Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Daucus carota
Species name
Carrot (Daucus carota) is a species of eudicot in the family Apiaceae (carrot family).
Species info
Gene sequence info
Daucus_carota.4CL.fa
Download
>rna-XM_017398507.1
MPSPSDSPEAIDPNSGYESATRTFHSLRPRVPLPPSTQPLSITQYASSLLHSTASFSPETTAYLIDAASSTRLSYSQFLEQSRRLSAWLRSRFPSLSSQKVALIVSPPSLHVPVLYFSLISLNVIVSPANPLSTPSELEHLVKLCDPVIAFVTSSVSSVRHLPALPTVMIDSPEFLSMLNTEKSYEMPKQVAVSQSDTAAILYSSGTTGRVKGVELTHRNLITVIANLYHNKRASLEDEELSVALFTLPLFHVFGFFMLIRGFALGETLVLMERFDFVKMLEAVEKYKVTYMPVSPPIVVAMAKSDVVKNYDLSSLRLLGSGGAALGKETSERFTARFPNVEISQGYGMTETGGAATTMSDPEESKEYGSGGRLAANMQGKIVDPVTGQALPPGKQGELWLRGPNIMKGYVGDNVATAETLTSDGWLKTGDLCYFDSKGFLYIVDRLKELIKYKAYQVPPAELEHIIHSIPGVADVAVIPYPDEDAGQIPMAYVVRSPGSNISESQIKDFVAAQVSPYKKVRRVAFINSIPKSPAGKILRRELVNHALSGASARL
>rna-XM_017398405.1
MEKSGYGRDGIFRSLRPPLTLPKDPNLSMISFLLRNTASSATKPALIDSNSGETLTFSGLKTAVTNLSSNLHQMGINKNDVVLIFAPNSIEFPVAFLGIIAAGAIATTANPAYTVPEVEKQVKDCDPKLIFTVPELLGKVKKFNLPVVLMGCQEQDGFSEFKGESKITLFTDLVKNNGVVVNLPKVGGNDTAALLYSSGTTGISKGVILSHRNFIAASLMLNSDQDLLGEVDSVYMCVVPMFHVFGLALITFGQLQRGSTVLAVPKFDFEMILRAIEKFRVTHLWIVPPVVLALAKQSLVKKYDLSSLKQIGSGAAPLGKDLMQECAKNFPRALVIQGYGMTETCGIVSVENQLGGPRHTGSAGLLVPGVESQIVSVDTQKPLPPNQLGEIWVRGPNMMQGYFKNPQATNLTIDAQGWVHTGDLGYFDDEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHSEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVKNFIAKQVAPFKRLRRITFVNSVPKSASGKILRRELIEKVRAKM
>rna-XM_017403321.1
MGDCAAPKQEIIFRSKLPDIYIPKHLPLHSYCFENISKVSDKACLINGATGETFSYAQVELISRRVASGLNKAGVHQGDTIMILLPNTPEYFFAFLGASYRGAVSTMANPFFTSPEVIKQLKASQAKLIITQACYVEKVKEYAAENNITVVCIDEAPRDCLHFTTLMEADEAEMPEVVIDSDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMICILPLFHIYSLNAVLCCGLRAGATILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDNYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPYEIKSGACGTVVRNAEMKIVDPETHASLPRNQSGEICIRGDQIMKGYLNDPESTKTTIDEEGWLHTGDIGFIDEDDELFIVDRLKEIIKYKGFQVAPAEIEALLLTHPTISDAAVVPMIDEKAGEVPVAFVVRLNGSTTTEEEIKQFVSKQVVFYKRVFRVFFVDAIPKSPSGKILRKELRARIASGDLPK
>rna-XM_017359927.1
