Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Datisca glomerata
Species name
Datisca glomerata is a species of eudicot in the family Datiscaceae.
Species info
Gene sequence info
Datisca_glomerata.4CL.fa
Download
>Datgl1359S20303
MATETNHNNFIFRSKLPDIPIPNHLPLHTYCFHNKSNISSRPCLINGTTGHVYTYAEVELTTRRVASGLNKLGIRQGDVIMLLLPNSPEFVLSFLGASCRGAIMTAANPFFTPAEIAKQAKASKAKLIITQASYYEKVKDLAGSENDSVKVMCVDLAPNENCLHFSSLTEANEEELPEMEIKPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYYHSKDVILCALPLFHIYSLNSVLLCGLRAGAALLIMPKFDIVTLLRLIEKYKVSIAPIVPPIVLAISNSPDLDNYDLSSVRLIKSGGAPLGKELEDTVRAKFPRAVLGQGYGMTEAGPVLTMSLAFAKEPFEVKAGACGTVVRNAELKIVDTETGESLPRNQPGEICIRGDQIMKGYVNDAESTAGTIDKEGWLHTGDIGFIDDDDELYIVDRLKELIKYKGFQVAPAELEALLLTHPSVSDAAVVPMKDEQAGEVPVAFVVISESSSITEDEIKQFISKQVVFYKRLSRVFFTNAIPKSPSGKILRKELRAKLATDFPN
>Datgl56S32426
MPMLITEGVLLAGNAIIMNQQILTNKTPSQSHPHLSTHQLISCTKHETTLHHPPSPLKRESSEPTSLHPVHLCTMETKNEEHIFCSQYQAVHVPDNVTLPEFVLQHAELYANKVAFVEAVSGKEVTYGEVVRDTKRLSKALRSLGLRKGHVVIVVLPNVVEYAIVALGVMSAGGVFSGANPSAHVSEIKKQAEVADAKLIVTNIPNYEKVKGLEIPVVVLGEELIEGTMNWNKLLEAADRAGTNSTDEDVQQSDLCALPFSSGTTGISKGVMLTHRNMVANLCSTLAGVPSEMVGQVTTLGLIPFFHIYGITGICCATLRNKGKVVVMARFELRTFLNALITQEVTFAPIVPPIILALVKNPIVEEFDLSRLKLQAVMTAAAPLAPELLSTFENKFPGVHVQEAYGLTEHSCITLTYGNINKGDGKAKRNTVGKILPNLQVKFIDPDTGRSLPKNTPGEICVKSQCVMLGYYKNVEETSRTIDINGWLHTGDIGYIDDDGDIFIVDRIKEMIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAASIVMAQNAKESEEEIIKYVASNVASYKKVRVVHFVDNIPKSPSGKIMRRLIKDNMIQTIRANTII
>Datgl267S25924
MEKSGYGRDGIFRSLRPPLVLPKDPNLSMVSFLFRNSFSYPHKPALIDAESSETLTFSQLQSVVIKVSHGLLHLGIKKNDVVLIFAPNSIQFAICFLGVVAIGAIATTCNPIYTVSELTNQVKDSKPKFVITVHEMWDKLKDFNLPAVFLGPQGSSAISSSSNIVSFHDLVDLGASESDFPVVGVKQSDTATLLYSSGTTGTSKGVILTHRNFISASIMATMDQVLAGEMHNVFLNVLPMFHVFGLACILLSQLQKGNVIVLMAKFDFERILWAVEKYKVTDLWIVPPIVLALAKQSLVKKYNLSSLKHIGSGAAPLGKELMEECCRNIPSAVVIQGYGMTETCGVVSMENTNVGIRNTGSAGTLASGIESHIVSVDTLKPLPPNQLGEIWVRGPSIMKGYFNNPQATKQTIDKNGWLHTGDLGYFDENGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEEDILKFIANQVRNYVPGCSFIVKPDNWIEGDVKCNSISRDCNQVNSSIAWAKALYSLYVLDLATTCFSLEDHDTKLGPRNTTYPHVDLLPSGQLAQSASVNDVAPYKRLRRVAFINSVPKSASGKILRRELIEKVRSKI
>Datgl7S35052
