Enzyme
The enzyme participates in the flavonoid biosynthesis pathway found in plants. It catalyses the double reduction of anthocyanidins, producing (2R,3R)-flavan-3-ol monomers required for the formation of proanthocyanidins. While the enzyme from the legume Medicago truncatula (MtANR) can use both NADPH and NADH as reductant, that from the crucifer Arabidopsis thaliana (AtANR) uses only NADPH. Also, while the substrate preference of MtANR is cyanidin>pelargonidin>delphinidin, the reverse preference is found with AtANR. cf. EC 1.3.1.112, anthocyanidin reductase [(2S)-flavan-3-ol-forming].
ANR
Enzyme
Anthocyanidin reductase
Enzyme name
EC:1.3.1.77
Entry
Oxidoreductases;Acting on the CH-CH group of donors;With NAD+ or NADP+ as acceptor
Class
(2R,3R)-flavan-3-ol:NAD(P)+ 3,4-oxidoreductase
Sysname
a (2R,3R)-flavan-3-ol + 2 NAD(P)+ = an anthocyanidin with a 3-hydroxy group + 2 NAD(P)H + H+ [RN:R07351 R07352]
Reaction
anthocyanidin with a 3-hydroxy group [CPD:C21381];NADH [CPD:C00004];NADPH [CPD:C00005];H+ [CPD:C00080]
Product
Species information
Daemonorops jenkinsiana
Species name
Species info
Gene sequence info
Daemonorops_jenkinsiana.ANR.fa
Download
>DJ01Gene71256
MLSPEKERFRTKNWETNGEEQVCVTGASSFLASWLVKELLKKGHVVHATLRNLEDKSKTQLLKSFPGADTRLHLFEAELYNPLTFEAAIQGTEFVFLLATPMQHNANSSQYKDTTQAAVAAVRSILQLCERSGTVKRVINTGSVTAASPFKEDGTSFKDFIDESCWTPLHRTFAYCEDFEKSYICSKTESEKEVLSYNYKEGKKEFEVVSLACAVVGGDSLLPAVPLSVQCMVSPLTGDKVNHRQMKFLQALLGSVPLVHIKDVCEAHIFCMEKPSMAGRFLLASAYPTMQEIVDYYTQNYPELRVIKEVEGDGHGIGCRSKKLADMGFKFRYDMKQILNDSVETAKRLGCLDELA
>DJ01Gene16078
MTEGKPACVTGGTGFMASALIKQLLEKGYAVNATVRDPDKNELIKPAVQGILNVMKSCLKANSVKRFVLTSSAAAVSIKQPTKNNLMLDEESWSDMEFLTDNKLPTCAYGVSKMLTERREALRFAQENNITLVTMIPALTIGPALASIQFCRKHRHRHGPVLANSFGELPERAKLSLSSEKLIKAGFKFKYRQLEEIYDETIKYALATGLLAPK
>DJ01Gene19758
