Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Aethionema arabicum
Species name
Aethionema arabicum is a species of eudicot in the family Brassicaceae (mustard family).
Species info
Gene sequence info
Aethionema_arabicum.4CL.fa
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>Aa3LG2G213.1
MITATLHDTQIHKPADNASSVAAVVSDDDAPRIFRSKLPDINIPNYLPLHTYCFQKLSTISENPCLIVGSTGKTHTYSETHQICRRVAAGLYKIGIRKGDVIMILLQNSPEFVFSFMGASMIGAVSTTANPFYTSQEISKQLRSSGAKLIITQSQYVEKLRHLSDEISFKIGEDLTVITIEDEPVENCIPFSVLTGETEVELIDSVVVSGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLTPNDVVLCVLPLFHIYSLNSVLFNSLRSGATVVLMHKFEIGALLELIQRHRVTITALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDSLRRRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPFPTKSGSCGTVVRNAELKVIHLDTGLPLTYNQPGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGFVDEDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHHSIADAAVVPQGDEVAGEVPVAFVVRSNGNDITEEDIKDFIAKQVVFYKRLHKVFFVPSIPKSPSGKILRKDLKTKLF
>Aa3LG6G330.1
MEKSGYGRDSIYRSLRPPIVIPKEPNTSLVSFLFRNSSSYPTKPALIDADSGDTFSFSQLKSAVARLAHGFQSLGIGKNDVVLIFAPNSHQFPLCFLAVTAIGGIVTTANPLYTTQEVSKQIKDSNPKIIVSVPQLFDKIKGFELPVVLLGSRETVQGNGSSSRVLSFHDVMELSEPTSDFPLVEVKQSDTAALLYSSGTTGTSKGVELTHGNFITASLMVSKDQEITGEMHSVFLCFIPMFHVFGLAVITYSRLQFGDAVVIMERFDLQAVLKNIEKYRVTHLWAVPPVFLALSKQSTVNNYDLSSLKFMGSGAAPLGKDLMEECVRIIPSALLLQGYGMTETSGVTSVEDSRFGKRNSGSSGSLLSGVEAQIVSVETQKPQPPNKLGEIWVRGPNMMKGYFNNPQATKETIDENGWVHTGDLGYFNEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRVPNSSLTAEQIQNFIAQQVAPYKRLRRVTFIKTVPKSASGKILRRELIQQVRSKM
>Aa3LG8G765.1
MVLQHQTRPEEQSHEFIFRSKLPDISIPSHLPLTDYVFQKHSGDSVTASKNCLIDGITGRVYTYAEVQINSRRIAAGLHRFGIRHRDVVMLLLPNSPEFALSFLAVAYLGAVSTTANPLYTSPEIAKQVKDSAAKMIITKRCYLEKIKNHQNDGVLVVCVDDETDDVSSKSATPPPPPCINFQKLTQSDENALPKQEISPEDTVAMPYSSGTTGLPKGAIITHKGLVTSIAQKVDGENPNINFTGDDVILCFLPMFHIYALDALMLSAMRTGAALLIVPRFEMKLVLDLIQKYKVTVVPVAPPVVLAFVKSTETENYNLSSVRIMLSGAATLKKELEEAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKIPFKAKSGACGTVIRNAEMKIVDTATGVSLPRNQSGEICIRGQQLMKGYLNDPEATAKTIDKDGWLHTGDIGFVDDDDEVFIVDRLKELIKYKGYQVAPAELEALLISHPQIEDAGVVGMKDEVADEIPVAFIVRQAGSQLTEEDVKSYVNKQVVHYKRIKTAIFIEAIPKAASGKILRKELRAKLETESQK
>Aa3LG9G844.1
MEKSGYGRDGIYRSLRPMLILPKDPNTSLVSFLFRNSSSYSSKPALIDSDSGHSFTFSELKSAVARLANGFLRLGIKKNDVVLIFAPNSHQFPLCFLAVAAIGGIVTTVNPLYTENEISKQIKDSNPKIIISVQQLFDKIKGFNLPIVLLGSGESLEVSNTGSNSKILSFNHVMELSEPVSDLPIVDIKQSDTAALLYSSGTTGTSKGVELTHGNFIAACLMVTMDQKLRGEIHSVFLCFLPMFHVFGLVVIVYSQLQMGNALVSMAKFELELLLKNVEKYRVTHLWVVPPVFLALSKHSTEIKYDISSLKFIASGAAPLGKDLMEECGRNIPHVSLLQGYGMTETCGIVSLEDPRLGKRNSGSAGMLGAGIEAQIVSVESGKPQPPNQLGEIWVRGPNMMKGYFNNPQATKETIDKKGWVHTGDLGYFNEDGNIYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRSSKSSITEEEIKTFIAKQVAPFKRLRRVSFINTVPKSAAGKILRRELVQQVRSKI
