Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Coffea canephora
Species name
Robusta coffee (Coffea canephora) is a species of eudicot in the family Rubiaceae (madder family).
Species info
Gene sequence info
Coffea_canephora.COMT.fa
Download
>gene-GSCOC_T00015815001
MTKTLLDFHPMYELGNSLLEGGIPFNRVHGMHAFDYPSRDPRYNELFNKGMVGPTAITMKKLLQQYKGFEHLQTLVDVGGGLGITLHKIISKYPSIRGINFDLPHVIENAPSYLGVEHIGGDMFESVPGGDAIFMKMILHDWSDDHCLKLLKNCFKALPDHGKVIVVDLVLPVKPDTSAFVKGIFQTDALMMTQNPGGKERSESDVRALAIRAGFKDIKLECCVGSLGVLELYK
>gene-GSCOC_T00015814001
MLRLLSSYSLLTCDVVEVAGERAGGETDVGYVRVYGLSPVAEYFVPDEEGNSVAPAMELLQDKVLIDSWRGWTGFKKEEGEGDLNPEPLIPWCLNLSC
>gene-GSCOC_T00015810001
MESSVKTQLKSSSSSGENGKEGEKQNHFSYAMQLVSSASLTMVLYNAVKLNLFEIIAKAGPGAKLSPSEIASQLPVTNNPDAASMLDRMLRLLSSYSLFTCDVVEVAVDGGGGGETNVGYERVYGLSPVAEYFVPDEEGNSVAPLVELLQDKVLIDSWYELGNAVLEGGIPFNRVHGVHAFDFPSRDPKYNELFNKGMVGPTAIMMKELLQQYKGFEHLQTLVDVGGGLGITLHKIISKYPSIRGINFDLPHVIENAPSYPGVEHIDGDMFESVPGGDAIFMKMILHDWSDDHCLKLLKNCFKALPGHGKVIVVDLILPVKPDTSAFVKGIFQADALMMTQNPGGKERSESDVRALAIRAGFKDVKLQCLVGNVGVLELYK
>gene-GSCOC_T00019870001
MAEEEACLFAMSLASASVLPMVLKSAIELDLLELIAKAGPGAYVSPSELAAQLPTHNPEAPIMLDRILRLLATYSVLDCKLNNLADGGVERLYGLAPVCKFLTKNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTITMKKILEVYRGFEGLKTVVDVGGGTGATLNMIISKYPTIKGINFELPHVVEDAPSHSGVEHVGGDMFVSVPKGDAIFMKWICHDWSDDHCRKLLKNCYQALPDNGKVILAECVLPEAPDTSLATQNVVHVDVVMLAHNPGGKERTEKEFEALAKGAGFKEFRKVCSAVNTWIMELCK
>gene-GSCOC_T00042764001
MHLITSASLSMVLYTAVKLKLFEIIAKAGPGAKLSPSKIASVLLKTKNPDASSMLDRMLQLLSSHSLLSCDVVEVADGGAGGKNDVGYERVYGLSPVGEYFVPDEEGNSLAPTLELVQDKVLMDCWYELGNAVLEGGIPFSRVHGTHVFDYCSRDPRFTDLFNKGMVGPTVITMKELLHQYKGFENLQTLVDVGGGLGMSLHKIV
>rna-GSCOC_T00014504001
MAEEEACLFAMHLASASVLPMVLKLAIELDLLELIATAWIAVLAFAGTAKNLTLGNLLVALEE
>gene-GSCOC_T00004357001
MAGDSSLIDLTCLVMTQCMSVFEDLTSLVDVEGGTSEFTKAIAQNFPNLECLVCDLPHVVANQHRTENLDFVAGNMLEMVPPGDAILLKLIWQELALTKMAISILHDWSDDGCVKILKNCNNAIPERSKGGKVNMDMAMLVLHGAKETTEKEWAKLFQDAGFSNYKVFPVLGLRCLVEVYPD
>rna-GSCOC_T00018215001
MAEEEACLFAMHLASASVLPMVLKLAIELDLLELIATAWIAVLAFAGTAKNLTLGNLLVALEE
>gene-GSCOC_T00018212001
