Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Corylus mandshurica
Species name
Corylus mandshurica is a species of eudicot in the family Betulaceae (birch family).
Species info
Gene sequence info
Corylus_mandshurica.CHS.fa
Download
>CmaG0000903.1
MSRINGNGDPDRLYPAAQTRRLPSPGKATILALGKAFPSQLIPQECLVEGYIRDTKCVDSSIKEKLERLCKTTTVKTRYTVMSKEILEKYPELATEGSPTIKQRLEIANPAVLEMAKEASLACIKEWGRPAQDITHIVYVSSSEIRLPGGDLHLSSQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGSNPLTGQESPFMELNYAVQQFLPGTHNVIDGKLSEEGINFKLGRDLPQKIEENIEEFCKKLMLNADLKEFNDLFWAVHPGGPAILNRLQNTLKLTSDKLECSRRALMDYGNVSSNTIFYVMDYMREELKRGREEWGLALAFGPGITFEGILIRSL
>CmaG0001427.1
MGSEGIAHGGSTKVASPGKATILALGKAFPHQLVMQDYLVDGYFRDTNCDDPVLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAIEGSATVKQRLDICNDAVTRMAIEASQACIKNWGRPMSDITHLVYVSSSEARLPGGDLYLAKGLGLSPETQRVMLYFMGCSGAMIIGSDPISGNERPLFELHTAIQHFLPDTEKAIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLIKFVGFPDKDYNKMFWAVHPGGPAILNRIEKRLDLSPEKLNASRRALMDYGNASSNTIVYVLEYMIEEGLMIKKENEGDNEWGLILAFGPGITFEGILARNLTV
>CmaG0018935.1
MVTVEEVRKAQRAEGPATVMAIGTATPPNCVEQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNVCAYMAPSLDARQDMVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAIIVGADPVPDVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGISDWNSLFWIAHPGGPAILDQVESKLGLKSEKLRATRHVLSEFGNMSSACVLFILDDMRRKSAENGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVST
>CmaG0018936.1
MVTVEEVRKAQRAEGPATVMAIGTATPPNCVEQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYIYLTEEILKEHPNICAYMAPSLDARQDMVVVEIPKLGEEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYHQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPGDAHLDNLVGQALFGDGAAAIIVGADPVPDVEKPLFELVSAAQTILPDSDKAIEGHLREVGLTFHLLEDVPGLISKNIEKSLTEAFQLLGISDWNSLFWIAHPGGPAILDQVESKLGLKSEKLRATRHVLSEFGNMSSACVLFILDDMRRKSAENGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVST
>CmaG0015696.1
MASVEEIRKAQRAHGPANILAIGTATPSNCVSQADYPDYYFRITNSEHMTELKEKFRRMCDKSMIKKRYMHLDENILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPTDTHLDSLVGQALFGDGAAAIIVGADPDTSIERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLAEAFAPLGIRDWNSLFWVAHPGGPAILDQVESKLGLKEEKLRATRHVLSEYGNMSSACVLFILDEMRKNSVEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSIPVPVAAIH
>CmaG0015695.1
MASVEEIFNAQRSQGPANVLAIGTANPSNYIYQADFPDYYFRVTKSEHMTDLKRKFKRICEKSMIKKRHMHLTEDILKENPNMCTFAEPSLDARQEIGVVELPKLAKEAALKAIKEWGQPKSKITHLIFSTTLGTSDMPGADYQLTKLLDLKSSVKRIMMYQHGCFGGGTVLRVAKDFAENNKGARVLAVCAEITASCFRGPSESHLDSLVGQSLFGDGAAAVIVGADPDTSVERPLFQLVSATQTLLPDSDGAVQGHMLERGLTFHLLKDLPKIASTNIEKSLVESFSPIGISDWNSLFWIVHPGGPAILDQVEGRLGLEEEKLRASRHVLSEYGNMSTACVLFILDEIRKKSVEEGKATTGGGLDWGVLFGLGPEKAPMSEHTSAMAPPTSQMAHGALTFATTNTILSVQLL
>CmaG0010759.1
MASVEEIRKAQRAHGPANILAIGTATPSNCVSQADYPDYYFRITNSEHMTELKEKFRRMCDKSMIKKRYMHLDENILKENPNICAYMAPSLDARQDLVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLQPSVKRLMMCQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAIIFRGPTESHLDSLVGQALLGDGAAAIIVGADPDKSINERPLFQLVSASQTILPDSDGAIDLHLREVGLTFHLSKDVPGIISKNIEKSLVEAFAPLGIRDWNSLFWVAHPGGPAILDQVELKLGLKEEKLRATRHVLSEYGNIVSACVLFILDEMRKNSVEQGKATTGEGLEWGVLFGFGPGLTVETVVLHSIPVPVAAIH
>CmaG0010757.1
MASVEEIRKAQRAHGPANILAIGTATPSNCVSQADYPDYYFRITNSEHMTELKEKFRRMCDKSMIKKRYMHLDENILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLQPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAIIFRGPTDTHLDSLVGQALFGDGAAAIIVGADPDTSINERPLFQLVSASQTILPDSDGAIDLHLREVGLTFHLSKDVPGIISKNIEKSLVEAFAPLGIRDWNSLFWVAHPGGPAILDQVELKLGLKEEKLRATRHVLSEYGNIVSACVLFILDEMRKNSVEQGKATTGEGLEWGVLFGFGPGLTVETVVLHSIPVPVAAIH