>Aa3LG10G316.1
MAPQEEVKSAIVEEQKQITTDFIFRSKLPNIEIPNHLPLHEYIFQNISDYASKPCLINGPTGEIYTYSDVHLNSRRIAAGFHKLGINQYDVVMILLPNCPEFVLSFLAASFLGATSTAANPFFTPAEIAKQIKASNSKLIVTESRYADKVKEAQNDGVLIICTDEISTSIPEGCLRFSELTQETESEIEILNSLQISSNDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPIVPPIVLAIAKSPETEKYDLSSIRVVKSGAAPLGKELEDAVNAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKLIDPETGDSLPKNKRGEICIRGDQIMKGYLNNPAATAETIDKDGWLHTGDIGIIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPEITDVAVVAMKEEAAGEVPVAFVVKSKDSKLTEDEVKQFVSKQVVFYKRINKVFFIDSIPKAPSGKILRKDLREKLSNGLIN
>Aa3SC65G3.1
MEDQKQGDEHIFRSLYPSVSIPDKLTLPEFVLQGAEKYAEKVAFVEAVTGKAFTYGDVVRDTRRLAKALTSLGLRKGQAMVVVLPNVAEYGIIVLGIMSAGGVFSGANPTALVSEIKKQVECSGAKGIITDANNYEKVKMLGLPVIVLGEEKIEGAVNWRELLEAGDKAGDNILEKQEILQTDLCALPFSSGTTGMQKGVMLTHRNLIANLCSTLFSVRSEFIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRFDLRIFLNAIITHEVTFAPIVPPIILNLVKNPIVDEFDLSKLKLRTVMTAAAPLAPEILTAFEAKFPNVQAYGLTEHSCITMSHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGRSLPESTPGELCVRSQCVMQGYYKNKEETEKTIDEEGWLHTGDIGYIDEDGDIFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAACVVINPEAKEIEEDILNFVAANVAHYKKVRVVHFVDTIPKSLSGKIMRRLLRDKILKINNFKH
MITATLHDTQIHKPADNASSVAAVVSDDDAPRIFRSKLPDINIPNYLPLHTYCFQKLSTISENPCLIVGSTGKTHTYSETHQICRRVAAGLYKIGIRKGDVIMILLQNSPEFVFSFMGASMIGAVSTTANPFYTSQEISKQLRSSGAKLIITQSQYVEKLRHLSDEISFKIGEDLTVITIEDEPVENCIPFSVLTGETEVELIDSVVVSGDDAAALPFSSGTTGLPKGVVLTHKSLITSVAQQVDGENPNLYLTPNDVVLCVLPLFHIYSLNSVLFNSLRSGATVVLMHKFEIGALLELIQRHRVTITALVPPLVIALAKNPAVNSYDLSSVRLVLSGAAPLGKDLQDSLRRRLPQAVLGQGYGMTEAGPVLSMSLGFAKEPFPTKSGSCGTVVRNAELKVIHLDTGLPLTYNQPGEICIRGQQIMKEYLNDPEATSATIDEEGWLHTGDIGFVDEDDEIFIVDRLKEVIKFKGFQVPPAELESLLINHHSIADAAVVPQGDEVAGEVPVAFVVRSNGNDITEEDIKDFIAKQVVFYKRLHKVFFVPSIPKSPSGKILRKDLKTKLF
>Aa3LG6G330.1
MEKSGYGRDSIYRSLRPPIVIPKEPNTSLVSFLFRNSSSYPTKPALIDADSGDTFSFSQLKSAVARLAHGFQSLGIGKNDVVLIFAPNSHQFPLCFLAVTAIGGIVTTANPLYTTQEVSKQIKDSNPKIIVSVPQLFDKIKGFELPVVLLGSRETVQGNGSSSRVLSFHDVMELSEPTSDFPLVEVKQSDTAALLYSSGTTGTSKGVELTHGNFITASLMVSKDQEITGEMHSVFLCFIPMFHVFGLAVITYSRLQFGDAVVIMERFDLQAVLKNIEKYRVTHLWAVPPVFLALSKQSTVNNYDLSSLKFMGSGAAPLGKDLMEECVRIIPSALLLQGYGMTETSGVTSVEDSRFGKRNSGSSGSLLSGVEAQIVSVETQKPQPPNKLGEIWVRGPNMMKGYFNNPQATKETIDENGWVHTGDLGYFNEDGNLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRVPNSSLTAEQIQNFIAQQVAPYKRLRRVTFIKTVPKSASGKILRRELIQQVRSKM
