Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Cucumis melo
Species name
Muskmelon (Cucumis melo) is a species of eudicot in the family Cucurbitaceae (cucumber family).
Species info
Gene sequence info
Cucumis_melo.HIDH.fa
Download
>rna-XM_008447176.2
MTKGKSLVLDVSGWLRLYDDGSVDRTWTGPPEVKFVAESVPPHDEFIDGVAVRDLVIDQNSGLRVRIYLPEVKCGGEVKKLPVVVHFHGGGFCISEADWFMYYHTYTNLAKSAEAICVSVYLRRAPEHRLPAQIEDGFSALKWLQSVALGNEIEPWIVEKADFNRVFLIGDSSGGNLVHSVAARAGETDLAPLKLAGGIPIHPGFVRAKRSKSEIENPQSPFLTLDMVDKFLNLALPVGSSKDHPITCPMGSAAPPLENLNLPPFLLCIAEKDLVIDTEMEYYEAMKAANKEVEILMSKEMGHSFYLNKIALKLDPETAAESDRLFAGIARFIKQH
>rna-XM_008446418.2
MTFPFYLETAKLKANPEGVGSICLALLYPSSMESGEPETAFELLPLIRIYKNGRIERLVDTDFVPPGTDPLTGVTSKDVTFLPTFGVSARLFLPNLTHSTQRLPVVVYFHGGCFCTQSPFTAKYHNYLNALTAEAKVVAVSVDYRKAPEHPIPTAYEDSWAALQWVISHLDGKGPEIWLNKHVDFKRVFLAGASAGANIAHNLAMVVGDPDCGVNIDLIGVALEHPYFWGSVRIGKEAENPVKARLFDQLWGFICPARPENDDPWVNPVAEGAGRLAGLGSGRVLVCVAEKDVLRDRGRLYFEALGGSGWFGVAEIVETEDEDHLFHLNDSEGQKAKDLIRDLGDFFNRDMPPSLLL
>rna-XM_008448348.2
MPTINLDQIPSFEEHVNGFDQHDVLVEEIEGLIRVYGNGYVERPQIVPCVSNALPPELGVTSWDVVVDKLNNIWARFYIPTQCQEKLPLIVYFHGGGFCVGSAAWSCYHEFLAKLSAKSDCIIISVNYRLAPENPLPAPYEDGLKTLQWLKQVAFVGGKQNWWSRYCDFTKIYLSGDSAGGNIAFNVAARLGGKTTASGAVILKPLVIKGSILIQPFFGGESRTNSEKFLVQPPRSPLTLGVSDTYWRLALPSGTNRDHPWCNPSTKGLFTVEDSRVLPSLICISEMDILKDRNLEFCSALHRAGKLINYVVYEGVGHAFQVLNKSQLSQTRTLEMFDHIKDFLCV
>rna-XM_008451617.2
MAAPVEVDECRGVLRVYSDGSIVRSSNPSFNVPVNDDGSVLWKDLLFDPINDLHLRLYKPADISSPKLSVFFYIHGGGFCIGSRTWPNCQNYCFRLASQLPALVISPDYRLAPENRLPAAIDDGFAALRWLQAQAESDHPDPWLADVADFSRVFISGDSAGGNIAHHLAVGLGLGSPELAPVRVRGYVLLGPFFGGTVRTRSEAEGSKEAFLNLELIDRFWRLSIPIGSDTDHPLVNVFGPTSRNLEAVEMDPIMVVVAGADLLKDRAVEYAEELKKQGKKIDLVEFEGKQHGFFTIDPNSEASNQLMLLINHFVAQHSL
>rna-XM_008454305.2
MATDSNNPELAVELLPYLRLYKNGIVDRLIGTRVTPPGLDSRTGVDSKDIIIVPDTGVSARLYRPTVVDPRRKLPLVVYFHGGAFLVASSAEPIYHNNCLIPLAAEAHTVLLSVNYRLAPEHPLPAAYDDSWAALQWIAAQSQSSADQPGHEPWLEELVDFEKVFLVGDSAGGNISHHMALRAKNSNLGAKIKIVGIALIQPYFWGQEPIGLEIIEHHKRAEVDSWWNFVCPSDRGNDDLLINPFSDGSPAIDGLAGEKVLVIVAGKDILRERGKLYYETLARSEWKGKVEFYETEGEDHAFHMLNPTSEKAKALVKRLAFFLNQD