METKTNKKQDIIFRSKLPDIDIPKHLPLHSYCFENIAKFSDRPCLINGATDQIYTYSDVQLISKKVSSGLNKLGIHQGDTIMLLLPNSPEFVFAFLGASYRGAISTMANPFFTSAEVIKQVKASNAKLIITQANYVDKIKKYASENNLKVMCVDAPPEGCLHFSELSQADENDMPEVEISPDDAVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYMHSEDVMLCCLPLFHIYSLNSVLLCGLRAGTAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDNYDLSSVRTVMSGAAPLGKDLEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTSVSLPRNQRGEICIRGDQIMKGYLNDPESTERTIDKEGWLHTGDIGYIDDDDELFIVDRLKEIIKYKGFQVAPAELEAMLLTHPNISDAAVVSMIDEKAGEVPVAFVVQSNGSTTTEDEVKQFISKQVVFYKRIYRVFFVDSIPKSPAGKILRKDLRARLAAGDLPQTK
>rna-XM_017366636.1
MASNHEEHIFRSRYAAVPIPDNMTLPEFVLHDVELYAEKVAFVDAFSGKEYTYGEVSRDVKRFAKALRSLGLRRGHVVMVVLPNIVEYPIVALGIMAAGGVVSGANPASHVSEIKKQAESADAKSIVTDATTYEKVKSLGLPNVIVGEKRVEGSIYWNELLDAAERASDSIMNEKVQQSDICALPFSSGTTGLSKGVMLSHRNLVANLCSTLFSVGPELVGNVTTLGLIPFFHIYGLTGICCAALRNKGKVVVMNRYELRTFLNALIKYEVTFAPIVPPIILGLVKNPIVDEFDLSKLKLRSIMTAAAPLAPEILAEFEKKFPDVVVQEAYGMTEHSCITLTHGDPNKGHGIAKKHSVGFILPNLEVKFIDPDTNHSLPQNTPGEVCVRSQCVMEGYYKNEYETAHAIDKDGWLHTGDIGYIDDDGDVFIVDRIKELIKFKGFQVAPAELEGILLTHPSVEDAAVVGLPDEEAGEIPGACVVMNKEAKDSEEEVMSFVASNVAHYKKIRVLQFVDSIPKSSSGKIMRRVIKDKMIQTIKTSCPTTTRKGAF
MPSPSDSPEAIDPNSGYESATRTFHSLRPRVPLPPSTQPLSITQYASSLLHSTASFSPETTAYLIDAASSTRLSYSQFLEQSRRLSAWLRSRFPSLSSQKVALIVSPPSLHVPVLYFSLISLNVIVSPANPLSTPSELEHLVKLCDPVIAFVTSSVSSVRHLPALPTVMIDSPEFLSMLNTEKSYEMPKQVAVSQSDTAAILYSSGTTGRVKGVELTHRNLITVIANLYHNKRASLEDEELSVALFTLPLFHVFGFFMLIRGFALGETLVLMERFDFVKMLEAVEKYKVTYMPVSPPIVVAMAKSDVVKNYDLSSLRLLGSGGAALGKETSERFTARFPNVEISQGYGMTETGGAATTMSDPEESKEYGSGGRLAANMQGKIVDPVTGQALPPGKQGELWLRGPNIMKGYVGDNVATAETLTSDGWLKTGDLCYFDSKGFLYIVDRLKELIKYKAYQVPPAELEHIIHSIPGVADVAVIPYPDEDAGQIPMAYVVRSPGSNISESQIKDFVAAQVSPYKKVRRVAFINSIPKSPAGKILRRELVNHALSGASARL
>rna-XM_017398405.1
MEKSGYGRDGIFRSLRPPLTLPKDPNLSMISFLLRNTASSATKPALIDSNSGETLTFSGLKTAVTNLSSNLHQMGINKNDVVLIFAPNSIEFPVAFLGIIAAGAIATTANPAYTVPEVEKQVKDCDPKLIFTVPELLGKVKKFNLPVVLMGCQEQDGFSEFKGESKITLFTDLVKNNGVVVNLPKVGGNDTAALLYSSGTTGISKGVILSHRNFIAASLMLNSDQDLLGEVDSVYMCVVPMFHVFGLALITFGQLQRGSTVLAVPKFDFEMILRAIEKFRVTHLWIVPPVVLALAKQSLVKKYDLSSLKQIGSGAAPLGKDLMQECAKNFPRALVIQGYGMTETCGIVSVENQLGGPRHTGSAGLLVPGVESQIVSVDTQKPLPPNQLGEIWVRGPNMMQGYFKNPQATNLTIDAQGWVHTGDLGYFDDEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHSEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVKNFIAKQVAPFKRLRRITFVNSVPKSASGKILRRELIEKVRAKM