MDPQLNQHDFIFRSKLPDIYIPDHLPLHSYCFENISQFKDRPCLINGPTGETYTYAEVELTARKVAAGLHKIGIKQGDVIMLLLQNGPQFVFAFLGASYLGAMSTTANPFYTPAEVTKQAKAANAKLIITQTPFVEKVKDFAEENHVQVMCIDSTTPPPERCLHFSELTQADETDIPAVKINADDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFKKEDVIACVLPLFHIYSLNSVLLCGLRVGAAILIMQKYEIRALLELVQKYKVTVAPFVPPIVLDIAKNTDINKYDLSSIRMVMSGAAPMGRELEDTVRAKLPNATLGQGYGMTEAGPVLSMCLAFAKEPFKIKSGACGTVVRNAEMKIIDPDTGSSLPRNQAGEICIRGNQIMKGYLNNQEATEQTIDKDGWLHTGDIGYIDEDDELFIVDRLKELIKYKGYQVAPAELEAMLTDHSQISAAAVVPMKDEAAGEVPVAFIVRSNGSKISEDEIKKYISDKVVFYKRIKRVIFVESIPVAPSGKILRKDLRARIAEGIPN
>Datgl480S31144
MAIQTNQNDIVFRSKLPDIYIPKHLPLHFYCFENIAKIGPRPCLINSTTGDIHTYADVELNARKVASGLSRLDIGQGDVIMLLLPNTPEFVLAFLGTSHLGAIMTAANPFFTPAEIAKQAKASKAKLIITQACYYDKVKDLKNETGAKIMCIDSPPQGCLSFLELTQANEEDLPKVEINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYYHNEDVILCVLPLFHIYSLNSVLLCGLRAGATILMMQKFDINSLLQLIQKYKVSIAPVVPPIVLAIAKSPDLDKYDLSSIRVLKSGGAPLGKELEDTVRAKFPMAVLGQGYGMTEAGPVLTMSLAFAKEPLGVKAGACGSVVRNAEMKIVDTETGASLPRNIPGEICIKGDQIMKGYLNDPEATERTIDKKGYLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPDISDAAVVPMNDEQAGEVPVAFVVTENKSNITEDELKQYISKQVVFYKRLSRVFLIDAIPKSPSGKILRKNLKAKLATGFPN
>Datgl208S24300
MGKSFNPQTQTYLSPRPPLHFPTNPNLSITTFLFQNSSSFPHRLALIDADTGETLTFYQLKIQVSKLAHALLKLNIAKNDVVLIFAPNSIHFPVCFLAILALGAIATTCNPSYTAAELSKQLKDCKPKFIITVPELFEKIGELNVPTILLGPPSLRNFAANSNQSVWHYSELIERSGGVVDIPVSYVAQNDAAALLYSSGTIGTSKGVILTHENFIASSLMLTEDQDHYGDPSNVFLCFLPMYHVFGLAVIVYAQLRRGNTVVSMGKFEFEKALGAVEKYRVTHLYVVPPVMIALAKQSVVKKYDLSSLRQLLSGAAPLGKDVMEECAKNIPNANIIQGYGMTETCGIISVENAMEGSRFSGASGTLVSGVEAKIVSVDTLKSLPPHQLGEIYVRGPNMMKGYLNNIEATSLTIDDQGWVHTGDLGYFNDEGELFVVDRIKELIKSYGFQVAPAELEGLLLSHPEITDAVVIPYPDEKAGEVPIAFVVRSSSSSITEDDVQKFIANQVAPFKRLRRVTFVNSVPKSASGKILRRELRDRIRAKI
>Datgl1020S17638
MITVASSLENQQSEISQNHFQSDSKQIHIFKSRLPDIPISNHLPLPTYCFEHLLETSDRPCLIVGSTGKVYTYADTHLICKRIGVGISKLGINKGDVVMVLLQNCAEFVFSFLGAAMIGAITTTANPYYTASEIFKQLKLSGAKMIITQSQYVDKLRDSAENDPKLGEDFTVITVDDAPEQCLHFSVISEANENDFPNVEINPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNMYVKQEDVALCVLPLFHIYSMSSVLLCSLRGGAAVLLMQKFEMGAFLELIQKHRVSLAAVVPPLVLTLAKNPIVAEFDLSSIRLVLSGAAPLGKELEDALRSRLPQAVLGQGYGMTEAGPVLSMCPAFAKQPIPSKSGSCGIVVRNAELKVVDPETGCSLGYNQPGEICIRGAQIMKGYLNDPEATANTIDVDGWLHTGDIGYVDDDDEVFIVDRVPPAELESLLVNHPLIADAAVVPQKDDVAGEVPVAFVVRSNGSELTEESIKEYIAKQVVFYKKLQKVYFVHAIPKSPSGKILRKELRAKLAAASPLP
