Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Cucurbita pepo
Species name
Cucurbita pepo is a species of eudicot in the family Cucurbitaceae (cucumber family).
Species info
Gene sequence info
Cucurbita_pepo.CHS.fa
Download
>rna-XM_023671079.1
MPHLSSPSLSDLIHSGLYTHPILFLFKLPSMSKTSCEGSAMLHHERARRAPTPGKAAILAIGKAFPSQLVPQECLVEGYIRDTKCVDATVKEKLERLCKTTTVKTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRPVEDITHIVYVSSSEIRLPGGDLYIASRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDLAENNPGSRILLTTSETTILGFRPPNNARPYDLVGAALFGDGAAAVIIGADPVAGQESPFMELNYAIQQFLPDTHYVIDGRLSEEGINFKLGRDLPQRIDDNIEGFCRKLMGKGKLVDFNELFWAVHPGGPAILNKLERTLRLKSEKLECSRKALMEYGNVSSNTIFYVIEKMREKLKREDGEEWGLALAFGPGITFEGILIRSL
>rna-XM_023672486.1
MASVADIRKAQRANGPATIFAIGTAVPPNIVLQSDYPDYYFRITNSEHMTVLKEKFVRMCEKSMITKRHMYLTEKILKENPNMCEYLAPSLDTRQDMVVVEVPKLGKDAAVKAIKEWGQPKSKITHLVFCTTSGIEMPGADYRLMKLLGLHPSVRRYMMYQQGCYGGGAVLRLAKDIAENNKGARVLVVCSEITAITFRGPSETHLDSMVGQALFGDGASAVIIGSDPDLAVEKPLYELVWAGATVLPDSEGAIDGHLREVGLTFHLLKDVPSLISTNIETSLKEAFTPLGISDWNSIFWITHPGGPAILDLVEAKLGLKEEKMKASREILREYGNMSSSCVGFIMDQMRKNSVEEGASTTGEGLDWGVLFGFGPGLTVETVVLHSVPLK
>rna-XM_023672485.1
MASVAEIRDAQRAKGPATVLAIGTATPPNSVLQSDYPDYYFRITKSEHMTVLKEKFVRMCEKSMIRKRHMYLTEEILKENSNMCAYMEPSLDARQDMVVVEVPKLGKDAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLMKLLGLRPSVKRYMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAITFRGPSETHLDSMVGQALFGDGASAMIIGSDPDLAVEKPLYEMVWTGATVLPDSEGAIDGHLREVGLTFHLLKDVPGLISTNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEVKLGLKEEKMKATREILREYGNMSSACVGFIMDQMRKNSLEEGAATTGEGLEWGVLFGFGPGLTVETVVLHSVALK
>rna-XM_023674062.1
MGKGNGALGASKGKANPGRASILALGKAFPPQLVLQDYLVDSYFKDTSCDDLDLKRKLTRLCKTTSVKTRYVVMSEEILKKHPELAMEGQATIKQRLEICNKAVTDMAIEASQAAIKNWGRPLSDITHLVYVSSSEARLPGGDLFLARGLGLSPHTQRLMLYFMGCSGGVAGLRVAKDLAENNPGSRVLLVTSETTIIGYKPPSAHRPYDLVGVALFGDGAGAMLIGADPVLAIERPLFELHTATQKFIPNTQNVIDGRMSEEGISFTIARELPQIIEDNIGSFCETFLQTVGLHEKEYNKIFWAVHPGGPAILNKLEKRLELLPKKLKASRRALMDYGNASSNTIVYVLEYMVDESLKTKMGGGEIEEWGLILAFGPGISFEGILARNLSV
>rna-XM_023683664.1