>rna-XM_008460985.2
MASDDIALNAAPYFIVYKDGRIDRLIGNDIDPPGLDPITGVESKDVDISPDVTVRVYRPKSAAEKISEKLPLLVYFHGGGFCIETAFSPFYHQHISAWVAEANIIAVSVNYRRAPEHQLPIPFEDAWTSMKWIASHSEGKGQDEWLNEIADLNQVYLAGDSAGGNMAHRMALRTVTEGLEGVKIKGLQLIHPHFWGGKLIGEENDWDPNDLFVVENLWFVVSKDIKTLDDPIVNPEHDPDLGRMPAERVGVYVAEKDNLKERGRHYAECLKKSGWGGTVEVVETEGEGHVFHLFNPTCDIAGELVKQLAAFINSGCRG
>rna-XM_008460989.2
MASSTNKNNEVAFDLFPFLRVYSDGRVQRLMITSDFVPADADDPKSPFRSKDVTISTDPAVSARVFIPSSADPNQKLPLLLYVHGGAFCIESAFNLQYHQHVGALAAEANAVAVSVEYRLAPEHPIPACYDDCWDALRWVAAHVNRDGLEPWLNTYVDFNRICLAGDSAGANICHYLAARASSSSEELGGAKVVAMALIHPFFGDGREDRLWKYLCSETRLVRPTKEELAKMGCKRVKIFLAENDFLKFGGRNYDEDLKRSGWNGVVETVEHGGENHVFHLKNPESENAVDLLEKLASFINLD
>rna-XM_008460987.2
MASTEIAHNFSPMIIVYKDGRTERLVGNELIDPSLDPLTGVESKDIIISPETPVSARIYRPKPTAEPHKLPLLIYFHGGGFCIESAFSPTYHNHLNSLVAEANVIAISVEYRRAPEYPLPIAYEDCWTALKWVAAHSAGTGPEEWLNEIADLNRVYFAGDSAGANIANKMAIRVGIEGVAGLNLKGLMLIHPYFWGEKLIGDEEKLKPEDRWFIEKLWYLACPTISGLDDPVVNPEFEPKLGGLAAERVAVYVAEKDSLKDRGWFYSECLKKSGWGGAVEVVETKGQGHVFHLFNPTSDDAVDFVGKLAAFINGGSRD
MTKGKSLVLDVSGWLRLYDDGSVDRTWTGPPEVKFVAESVPPHDEFIDGVAVRDLVIDQNSGLRVRIYLPEVKCGGEVKKLPVVVHFHGGGFCISEADWFMYYHTYTNLAKSAEAICVSVYLRRAPEHRLPAQIEDGFSALKWLQSVALGNEIEPWIVEKADFNRVFLIGDSSGGNLVHSVAARAGETDLAPLKLAGGIPIHPGFVRAKRSKSEIENPQSPFLTLDMVDKFLNLALPVGSSKDHPITCPMGSAAPPLENLNLPPFLLCIAEKDLVIDTEMEYYEAMKAANKEVEILMSKEMGHSFYLNKIALKLDPETAAESDRLFAGIARFIKQH
>rna-XM_008446418.2
MTFPFYLETAKLKANPEGVGSICLALLYPSSMESGEPETAFELLPLIRIYKNGRIERLVDTDFVPPGTDPLTGVTSKDVTFLPTFGVSARLFLPNLTHSTQRLPVVVYFHGGCFCTQSPFTAKYHNYLNALTAEAKVVAVSVDYRKAPEHPIPTAYEDSWAALQWVISHLDGKGPEIWLNKHVDFKRVFLAGASAGANIAHNLAMVVGDPDCGVNIDLIGVALEHPYFWGSVRIGKEAENPVKARLFDQLWGFICPARPENDDPWVNPVAEGAGRLAGLGSGRVLVCVAEKDVLRDRGRLYFEALGGSGWFGVAEIVETEDEDHLFHLNDSEGQKAKDLIRDLGDFFNRDMPPSLLL
>rna-XM_008448348.2
