Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Datisca glomerata
Species name
Datisca glomerata is a species of eudicot in the family Datiscaceae.
Species info
Gene sequence info
Datisca_glomerata.COMT.fa
Download
>Datgl144S02481
MAMKATVELGIFEIIKGAGEGAMLSSSQIASHLTNFNNSEEATLLLDRIHGLLVSHSILVSSVSVTTTHNLHKDEEEEDGHERVVRQRQRLYGLTPLSTYFEPNKDGVSFVPLLCLS
>Datgl993S36941
MASSAETQSTISTRTHDEEDNEQQHFAYATQLVNLSVLPMALQSAFDLDIFEIIAKAGPAANLSAVEIAAQMPTKNPDAPMMIDRILRLLVSHSVLDCSLGGGDHGDFNRVYSLNPVSKYFVRNEDGVSLGPVLALIQDKIFLESWSELKSSVLEGGIPFNKVHGSHAFEYPGKDPRFNQVFNTAMFNHATVVVKKMLQSYKGFQNLNKVVDVGGGFGVTLNMIISKYPHIKGINFDLPHVIQHAPSYPGVEHVGGDMFESVPEGDAIFMKWILHDWSDEHCLKLLKNSYRATPDDGKVIVMEAVLPAMPERTAEFRGTSEIDVLMMTQNPGGKERTKEEFMALATGAGFSGIRYESFACNFWIMEFFK
>Datgl27372S26385
MGSATETQITPTLVSDEEANLFAMQLVSASVLPMVLKTAIELDLLEIISKAGHGTLLSPSDIAAHLPTRNAEAGTVLDRILRLLASYSILTYSLRTLPDGRVERLYGLAPVCKYLTKNEDGVSLAPLCLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMSDHSTVTMKKILETYKGFEGLNSVVDVGGGTGAVLNMIVSKYPSIKGINFDLPHVVEDAPPYSGVEHVGGDMFVSVPNGDAIFMKWICHDWSDQHCLKFLKNCYDALPENGKVIVAECILPVAPDTSLSTKGVIHIDIIMLAHNPGGKERTEKEFEALAKGAGFQGFKVECNAFNTYVMEFLKKA
>Datgl318S08195
MGEETRFKSLFHQAMISDSKLIASVVVNEFRQVFEGIISVIDVDGGTGAMALTISEVFPHINCTVLDLPHVVANLQATKNLNYVAGDMFQVIPPANAVVLLKLN
>Datgl855S35631
MEEETAESRNRARLVILELANMISVPMSLNAIVRLNIPDAIWQGGSNTPLSASQILSRVLRSGGDPDNLQRILRMLTSYGVFEEHLNRHSSERTYSLTNVGKTLVTDSDGLSYAPYVLQHHQEELMRAWTLVHEAVVDPTTEPFVKANGEAAYAHYGKKPEMNELMQRAMSGVSVPFMKAILNGYDGFEGIERLVDVGGSAGDCLRMILHKHPNVKEGINFDLPEVVAKAPCIPGVTHVGGDMFKSIPNGDAIFTKWVLTTWTDEECKVIMENCYKSLPVGGKLIACEPVLPHESDDSHRTRALLEGDIFVMTIYRAKGKHRTENEFRQLGLSAGFPNFRAFYIDYFYSVLEFQK
>Datgl2014S23986
MEAQKSPDYISAWGMSKYIGIHMALRTALELNVFDIIAKSGLHSHLTPTQIISQIPTTNPHASIALDRLLRFLSANSLLSVSQTPTENERAYGLTEETRCLVTNENGMSSAPMVLLSSEKEIVESIYVLKNVVLEPNYLPFYKTHGVSFFEYVSKKPRLNRLFNETMASSAKLIFEKVFDVYKGFGEVEELMDVGGGIGASLVKILSVYPHIHCINFDLPHVIAEAPKIEGVKHVAGDMYESLPNAQTILLKWILHDWDDEQCKELLKNCWKSLPNEGKVIVLEHILPEIIGNDAESVNIVGMDLYMMVMNPGGRERTIAEYHYLAKSAGFSDTKCFPILQGTHIIEFHKKI