MAVISSFKDGAAVVFRRQSSNMHRRLPSLRCYSSRLTEAETKSLNKTKKARDMARMINSKPWSNDLESSLASFSPSLSKTTVLQTLGFLRDPSKALKFFNWAQEMGYAHTEQSYFSMLEILGRNRHLNTARNFLFSIEKRSRGAVKLEARFFNSLMRNFSRAGLFQESINLFTTMKSHGVSPSIVTFNSLLTILLKRGRTNMAKNVYDEMLSTYGVTPDTFTFNILIRGFCMNGMVDEGFRIFKDLSRFGCEPDVITYNTLVDGLCRGGRVTIAYNVVKAMGKKSVDLNPNVVTYTTLIRGYCAKREINNALAVFEEMVNLGLKANNITYNTLIKGLCEAEKFEKVKEILEATAVDGTFSPDTCTFNILMHCHCDAGNLDEALRVFERMTKLKIQPDSATYSVLIRSLCEGKYYEKAENLLDKLLEKRILLSDDGCKPLVAAYNPILKYLCENGKAKKAETVFRQLMRRGTQDPPSYKTLIMGHCNEGTFESGYELLVLMLRKDFLPDMEVYESLINGFLHKDKPLLALQTLEKMLRSSHLPESSTFHSILEKLLEQGNASESASLIQLMLDKNIRQNLGFSTGCIRLLFEAGINDKAFQIVRMLYGNGYSVKMEELILFLCHCKKVIEASKMLLFSLESHQAVDIDVCSTVIFHLCQINKLSEAFGLYYKLVEMGVHQRLSCQNQLKVSLETGGKFEEAEFVSKRMEPQLKCKTNEAEGTTIFLKQLAEVIWSWIYQMGLVLQTLIGFIQVFTDKGYKHISFKLPNMSKMSCEGPAKLDHARARRVPTPGKATILAIGKAFPSQLVPQECLVEGYIRDTKCVDATIKEKLERLCKTTTVKTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRSVEDITHIVYVSSSEIRLPGGDLYIANRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNNERPYDLVGAALFGDGAAGVIIGADPVLGQESPFMELNYAIQQFLPDTHNVIDGRLSEKGINFILGRDLPQRIDENIEEFCRKLMGKGKLVEFNELFWAVHPGGPAILNKLESTLRLKSDKLECSRKALMDYGNVSSNTIFYVIEKMREKLKREDGEEWGLALAFGPGITFEGILIRSL
>rna-XM_023692008.1
MTTIDKILKDQRAEGAATVMAIGTAVPSNWVQQTTYPDYYFRITNNEHKTELKHKFKRICEKSTIRKRHMLLTEELLKQNPKICAHEAPSLDSRQDIAVVEVPKLGKQAAVNAIREWGRPTADITHLIFCTSSGIDMPGADYRLTKLLGLRPSVKRFMIYQQGCFAGATVLRLVKDLAENNRAARVLAVCSEITAVTFRGPSDSHLDGLVGQALFGDGAAAIIVGSDPVPGLERPIFEIISAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLVSKNIRRILLEAFGPLGLSNWNSIFWIVHPGGPAILDQIEMELGLGPDKLRSSRHVLREYGNMSSACVFFILDEMRKKSSQNGLKTTGEGLEWGVLFGFGPGLTVETVALRSVAI
>rna-XM_023697946.1
MSEEILKKYPELAMEGQATIKQRLEICNKAVTDMAIEASQAAIKNWGRPVSDITHLVYVSSSEARLPGGDLFLAKGLGLSPHTQRLMLYFMGCSGGVAGLRVAKDLAENNPGSRVLLVTSETTIIGYKPPSAKRPYDLVGVALFGDGAGAMLIGTDPVFGIERPLFELHTATQKFIPNTQNIIDGRLSEEGISFTIARDLPQIIEDNIENFCEAFLQTLGLQEKEYNKMFWAVHPGGPAILSRLEKRLELLPEKLTASRRALMDYGNASSNTIVYVLEYMVEESLKKKMGGGETEEWGLILAFGPGISFEGILTRNLAVGA
>rna-XM_023658687.1