>Aa3LG8G765.1
MVLQHQTRPEEQSHEFIFRSKLPDISIPSHLPLTDYVFQKHSGDSVTASKNCLIDGITGRVYTYAEVQINSRRIAAGLHRFGIRHRDVVMLLLPNSPEFALSFLAVAYLGAVSTTANPLYTSPEIAKQVKDSAAKMIITKRCYLEKIKNHQNDGVLVVCVDDETDDVSSKSATPPPPPCINFQKLTQSDENALPKQEISPEDTVAMPYSSGTTGLPKGAIITHKGLVTSIAQKVDGENPNINFTGDDVILCFLPMFHIYALDALMLSAMRTGAALLIVPRFEMKLVLDLIQKYKVTVVPVAPPVVLAFVKSTETENYNLSSVRIMLSGAATLKKELEEAVRLKFPNAIFGQGYGMTESGTVAKSLAFAKIPFKAKSGACGTVIRNAEMKIVDTATGVSLPRNQSGEICIRGQQLMKGYLNDPEATAKTIDKDGWLHTGDIGFVDDDDEVFIVDRLKELIKYKGYQVAPAELEALLISHPQIEDAGVVGMKDEVADEIPVAFIVRQAGSQLTEEDVKSYVNKQVVHYKRIKTAIFIEAIPKAASGKILRKELRAKLETESQK
>Aa3LG9G844.1
MEKSGYGRDGIYRSLRPMLILPKDPNTSLVSFLFRNSSSYSSKPALIDSDSGHSFTFSELKSAVARLANGFLRLGIKKNDVVLIFAPNSHQFPLCFLAVAAIGGIVTTVNPLYTENEISKQIKDSNPKIIISVQQLFDKIKGFNLPIVLLGSGESLEVSNTGSNSKILSFNHVMELSEPVSDLPIVDIKQSDTAALLYSSGTTGTSKGVELTHGNFIAACLMVTMDQKLRGEIHSVFLCFLPMFHVFGLVVIVYSQLQMGNALVSMAKFELELLLKNVEKYRVTHLWVVPPVFLALSKHSTEIKYDISSLKFIASGAAPLGKDLMEECGRNIPHVSLLQGYGMTETCGIVSLEDPRLGKRNSGSAGMLGAGIEAQIVSVESGKPQPPNQLGEIWVRGPNMMKGYFNNPQATKETIDKKGWVHTGDLGYFNEDGNIYVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPFPDEEAGEVPIAFVVRSSKSSITEEEIKTFIAKQVAPFKRLRRVSFINTVPKSAAGKILRRELVQQVRSKI
>Aa3LG10G316.1
MAPQEEVKSAIVEEQKQITTDFIFRSKLPNIEIPNHLPLHEYIFQNISDYASKPCLINGPTGEIYTYSDVHLNSRRIAAGFHKLGINQYDVVMILLPNCPEFVLSFLAASFLGATSTAANPFFTPAEIAKQIKASNSKLIVTESRYADKVKEAQNDGVLIICTDEISTSIPEGCLRFSELTQETESEIEILNSLQISSNDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQVDGENPNLYFHSDDVILCVLPMFHIYALNSIMLCGLRVGAAILIMPKFEINLLLELIQRCKVTVAPIVPPIVLAIAKSPETEKYDLSSIRVVKSGAAPLGKELEDAVNAKFPNAKLGQGYGMTEAGPVLAMSLGFAKEPFPVKSGACGTVVRNAEMKLIDPETGDSLPKNKRGEICIRGDQIMKGYLNNPAATAETIDKDGWLHTGDIGIIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPEITDVAVVAMKEEAAGEVPVAFVVKSKDSKLTEDEVKQFVSKQVVFYKRINKVFFIDSIPKAPSGKILRKDLREKLSNGLIN
>Aa3SC65G3.1
MEDQKQGDEHIFRSLYPSVSIPDKLTLPEFVLQGAEKYAEKVAFVEAVTGKAFTYGDVVRDTRRLAKALTSLGLRKGQAMVVVLPNVAEYGIIVLGIMSAGGVFSGANPTALVSEIKKQVECSGAKGIITDANNYEKVKMLGLPVIVLGEEKIEGAVNWRELLEAGDKAGDNILEKQEILQTDLCALPFSSGTTGMQKGVMLTHRNLIANLCSTLFSVRSEFIGQIVTLGLIPFFHIYGIVGICCATMKNKGKVVAMSRFDLRIFLNAIITHEVTFAPIVPPIILNLVKNPIVDEFDLSKLKLRTVMTAAAPLAPEILTAFEAKFPNVQAYGLTEHSCITMSHGDPEKGQGIAKRNSVGFILPNLEVKFIDPDTGRSLPESTPGELCVRSQCVMQGYYKNKEETEKTIDEEGWLHTGDIGYIDEDGDIFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAACVVINPEAKEIEEDILNFVAANVAHYKKVRVVHFVDTIPKSLSGKIMRRLLRDKILKINNFKH
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University