Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Cuscuta australis
Species name
Cuscuta australis is a species of eudicot in the family Convolvulaceae (morning-glory family).
Species info
Gene sequence info
Cuscuta_australis.4CL.fa
Download
>C055N0075E0.1
MGAPTEQAAGDFIFRSKLPDIHIPNHLPLHSYCFQNISQLRDRPCLINGSDDRIYTYAEVELTCRRVASGLHKQGINRGDTVMILLPNSPEYIFTFLGASYGGAIATMANPMFTPAEVVKQVKASNARLIVTQACNVNKVKEYAGEREIKVVCTDAAVDGCLHFSELAGADEGEAPAVEADPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQHVEGENPHFYLHGEDALLCVLPFFHIYSMSIFLCGLRVGAQILIMQRFEIAPFFELIQKYKVTVTPLVPPIVLAISKSPLVDDYDLSSVRVVMSGAAPLGKELQDTLREKFSNARFGQGYGMTEGGSVLAMGLAFAKEPFEIKSGSVGTVVRNAELKIVDPETGSSLPRNQPGEICIRGHQIMKGYLNDEEATKRTIDKEGWLHTGDVGYIDEDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPLISDAAVIPMKDEDAGEVPVAFVVKLNGCNITEDDVKDFVSKKVIFYKRIRNVFFVEAVPKSPSGKILRKNLRARLEAQ
>C024N0271E0.1
MGSQTRPCDDVIFRSKLPDIDIPTHLPLHLYCFENVSGDRRCLIDGPTGRVYTYGEVELMSRKVGSGLRRQGIMQHDTVMILLPNSPEYVFTFLGASFIGAVSTMANPLFTAAEVVKQAKAAGAKLVVTLACYVHKLRDFAREHGAKVVCVEPEAQEGCVSFSELAEADEREMPEAEIDPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGPNPNLYFHNEDVILCVLPLFHIYSLNSVLLCGLRVGAAILIMPKFEIVPFFELIEKYKVTIGPFVPPIVLAIAKSPYVGNYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAEMKILDPDTGASLTRNRPGEICIRGDQIMKGYLNDIEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGYQVAPAELEALLLNHPLISDAAVVSMKDEQSGEVPVAFVVRSYGSVITEEEIKDFVSKQVIFYKRIKKVFFVDLVPKSPAGKILRKELRAKLAIGVQA
>C019N0188E0.1
MGSEVGQQAMAKPNEDHIFRSKYPSVQVPDDMTLPDFVLHNIEPYTNNVALVDSTTGKEYTYGQVLRDIRRFAKALRSLGLRKGRVVVVVLPNVAEYAIIALGIMAAGGVISGANPASHSSELKKQVEVADAKLLVTDAPTCHKVKDLGIPVIVVDEEQVQGTINWDELLQAADRASNDLTIPEDEVVKQSDLCALPFSSGTTGVSKGVMLTHRNVVANLCSSLFSVGPELIGNVVILGLIPFFHIYGLVGICCATMRNKGRVVVMRRYELGAFLDALITHEVNFAPIVPPIILGLVKNPIVDTYDLTKLKLKSIMTAAAPLAPEILNEFQKKFPDVQVHEAYGMTEHSCITLTHGDPRMDHAIAKKNSVGFILPNLEVKFIDPESGLSLPKNTPGEICVRSQCVMKGYYNNEYETALTIDKDGWLHTGDIGYIDDDGDIFIVDRIKELIKFKGFQVAPAELEATLLSHPSVEDAAVVGLPDEEAGEIPAACVVLSHGAKDTGEDIKNYVASCVAHYKRVRVLQFVDAIPKSPSGKIMRRLIKEQMVKNLASA
>C043N0158E0.1
MEKSGYCRDGIYRSLRPPLILPKDPDLSMVSFLFRNISQYPDQPAIQDADSGETLTFAQFKSEVSKVAHGLVHRLGIRKNDVVLIFSPNSIPFPLCFFGSIAAGAIASTVNPTYTVPELSKQIKDCSPKLIVTVPQLLDKIKGFNLPVLLLGPENPNRSGLNSSPGLTFFTDLVRDSRQLDLDSVSIKQSDTAALLYSSGTTGVSKGVVLTHGNFVALSQMVNADQDAAREMHNVFLCMLPMFHVFGLSVILYSQLVRGNTVVSMGKFDLEMVLKNVDKYRVTHMWVVPPIILAFAKSSVVKKYSLTSLKHIGSGAAPLGKDLMEECAKNFPQAALVQGYGMTETCGVISKENPSIGMRHSGSAGMLVPGLEARIVSVSNPQSLPPGQLGEIWVRGPNVMKGYYKNPEATKATIDKQGWLHTGDLGYFDVEGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPDILDAVVIPYPDTEAGEVPVAYVVRSPNSSLTEEDVKKFIADQVAPFKRLRQVTFINSVPKSASGKILRRELIEKVRSKL