>rna-XM_017403321.1
MGDCAAPKQEIIFRSKLPDIYIPKHLPLHSYCFENISKVSDKACLINGATGETFSYAQVELISRRVASGLNKAGVHQGDTIMILLPNTPEYFFAFLGASYRGAVSTMANPFFTSPEVIKQLKASQAKLIITQACYVEKVKEYAAENNITVVCIDEAPRDCLHFTTLMEADEAEMPEVVIDSDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYIHSEDVMICILPLFHIYSLNAVLCCGLRAGATILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDNYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPYEIKSGACGTVVRNAEMKIVDPETHASLPRNQSGEICIRGDQIMKGYLNDPESTKTTIDEEGWLHTGDIGFIDEDDELFIVDRLKEIIKYKGFQVAPAEIEALLLTHPTISDAAVVPMIDEKAGEVPVAFVVRLNGSTTTEEEIKQFVSKQVVFYKRVFRVFFVDAIPKSPSGKILRKELRARIASGDLPK
>rna-XM_017359927.1
METKTNKKQDIIFRSKLPDIDIPKHLPLHSYCFENIAKFSDRPCLINGATDQIYTYSDVQLISKKVSSGLNKLGIHQGDTIMLLLPNSPEFVFAFLGASYRGAISTMANPFFTSAEVIKQVKASNAKLIITQANYVDKIKKYASENNLKVMCVDAPPEGCLHFSELSQADENDMPEVEISPDDAVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYMHSEDVMLCCLPLFHIYSLNSVLLCGLRAGTAILIMQKFDIVPFLELIQKYKVTIGPFVPPIVLAIAKSPVVDNYDLSSVRTVMSGAAPLGKDLEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPDTSVSLPRNQRGEICIRGDQIMKGYLNDPESTERTIDKEGWLHTGDIGYIDDDDELFIVDRLKEIIKYKGFQVAPAELEAMLLTHPNISDAAVVSMIDEKAGEVPVAFVVQSNGSTTTEDEVKQFISKQVVFYKRIYRVFFVDSIPKSPAGKILRKDLRARLAAGDLPQTK
>rna-XM_017366636.1
MASNHEEHIFRSRYAAVPIPDNMTLPEFVLHDVELYAEKVAFVDAFSGKEYTYGEVSRDVKRFAKALRSLGLRRGHVVMVVLPNIVEYPIVALGIMAAGGVVSGANPASHVSEIKKQAESADAKSIVTDATTYEKVKSLGLPNVIVGEKRVEGSIYWNELLDAAERASDSIMNEKVQQSDICALPFSSGTTGLSKGVMLSHRNLVANLCSTLFSVGPELVGNVTTLGLIPFFHIYGLTGICCAALRNKGKVVVMNRYELRTFLNALIKYEVTFAPIVPPIILGLVKNPIVDEFDLSKLKLRSIMTAAAPLAPEILAEFEKKFPDVVVQEAYGMTEHSCITLTHGDPNKGHGIAKKHSVGFILPNLEVKFIDPDTNHSLPQNTPGEVCVRSQCVMEGYYKNEYETAHAIDKDGWLHTGDIGYIDDDGDVFIVDRIKELIKFKGFQVAPAELEGILLTHPSVEDAAVVGLPDEEAGEIPGACVVMNKEAKDSEEEVMSFVASNVAHYKKIRVLQFVDSIPKSSSGKIMRRVIKDKMIQTIKTSCPTTTRKGAF
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University