Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Coix lacryma-jobi
Species name
Job's tears (Coix lacryma-jobi) is a species of monocot in the family Poaceae (grass family).
Species info
Gene sequence info
Coix_lacryma-jobi.CHS.fa
Download
>Adlay0019_T0850
MGTLNAGMGVGNHRSCGLASILGIGKAVPEHVIPQKSFPDFYFEISNSNHMVELKAKFANICEKTMVETRHWYTCLPTCSVAARPSRRTSPLPSPSVNSTPTRAYPGSARAAIADWGRQASDITHLVFCTTASGSIPGADLEVARVLGLPLSTKRVMLYQVGCHGAGVGLRLAKDLAENNRGARVLVVCSEVMALGMRGPSEDDMGNLVGQALFGDAAAAVVVGADPDPGRGSGERALFEMVGSTAGEGLEWGLLFGFGPGLTVETILLRALPNQTTITT
>Adlay0053_T0270
MVEKRHVYMSDEFLRSNPSVTGYRSPSLSLRQQLTDAAVPQLGAEAARKAIGDWGRRASDITHLVFCTTSSGCMPGADFEVVKLLGLPLSTQRFMLYQVGCHGGGLALRLAKDLAENNRGARVLVVCSEVIAMALRGPSETHLGNLVGQAIFGDAACAAIVGVVASGSGGETPLFEMVSASQDILPGTECGLAAKLREEGIVYTLHPDMALHIAGSIEELVESTLARAGLELVVGDRSDREELFWVVHPGGRKIVDAVETALGLGKEKLAASREVMRRHGNTMSSCVLIALEEMRRRSADRGLRTPGEGLEWGLLFGFGPGITVETILLRALPSDVDDDDPTTAK
>Adlay0053_T0280
GVSSFHPSGSRAAILGLGTAVPDNVWPQESFPDYYFEISNSNHMVDLKAKFRGICKCLQTPFSYRVFGLWVEVGYSGSNPDDSKNTGLSPFLF
>Adlay0056_T0160
MIEKRHVSMSEDFLRSNPCITSYKSPSLKLRQELTDATLPQLGAEAARKAIADWGCRRRASDVTHLVFCTSSSGCMPGADFEVVKLLGMPLSTKRFMLYQVGCHGGGLALRLAKDLAENNRGARVLVVCSEVITTTLRGPSETHLGNLVGQAIFGDAACAAIVGAGDAGDGDGDGDGDGDDGETPLFEIVSASQDILPGTELGGVLAKLHEEGIVYTLHPDMPMHISGNIEELVRAALARAGLVVEDPSEELFWVVHPGGRKILDAVESALGLRKEKLEASREVMRRHGNTMSSCVLTTLEEMRRRSADRGLRTPGEGLEWGLLFGFGPGITVETILLRALPNPNPNDDDDPTTT
>Adlay0602_T0060
MGSAPAATTVQEIRRAQRADGPAAVLGIGTANPPTCLAQDEYPDYYFRVTNSEHLTDLKGKLTRICNKSGIRRRYITTGNGEDLLAANPDFTDRTRASLDARVDLASAAVPELAAAAAAKAIADWGRPAADVTHLVFSTYSGARAERRPPPRGPARPPPHRVPHHPQPPRLLRRRPLAKELAENNRGARVLVACSEITLIAFYGPDGGCADNILGQALFGDGAGAVIVGADPDPAAAERPLFEMAFASQTTVPDTEDAISMQINKGGMEYHISSQVPRLVGCNVERCLVDAFRKLGVTAAWNDLFWAIHPGGRAILDHIEGVLGLDDGKLAASRHVLSEFGNMSGTTVIFVLDELRRRRAAAATAKQGREEEAPEDGFWTGNHNRDHGAPYT
>Adlay0913_T0150
ALVGDWLLELALSPETQDEYPDYYFQVTNSEHLTDLKGKLIRICNKSGIRRRYIHLSEDLLAADPDFTDRTLPSLDARHLLRRARAQRDRRLAALLGLRPTVSRTILNLHGCYGGGRSLQLAKELAENNRGARVLVACSEITLIAFYGPKGGCADNILGQALFGDGVDPDPAAAAERPLFEMAFASQTTIPDTKDAIPMQIMSPEVSGGGAGSSGGAGVGQRATGERGIGGPGSWGLQTRF
>Adlay2271_T0010
MAGATATVTVEEVRKAQRASGPATVLAIGTATPANCVYQADYPDYYFRITKSDHLTDLKEKFKRMCDKSMIRKRYMHLTEEFLAENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAVVVGADPDERVERPLFQLVSAAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNVERALEDAFAPLGIHDWNSVFWVAHPGGPAILDQVEAKVGLDKARMRATRHVLSEYGNMSSACVLFILDEMRKRSAEEGHATTGEGFDWGVLFGFGPGLTVETVVLHSVPITNGAAITA
>Adlay2412_T0060
MALWLRGPSEAHMGNLVGQALFGDAAGAVVVGADPDPGERALFEMVSASQDVIAGTEEAVVSRLYEEGIVYTLLRDVALHVSSNVERLAKAALEKKKAMAISGGGGEDDDELFWVVHPGGREILDRVESRLGLGKEKLAASREVMRQYGNTLSSSVLLVLDEMRRRSAQQGMRTAGEGLEWGVLFGFGPGLTVETILLRALPLPLSLTNNQNTTA