MATETNHNNFIFRSKLPDIPIPNHLPLHTYCFHNKSNISSRPCLINGTTGHVYTYAEVELTTRRVASGLNKLGIRQGDVIMLLLPNSPEFVLSFLGASCRGAIMTAANPFFTPAEIAKQAKASKAKLIITQASYYEKVKDLAGSENDSVKVMCVDLAPNENCLHFSSLTEANEEELPEMEIKPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYYHSKDVILCALPLFHIYSLNSVLLCGLRAGAALLIMPKFDIVTLLRLIEKYKVSIAPIVPPIVLAISNSPDLDNYDLSSVRLIKSGGAPLGKELEDTVRAKFPRAVLGQGYGMTEAGPVLTMSLAFAKEPFEVKAGACGTVVRNAELKIVDTETGESLPRNQPGEICIRGDQIMKGYVNDAESTAGTIDKEGWLHTGDIGFIDDDDELYIVDRLKELIKYKGFQVAPAELEALLLTHPSVSDAAVVPMKDEQAGEVPVAFVVISESSSITEDEIKQFISKQVVFYKRLSRVFFTNAIPKSPSGKILRKELRAKLATDFPN
>Datgl56S32426
MPMLITEGVLLAGNAIIMNQQILTNKTPSQSHPHLSTHQLISCTKHETTLHHPPSPLKRESSEPTSLHPVHLCTMETKNEEHIFCSQYQAVHVPDNVTLPEFVLQHAELYANKVAFVEAVSGKEVTYGEVVRDTKRLSKALRSLGLRKGHVVIVVLPNVVEYAIVALGVMSAGGVFSGANPSAHVSEIKKQAEVADAKLIVTNIPNYEKVKGLEIPVVVLGEELIEGTMNWNKLLEAADRAGTNSTDEDVQQSDLCALPFSSGTTGISKGVMLTHRNMVANLCSTLAGVPSEMVGQVTTLGLIPFFHIYGITGICCATLRNKGKVVVMARFELRTFLNALITQEVTFAPIVPPIILALVKNPIVEEFDLSRLKLQAVMTAAAPLAPELLSTFENKFPGVHVQEAYGLTEHSCITLTYGNINKGDGKAKRNTVGKILPNLQVKFIDPDTGRSLPKNTPGEICVKSQCVMLGYYKNVEETSRTIDINGWLHTGDIGYIDDDGDIFIVDRIKEMIKYKGFQVAPAELEAILLTHPSVEDVAVVPLPDEEAGEIPAASIVMAQNAKESEEEIIKYVASNVASYKKVRVVHFVDNIPKSPSGKIMRRLIKDNMIQTIRANTII
>Datgl267S25924
MEKSGYGRDGIFRSLRPPLVLPKDPNLSMVSFLFRNSFSYPHKPALIDAESSETLTFSQLQSVVIKVSHGLLHLGIKKNDVVLIFAPNSIQFAICFLGVVAIGAIATTCNPIYTVSELTNQVKDSKPKFVITVHEMWDKLKDFNLPAVFLGPQGSSAISSSSNIVSFHDLVDLGASESDFPVVGVKQSDTATLLYSSGTTGTSKGVILTHRNFISASIMATMDQVLAGEMHNVFLNVLPMFHVFGLACILLSQLQKGNVIVLMAKFDFERILWAVEKYKVTDLWIVPPIVLALAKQSLVKKYNLSSLKHIGSGAAPLGKELMEECCRNIPSAVVIQGYGMTETCGVVSMENTNVGIRNTGSAGTLASGIESHIVSVDTLKPLPPNQLGEIWVRGPSIMKGYFNNPQATKQTIDKNGWLHTGDLGYFDENGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDAEAGEVPVAYVVRSPNSSLTEEDILKFIANQVRNYVPGCSFIVKPDNWIEGDVKCNSISRDCNQVNSSIAWAKALYSLYVLDLATTCFSLEDHDTKLGPRNTTYPHVDLLPSGQLAQSASVNDVAPYKRLRRVAFINSVPKSASGKILRRELIEKVRSKI
>Datgl7S35052