MFVHRHAPQLDFGVARQLQQLENNNILIIGQLSLKVILVGRDHCGLQRPIFEILSERPIDGHSREVGLTPRCFGPLGLSDWNSTSGSRILVGRRFRPDQDGVGPRARKVAGVEARDSGVRMRKKSSENGLKTAGDGLEWSLVIEVGPGLTVETMLCASWA
MPHLSSPSLSDLIHSGLYTHPILFLFKLPSMSKTSCEGSAMLHHERARRAPTPGKAAILAIGKAFPSQLVPQECLVEGYIRDTKCVDATVKEKLERLCKTTTVKTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRPVEDITHIVYVSSSEIRLPGGDLYIASRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDLAENNPGSRILLTTSETTILGFRPPNNARPYDLVGAALFGDGAAAVIIGADPVAGQESPFMELNYAIQQFLPDTHYVIDGRLSEEGINFKLGRDLPQRIDDNIEGFCRKLMGKGKLVDFNELFWAVHPGGPAILNKLERTLRLKSEKLECSRKALMEYGNVSSNTIFYVIEKMREKLKREDGEEWGLALAFGPGITFEGILIRSL
>rna-XM_023672486.1
MASVADIRKAQRANGPATIFAIGTAVPPNIVLQSDYPDYYFRITNSEHMTVLKEKFVRMCEKSMITKRHMYLTEKILKENPNMCEYLAPSLDTRQDMVVVEVPKLGKDAAVKAIKEWGQPKSKITHLVFCTTSGIEMPGADYRLMKLLGLHPSVRRYMMYQQGCYGGGAVLRLAKDIAENNKGARVLVVCSEITAITFRGPSETHLDSMVGQALFGDGASAVIIGSDPDLAVEKPLYELVWAGATVLPDSEGAIDGHLREVGLTFHLLKDVPSLISTNIETSLKEAFTPLGISDWNSIFWITHPGGPAILDLVEAKLGLKEEKMKASREILREYGNMSSSCVGFIMDQMRKNSVEEGASTTGEGLDWGVLFGFGPGLTVETVVLHSVPLK
>rna-XM_023672485.1
MASVAEIRDAQRAKGPATVLAIGTATPPNSVLQSDYPDYYFRITKSEHMTVLKEKFVRMCEKSMIRKRHMYLTEEILKENSNMCAYMEPSLDARQDMVVVEVPKLGKDAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLMKLLGLRPSVKRYMMYQQGCYAGGTVLRLAKDLAENNKGARVLVVCSEITAITFRGPSETHLDSMVGQALFGDGASAMIIGSDPDLAVEKPLYEMVWTGATVLPDSEGAIDGHLREVGLTFHLLKDVPGLISTNIEKSLKEAFTPLGISDWNSIFWIAHPGGPAILDQVEVKLGLKEEKMKATREILREYGNMSSACVGFIMDQMRKNSLEEGAATTGEGLEWGVLFGFGPGLTVETVVLHSVALK
>rna-XM_023674062.1
MGKGNGALGASKGKANPGRASILALGKAFPPQLVLQDYLVDSYFKDTSCDDLDLKRKLTRLCKTTSVKTRYVVMSEEILKKHPELAMEGQATIKQRLEICNKAVTDMAIEASQAAIKNWGRPLSDITHLVYVSSSEARLPGGDLFLARGLGLSPHTQRLMLYFMGCSGGVAGLRVAKDLAENNPGSRVLLVTSETTIIGYKPPSAHRPYDLVGVALFGDGAGAMLIGADPVLAIERPLFELHTATQKFIPNTQNVIDGRMSEEGISFTIARELPQIIEDNIGSFCETFLQTVGLHEKEYNKIFWAVHPGGPAILNKLEKRLELLPKKLKASRRALMDYGNASSNTIVYVLEYMVDESLKTKMGGGEIEEWGLILAFGPGISFEGILARNLSV
>rna-XM_023683664.1
