Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Coix lacryma-jobi
Species name
Job's tears (Coix lacryma-jobi) is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Coix_lacryma-jobi.COMT.fa
Download
>Adlay0270_T0090
MGSDSRFVADIVVRECGEVFAGLTSLVDVGGNNGTTARAIAKAFPHVRCSVLELPRVVDAMPAAGATVEFVAGDMMEFIPPADAVLLKVMMFTHNCITGSV
>Adlay0760_T0190
MPPPSTAATNGADVSPTEARLAMMELANMVSVPMALTAVIRLGVPAAIWAGGANAPMSAAELLPAGHPDPSVLERLLRLLASRGVFSEDRTTTTTTTTRRFALTAVGRTLVPAGASGASYADYVLQHHQDALVAAWPRLHEAVLDPRGPEPFARANAGVPAYAYYGKDREANQVMLRAMAGVSEPFMHAFLDGYAAGFRGAATLVDVGGSSGACLEMIMQRVPTIKEGINFDLPDVVADAPPIAGVRHVGGDMFKSIPSGDAIFMKWVLTTWTNDECTAILRNCHAALPDGGKLVACEPVVPEETDTSTRTKALLENDIFVMTTYRTQGRERSEEEFRHLGVTAGFTGFRAIYLDPFYAVLEYTK
>Adlay0776_T0260
MMMDAEQEEEEASFMTAHIVSMTLKAAMELGLIDALAAAPAGTLLTAAELVAQALLPRPAADKAEAAAAVDRMLRFLAAHGVGTCSSTEEGPDGGGGGTALRRYAKGPVCRWLSTTNDNDGQGSLAALAMFGFQQPFLNPWQHMAEAVVSGGVAFEMANGMPAFEYMGKNPHLSALYNQAMSQLTLLACRKMLDRLPAAGEREGDGHGGGPVGDPRGGNNDGDTGRALPVPVRHHLLAQQLERWQGEDGARVREARHGCRLSWAHPLYSCLRGLLGALVHKVDASYLA
>Adlay0828_T0120
MGSTTAADVSSAVADEEACMYAMQLASSSILPMTLKNALELGLLEVLQKEPAGKALAPEEVVARLPEQPANPGAAVMVDRMLRLLASYDVVRCHMEDKDGKYERRYAAAPVCKWLTPNEDGVSMAALALMNQDKVLMESWYYLKEAVLDGGIPFNKAYGMTAFEYHGTDPRFNRVFNEGMKNHSVIITKKLLEFYAGFEEGVSTLVDVGGGIGATLHAITSHHSHIRGINFDLPHVISEAPPFPGVEHVGGDMFKSVPAGDAILMKWILHDWSDEHCAVLLKNCYDALPANGKVIVVECVLPVDTAAVPKAQGVFHVDMIMLAHNPGGKERYEREFRELAKGAGFSGFKATYIYANAWAIEFLK
>Adlay1793_T0060
MASYTSSYSSYAVGNQQDDDDTCMHALKLVGGFVVPFTIKAIIELGIMDRLLTAERAMSAEELTAGLPCPAPAPATAMVDRMLRCLASHGVVRCAAAATELGPDDGKKSSHRRYAAAPVCKWFARGGGVVESVVPFGLMALNKAFMQSWYNIKDAVLEGETPFDNAHGMPLFEYLGANETKNTLFNDAMASHSAIVTKRLVEVFRGFANYSVLVDVGGGKGTTLQMIRGQYENISGVNYDLPHVIAQASPIEGVEHVGGSMFDNIPRGDAIMLKWILHDWGDEDCVKILKNCYTALPANGTMIILEYILPETPEPTPAAERVFDLDLAMMVLFASGKERTEKEFTELAIEAGFSGDHTATYIFSNVRALEFTK
MGSDSRFVADIVVRECGEVFAGLTSLVDVGGNNGTTARAIAKAFPHVRCSVLELPRVVDAMPAAGATVEFVAGDMMEFIPPADAVLLKVMMFTHNCITGSV
>Adlay0760_T0190
MPPPSTAATNGADVSPTEARLAMMELANMVSVPMALTAVIRLGVPAAIWAGGANAPMSAAELLPAGHPDPSVLERLLRLLASRGVFSEDRTTTTTTTTRRFALTAVGRTLVPAGASGASYADYVLQHHQDALVAAWPRLHEAVLDPRGPEPFARANAGVPAYAYYGKDREANQVMLRAMAGVSEPFMHAFLDGYAAGFRGAATLVDVGGSSGACLEMIMQRVPTIKEGINFDLPDVVADAPPIAGVRHVGGDMFKSIPSGDAIFMKWVLTTWTNDECTAILRNCHAALPDGGKLVACEPVVPEETDTSTRTKALLENDIFVMTTYRTQGRERSEEEFRHLGVTAGFTGFRAIYLDPFYAVLEYTK
>Adlay0776_T0260
MMMDAEQEEEEASFMTAHIVSMTLKAAMELGLIDALAAAPAGTLLTAAELVAQALLPRPAADKAEAAAAVDRMLRFLAAHGVGTCSSTEEGPDGGGGGTALRRYAKGPVCRWLSTTNDNDGQGSLAALAMFGFQQPFLNPWQHMAEAVVSGGVAFEMANGMPAFEYMGKNPHLSALYNQAMSQLTLLACRKMLDRLPAAGEREGDGHGGGPVGDPRGGNNDGDTGRALPVPVRHHLLAQQLERWQGEDGARVREARHGCRLSWAHPLYSCLRGLLGALVHKVDASYLA
>Adlay0828_T0120
MGSTTAADVSSAVADEEACMYAMQLASSSILPMTLKNALELGLLEVLQKEPAGKALAPEEVVARLPEQPANPGAAVMVDRMLRLLASYDVVRCHMEDKDGKYERRYAAAPVCKWLTPNEDGVSMAALALMNQDKVLMESWYYLKEAVLDGGIPFNKAYGMTAFEYHGTDPRFNRVFNEGMKNHSVIITKKLLEFYAGFEEGVSTLVDVGGGIGATLHAITSHHSHIRGINFDLPHVISEAPPFPGVEHVGGDMFKSVPAGDAILMKWILHDWSDEHCAVLLKNCYDALPANGKVIVVECVLPVDTAAVPKAQGVFHVDMIMLAHNPGGKERYEREFRELAKGAGFSGFKATYIYANAWAIEFLK
>Adlay1793_T0060
MASYTSSYSSYAVGNQQDDDDTCMHALKLVGGFVVPFTIKAIIELGIMDRLLTAERAMSAEELTAGLPCPAPAPATAMVDRMLRCLASHGVVRCAAAATELGPDDGKKSSHRRYAAAPVCKWFARGGGVVESVVPFGLMALNKAFMQSWYNIKDAVLEGETPFDNAHGMPLFEYLGANETKNTLFNDAMASHSAIVTKRLVEVFRGFANYSVLVDVGGGKGTTLQMIRGQYENISGVNYDLPHVIAQASPIEGVEHVGGSMFDNIPRGDAIMLKWILHDWGDEDCVKILKNCYTALPANGTMIILEYILPETPEPTPAAERVFDLDLAMMVLFASGKERTEKEFTELAIEAGFSGDHTATYIFSNVRALEFTK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University