>Datgl1158S18944
MAMKATVELGVFEIIKGAGEGAMLSSSQIASHLTNFNNSKEATLLLDRIHGLLVSHSILVSSVSVTTTHNLHKDEEEEDGHERVVRQRQRLYGLTPLSTYFVPNKDGGSKSWMVAGDFNELLKSNENDGGQPFDFKKARRFRSFIDSCRNGRGGSDFIQERLDRVLG
>Datgl1158S01100
MRRKELLMLNWIKFGRRKSCIDIKELGFSGSKYANGCWKEDEASVSEIIKSFSSDCFKFEHNSDAVKEGGVPFERAHKMKAIQKKMLEDYNGFQGVKSMVDVGGGNDSLLNMIISKYPKIKGINFDFPFIIQNSPSYLGRSLGLGRGLSLGWGRVDSGVMSLTRTPGLVSPIRPNLTPRPISTCIPPKLNSTRLVTPTQTSDLMFSTRPDPTPQPILPRVPFEPDSLTRPD
>Datgl170S22584
MTMSSSVSFGDDKEKDHLSYASQLVNLTVLPMTLQAVFELGIFEIMARAGLGAKLSPVEIAAQMPTKNPDAPQLLDRILRLLVSYYVLDCSLVADDGGKLPRVYSLNSVSKFFVRDEDGFSLGPLMALIQDKVFMDSWSELKGAILEGGVPFNRVHGMHAFEYPGRDARFNQVFNTAMINSTTLIVKKILETYEGFGNLKELIDVGGGLGVTLNLITSRYPSIRAVNFDLPHVIKHAPSYPGVEHVGGDMFESIPKGEAIFMKWILHDWSDDYCLRLLKNCYDAIPDDGKVIVVEAVLPLLPGNSAADKVIYEADLIMLAQNPGGKERTKDEFLALATETGFSGIRFECKVCNLWVMEFFK
>Datgl170S22590
MVHEIHAFDYPGMDARFNHVFNAAMINSTTLIVKRILEAYRGFEHLKELVDVGGGLGVTLNLITSKYPSIKAVNFDLPHVINHAPSYLGVEHVG
>Datgl882S35839
MEKVRMSTQARMQDSVKFSTQRCGGIGVALSLITSKYPKIKGINFDLPHVVRHAPPYPDNGKVIMVEHIMPTFPENTTIAEVKTQLDLLAMTQSQGGKERLQSEMLRLANGAGFNLSRSPVMSTITVWVWMK
MAMKATVELGIFEIIKGAGEGAMLSSSQIASHLTNFNNSEEATLLLDRIHGLLVSHSILVSSVSVTTTHNLHKDEEEEDGHERVVRQRQRLYGLTPLSTYFEPNKDGVSFVPLLCLS
>Datgl993S36941
MASSAETQSTISTRTHDEEDNEQQHFAYATQLVNLSVLPMALQSAFDLDIFEIIAKAGPAANLSAVEIAAQMPTKNPDAPMMIDRILRLLVSHSVLDCSLGGGDHGDFNRVYSLNPVSKYFVRNEDGVSLGPVLALIQDKIFLESWSELKSSVLEGGIPFNKVHGSHAFEYPGKDPRFNQVFNTAMFNHATVVVKKMLQSYKGFQNLNKVVDVGGGFGVTLNMIISKYPHIKGINFDLPHVIQHAPSYPGVEHVGGDMFESVPEGDAIFMKWILHDWSDEHCLKLLKNSYRATPDDGKVIVMEAVLPAMPERTAEFRGTSEIDVLMMTQNPGGKERTKEEFMALATGAGFSGIRYESFACNFWIMEFFK
>Datgl27372S26385
MGSATETQITPTLVSDEEANLFAMQLVSASVLPMVLKTAIELDLLEIISKAGHGTLLSPSDIAAHLPTRNAEAGTVLDRILRLLASYSILTYSLRTLPDGRVERLYGLAPVCKYLTKNEDGVSLAPLCLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNRGMSDHSTVTMKKILETYKGFEGLNSVVDVGGGTGAVLNMIVSKYPSIKGINFDLPHVVEDAPPYSGVEHVGGDMFVSVPNGDAIFMKWICHDWSDQHCLKFLKNCYDALPENGKVIVAECILPVAPDTSLSTKGVIHIDIIMLAHNPGGKERTEKEFEALAKGAGFQGFKVECNAFNTYVMEFLKKA
>Datgl318S08195