MDGSDPSSSSSAAAAAKTTVCVTGATGYIGSWLVRSLLQRGYSVHATARDPGKAWCLLSTFSGNSQLKIFRADLNEEGSFDEAVKGCFGVFHVAASMEFDIPVEENIEDYARSKIIEPAVRGTLNVLQACSRAGSVKRIIFTSSVSTITAKDDKGEWRSLVDESSVTPVNVVWNTKPKGWVYVLSKLLTEEKAFQIAKEKGMDLVSIIPPTVAGPFLTTSVPASIRVLLSPVTGDPNFYPILVSVHSRLGSIPLVHIEDICSAHIFLMEQAAAEVPKGLTRDSIMQSLQ
>DJ01Gene25449
MSGSGKVVCVTGASGYIASWLVKLLLKRGYTVRASVRDLADPKKTEHLRALEGAGERLHLLKANLLEEGSFDSVVQGCEGVFHTASPFYHNVTDPQVELIDPAVKGTLNVSVPALKLLLLKGAEVCKEAKMWYVLSKTLAEEAAWKFSKDNSIDMVTINPAMVIGPLLQPTLNTSAATILNMINGSSTYTNATFGWVHVRDVAMAHILALEVPSASGRYCLVERVAHCSEIVKILHEQYPALQLPEKCADDKPFVPIYQVSKERTKSLGIDYIPLEASIKETVESLKEKGFAVF
>DJ01Gene37575
MERRSKVCVTGASGFLASWLVKELLKKGHVVHATLRNLEDKSKTQLLKSFPGADTRLHLFEAELYNPLTFEAAIQGTEFVFLLATPMQHNANSSQYKDTTQAAVAAVRSILQLCERSGTVKRVINTGSVTAASPFKEDGTSFKDFIDESCWTPLHRTFAYCEDFEKSYICSKTESEKEVLSYNYKEGKKEFEVVSLACAVVGGDSLLPAVPLSVQCMVSPLTGDKVNHRQMKFLQALLGSVPLVHIKDVCEAHIFCMEKPSMAGRFLLASAYPTMQEIVDYYTQNYPELRVIKEVEGDGHGIGCRSKKLADMGFKFRYDMKQILNDSVETAKRLGCLDELA
>DJ01Gene33728
MEAAGEKGRVCVTGAGGYLASWLVKLLLSNGYKVHGTVRDLSVKKNSHLRKFEKASENLQLFKADLLDYGTLKAAIAGCEGVFHVASPVPASKILDPELELITPAVNGTLNVLQACSEMKIKRVVVVSSTAAVELNPHGHMISSRMRSVGQMKNFASRPRTGIASQRLWQSMQLGRGPEPVKDNFWNIVDVRDVADALLLVYEKPESSGRYICAAYQNSIQNLIDLLKEMYPNYGYQKNLTEVPRNTPVTSEKLKKLGWKCRPVEETLVDSVECYREAGLLDEQDGHAYLPPFFN
>DJ01Gene42393
MPVYCVTGGTGLLAAHLVRSLLAEGNTVRATVRDPGDEAKVGFLWNLDGAKERLRLVKADLMVEGSFDEAVDGADGVFHMASPVFVPPDQNPQETLIDPAIRGTANVLRSCSKASSVRRVVLTSSSTAVRYRQDATLVLPLNESHWSDLEYCKRYDELLISLPSPNRTLIWIEWQLWYPYAKVLAEKRHGD
>DJ01Gene42415
MPEYCVTGGTSLLAAHLIRSLLAEGHTVRVTVRDPGRDEAKVGFLWNLDGAKGRLRLVKVDLMVEGSFDEAVDGADGVFHVASPVFVPSDQNPWETLIDLAIRGTANYCCQVSTRCNLVSPLNESHWSDLEYCKRYDLWYPYAKVLAEQEAWRLAKEYGIDLVVVLPSFVVGPLFTPQPRSTLQMILSIIKAHWSEIVEMLRAKYPTYPIPNKCGNEKGVSIPHSMDTTKIRELGLPPFRQFPRCLMTASRVSKREDFCENLESHHKNDPALENSNIC
>DJ01Gene43090
