHGMSIFQYMNIDPTLNKVFNRAMADISTSVMKKILEVYKGFEGLKSLVDVGGGIGMSLNMIISMYPSIKGINFDLPHVIQSAPSYPGIEHVGGDMLVSIPKGDAIMIKSACHNWSDGHCVKILNNCYEALPENGKAIIVDIVLPMVPESSNAAKYGTQLDNLMLLEPGGKERTEKDFEALCKASKFSNLQIVCRAYALSVIEFYK
>Dinv29207.t1
MGSRSEKQTSPGEEAEEEACLFAMQLASASVLPMVLKSAIELDLLETMAKAGPGAYISPSELAAQLPIIKNPDAPVMLDRILRLLASYSVLNCTLRNLPDGRVERLYGLAPVSKFLTRNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTITMKKILETYNGFDGLASVVDVGGGTGATLNMILSKYPAIKGINFDLPHVIEDAPPYPGVEHVGGDMFVSVPKADAIFMKWICHDWSDEHCLKFLKNCYEALADKGKVIVAECILPVAPDTRLATKNVIHIDVIMLAHNPGGKERTEKEFEALAKGAGFEGFRVMCCAYNTWVMEFLKKV
>Dinv11989.t1
MNSKEGLDYLSAWGLGGLIATQMAIRAAIELNVFNIISDSGPEAQLSSAEIVSKIPTTNPNAATALDRILRMLSAKSLLSTSLKPCPNGVERTYGLTMETRILVTNADGVSLAPAMLMVTEREFVESFYTLKNVVLEPGCSPFQKAFGVNFFEYVAKDPRVSRMFNESMACHSKMAFDMVFKVYTGFQEVKELMDVGGGNGTLLGRIVSNYPHIHGINFDLPHVIADAPKFPGVEHVAGDMFELLPTAQTILLKSVLHDWDDHHCITLLKNCWKALPANGKVIVIESAIPEVSENDAELQNVIVMDVCMMVVAGGRERPTTEFDNLAKAAGFAETMIFHITQGIHVMEFVKKIIE
>Dinv11990.t1
MESKEEGLDYLSAWGLGGLIATQMVIRAAIELNVFNIISDSGPEAQLSSAEVVSKIPTTNPNAATALDRMLRMLSAKSLLLTSTRPCPTGVERTYGLSMEARTLVTNADGVSFAPTTLLTSERALVESLYMLKNVVLEPECSPIFQKSQGMNFFEYAAKDQRVSRVFNESMACHSKMTLDKVFRVYTGFEEVKELMDVGGGNGTSVGRIVSIYPHIHGINFDLPHVIADALKFPGVEHVAGDMFELLPNAQTILLKSVLHDWDDNQCITIFRNCWKALPANGKVIVIESAIPEESDNDAEFQNVIVMDVFMMVVSGGKERSTAEFDDLAKAAGFAETKIFHIGQGNHVMEFIKRINIE
>Dinv17295.t1
MGSTSEVQSNPAEAEEEACLFAMQLASASVLPMVLKSAIELDLLETIAKAGPGAYVSPSELATQLPTQNPDAPVMLDRILRLLASYSVLDCTLRNLPDGRVQRLYGLAPVCKFLTRNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTITMKKILETYKGFEGLTSVVDVGGGTGATLNMIVSKHPTIKGINFDLPHVIEDAPSYPGVEHAGGDMFVSVPKGDAIFMKWICHDWSDEHCLKFLKNCYEALPNNGKVIVAECILPVSPDTRLATRNVIHIDVIMLAHNPGGKERTQKEFEALAKGAGFEGFRVNVLCL
>Dinv08011.t2
MSSTENQQVVSPSIEEEDEACAYAMQLSLSHILHMVLNAAVELELFDIIAQAGSGAHISSSEIVSQLPARNPDAPSVLDRMLCLLASYSLLTCSLRTHQDGTVERLYGLAPAGKFFVKNQGGRSLASMLPFTCYQPTWNAWFHLKDAILEDGNLFNKVCGMHVFQFMNADPTFNSLFNRSMADISNITMKKLLETYKGFEGLASLVDVAGGTGTSVNMIISMYPSIKGINFDLPHVIQSAPSYPGIEHVGGDMFVSIPKAEAIMVKVSLDTKIELEIHVLGGCEKKFHMTMGGSRP
>Dinv07210.t1
