Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Crambe hispanica
Species name
Crambe hispanica is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Crambe_hispanica.CHS.fa
Download
>Crahi.0006s0080.1.v1.1
MVMGTPSSLDEIRKAQRADGPAGILAIGTANPANYVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPDMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDISAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGIRDWNSLFWIAHPGGPAILDEVEKKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSAEEGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>Crahi.0028s0018.1.v1.1
MSNTGMKGVEKQISTRRVANPGKATVLALGKAFPSQVVPQENLVEGFLRDTKCDDPFIKEKLEHLCKTTTVKTRYTVLSREILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLSCIKEWGRQVEDITHIVYVSSSEIRLPGGDLYLSAKLGLKNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKSRPYDLVGAALFGDGAAAVIIGADPLPSESPFMELHYAVQQFLPGTQTVIDGRLSEEGINFKLGRDLPQKIEENIEEFCKKLMGKAGDDSLEFNDMFWTVHPGGPAILNRLETKLKLGREKLECSRRALVDYGNVSSNTILYVMEYMRDELKKQGDAAHEWGLGLAFGPGITFEGLLIRSLAST
>Crahi.0458s0010.1.v1.1
MGSIDATELGSEKKPNSGKATILAIGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILTKYPELAIEGGSTVKQRLDICNDAVTEMAVEASRACIKNWGHSISDITHLVYVSSSEARLPGGDLYLSKGLGLSPETHRVQLYFVGCSGGVAGLRVAKDIAENNPGSRVLLTTSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPVREKPLFELHTAIQNFLPDTEKTIDGRLTDQGINFTLSRELPQIIEDNVESFCKKLIGKAGVACKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEENRKARNMTEGENEWGLILAFGPGVTFEGIVARNLDV
>Crahi.0787s0007.1.v1.1
MVMGMPSSLDEIRKAQRADGPAGILAIGTANPANHVLQVEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPNMCAYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDASVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDEVEKKLGLKAEKMRATRQVLSEYGNMSSACVLFILDEMRRKSAKDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVHV
>Crahi.0887s0010.1.v1.1
MVMVGSTTSSLDEIRKAQRADGPAGILAIGTANPANHVLQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAAKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDISAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDDVEKKLGLKEEKMRATRHVLSEYGNMSSACVLFILDEMRRKSVEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>Crahi.0889s0025.1.v1.1
MLATEREKEIIGQSRRRVANKGKATVLALGKAFPRNIVSQENLVEEYLREIKCEDPSIKEKLQHLCKTTTVKTRYTVMTRETMQKYPELATEGSPTIKQRLEIANEAVVQMAYEASLCCIKEWGRAVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGVSGLRMAKDIAENNPGSRVLLTTSETMVLGFRPPNKARPYDLVGAALFGDGAAALIIGADPTESESPFMELHYALQQFLPGTHGVIDGRLSEEGISFKLGRELPQKIQDNVEDFCKKLVAKAGSASLEFNDLFWAVHPGGPAILNGLETKLELKPDKLECSRRALMDYGNASSNTIFYIMDKVRADLEKKGRGGEEWGLGLAFGPGITFEGFLMRSL
>Crahi.1332s0007.1.v1.1
MVMGALSLDEIRKAQRADGPASILAIGTANPTNQVSQAEYPDYYFRITNSEHMTDLKAKFKRMCDKSMIKKRYMHLTEEFLKDNPNICAFMAASLDVRQDILVDEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLIKLLGLSPSVKRVMMYHQGCHAGGTVLRLAKDIAENNRGARVLIVCSEITVVTFRGPSETHLDSLVGQSLFGDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSEGAIEGHLKEVGLTFHLLKTVPGLISKNIEKSLKEAFKPLGISDWNSLFWIAHPGGPAILDHVEMKLGLKAEKMRATRHVLSEYGNMSSACVFFVLDEMRRKAAEDGAETTGEGLEWGVLFGFGPGLTVETVVLHSVPL