MSLVNKHYFFRFADPQARDLALARPWVVNGQALAVSAWQAEFVLGSDSVLSALLWIRLPLLPMEFWTEEILASILSVAGVYQYSDAATKSKNRGGFARACVRVDLGRSLRPGVRVRGTKQPFWQQFSYENLEGICGSCGALHHAEPCSMQPELHSSTDGVRFGPWMAAVRRRKTPVLLTPAIGKKDQGPVLHSPVSMEGWQVPKNPVRRKGNRGSIADQSPSFSPKASGSSRRATVQPCRSKSSVPVPASESHFGELMTDSQQPLPRGNNPFSALVSELETMSPEPSKDLTPCQSKRARPIDSNPQRRASKASKAKGKGSLSAKGKEPASFTFSASADSVQGSCLHTQRGTKKLRNMAEPTLESASGVPQLVQRGDNTHEAVVYQLKQAILKDNIVVDVDSSQSEMARGNGLIEDFPPACDHSNELIKPAVQGILNVMKSCLKANSVKRFVLTSSAAAVSIKQPTKNNLMLDEESWSDMEFLTDNKLPTCAYGVSKMLTERREALRFAQENNITLVTMIPALTIGPALASSQFCRKHRHRHGPVLANSFGELPERAKLSLSSEKLIKAGFKFKYRQLEEIYDETIKYALATGLLAPK
>DJ01Gene47735
MERRSKVCVTGASGYLGSWLVKKLLKNGHVVHATLRNLEDKSKTQLLKSFPGANTRMHLFEAELYNPLTFEAAIQGCEFVFLLATPLQHNANSQYKDTTQAAVAAVRSILQLCERSGTVKRVIYTGSVTAASPLKEDGMGFKDFIDESHWTPLHLAFAYCEDFEKSYICSKTESEKEVLSYNYKEGIKKEFEVVSLVCALVGGDTVLSIVPLSVRCTISPLTGDKVNHRQMKFLQALLGSVPLVHIKDVCEAHIFCMEKPSMAGRFLLASAYPTMQEIVDHYTQNYPKLRAIKEVEGDGHGIGCRSTKLADMGFKFRYDVKQILDASVETAKRLGCLDELA
>DJ01Gene51260
MTSEGKLACVTGATGFIASALIKQLLEKGYAVNATVRYPENWEKLSPLREMQNLGSLKIFRADLRDEGSFDEAVAGSDYVFYVAAPLNLHTDDPERDYGGFRIARGRRGFRGPRPRRLRXTGATGFIASALIKQLLEKGYAVNATVRYPEIWEKLSPLREMQNLGSLKIFRADLRDEGSFDEAVAGSDYVFYVAAPLNLHTDDPESCRGLKETSNFAEAETEAEVARTMVEAAEAKVEAAEAETKAEVAGTVAEAAEAKAEAETEAEVARTMAEATEAVAEAEAEAAEVTEMAEAVKAETEAEVAGTVVEAVEVKVKAACRGCSDMLSLC
>DJ01Gene51258
MTNEGKLACVTGATGFIASALIKQLLEKGYAVNATVRDPENWEKLSPLREMQNLGSLKIFRADLRDEGSFDEAVAGSDYVFYVAAPVNLHTDDPENELIKPAVQGVLNVMKSCLKAKSVKRFVLTSSAAAVSIKRPAKSSLTLDEESWSDMEFLTIDKPPTWGYGVSKMLTEREALKFAQENNISLVTIIPSLTIGPAPTATFKRGRHSHGPELANR
>DJ01Gene65722
MAAENSEKLSQLKEMHNLGSLKIFQANLRDEGSFDAAVAGCDYVFYVAAPVILNANDPENELIKPAVQGILNVMKSCLKANSVKRFVLTSSAAAVSIKQPTKNNLMLDEESWSDMEFLTDNKLPTCAYGVSKMLTERREALRFAQENNITLVTMIPALTIGPALASSQFCRKHRHRHGPVLANSFGELPERAKLSLSSEKLIKAGFKFKYRQLEEIYDETIKYALATGLLAPK
MLSPEKERFRTKNWETNGEEQVCVTGASSFLASWLVKELLKKGHVVHATLRNLEDKSKTQLLKSFPGADTRLHLFEAELYNPLTFEAAIQGTEFVFLLATPMQHNANSSQYKDTTQAAVAAVRSILQLCERSGTVKRVINTGSVTAASPFKEDGTSFKDFIDESCWTPLHRTFAYCEDFEKSYICSKTESEKEVLSYNYKEGKKEFEVVSLACAVVGGDSLLPAVPLSVQCMVSPLTGDKVNHRQMKFLQALLGSVPLVHIKDVCEAHIFCMEKPSMAGRFLLASAYPTMQEIVDYYTQNYPELRVIKEVEGDGHGIGCRSKKLADMGFKFRYDMKQILNDSVETAKRLGCLDELA
>DJ01Gene16078