MPTINLDQIPSFEEHVNGFDQHDVLVEEIEGLIRVYGNGYVERPQIVPCVSNALPPELGVTSWDVVVDKLNNIWARFYIPTQCQEKLPLIVYFHGGGFCVGSAAWSCYHEFLAKLSAKSDCIIISVNYRLAPENPLPAPYEDGLKTLQWLKQVAFVGGKQNWWSRYCDFTKIYLSGDSAGGNIAFNVAARLGGKTTASGAVILKPLVIKGSILIQPFFGGESRTNSEKFLVQPPRSPLTLGVSDTYWRLALPSGTNRDHPWCNPSTKGLFTVEDSRVLPSLICISEMDILKDRNLEFCSALHRAGKLINYVVYEGVGHAFQVLNKSQLSQTRTLEMFDHIKDFLCV
>rna-XM_008451617.2
MAAPVEVDECRGVLRVYSDGSIVRSSNPSFNVPVNDDGSVLWKDLLFDPINDLHLRLYKPADISSPKLSVFFYIHGGGFCIGSRTWPNCQNYCFRLASQLPALVISPDYRLAPENRLPAAIDDGFAALRWLQAQAESDHPDPWLADVADFSRVFISGDSAGGNIAHHLAVGLGLGSPELAPVRVRGYVLLGPFFGGTVRTRSEAEGSKEAFLNLELIDRFWRLSIPIGSDTDHPLVNVFGPTSRNLEAVEMDPIMVVVAGADLLKDRAVEYAEELKKQGKKIDLVEFEGKQHGFFTIDPNSEASNQLMLLINHFVAQHSL
>rna-XM_008454305.2
MATDSNNPELAVELLPYLRLYKNGIVDRLIGTRVTPPGLDSRTGVDSKDIIIVPDTGVSARLYRPTVVDPRRKLPLVVYFHGGAFLVASSAEPIYHNNCLIPLAAEAHTVLLSVNYRLAPEHPLPAAYDDSWAALQWIAAQSQSSADQPGHEPWLEELVDFEKVFLVGDSAGGNISHHMALRAKNSNLGAKIKIVGIALIQPYFWGQEPIGLEIIEHHKRAEVDSWWNFVCPSDRGNDDLLINPFSDGSPAIDGLAGEKVLVIVAGKDILRERGKLYYETLARSEWKGKVEFYETEGEDHAFHMLNPTSEKAKALVKRLAFFLNQD
>rna-XM_008460985.2
MASDDIALNAAPYFIVYKDGRIDRLIGNDIDPPGLDPITGVESKDVDISPDVTVRVYRPKSAAEKISEKLPLLVYFHGGGFCIETAFSPFYHQHISAWVAEANIIAVSVNYRRAPEHQLPIPFEDAWTSMKWIASHSEGKGQDEWLNEIADLNQVYLAGDSAGGNMAHRMALRTVTEGLEGVKIKGLQLIHPHFWGGKLIGEENDWDPNDLFVVENLWFVVSKDIKTLDDPIVNPEHDPDLGRMPAERVGVYVAEKDNLKERGRHYAECLKKSGWGGTVEVVETEGEGHVFHLFNPTCDIAGELVKQLAAFINSGCRG
>rna-XM_008460989.2
MASSTNKNNEVAFDLFPFLRVYSDGRVQRLMITSDFVPADADDPKSPFRSKDVTISTDPAVSARVFIPSSADPNQKLPLLLYVHGGAFCIESAFNLQYHQHVGALAAEANAVAVSVEYRLAPEHPIPACYDDCWDALRWVAAHVNRDGLEPWLNTYVDFNRICLAGDSAGANICHYLAARASSSSEELGGAKVVAMALIHPFFGDGREDRLWKYLCSETRLVRPTKEELAKMGCKRVKIFLAENDFLKFGGRNYDEDLKRSGWNGVVETVEHGGENHVFHLKNPESENAVDLLEKLASFINLD
>rna-XM_008460987.2
MASTEIAHNFSPMIIVYKDGRTERLVGNELIDPSLDPLTGVESKDIIISPETPVSARIYRPKPTAEPHKLPLLIYFHGGGFCIESAFSPTYHNHLNSLVAEANVIAISVEYRRAPEYPLPIAYEDCWTALKWVAAHSAGTGPEEWLNEIADLNRVYFAGDSAGANIANKMAIRVGIEGVAGLNLKGLMLIHPYFWGEKLIGDEEKLKPEDRWFIEKLWYLACPTISGLDDPVVNPEFEPKLGGLAAERVAVYVAEKDSLKDRGWFYSECLKKSGWGGAVEVVETKGQGHVFHLFNPTSDDAVDFVGKLAAFINGGSRD
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University