Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Datisca glomerata
Species name
Datisca glomerata is a species of eudicot in the family Datiscaceae.
Species info
Gene sequence info
Datisca_glomerata.CHS.fa
Download
>Datgl1175S19096
MVTVEEVRKTQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTDLKEKFKRMCEKSMIRKRYMYLTEEILKENPNICAYDAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQPKSKITHVVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNDSHLDSLVGQALFGDGASAVIVGADPIPEVEKPIFQLVSASQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLNISDWNSIFWIAHPGGPAILDQVEEKLGLKPEKMSATKHVLSEYGNMSSACVLFILDKMRKKSLEEGHKTTGEGLDWGVLFGFGPGLTVETVVLHSVPV
>Datgl1175S19094
MKRSHEDLSLVVLVVVAAAAAVVLMKMLVTSPLLFSSITIVLPPLLAWLHHCLKGSLCFFKPSNKMVTVEEVRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTDLKEKFKHLCERSTIKKRYMYLTEEILKENPNICAFDAPSLDARQDMVVVEVPKLGKEAASKAIEEWGQPKSKITHVVFCTTSGVDTPGCDYQLTRLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSSCLDNLVGQALFSDGASAVIVGADPIPDIEKPIFQLVSAAQTIVPNSEGAVSIHVREVGFTFHLRKDVPEIISKNIEKFLVEAFQPLNISDWNSIFWIAHPGGPAILDHVEEKLKLKPEKMCATKHVLREYGNMSSACVLFILDQMRKKSLEEGHKTTGEGLDWGVLFGFGPGITVETVVLHSMPI
>Datgl1175S19095
MVTVEEVRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTDLKEKFKRMCEKSMIRKRYMYLTEEILKENPNICAYDAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQPKSKITHVVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNDSHLDSLVGQALFGDGASAVIVGADPIPEVEKPIFQLVSASQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLNISDWNSIFWIAHPGGPAILDQVEEKLGLKPEKMSATKHVLGEYGNMSSACVLFILDKMRKKSLEEGHKTTGEGLDWGVLFGFGPGLTVETVVLHSVPI
>Datgl1175S19093
MVTVEEVRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTDLKEKFKRMCDRSMIKKRYMYLTEEILKENPNICAYDAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQPKSKITHVVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNDSHLDSLVGQALFGDGASAVIVGADPIPEVEKPIFQLVSASQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLNISDWNSIFWIAHPGGPAILDQVEEKLGLKPEKMSATKHVLSEYGNMSSACVLFILDKMRKKSLEEGHKTTGEGLDWGVLFGFGPGLTVETVVLHSVPV
>Datgl1453S20766