MTEGKPACVTGGTGFMASALIKQLLEKGYAVNATVRDPDKNELIKPAVQGILNVMKSCLKANSVKRFVLTSSAAAVSIKQPTKNNLMLDEESWSDMEFLTDNKLPTCAYGVSKMLTERREALRFAQENNITLVTMIPALTIGPALASIQFCRKHRHRHGPVLANSFGELPERAKLSLSSEKLIKAGFKFKYRQLEEIYDETIKYALATGLLAPK
>DJ01Gene19758
MDGSDPSSSSSAAAAAKTTVCVTGATGYIGSWLVRSLLQRGYSVHATARDPGKAWCLLSTFSGNSQLKIFRADLNEEGSFDEAVKGCFGVFHVAASMEFDIPVEENIEDYARSKIIEPAVRGTLNVLQACSRAGSVKRIIFTSSVSTITAKDDKGEWRSLVDESSVTPVNVVWNTKPKGWVYVLSKLLTEEKAFQIAKEKGMDLVSIIPPTVAGPFLTTSVPASIRVLLSPVTGDPNFYPILVSVHSRLGSIPLVHIEDICSAHIFLMEQAAAEVPKGLTRDSIMQSLQ
>DJ01Gene25449
MSGSGKVVCVTGASGYIASWLVKLLLKRGYTVRASVRDLADPKKTEHLRALEGAGERLHLLKANLLEEGSFDSVVQGCEGVFHTASPFYHNVTDPQVELIDPAVKGTLNVSVPALKLLLLKGAEVCKEAKMWYVLSKTLAEEAAWKFSKDNSIDMVTINPAMVIGPLLQPTLNTSAATILNMINGSSTYTNATFGWVHVRDVAMAHILALEVPSASGRYCLVERVAHCSEIVKILHEQYPALQLPEKCADDKPFVPIYQVSKERTKSLGIDYIPLEASIKETVESLKEKGFAVF
>DJ01Gene37575
MERRSKVCVTGASGFLASWLVKELLKKGHVVHATLRNLEDKSKTQLLKSFPGADTRLHLFEAELYNPLTFEAAIQGTEFVFLLATPMQHNANSSQYKDTTQAAVAAVRSILQLCERSGTVKRVINTGSVTAASPFKEDGTSFKDFIDESCWTPLHRTFAYCEDFEKSYICSKTESEKEVLSYNYKEGKKEFEVVSLACAVVGGDSLLPAVPLSVQCMVSPLTGDKVNHRQMKFLQALLGSVPLVHIKDVCEAHIFCMEKPSMAGRFLLASAYPTMQEIVDYYTQNYPELRVIKEVEGDGHGIGCRSKKLADMGFKFRYDMKQILNDSVETAKRLGCLDELA
>DJ01Gene33728
MEAAGEKGRVCVTGAGGYLASWLVKLLLSNGYKVHGTVRDLSVKKNSHLRKFEKASENLQLFKADLLDYGTLKAAIAGCEGVFHVASPVPASKILDPELELITPAVNGTLNVLQACSEMKIKRVVVVSSTAAVELNPHGHMISSRMRSVGQMKNFASRPRTGIASQRLWQSMQLGRGPEPVKDNFWNIVDVRDVADALLLVYEKPESSGRYICAAYQNSIQNLIDLLKEMYPNYGYQKNLTEVPRNTPVTSEKLKKLGWKCRPVEETLVDSVECYREAGLLDEQDGHAYLPPFFN
>DJ01Gene42393
MPVYCVTGGTGLLAAHLVRSLLAEGNTVRATVRDPGDEAKVGFLWNLDGAKERLRLVKADLMVEGSFDEAVDGADGVFHMASPVFVPPDQNPQETLIDPAIRGTANVLRSCSKASSVRRVVLTSSSTAVRYRQDATLVLPLNESHWSDLEYCKRYDELLISLPSPNRTLIWIEWQLWYPYAKVLAEKRHGD
>DJ01Gene42415
MPEYCVTGGTSLLAAHLIRSLLAEGHTVRVTVRDPGRDEAKVGFLWNLDGAKGRLRLVKVDLMVEGSFDEAVDGADGVFHVASPVFVPSDQNPWETLIDLAIRGTANYCCQVSTRCNLVSPLNESHWSDLEYCKRYDLWYPYAKVLAEQEAWRLAKEYGIDLVVVLPSFVVGPLFTPQPRSTLQMILSIIKAHWSEIVEMLRAKYPTYPIPNKCGNEKGVSIPHSMDTTKIRELGLPPFRQFPRCLMTASRVSKREDFCENLESHHKNDPALENSNIC