MGAPTEQAAGDFIFRSKLPDIHIPNHLPLHSYCFQNISQLRDRPCLINGSDDRIYTYAEVELTCRRVASGLHKQGINRGDTVMILLPNSPEYIFTFLGASYGGAIATMANPMFTPAEVVKQVKASNARLIVTQACNVNKVKEYAGEREIKVVCTDAAVDGCLHFSELAGADEGEAPAVEADPEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQHVEGENPHFYLHGEDALLCVLPFFHIYSMSIFLCGLRVGAQILIMQRFEIAPFFELIQKYKVTVTPLVPPIVLAISKSPLVDDYDLSSVRVVMSGAAPLGKELQDTLREKFSNARFGQGYGMTEGGSVLAMGLAFAKEPFEIKSGSVGTVVRNAELKIVDPETGSSLPRNQPGEICIRGHQIMKGYLNDEEATKRTIDKEGWLHTGDVGYIDEDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPLISDAAVIPMKDEDAGEVPVAFVVKLNGCNITEDDVKDFVSKKVIFYKRIRNVFFVEAVPKSPSGKILRKNLRARLEAQ
>C024N0271E0.1
MGSQTRPCDDVIFRSKLPDIDIPTHLPLHLYCFENVSGDRRCLIDGPTGRVYTYGEVELMSRKVGSGLRRQGIMQHDTVMILLPNSPEYVFTFLGASFIGAVSTMANPLFTAAEVVKQAKAAGAKLVVTLACYVHKLRDFAREHGAKVVCVEPEAQEGCVSFSELAEADEREMPEAEIDPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGPNPNLYFHNEDVILCVLPLFHIYSLNSVLLCGLRVGAAILIMPKFEIVPFFELIEKYKVTIGPFVPPIVLAIAKSPYVGNYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAEMKILDPDTGASLTRNRPGEICIRGDQIMKGYLNDIEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGYQVAPAELEALLLNHPLISDAAVVSMKDEQSGEVPVAFVVRSYGSVITEEEIKDFVSKQVIFYKRIKKVFFVDLVPKSPAGKILRKELRAKLAIGVQA
>C019N0188E0.1
MGSEVGQQAMAKPNEDHIFRSKYPSVQVPDDMTLPDFVLHNIEPYTNNVALVDSTTGKEYTYGQVLRDIRRFAKALRSLGLRKGRVVVVVLPNVAEYAIIALGIMAAGGVISGANPASHSSELKKQVEVADAKLLVTDAPTCHKVKDLGIPVIVVDEEQVQGTINWDELLQAADRASNDLTIPEDEVVKQSDLCALPFSSGTTGVSKGVMLTHRNVVANLCSSLFSVGPELIGNVVILGLIPFFHIYGLVGICCATMRNKGRVVVMRRYELGAFLDALITHEVNFAPIVPPIILGLVKNPIVDTYDLTKLKLKSIMTAAAPLAPEILNEFQKKFPDVQVHEAYGMTEHSCITLTHGDPRMDHAIAKKNSVGFILPNLEVKFIDPESGLSLPKNTPGEICVRSQCVMKGYYNNEYETALTIDKDGWLHTGDIGYIDDDGDIFIVDRIKELIKFKGFQVAPAELEATLLSHPSVEDAAVVGLPDEEAGEIPAACVVLSHGAKDTGEDIKNYVASCVAHYKRVRVLQFVDAIPKSPSGKIMRRLIKEQMVKNLASA
>C043N0158E0.1
MEKSGYCRDGIYRSLRPPLILPKDPDLSMVSFLFRNISQYPDQPAIQDADSGETLTFAQFKSEVSKVAHGLVHRLGIRKNDVVLIFSPNSIPFPLCFFGSIAAGAIASTVNPTYTVPELSKQIKDCSPKLIVTVPQLLDKIKGFNLPVLLLGPENPNRSGLNSSPGLTFFTDLVRDSRQLDLDSVSIKQSDTAALLYSSGTTGVSKGVVLTHGNFVALSQMVNADQDAAREMHNVFLCMLPMFHVFGLSVILYSQLVRGNTVVSMGKFDLEMVLKNVDKYRVTHMWVVPPIILAFAKSSVVKKYSLTSLKHIGSGAAPLGKDLMEECAKNFPQAALVQGYGMTETCGVISKENPSIGMRHSGSAGMLVPGLEARIVSVSNPQSLPPGQLGEIWVRGPNVMKGYYKNPEATKATIDKQGWLHTGDLGYFDVEGQLYVVDRIKELIKYKGFQVAPAELEGLLVSHPDILDAVVIPYPDTEAGEVPVAYVVRSPNSSLTEEDVKKFIADQVAPFKRLRQVTFINSVPKSASGKILRRELIEKVRSKL
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