MDPQLNQHDFIFRSKLPDIYIPDHLPLHSYCFENISQFKDRPCLINGPTGETYTYAEVELTARKVAAGLHKIGIKQGDVIMLLLQNGPQFVFAFLGASYLGAMSTTANPFYTPAEVTKQAKAANAKLIITQTPFVEKVKDFAEENHVQVMCIDSTTPPPERCLHFSELTQADETDIPAVKINADDVVALPYSSGTTGLPKGVMLTHRGLVTSVAQQVDGENPNLYFKKEDVIACVLPLFHIYSLNSVLLCGLRVGAAILIMQKYEIRALLELVQKYKVTVAPFVPPIVLDIAKNTDINKYDLSSIRMVMSGAAPMGRELEDTVRAKLPNATLGQGYGMTEAGPVLSMCLAFAKEPFKIKSGACGTVVRNAEMKIIDPDTGSSLPRNQAGEICIRGNQIMKGYLNNQEATEQTIDKDGWLHTGDIGYIDEDDELFIVDRLKELIKYKGYQVAPAELEAMLTDHSQISAAAVVPMKDEAAGEVPVAFIVRSNGSKISEDEIKKYISDKVVFYKRIKRVIFVESIPVAPSGKILRKDLRARIAEGIPN
>Datgl480S31144
MAIQTNQNDIVFRSKLPDIYIPKHLPLHFYCFENIAKIGPRPCLINSTTGDIHTYADVELNARKVASGLSRLDIGQGDVIMLLLPNTPEFVLAFLGTSHLGAIMTAANPFFTPAEIAKQAKASKAKLIITQACYYDKVKDLKNETGAKIMCIDSPPQGCLSFLELTQANEEDLPKVEINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGDNPNLYYHNEDVILCVLPLFHIYSLNSVLLCGLRAGATILMMQKFDINSLLQLIQKYKVSIAPVVPPIVLAIAKSPDLDKYDLSSIRVLKSGGAPLGKELEDTVRAKFPMAVLGQGYGMTEAGPVLTMSLAFAKEPLGVKAGACGSVVRNAEMKIVDTETGASLPRNIPGEICIKGDQIMKGYLNDPEATERTIDKKGYLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPDISDAAVVPMNDEQAGEVPVAFVVTENKSNITEDELKQYISKQVVFYKRLSRVFLIDAIPKSPSGKILRKNLKAKLATGFPN
>Datgl208S24300
MGKSFNPQTQTYLSPRPPLHFPTNPNLSITTFLFQNSSSFPHRLALIDADTGETLTFYQLKIQVSKLAHALLKLNIAKNDVVLIFAPNSIHFPVCFLAILALGAIATTCNPSYTAAELSKQLKDCKPKFIITVPELFEKIGELNVPTILLGPPSLRNFAANSNQSVWHYSELIERSGGVVDIPVSYVAQNDAAALLYSSGTIGTSKGVILTHENFIASSLMLTEDQDHYGDPSNVFLCFLPMYHVFGLAVIVYAQLRRGNTVVSMGKFEFEKALGAVEKYRVTHLYVVPPVMIALAKQSVVKKYDLSSLRQLLSGAAPLGKDVMEECAKNIPNANIIQGYGMTETCGIISVENAMEGSRFSGASGTLVSGVEAKIVSVDTLKSLPPHQLGEIYVRGPNMMKGYLNNIEATSLTIDDQGWVHTGDLGYFNDEGELFVVDRIKELIKSYGFQVAPAELEGLLLSHPEITDAVVIPYPDEKAGEVPIAFVVRSSSSSITEDDVQKFIANQVAPFKRLRRVTFVNSVPKSASGKILRRELRDRIRAKI
>Datgl1020S17638
MITVASSLENQQSEISQNHFQSDSKQIHIFKSRLPDIPISNHLPLPTYCFEHLLETSDRPCLIVGSTGKVYTYADTHLICKRIGVGISKLGINKGDVVMVLLQNCAEFVFSFLGAAMIGAITTTANPYYTASEIFKQLKLSGAKMIITQSQYVDKLRDSAENDPKLGEDFTVITVDDAPEQCLHFSVISEANENDFPNVEINPDDPVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNMYVKQEDVALCVLPLFHIYSMSSVLLCSLRGGAAVLLMQKFEMGAFLELIQKHRVSLAAVVPPLVLTLAKNPIVAEFDLSSIRLVLSGAAPLGKELEDALRSRLPQAVLGQGYGMTEAGPVLSMCPAFAKQPIPSKSGSCGIVVRNAELKVVDPETGCSLGYNQPGEICIRGAQIMKGYLNDPEATANTIDVDGWLHTGDIGYVDDDDEVFIVDRVPPAELESLLVNHPLIADAAVVPQKDDVAGEVPVAFVVRSNGSELTEESIKEYIAKQVVFYKKLQKVYFVHAIPKSPSGKILRKELRAKLAAASPLP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University