Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Cuscuta australis
Species name
Cuscuta australis is a species of eudicot in the family Convolvulaceae (morning-glory family).
Species info
Gene sequence info
Cuscuta_australis.HIDH.fa
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>C002N0155M0.1
MASSPVLLAILFSFAALSFYSPLVAGADDGGQVVASVPPLIFVFRNGTINRPLDQKKLPPSPRDPATGVSSRDITISGRIPARIYLPRLESRSEKLPVLIWYHGGGFCMGSAFASGDHQFLNILASKSKILAVSVDYRIAPEHLLPAAYEDSWAAVRWVASHAVPGSARTDPALLQHGNFSRVFLGGDSSGANIVHNMIVRSAGEKLPGNLRIFGGILTHPFFWGSKDGDTQSFGYRDWSFAYPAAPGGIDNPMINPFSKRITGLRTSRIFVSIAELDGLRAKGVEYVNAVNGSGWRGEIELLEVAGVGHSFYLNHIHSIKAFYLITQIAKFINH
>C003N0366E0.1
MSLLHEAPGYLQVFSDGTVKRFTPEIASASPADPTNGFKSKDVVIGSSPEPITGRIYVPDGEQEAASDDELLAVIFYFHGGGFCIGSTSWLGYHQFLGSLSVRSKSIVVSVDYRLAPENKLPIAYHDCYSALGWVRANQKVETFLERSDLSRIFLAGDSAGGNIVHQVTIQSLKAINNGITIKGIMLIHPYFGSEKRTKLETKAGSAANVAMNDMFWRLSLPEGCNRDFYGCNFDNNNATGLSADEWLRFPAVIVFVAGLDFLKERGVMYTEYLRRKTVKWVELVEAEEEGHVFHVFHPDSEATRLLQEKMTQFMYAV
>C036N0127M0.1
MKYHPSLSLGKHPIHNPHSIAPFSLRRRDCEVAVGNPASMSKNLVYKDGRVERLCGTDIVPAGFDAGTGVQSKDIEISQAPRVSVRLYLPETAGRRKLPLLIYFHGGGLVTESAFSPMYQTPLNLLASEARIVIVSVDYRLAPEHPLPAAYEDAWVALQWVANNTEDEWLREHADFSRVFLGGDSVGANIAHNLAVRAGSGRNVDRVKLEGLFFNCPCFWGTDRIGDEGEHELICSFLENMWRVAHPTATGMDDPNINPGKDPELGKMGCKRVIIYVAEKDPSKHRGWLYKEALDGVGWGGEVEVVEVKGESHIFNLLNPMCENAMAMLRKLASFFHPHSNSA
>C036N0126M0.1
MGDDADSSDLRLFHDFPTLMRVYKDGRVERLAGNDVVPPDPDVETGVRCKDIVISPDPKVSARIFLPKTAAPGRKLPLLVYFHGGCFLIESAFSPTYKKHLCLVSAESDAVIVSVDYRLAPEHPIPAAFDDSWLALNWVASHSTGAGGEEWLRSYTDFDRVFLGGDSAGATIAHRMGIRVGLEGLNGIEIGGIFLNCPFFWGKDPIADEAENPEVRSLLDDIWKFANPTTTGTDDPLLNPTMDPELANLGCKKVLVYVAEKDPMKHRGRLYAAALGKRGWPGAAEVVEAEGEHHVFNLFSPTSDNSMAMVKKLASFFNSEPFLNVVAGEIKV
>C005N0623E0.1
MASTTSAKVVHDFHPIFRIYDDGRVERVYTYVSVPASDNPETGVRSRDAVVVPEDNVWVRLYLPRTNDDGQRFPVVVYFHGGAFTVESASSTTYDNYLHSLTAKANVISVSIDYRLAPEHRLPACYEDCWAAIQWVAQGSDPWLKSHADLDRVFFAGDSAGGNIAHNMMARASGEDCLKPAGMVLDHPYFGDGKPDKLWEFIYPESSGVDDPMRDPMSSPGILSGMGCSKVMVILSEKDFVREGGLRYYEALKKSGWGGDLELLDVEGEEHVFHLQKPDCEKAGLVMDRVVAFLNRA
>C056N0032E0.1
MSSTADETAVQPVHVSPYFTLYNDGRVARHGEPECVQACDDPDAAVRSKDVVVQPETGVSVRLFLPKLTGTGKKLPLVIYIHGGAFVICSTKWAAYHNFITSMVEKATVVAASVEYRLAPEHPLPIAYDDSWVAFRWIMSHAEGRGPDPWLNAHADFGEIFLGGESAGANIAHDVAIRAGSSEDFRDGKISGLFLVHPFFGGEEEDKLYRFLCPESSGGYDDPRLNPAADPRLGRMPCKRVLFHMAGDDFLGARARLYFQELKKSEWKGEAEIVEIEGEGHAFHLTDPSNPKAATLIHDLVSFFNQS
>C000N0850M0.1
MIGEEIAVDLSPFIRVYKGGRVERLFASPRVAPSASEDDSETGGVSSKDVTISADVSARIYLPKPPAAGKLPILVYFHFGGFCLESAFSFRNHRYLNALVSESGVVAVSVEYRLAPEHPLPAAYDDAFEALRWVASHAAGDQNGFLDSRMPVSQRVQRPALESWLVDHGDIGRIFLAGDSAGGNIVHNVAMRAGKQGIPALAGGILCFPYFWGSTEKGGKQGRLSKTWDLVCPTAEGGIDSPMINPTAENAPSLSGLDRCPKILVCVAEKDDLREIGVRYVGAVKRSGWKGKIDILDVEGEGHCFQVLNPDSENAKRRIASFISA