MGTLNAGMGVGNHRSCGLASILGIGKAVPEHVIPQKSFPDFYFEISNSNHMVELKAKFANICEKTMVETRHWYTCLPTCSVAARPSRRTSPLPSPSVNSTPTRAYPGSARAAIADWGRQASDITHLVFCTTASGSIPGADLEVARVLGLPLSTKRVMLYQVGCHGAGVGLRLAKDLAENNRGARVLVVCSEVMALGMRGPSEDDMGNLVGQALFGDAAAAVVVGADPDPGRGSGERALFEMVGSTAGEGLEWGLLFGFGPGLTVETILLRALPNQTTITT
>Adlay0053_T0270
MVEKRHVYMSDEFLRSNPSVTGYRSPSLSLRQQLTDAAVPQLGAEAARKAIGDWGRRASDITHLVFCTTSSGCMPGADFEVVKLLGLPLSTQRFMLYQVGCHGGGLALRLAKDLAENNRGARVLVVCSEVIAMALRGPSETHLGNLVGQAIFGDAACAAIVGVVASGSGGETPLFEMVSASQDILPGTECGLAAKLREEGIVYTLHPDMALHIAGSIEELVESTLARAGLELVVGDRSDREELFWVVHPGGRKIVDAVETALGLGKEKLAASREVMRRHGNTMSSCVLIALEEMRRRSADRGLRTPGEGLEWGLLFGFGPGITVETILLRALPSDVDDDDPTTAK
>Adlay0053_T0280
GVSSFHPSGSRAAILGLGTAVPDNVWPQESFPDYYFEISNSNHMVDLKAKFRGICKCLQTPFSYRVFGLWVEVGYSGSNPDDSKNTGLSPFLF
>Adlay0056_T0160
MIEKRHVSMSEDFLRSNPCITSYKSPSLKLRQELTDATLPQLGAEAARKAIADWGCRRRASDVTHLVFCTSSSGCMPGADFEVVKLLGMPLSTKRFMLYQVGCHGGGLALRLAKDLAENNRGARVLVVCSEVITTTLRGPSETHLGNLVGQAIFGDAACAAIVGAGDAGDGDGDGDGDGDDGETPLFEIVSASQDILPGTELGGVLAKLHEEGIVYTLHPDMPMHISGNIEELVRAALARAGLVVEDPSEELFWVVHPGGRKILDAVESALGLRKEKLEASREVMRRHGNTMSSCVLTTLEEMRRRSADRGLRTPGEGLEWGLLFGFGPGITVETILLRALPNPNPNDDDDPTTT
>Adlay0602_T0060
MGSAPAATTVQEIRRAQRADGPAAVLGIGTANPPTCLAQDEYPDYYFRVTNSEHLTDLKGKLTRICNKSGIRRRYITTGNGEDLLAANPDFTDRTRASLDARVDLASAAVPELAAAAAAKAIADWGRPAADVTHLVFSTYSGARAERRPPPRGPARPPPHRVPHHPQPPRLLRRRPLAKELAENNRGARVLVACSEITLIAFYGPDGGCADNILGQALFGDGAGAVIVGADPDPAAAERPLFEMAFASQTTVPDTEDAISMQINKGGMEYHISSQVPRLVGCNVERCLVDAFRKLGVTAAWNDLFWAIHPGGRAILDHIEGVLGLDDGKLAASRHVLSEFGNMSGTTVIFVLDELRRRRAAAATAKQGREEEAPEDGFWTGNHNRDHGAPYT
>Adlay0913_T0150
ALVGDWLLELALSPETQDEYPDYYFQVTNSEHLTDLKGKLIRICNKSGIRRRYIHLSEDLLAADPDFTDRTLPSLDARHLLRRARAQRDRRLAALLGLRPTVSRTILNLHGCYGGGRSLQLAKELAENNRGARVLVACSEITLIAFYGPKGGCADNILGQALFGDGVDPDPAAAAERPLFEMAFASQTTIPDTKDAIPMQIMSPEVSGGGAGSSGGAGVGQRATGERGIGGPGSWGLQTRF
>Adlay2271_T0010
MAGATATVTVEEVRKAQRASGPATVLAIGTATPANCVYQADYPDYYFRITKSDHLTDLKEKFKRMCDKSMIRKRYMHLTEEFLAENPNMCAYMAPSLDARQDIVVVEVPKLGKAAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKMLGLRPSVNRLMMYQQGCFAGGTVLRVAKDLAENNRGARVLVVCSEITAVTFRGPSESHLDSLVGQALFGDGAAAVVVGADPDERVERPLFQLVSAAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNVERALEDAFAPLGIHDWNSVFWVAHPGGPAILDQVEAKVGLDKARMRATRHVLSEYGNMSSACVLFILDEMRKRSAEEGHATTGEGFDWGVLFGFGPGLTVETVVLHSVPITNGAAITA
>Adlay2412_T0060
MALWLRGPSEAHMGNLVGQALFGDAAGAVVVGADPDPGERALFEMVSASQDVIAGTEEAVVSRLYEEGIVYTLLRDVALHVSSNVERLAKAALEKKKAMAISGGGGEDDDELFWVVHPGGREILDRVESRLGLGKEKLAASREVMRQYGNTLSSSVLLVLDEMRRRSAQQGMRTAGEGLEWGVLFGFGPGLTVETILLRALPLPLSLTNNQNTTA
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University