MVMGTPSSLDEIRKAQRADGPAGILAIGTANPANYVIQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPDMCAYMAPSLDARQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDISAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLDEAFKPLGIRDWNSLFWIAHPGGPAILDEVEKKLGLKAEKMRATRHVLSEYGNMSSACVLFILDEMRRKSAEEGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>Crahi.0028s0018.1.v1.1
MSNTGMKGVEKQISTRRVANPGKATVLALGKAFPSQVVPQENLVEGFLRDTKCDDPFIKEKLEHLCKTTTVKTRYTVLSREILDKYPELTTEGSPTIKQRLEIANEAVVEMALEASLSCIKEWGRQVEDITHIVYVSSSEIRLPGGDLYLSAKLGLKNDVNRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKSRPYDLVGAALFGDGAAAVIIGADPLPSESPFMELHYAVQQFLPGTQTVIDGRLSEEGINFKLGRDLPQKIEENIEEFCKKLMGKAGDDSLEFNDMFWTVHPGGPAILNRLETKLKLGREKLECSRRALVDYGNVSSNTILYVMEYMRDELKKQGDAAHEWGLGLAFGPGITFEGLLIRSLAST
>Crahi.0458s0010.1.v1.1
MGSIDATELGSEKKPNSGKATILAIGKAFPQQLVMQEYLVDGYFKTTNCDDPELKQKLTRLCKTTTVKTRYVVMSEEILTKYPELAIEGGSTVKQRLDICNDAVTEMAVEASRACIKNWGHSISDITHLVYVSSSEARLPGGDLYLSKGLGLSPETHRVQLYFVGCSGGVAGLRVAKDIAENNPGSRVLLTTSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIIGSDPDPVREKPLFELHTAIQNFLPDTEKTIDGRLTDQGINFTLSRELPQIIEDNVESFCKKLIGKAGVACKDYNQMFWAVHPGGPAILNRMEKRLNLSPEKLSPSRRALMDYGNASSNSIVYVLEYMLEENRKARNMTEGENEWGLILAFGPGVTFEGIVARNLDV
>Crahi.0787s0007.1.v1.1
MVMGMPSSLDEIRKAQRADGPAGILAIGTANPANHVLQVEYPDYYFRITNSEHMTDLKEKFKRMCDKSMIRKRHMHLTEEFLKENPNMCAYMAPSLDVRQDIVVVEVPKLGKEAAVKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDASVGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDEVEKKLGLKAEKMRATRQVLSEYGNMSSACVLFILDEMRRKSAKDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVHV
>Crahi.0887s0010.1.v1.1
MVMVGSTTSSLDEIRKAQRADGPAGILAIGTANPANHVLQAEYPDYYFRITNSEHMTDLKEKFKRMCDKSTIRKRHMHLTEEFLKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAAAKAIKEWGQPKSKITHVVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFSDGAAALIVGSDPDISAGEKPIFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDDVEKKLGLKEEKMRATRHVLSEYGNMSSACVLFILDEMRRKSVEDGVATTGEGLEWGVLFGFGPGLTVETVVLHSVPV
>Crahi.0889s0025.1.v1.1
MLATEREKEIIGQSRRRVANKGKATVLALGKAFPRNIVSQENLVEEYLREIKCEDPSIKEKLQHLCKTTTVKTRYTVMTRETMQKYPELATEGSPTIKQRLEIANEAVVQMAYEASLCCIKEWGRAVEDITHLVYVSSSEFRLPGGDLYLSAQLGLSNEVQRVMLYFLGCYGGVSGLRMAKDIAENNPGSRVLLTTSETMVLGFRPPNKARPYDLVGAALFGDGAAALIIGADPTESESPFMELHYALQQFLPGTHGVIDGRLSEEGISFKLGRELPQKIQDNVEDFCKKLVAKAGSASLEFNDLFWAVHPGGPAILNGLETKLELKPDKLECSRRALMDYGNASSNTIFYIMDKVRADLEKKGRGGEEWGLGLAFGPGITFEGFLMRSL
>Crahi.1332s0007.1.v1.1
MVMGALSLDEIRKAQRADGPASILAIGTANPTNQVSQAEYPDYYFRITNSEHMTDLKAKFKRMCDKSMIKKRYMHLTEEFLKDNPNICAFMAASLDVRQDILVDEVPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLIKLLGLSPSVKRVMMYHQGCHAGGTVLRLAKDIAENNRGARVLIVCSEITVVTFRGPSETHLDSLVGQSLFGDGAAALIVGSDPDTSVGEKPIFEMVSAAQTILPDSEGAIEGHLKEVGLTFHLLKTVPGLISKNIEKSLKEAFKPLGISDWNSLFWIAHPGGPAILDHVEMKLGLKAEKMRATRHVLSEYGNMSSACVFFVLDEMRRKAAEDGAETTGEGLEWGVLFGFGPGLTVETVVLHSVPL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University