MASSPVLLAILFSFAALSFYSPLVAGADDGGQVVASVPPLIFVFRNGTINRPLDQKKLPPSPRDPATGVSSRDITISGRIPARIYLPRLESRSEKLPVLIWYHGGGFCMGSAFASGDHQFLNILASKSKILAVSVDYRIAPEHLLPAAYEDSWAAVRWVASHAVPGSARTDPALLQHGNFSRVFLGGDSSGANIVHNMIVRSAGEKLPGNLRIFGGILTHPFFWGSKDGDTQSFGYRDWSFAYPAAPGGIDNPMINPFSKRITGLRTSRIFVSIAELDGLRAKGVEYVNAVNGSGWRGEIELLEVAGVGHSFYLNHIHSIKAFYLITQIAKFINH
>C003N0366E0.1
MSLLHEAPGYLQVFSDGTVKRFTPEIASASPADPTNGFKSKDVVIGSSPEPITGRIYVPDGEQEAASDDELLAVIFYFHGGGFCIGSTSWLGYHQFLGSLSVRSKSIVVSVDYRLAPENKLPIAYHDCYSALGWVRANQKVETFLERSDLSRIFLAGDSAGGNIVHQVTIQSLKAINNGITIKGIMLIHPYFGSEKRTKLETKAGSAANVAMNDMFWRLSLPEGCNRDFYGCNFDNNNATGLSADEWLRFPAVIVFVAGLDFLKERGVMYTEYLRRKTVKWVELVEAEEEGHVFHVFHPDSEATRLLQEKMTQFMYAV
>C036N0127M0.1
MKYHPSLSLGKHPIHNPHSIAPFSLRRRDCEVAVGNPASMSKNLVYKDGRVERLCGTDIVPAGFDAGTGVQSKDIEISQAPRVSVRLYLPETAGRRKLPLLIYFHGGGLVTESAFSPMYQTPLNLLASEARIVIVSVDYRLAPEHPLPAAYEDAWVALQWVANNTEDEWLREHADFSRVFLGGDSVGANIAHNLAVRAGSGRNVDRVKLEGLFFNCPCFWGTDRIGDEGEHELICSFLENMWRVAHPTATGMDDPNINPGKDPELGKMGCKRVIIYVAEKDPSKHRGWLYKEALDGVGWGGEVEVVEVKGESHIFNLLNPMCENAMAMLRKLASFFHPHSNSA
>C036N0126M0.1
MGDDADSSDLRLFHDFPTLMRVYKDGRVERLAGNDVVPPDPDVETGVRCKDIVISPDPKVSARIFLPKTAAPGRKLPLLVYFHGGCFLIESAFSPTYKKHLCLVSAESDAVIVSVDYRLAPEHPIPAAFDDSWLALNWVASHSTGAGGEEWLRSYTDFDRVFLGGDSAGATIAHRMGIRVGLEGLNGIEIGGIFLNCPFFWGKDPIADEAENPEVRSLLDDIWKFANPTTTGTDDPLLNPTMDPELANLGCKKVLVYVAEKDPMKHRGRLYAAALGKRGWPGAAEVVEAEGEHHVFNLFSPTSDNSMAMVKKLASFFNSEPFLNVVAGEIKV
>C005N0623E0.1
MASTTSAKVVHDFHPIFRIYDDGRVERVYTYVSVPASDNPETGVRSRDAVVVPEDNVWVRLYLPRTNDDGQRFPVVVYFHGGAFTVESASSTTYDNYLHSLTAKANVISVSIDYRLAPEHRLPACYEDCWAAIQWVAQGSDPWLKSHADLDRVFFAGDSAGGNIAHNMMARASGEDCLKPAGMVLDHPYFGDGKPDKLWEFIYPESSGVDDPMRDPMSSPGILSGMGCSKVMVILSEKDFVREGGLRYYEALKKSGWGGDLELLDVEGEEHVFHLQKPDCEKAGLVMDRVVAFLNRA
>C056N0032E0.1
MSSTADETAVQPVHVSPYFTLYNDGRVARHGEPECVQACDDPDAAVRSKDVVVQPETGVSVRLFLPKLTGTGKKLPLVIYIHGGAFVICSTKWAAYHNFITSMVEKATVVAASVEYRLAPEHPLPIAYDDSWVAFRWIMSHAEGRGPDPWLNAHADFGEIFLGGESAGANIAHDVAIRAGSSEDFRDGKISGLFLVHPFFGGEEEDKLYRFLCPESSGGYDDPRLNPAADPRLGRMPCKRVLFHMAGDDFLGARARLYFQELKKSEWKGEAEIVEIEGEGHAFHLTDPSNPKAATLIHDLVSFFNQS
>C000N0850M0.1
MIGEEIAVDLSPFIRVYKGGRVERLFASPRVAPSASEDDSETGGVSSKDVTISADVSARIYLPKPPAAGKLPILVYFHFGGFCLESAFSFRNHRYLNALVSESGVVAVSVEYRLAPEHPLPAAYDDAFEALRWVASHAAGDQNGFLDSRMPVSQRVQRPALESWLVDHGDIGRIFLAGDSAGGNIVHNVAMRAGKQGIPALAGGILCFPYFWGSTEKGGKQGRLSKTWDLVCPTAEGGIDSPMINPTAENAPSLSGLDRCPKILVCVAEKDDLREIGVRYVGAVKRSGWKGKIDILDVEGEGHCFQVLNPDSENAKRRIASFISA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University