>DJ01Gene43090
MSLVNKHYFFRFADPQARDLALARPWVVNGQALAVSAWQAEFVLGSDSVLSALLWIRLPLLPMEFWTEEILASILSVAGVYQYSDAATKSKNRGGFARACVRVDLGRSLRPGVRVRGTKQPFWQQFSYENLEGICGSCGALHHAEPCSMQPELHSSTDGVRFGPWMAAVRRRKTPVLLTPAIGKKDQGPVLHSPVSMEGWQVPKNPVRRKGNRGSIADQSPSFSPKASGSSRRATVQPCRSKSSVPVPASESHFGELMTDSQQPLPRGNNPFSALVSELETMSPEPSKDLTPCQSKRARPIDSNPQRRASKASKAKGKGSLSAKGKEPASFTFSASADSVQGSCLHTQRGTKKLRNMAEPTLESASGVPQLVQRGDNTHEAVVYQLKQAILKDNIVVDVDSSQSEMARGNGLIEDFPPACDHSNELIKPAVQGILNVMKSCLKANSVKRFVLTSSAAAVSIKQPTKNNLMLDEESWSDMEFLTDNKLPTCAYGVSKMLTERREALRFAQENNITLVTMIPALTIGPALASSQFCRKHRHRHGPVLANSFGELPERAKLSLSSEKLIKAGFKFKYRQLEEIYDETIKYALATGLLAPK
>DJ01Gene47735
MERRSKVCVTGASGYLGSWLVKKLLKNGHVVHATLRNLEDKSKTQLLKSFPGANTRMHLFEAELYNPLTFEAAIQGCEFVFLLATPLQHNANSQYKDTTQAAVAAVRSILQLCERSGTVKRVIYTGSVTAASPLKEDGMGFKDFIDESHWTPLHLAFAYCEDFEKSYICSKTESEKEVLSYNYKEGIKKEFEVVSLVCALVGGDTVLSIVPLSVRCTISPLTGDKVNHRQMKFLQALLGSVPLVHIKDVCEAHIFCMEKPSMAGRFLLASAYPTMQEIVDHYTQNYPKLRAIKEVEGDGHGIGCRSTKLADMGFKFRYDVKQILDASVETAKRLGCLDELA
>DJ01Gene51260
MTSEGKLACVTGATGFIASALIKQLLEKGYAVNATVRYPENWEKLSPLREMQNLGSLKIFRADLRDEGSFDEAVAGSDYVFYVAAPLNLHTDDPERDYGGFRIARGRRGFRGPRPRRLRXTGATGFIASALIKQLLEKGYAVNATVRYPEIWEKLSPLREMQNLGSLKIFRADLRDEGSFDEAVAGSDYVFYVAAPLNLHTDDPESCRGLKETSNFAEAETEAEVARTMVEAAEAKVEAAEAETKAEVAGTVAEAAEAKAEAETEAEVARTMAEATEAVAEAEAEAAEVTEMAEAVKAETEAEVAGTVVEAVEVKVKAACRGCSDMLSLC
>DJ01Gene51258
MTNEGKLACVTGATGFIASALIKQLLEKGYAVNATVRDPENWEKLSPLREMQNLGSLKIFRADLRDEGSFDEAVAGSDYVFYVAAPVNLHTDDPENELIKPAVQGVLNVMKSCLKAKSVKRFVLTSSAAAVSIKRPAKSSLTLDEESWSDMEFLTIDKPPTWGYGVSKMLTEREALKFAQENNISLVTIIPSLTIGPAPTATFKRGRHSHGPELANR
>DJ01Gene65722
MAAENSEKLSQLKEMHNLGSLKIFQANLRDEGSFDAAVAGCDYVFYVAAPVILNANDPENELIKPAVQGILNVMKSCLKANSVKRFVLTSSAAAVSIKQPTKNNLMLDEESWSDMEFLTDNKLPTCAYGVSKMLTERREALRFAQENNITLVTMIPALTIGPALASSQFCRKHRHRHGPVLANSFGELPERAKLSLSSEKLIKAGFKFKYRQLEEIYDETIKYALATGLLAPK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University