MAVISSFKDGAAVVFRRQSSNMHRRLPSLRCYSSRLTEAETKSLNKTKKARDMARMINSKPWSNDLESSLASFSPSLSKTTVLQTLGFLRDPSKALKFFNWAQEMGYAHTEQSYFSMLEILGRNRHLNTARNFLFSIEKRSRGAVKLEARFFNSLMRNFSRAGLFQESINLFTTMKSHGVSPSIVTFNSLLTILLKRGRTNMAKNVYDEMLSTYGVTPDTFTFNILIRGFCMNGMVDEGFRIFKDLSRFGCEPDVITYNTLVDGLCRGGRVTIAYNVVKAMGKKSVDLNPNVVTYTTLIRGYCAKREINNALAVFEEMVNLGLKANNITYNTLIKGLCEAEKFEKVKEILEATAVDGTFSPDTCTFNILMHCHCDAGNLDEALRVFERMTKLKIQPDSATYSVLIRSLCEGKYYEKAENLLDKLLEKRILLSDDGCKPLVAAYNPILKYLCENGKAKKAETVFRQLMRRGTQDPPSYKTLIMGHCNEGTFESGYELLVLMLRKDFLPDMEVYESLINGFLHKDKPLLALQTLEKMLRSSHLPESSTFHSILEKLLEQGNASESASLIQLMLDKNIRQNLGFSTGCIRLLFEAGINDKAFQIVRMLYGNGYSVKMEELILFLCHCKKVIEASKMLLFSLESHQAVDIDVCSTVIFHLCQINKLSEAFGLYYKLVEMGVHQRLSCQNQLKVSLETGGKFEEAEFVSKRMEPQLKCKTNEAEGTTIFLKQLAEVIWSWIYQMGLVLQTLIGFIQVFTDKGYKHISFKLPNMSKMSCEGPAKLDHARARRVPTPGKATILAIGKAFPSQLVPQECLVEGYIRDTKCVDATIKEKLERLCKTTTVKTRYTVMCKEILDKYPELVTEGSPTIRQRLEIANPAVVEMATEASKACIKEWGRSVEDITHIVYVSSSEIRLPGGDLYIANRLGLKNDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNNERPYDLVGAALFGDGAAGVIIGADPVLGQESPFMELNYAIQQFLPDTHNVIDGRLSEKGINFILGRDLPQRIDENIEEFCRKLMGKGKLVEFNELFWAVHPGGPAILNKLESTLRLKSDKLECSRKALMDYGNVSSNTIFYVIEKMREKLKREDGEEWGLALAFGPGITFEGILIRSL
>rna-XM_023692008.1
MTTIDKILKDQRAEGAATVMAIGTAVPSNWVQQTTYPDYYFRITNNEHKTELKHKFKRICEKSTIRKRHMLLTEELLKQNPKICAHEAPSLDSRQDIAVVEVPKLGKQAAVNAIREWGRPTADITHLIFCTSSGIDMPGADYRLTKLLGLRPSVKRFMIYQQGCFAGATVLRLVKDLAENNRAARVLAVCSEITAVTFRGPSDSHLDGLVGQALFGDGAAAIIVGSDPVPGLERPIFEIISAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLVSKNIRRILLEAFGPLGLSNWNSIFWIVHPGGPAILDQIEMELGLGPDKLRSSRHVLREYGNMSSACVFFILDEMRKKSSQNGLKTTGEGLEWGVLFGFGPGLTVETVALRSVAI
>rna-XM_023697946.1
MSEEILKKYPELAMEGQATIKQRLEICNKAVTDMAIEASQAAIKNWGRPVSDITHLVYVSSSEARLPGGDLFLAKGLGLSPHTQRLMLYFMGCSGGVAGLRVAKDLAENNPGSRVLLVTSETTIIGYKPPSAKRPYDLVGVALFGDGAGAMLIGTDPVFGIERPLFELHTATQKFIPNTQNIIDGRLSEEGISFTIARDLPQIIEDNIENFCEAFLQTLGLQEKEYNKMFWAVHPGGPAILSRLEKRLELLPEKLTASRRALMDYGNASSNTIVYVLEYMVEESLKKKMGGGETEEWGLILAFGPGISFEGILTRNLAVGA
>rna-XM_023658687.1
MFVHRHAPQLDFGVARQLQQLENNNILIIGQLSLKVILVGRDHCGLQRPIFEILSERPIDGHSREVGLTPRCFGPLGLSDWNSTSGSRILVGRRFRPDQDGVGPRARKVAGVEARDSGVRMRKKSSENGLKTAGDGLEWSLVIEVGPGLTVETMLCASWA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University