MAAILNYQNRGGRVLGKQLFNPVFQSHSQTPSILRCYCSQRTKNHDEIDEHDHSDKPKSSTKTKRAKAMARIINSQAWSDGIESSLASISPSLSKTTVIETLNYVKDPSKALKFFKWVQETGFTHDGQSYFMMLEILGRSRSLNSARNFLFSIEKGSRGAVKLEARFFNSLIRNYSRAGLFQESIKLFKTMKSLGISPSVISFNSLLSIMLKRGRTNMAKNLYDEMRGTYGVTPDTYTFNTLIRGFCMNGMVDEGFRFFKEMSSFSCDPDVITYNTLVDGLCRGGKVGIAHNVVRGMSKKRADLNPNVVTFTTLIRGFCSKQEIDEALAVFEEMVNKGIKPNKITYNTLIKGLSEVQKFEKIKEILEEAAGNGGFTPDICTFNTLMHAHCNAGNLDEALKVFEKMTELKVQPDSATYSVLIRNLCQRGNYDKAEALFDDLMESEILLKDDGCKPLVAAYNPMFEYLCGNGKTEKAERVFRQLMKKGTQDPPSYKTLIMGHCMEGSYESGFELLVLMLRRDFVPDVEMYESLIDGLLQKGIPLLAQQTLEKMLKSALLPKSSTFHSILANLLEKECPSESANLVQLMLDRKIRQNITFSTHCMKLLFGAGMRERAFQIVGMLYDNGYSVKMDELIGYLCQHKRLLEANNLLLFTLEKHHSVDIEMCNKVIPGLCKINKLSEAFSLYYALVEKGVHQQLACQDILKVSLETGEKRNEAEFVSKRMQQQPELEKSSLQLGSGKSRIKQRGYAEEPVEHSLNKIVPWSDVHPQQELPRKVLYSQLVKLSNGSTLGCNFSFFSNGTSTPYLARSSRVPTQGLATVLAVGKAFPSQLIPQECLVEGYIRDTKCVDVSIKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGSPTIKQRLEIANPAVVEMAKEASLACIKEWGRSVEDITHIVYVTSSEIRLPGGDLYLASELGLRSDVGRIMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTDPIKGLESPFMELNYAVQQFLPNTHHVIDGKLSEEGINFKLGRDLPQKIEDNIEEFCKKLISKANIDDFNTLFWAVHPGGPAILNRLESTLKLKSEKLECSRRALMDYGNVSSNTIFYVMENMREKLKREGGEEWGLALAFGPGITFEGILMRSL
>Datgl2185S24658
MGSEDFAQGVATKKASPGKATILALGKAFPHQLVMQDYLVDGYFKDTNCDDPDLKQKLARLCKTTTVKTRYVVMSEDILKKYPELAIEGQPTVKQRLDICNSAVTKMAIEASQSCIKNWGRPVSDITHLVYVSSSEVRLPGGDLYLATGLGLSPDVQRAMLYFVGCSGGVAGLRLAKDIAENNPGSRVLLATSETTVIGYKPPSANRPYDLVGVALFGDGAGAMIIGADPVSSIERPLFELHTAVQQFLPNTEKIIDGRLTEEGINFKLARELPQIIEDNVEKFCGKLIRTVGIHEKEYNKLFWAVHPGGPAILNRLEKRLDLLPDKLNASRRALMDYGNASSNTIVYVLEYMIEESLKIKKGEDESEEWGLILAFGPGITFEGILARNLAV
>Datgl418S30305
MVTVEEVRKAQRAEGTAMILAIGTANPPNCVQQSAYPDFYFRITNSEHKTDLKKKFKVMCENSKIKKRYMYLTEEILKENPNMCTFDGTSLDARQDMVVVEVPKLGKEAASKALKEWGQPKSNITHLVFCTTSGIDMPGCDYQLTKLLGLRSSVKRLMMYQQGCFGGATGLRLAKDLAENNKGARVLVVCVEINAILFRGPDDSHVDSLIGQVLFGDGASAVIVGAEPIPEVEKPIFQLVSAAQTILPDSEGAIEGHIREVGLTFHLLKEVPKLISTNIEKSLVEAFQPLNISDWNSIFWVVHPGGSSILEKVEEKLALKPEKMRASKHVLSEYGNMSCACVLFILYEMMNNSLKEGHKSTGEGLDWGVLFGFGPGLTVETIVLHSVPI
>Datgl1285S01780
MGSPSVMFILDEMRKKSMEEEKESLGKGLEWGELFGLGPGLADTNRDCKDDSRRTSSSSSVSWKIRAANDANVHDSKKQSKTEDERSVVLLGMVVGESNCIDL
>Datgl1285S19754
MPMENTHYREQAPKGIATILAIGTANPSNFIYQSDYPDFYFRVTKSDHMTELKAKLNRICNKSKINKRHLHMSEDILRDNPNICQYGAPSLDARQNIMVKEVPKLGAEAASQAIKEWGQSISNITHLIFCTSSTISMPSADYQLLKLLGLNPSTKRFMIYQQGCFAGGTALRLAKDLAENNSDARVLIVCSEMTGMIFHGPSETHLDILLGQALFGDGAAAAIVGAYPNSKTERGLYQLMSASQTVVPGTEDAIIGQLREMGLSGYLSSKNPEYVGKNVESCLVEAFNKIGIHDWNSLFYVVHPGGPAILDKVEQNLSLDKEKLSLSRHVLSEYGNMESVSVFFIMDELRKKSMQEGKKNTGQGLEWGVLFGFGPGLTVETVVLRSMTLVD
MVTVEEVRKTQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTDLKEKFKRMCEKSMIRKRYMYLTEEILKENPNICAYDAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQPKSKITHVVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNDSHLDSLVGQALFGDGASAVIVGADPIPEVEKPIFQLVSASQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLNISDWNSIFWIAHPGGPAILDQVEEKLGLKPEKMSATKHVLSEYGNMSSACVLFILDKMRKKSLEEGHKTTGEGLDWGVLFGFGPGLTVETVVLHSVPV
>Datgl1175S19094
MKRSHEDLSLVVLVVVAAAAAVVLMKMLVTSPLLFSSITIVLPPLLAWLHHCLKGSLCFFKPSNKMVTVEEVRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTDLKEKFKHLCERSTIKKRYMYLTEEILKENPNICAFDAPSLDARQDMVVVEVPKLGKEAASKAIEEWGQPKSKITHVVFCTTSGVDTPGCDYQLTRLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSSCLDNLVGQALFSDGASAVIVGADPIPDIEKPIFQLVSAAQTIVPNSEGAVSIHVREVGFTFHLRKDVPEIISKNIEKFLVEAFQPLNISDWNSIFWIAHPGGPAILDHVEEKLKLKPEKMCATKHVLREYGNMSSACVLFILDQMRKKSLEEGHKTTGEGLDWGVLFGFGPGITVETVVLHSMPI
>Datgl1175S19095
MVTVEEVRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTDLKEKFKRMCEKSMIRKRYMYLTEEILKENPNICAYDAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQPKSKITHVVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNDSHLDSLVGQALFGDGASAVIVGADPIPEVEKPIFQLVSASQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLNISDWNSIFWIAHPGGPAILDQVEEKLGLKPEKMSATKHVLGEYGNMSSACVLFILDKMRKKSLEEGHKTTGEGLDWGVLFGFGPGLTVETVVLHSVPI
>Datgl1175S19093
MVTVEEVRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTDLKEKFKRMCDRSMIKKRYMYLTEEILKENPNICAYDAPSLDARQDMVVVEVPKLGKEAASKAIKEWGQPKSKITHVVFCTTSGVDMPGCDYQLTKLLGLRPSVKRLMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPNDSHLDSLVGQALFGDGASAVIVGADPIPEVEKPIFQLVSASQTILPDSEGAIDGHVREVGLTFHLLKDVPGLISKNIEKSLVEAFQPLNISDWNSIFWIAHPGGPAILDQVEEKLGLKPEKMSATKHVLSEYGNMSSACVLFILDKMRKKSLEEGHKTTGEGLDWGVLFGFGPGLTVETVVLHSVPV
>Datgl1453S20766
MAAILNYQNRGGRVLGKQLFNPVFQSHSQTPSILRCYCSQRTKNHDEIDEHDHSDKPKSSTKTKRAKAMARIINSQAWSDGIESSLASISPSLSKTTVIETLNYVKDPSKALKFFKWVQETGFTHDGQSYFMMLEILGRSRSLNSARNFLFSIEKGSRGAVKLEARFFNSLIRNYSRAGLFQESIKLFKTMKSLGISPSVISFNSLLSIMLKRGRTNMAKNLYDEMRGTYGVTPDTYTFNTLIRGFCMNGMVDEGFRFFKEMSSFSCDPDVITYNTLVDGLCRGGKVGIAHNVVRGMSKKRADLNPNVVTFTTLIRGFCSKQEIDEALAVFEEMVNKGIKPNKITYNTLIKGLSEVQKFEKIKEILEEAAGNGGFTPDICTFNTLMHAHCNAGNLDEALKVFEKMTELKVQPDSATYSVLIRNLCQRGNYDKAEALFDDLMESEILLKDDGCKPLVAAYNPMFEYLCGNGKTEKAERVFRQLMKKGTQDPPSYKTLIMGHCMEGSYESGFELLVLMLRRDFVPDVEMYESLIDGLLQKGIPLLAQQTLEKMLKSALLPKSSTFHSILANLLEKECPSESANLVQLMLDRKIRQNITFSTHCMKLLFGAGMRERAFQIVGMLYDNGYSVKMDELIGYLCQHKRLLEANNLLLFTLEKHHSVDIEMCNKVIPGLCKINKLSEAFSLYYALVEKGVHQQLACQDILKVSLETGEKRNEAEFVSKRMQQQPELEKSSLQLGSGKSRIKQRGYAEEPVEHSLNKIVPWSDVHPQQELPRKVLYSQLVKLSNGSTLGCNFSFFSNGTSTPYLARSSRVPTQGLATVLAVGKAFPSQLIPQECLVEGYIRDTKCVDVSIKEKLERLCKTTTVKTRYTVMSKEILDKYPELATEGSPTIKQRLEIANPAVVEMAKEASLACIKEWGRSVEDITHIVYVTSSEIRLPGGDLYLASELGLRSDVGRIMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTDPIKGLESPFMELNYAVQQFLPNTHHVIDGKLSEEGINFKLGRDLPQKIEDNIEEFCKKLISKANIDDFNTLFWAVHPGGPAILNRLESTLKLKSEKLECSRRALMDYGNVSSNTIFYVMENMREKLKREGGEEWGLALAFGPGITFEGILMRSL
>Datgl2185S24658
MGSEDFAQGVATKKASPGKATILALGKAFPHQLVMQDYLVDGYFKDTNCDDPDLKQKLARLCKTTTVKTRYVVMSEDILKKYPELAIEGQPTVKQRLDICNSAVTKMAIEASQSCIKNWGRPVSDITHLVYVSSSEVRLPGGDLYLATGLGLSPDVQRAMLYFVGCSGGVAGLRLAKDIAENNPGSRVLLATSETTVIGYKPPSANRPYDLVGVALFGDGAGAMIIGADPVSSIERPLFELHTAVQQFLPNTEKIIDGRLTEEGINFKLARELPQIIEDNVEKFCGKLIRTVGIHEKEYNKLFWAVHPGGPAILNRLEKRLDLLPDKLNASRRALMDYGNASSNTIVYVLEYMIEESLKIKKGEDESEEWGLILAFGPGITFEGILARNLAV
>Datgl418S30305
MVTVEEVRKAQRAEGTAMILAIGTANPPNCVQQSAYPDFYFRITNSEHKTDLKKKFKVMCENSKIKKRYMYLTEEILKENPNMCTFDGTSLDARQDMVVVEVPKLGKEAASKALKEWGQPKSNITHLVFCTTSGIDMPGCDYQLTKLLGLRSSVKRLMMYQQGCFGGATGLRLAKDLAENNKGARVLVVCVEINAILFRGPDDSHVDSLIGQVLFGDGASAVIVGAEPIPEVEKPIFQLVSAAQTILPDSEGAIEGHIREVGLTFHLLKEVPKLISTNIEKSLVEAFQPLNISDWNSIFWVVHPGGSSILEKVEEKLALKPEKMRASKHVLSEYGNMSCACVLFILYEMMNNSLKEGHKSTGEGLDWGVLFGFGPGLTVETIVLHSVPI
>Datgl1285S01780
MGSPSVMFILDEMRKKSMEEEKESLGKGLEWGELFGLGPGLADTNRDCKDDSRRTSSSSSVSWKIRAANDANVHDSKKQSKTEDERSVVLLGMVVGESNCIDL
>Datgl1285S19754
MPMENTHYREQAPKGIATILAIGTANPSNFIYQSDYPDFYFRVTKSDHMTELKAKLNRICNKSKINKRHLHMSEDILRDNPNICQYGAPSLDARQNIMVKEVPKLGAEAASQAIKEWGQSISNITHLIFCTSSTISMPSADYQLLKLLGLNPSTKRFMIYQQGCFAGGTALRLAKDLAENNSDARVLIVCSEMTGMIFHGPSETHLDILLGQALFGDGAAAAIVGAYPNSKTERGLYQLMSASQTVVPGTEDAIIGQLREMGLSGYLSSKNPEYVGKNVESCLVEAFNKIGIHDWNSLFYVVHPGGPAILDKVEQNLSLDKEKLSLSRHVLSEYGNMESVSVFFIMDELRKKSMQEGKKNTGQGLEWGVLFGFGPGLTVETVVLRSMTLVD
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University