MGEETRFKSLFHQAMISDSKLIASVVVNEFRQVFEGIISVIDVDGGTGAMALTISEVFPHINCTVLDLPHVVANLQATKNLNYVAGDMFQVIPPANAVVLLKLN
>Datgl855S35631
MEEETAESRNRARLVILELANMISVPMSLNAIVRLNIPDAIWQGGSNTPLSASQILSRVLRSGGDPDNLQRILRMLTSYGVFEEHLNRHSSERTYSLTNVGKTLVTDSDGLSYAPYVLQHHQEELMRAWTLVHEAVVDPTTEPFVKANGEAAYAHYGKKPEMNELMQRAMSGVSVPFMKAILNGYDGFEGIERLVDVGGSAGDCLRMILHKHPNVKEGINFDLPEVVAKAPCIPGVTHVGGDMFKSIPNGDAIFTKWVLTTWTDEECKVIMENCYKSLPVGGKLIACEPVLPHESDDSHRTRALLEGDIFVMTIYRAKGKHRTENEFRQLGLSAGFPNFRAFYIDYFYSVLEFQK
>Datgl2014S23986
MEAQKSPDYISAWGMSKYIGIHMALRTALELNVFDIIAKSGLHSHLTPTQIISQIPTTNPHASIALDRLLRFLSANSLLSVSQTPTENERAYGLTEETRCLVTNENGMSSAPMVLLSSEKEIVESIYVLKNVVLEPNYLPFYKTHGVSFFEYVSKKPRLNRLFNETMASSAKLIFEKVFDVYKGFGEVEELMDVGGGIGASLVKILSVYPHIHCINFDLPHVIAEAPKIEGVKHVAGDMYESLPNAQTILLKWILHDWDDEQCKELLKNCWKSLPNEGKVIVLEHILPEIIGNDAESVNIVGMDLYMMVMNPGGRERTIAEYHYLAKSAGFSDTKCFPILQGTHIIEFHKKI
>Datgl1158S18944
MAMKATVELGVFEIIKGAGEGAMLSSSQIASHLTNFNNSKEATLLLDRIHGLLVSHSILVSSVSVTTTHNLHKDEEEEDGHERVVRQRQRLYGLTPLSTYFVPNKDGGSKSWMVAGDFNELLKSNENDGGQPFDFKKARRFRSFIDSCRNGRGGSDFIQERLDRVLG
>Datgl1158S01100
MRRKELLMLNWIKFGRRKSCIDIKELGFSGSKYANGCWKEDEASVSEIIKSFSSDCFKFEHNSDAVKEGGVPFERAHKMKAIQKKMLEDYNGFQGVKSMVDVGGGNDSLLNMIISKYPKIKGINFDFPFIIQNSPSYLGRSLGLGRGLSLGWGRVDSGVMSLTRTPGLVSPIRPNLTPRPISTCIPPKLNSTRLVTPTQTSDLMFSTRPDPTPQPILPRVPFEPDSLTRPD
>Datgl170S22584
MTMSSSVSFGDDKEKDHLSYASQLVNLTVLPMTLQAVFELGIFEIMARAGLGAKLSPVEIAAQMPTKNPDAPQLLDRILRLLVSYYVLDCSLVADDGGKLPRVYSLNSVSKFFVRDEDGFSLGPLMALIQDKVFMDSWSELKGAILEGGVPFNRVHGMHAFEYPGRDARFNQVFNTAMINSTTLIVKKILETYEGFGNLKELIDVGGGLGVTLNLITSRYPSIRAVNFDLPHVIKHAPSYPGVEHVGGDMFESIPKGEAIFMKWILHDWSDDYCLRLLKNCYDAIPDDGKVIVVEAVLPLLPGNSAADKVIYEADLIMLAQNPGGKERTKDEFLALATETGFSGIRFECKVCNLWVMEFFK
>Datgl170S22590
MVHEIHAFDYPGMDARFNHVFNAAMINSTTLIVKRILEAYRGFEHLKELVDVGGGLGVTLNLITSKYPSIKAVNFDLPHVINHAPSYLGVEHVG
>Datgl882S35839
MEKVRMSTQARMQDSVKFSTQRCGGIGVALSLITSKYPKIKGINFDLPHVVRHAPPYPDNGKVIMVEHIMPTFPENTTIAEVKTQLDLLAMTQSQGGKERLQSEMLRLANGAGFNLSRSPVMSTITVWVWMK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University