MSTTTQTNSKPTQEHEEEEMGKLAVRLANAVVLPMVLKSALELNLIDVISAAGDGAYLSPSQIAAQLPTRNPDAPVLLDRMLRLLASYDVLKCSLQTGENGEVQRLYGVGPICKFLIKSQDGGGSVGPLFLLHHDKVFMESWYHLNDVILEGGIPFNRAYGMTAFEYPGTDQRFNRVFNQAMSNHTTLIIKKILDIYKGFEGLKVLVDVGGGIGVTLNIITTKYPLIKGINYDLPHVLADAPPYSGVEHVGGDFFVSVPKGDAIFMKWILHDWSDAHCLKLLKNCWEALPNSGKVIIVESILPEAPESSVSSHIVFEQDLLMLAQNPGGKERTQKEYEALAVKSGFSGCEVICCAYNSWVMEFHKRANP
>Dinv28242.t1
MDPQPELATPVSYVCGENKKIIASCEEEEEEEEEDRQWQYATQLACSSVLPMVLKAAIELGLLDIIERAGPGALLSPTEIASHLPLSTNKYNNPEYDVDRILRLLATHSILTSTTPHHHEYDGPQVHRLYGLAPVSKYFIRNQDGVSLAPLLELIQGKVMIDMWYHMKDAVIEGGLPFNRAYGMNASEYAGKDVKYLELFKTSMREYNFMFMRMILGKYKGFQSLKSMVDVGGGDGTILNMIVSSYPTIKGINFDLPPIIHKSPSYPGIEHIAGDMFVSIPKGDAIFMKWILHGWDDEHCLKILKNCCEALPDHGKVIVVDLVVPEAPETSIPVQSVLQFDLFMMNMNPGGKERTQKEFEILAKAAGFSSIRVEDELEEDDWLRTPFCLSSWSL
>Dinv22987.t1
MAIGGRGCDAVGAVVEVGAGKAVAGSGVWRLIVAVGELGGARLEVLGGRLEVLGGRKWFSCRRLRGLWEERTVDGWAAGTEVFEGLTSLVDVGGGTETVARARAIAKMFPHLKCTVFDLPHVIANLQVSENLDFVGGDMFESIPPANAILLK
>Dinv32208.t1
MVSRALVTNTDGVSLAQGMLFSSEREVVESLYMIKNAVLEPECLPFEKANGMSFFEYVAKDPRSSRLFNHNMEWLSKILFDKVFKVYRGFEEVKELMDVGGGNGTSLGKIVSIHPHIHGINFDMLHVVADAHKFPGVKHVAGDMFESLPNAQTILLKSVLHDWDDDRCIKILENCWKALPANGKVIVVEFAIPQELGNDAEVALVMDFYMMVALGGKERSTTEFDDLEKAAGFAETQIFPIAQGLHVMEFIKTTFD
>Dinv34261.t1
MGSSAKTSLYHEDGDEEEQSSYAMQLVNSSVLPMVMQAAVELDLLEIIAKAGPGAQLSPSEIASQMPTTTRCRSNPEAPAMLDRILLLLASYSVLTCSVVDAEQRLYGLAPVAKYFVRNEDGVSLGPLMALLQDKVFIDSWYALKDAVVEGGIPFNKVHGTHAFDYPARDPRFNEVFNKAMINHTTIVIKRILESYKGFEHLKQIVDVGGGLGVTLNMITSKYPTIRGINFDLPHVIQHAPRFPGVEHVGGDMFESVPKGDAIFMKWILHDWSDDHCLKLLKNCYKAVPDNGKVIVVEAILPVIPDTSTAVKGICQIDLIMMTQNPGGKERTQKEFLALASGAGFAGIRLECFACNFWVMEFYK
>Dinv37352.t1
MPSFRLNVADTIWQGGSNTPLSASEILSRILPSGDPENLQRILRMLTSYGVFTEHLNNDGSKRRYSLTEIGKTLVADDKGLSVCTLRAPTPPRSTHESMDAGARGCGGPNIRAVREGQR
>Dinv37351.t1
MSGVSVPFMKAILDGYDGFRGVERLVDVGGSAGDCLRMILQKNPNVKEGVNFDLPEVVARAPNIPRVTHIGGDMFKSIPTGDAIFMKWVLTTWTDDECKLIMKNCHGALPVGGKMIACEPVLPEQSDDSHRTRALLEGDIFVMTVYRAKGKHRTEDEYRQLGLSAGFPHFRSICIDYFYTVLEFQK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University