MSRINGNGDPDRLYPAAQTRRLPSPGKATILALGKAFPSQLIPQECLVEGYIRDTKCVDSSIKEKLERLCKTTTVKTRYTVMSKEILEKYPELATEGSPTIKQRLEIANPAVLEMAKEASLACIKEWGRPAQDITHIVYVSSSEIRLPGGDLHLSSQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRILLTTSETTILGFRPPNKERPYDLVGAALFGDGAAAVIIGSNPLTGQESPFMELNYAVQQFLPGTHNVIDGKLSEEGINFKLGRDLPQKIEENIEEFCKKLMLNADLKEFNDLFWAVHPGGPAILNRLQNTLKLTSDKLECSRRALMDYGNVSSNTIFYVMDYMREELKRGREEWGLALAFGPGITFEGILIRSL
>CmaG0001427.1
MGSEGIAHGGSTKVASPGKATILALGKAFPHQLVMQDYLVDGYFRDTNCDDPVLKQKLTRLCKTTTVKTRYVVMSEEILKKYPELAIEGSATVKQRLDICNDAVTRMAIEASQACIKNWGRPMSDITHLVYVSSSEARLPGGDLYLAKGLGLSPETQRVMLYFMGCSGAMIIGSDPISGNERPLFELHTAIQHFLPDTEKAIDGRLTEEGISFKLARELPQIIEDNIEGFCKKLIKFVGFPDKDYNKMFWAVHPGGPAILNRIEKRLDLSPEKLNASRRALMDYGNASSNTIVYVLEYMIEEGLMIKKENEGDNEWGLILAFGPGITFEGILARNLTV
>CmaG0018935.1
MVTVEEVRKAQRAEGPATVMAIGTATPPNCVEQSTYPDYYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKEHPNVCAYMAPSLDARQDMVVVEIPKLGKEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDAHLDSLVGQALFGDGAAAIIVGADPVPDVEKPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLAEAFQPLGISDWNSLFWIAHPGGPAILDQVESKLGLKSEKLRATRHVLSEFGNMSSACVLFILDDMRRKSAENGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVST
>CmaG0018936.1
MVTVEEVRKAQRAEGPATVMAIGTATPPNCVEQSTYPDYYFRITNSEHKTELKEKFKRMCDKSMIKKRYIYLTEEILKEHPNICAYMAPSLDARQDMVVVEIPKLGEEAAVKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYHQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPGDAHLDNLVGQALFGDGAAAIIVGADPVPDVEKPLFELVSAAQTILPDSDKAIEGHLREVGLTFHLLEDVPGLISKNIEKSLTEAFQLLGISDWNSLFWIAHPGGPAILDQVESKLGLKSEKLRATRHVLSEFGNMSSACVLFILDDMRRKSAENGLKTTGEGLEWGVLFGFGPGLTVETVVLHSVST
>CmaG0015696.1
MASVEEIRKAQRAHGPANILAIGTATPSNCVSQADYPDYYFRITNSEHMTELKEKFRRMCDKSMIKKRYMHLDENILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPTDTHLDSLVGQALFGDGAAAIIVGADPDTSIERPLFELVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLAEAFAPLGIRDWNSLFWVAHPGGPAILDQVESKLGLKEEKLRATRHVLSEYGNMSSACVLFILDEMRKNSVEEGKATTGEGLEWGVLFGFGPGLTVETVVLHSIPVPVAAIH
>CmaG0015695.1
MASVEEIFNAQRSQGPANVLAIGTANPSNYIYQADFPDYYFRVTKSEHMTDLKRKFKRICEKSMIKKRHMHLTEDILKENPNMCTFAEPSLDARQEIGVVELPKLAKEAALKAIKEWGQPKSKITHLIFSTTLGTSDMPGADYQLTKLLDLKSSVKRIMMYQHGCFGGGTVLRVAKDFAENNKGARVLAVCAEITASCFRGPSESHLDSLVGQSLFGDGAAAVIVGADPDTSVERPLFQLVSATQTLLPDSDGAVQGHMLERGLTFHLLKDLPKIASTNIEKSLVESFSPIGISDWNSLFWIVHPGGPAILDQVEGRLGLEEEKLRASRHVLSEYGNMSTACVLFILDEIRKKSVEEGKATTGGGLDWGVLFGLGPEKAPMSEHTSAMAPPTSQMAHGALTFATTNTILSVQLL
>CmaG0010759.1
MASVEEIRKAQRAHGPANILAIGTATPSNCVSQADYPDYYFRITNSEHMTELKEKFRRMCDKSMIKKRYMHLDENILKENPNICAYMAPSLDARQDLVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLQPSVKRLMMCQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAIIFRGPTESHLDSLVGQALLGDGAAAIIVGADPDKSINERPLFQLVSASQTILPDSDGAIDLHLREVGLTFHLSKDVPGIISKNIEKSLVEAFAPLGIRDWNSLFWVAHPGGPAILDQVELKLGLKEEKLRATRHVLSEYGNIVSACVLFILDEMRKNSVEQGKATTGEGLEWGVLFGFGPGLTVETVVLHSIPVPVAAIH
>CmaG0010757.1
MASVEEIRKAQRAHGPANILAIGTATPSNCVSQADYPDYYFRITNSEHMTELKEKFRRMCDKSMIKKRYMHLDENILKENPNMCAYMAPSLDARQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLQPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAIIFRGPTDTHLDSLVGQALFGDGAAAIIVGADPDTSINERPLFQLVSASQTILPDSDGAIDLHLREVGLTFHLSKDVPGIISKNIEKSLVEAFAPLGIRDWNSLFWVAHPGGPAILDQVELKLGLKEEKLRATRHVLSEYGNIVSACVLFILDEMRKNSVEQGKATTGEGLEWGVLFGFGPGLTVETVVLHSIPVPVAAIH
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University