MDSLAETTKNHGVVLKEEDEEEEHFSYAMQLVTSAAQPMVLLAAIRLDVFEIIARAGPGAQLSPSEIAANVSSENPNAAAMLDRMLRLLASYSVLTCSVATDVDGDHDIQTPTRVYGLAPVAKFFVQNKTKGGGSLGSVLGLLQDKVFIDSWYELEDAVRKGGDPFHRAHGTHAFEFLGSDPRFNEVFNKAMVHHTAIVINRMLERYKGFEHLKTLVDVGGGLGMNLNIITTKYPSLKGNNFDLPHVIQHAPAYPGVEHVGGDMFESVPQGDAIFMKWILHDWDDGHCLKLLKNCYKALPDNGKVIAVDAILPVVPDDSARDKATCLADLVVVTQYRGGIERYETELLALATAAGYMIELGVIGYC
>gene-GSCOC_T00007228001
MVLNAAVKLDVLEIIAKAGPGGKLSPSEIVSQMPTKNPDAPDFLDRMLRLLAGYSVLTCSVVDGGAGAHHERRYGLAPVAKYFIKHQYGATLRQLSVYLQNKLLMDSWYQLEGSVLEGGNAFKRTHGCELYTYMAKDPTYNEAFNKAMSCHTKVVLEKALECYKGFENLKTLVDVGGALGQAIHMITSKYPDIKGINFDLPHVIELAPPYPGIEHKGGDMFESVPEADAIFMKWILHNWDDEHCVKLLRNCYKALPNDGKVIVVDAIVPVNPENSDAAAKSNMQIDLFMMAVCSPGAKGRSELEFRALATEAGFRGIRVDCRLFDLWVLEFYK
>gene-GSCOC_T00030420001
MGVSKCPESEGGINFDLPFVSKNAPPCAGVEHVEGDVFQCVPRGEAILLKVSAKNTLIYSTSSDRHTQKGKKIYNLPNN
>gene-GSCOC_T00004324001
MLDRVLWLLASYSVLTCSVAEADASISSQRRVYGLVSVAKYFMQNRTYGAGRGVSLGPLLAVLQDKVFIDRYVITAKYPSLKGINFDLPRVIQHALVYPGAEHVGGDMFGAAVYALV
>gene-GSCOC_T00012514001
MDSLSKATNNVVVEAGLDEQEEQHFSYAMQLVTSVSLPMVLLAVIRLDVLEVIAEAGPGAQLSPWDIAAQVCPKNPDAAAMLDRMLRLLASFSVLTCSVAEADARISSQRRVYGLTPVAKYFVQNKTYGAGGGVSLGPLLALVQDKVFIDSWYQLEDAVREGGVPFDRVHGMHAFEYPARDPRFNEVFNKAMVNRTTIAINRMVERYKGFEHLKTLVDVGGGLGVTLSVITAKYPSLKGINFDLPHVIQHAPVYPGVEHVGGDMFDSVPQGDAIFLRLILHDWDDGRCLKLLMNCFKALPKDGKVIVVDAIVPVVPGTSACIKAICQSDLIMMAQNPGGKERSEAEFLDLATAAGFRGIRVEFFVCNAWVMEFYK
>gene-GSCOC_T00012515001
MLQLLASYSVLTCSVAEADASISSQRRVYGLAPVAKYFVQNKTYAAGGGGVSLGPLLALLQDKVFIDSWYQLEDAVREGGVPFDRVHGVHAFEYPARDPRFNEVFNKAMINPTTIAINRIVQRYKGFEHLKTLVDVGGGLGVTLGVITAKYPSLKGINFDLPHVIQHALVYPGVEHVGGDMFESVPQGDAIFLRSILHDWDDGRCLKLLKNCFKALPKDGKVIVVDAIVPVVPDTSACIKAICQSDLFMMAQNPGGKERSEAEFLDLATAAGFRGIRVECFVCNAWVMEFYK
>gene-GSCOC_T00012516001
MDSSSRATDNVVVEAGLDEQEEQHFSYAMQLVTSVSLPMVLLAAIRLDVLEVIAQAGPGAQLSPWDIAAQVGPKNPDAAAMLDRMLQLLASYSVLTCSVAEADASISSQRRVYGLAPVAKYFVQNKTYAAGGGGVSLGPLLALFQDKVFIDSWYQLEDAVREGGVPFDRAYGVRAFEYPGRDPRFNEVFNKAMINHATIAINRIVERYKGFEHLKTLVDVGGGLGVTLSVITTKYPSLKGINFDLPHVIQHAPVYPGVEHVGGDMFESVPQGDAIFMKWILHFWDDGRCLKLLKNCFKALPDHGKVIVVDPILPVVPDTSAGIKATCQSDLITMTQNPGGKERSEAEFLDLATAAGFRGIMVVCFVCNVWVMEFYK
>gene-GSCOC_T00005982001
MDSLAETTKNQVVLKEEEEEEEEHFSYAMQLVTSAGLPMMLLAAIRLNVFEIIARAGPGAQLSPSEIAANVSSENPNAAAMLDRMLRLLASYSVLTCSVATDVDGDHAIQTPTRVYGLAPVGQVLCTEQNKGRRFTKLLLALLQDKVFIDEDAVREGGDPFHRAHGTHAFEFLGSDPRFNEVFNKTMIHHTAIVINRMLERYKGFEHLKTLVDVGGGLGMNLNIITTKYPSLKVIILICHMLYNMHQPILV
>gene-GSCOC_T00003705001
MFSIQKSCELSKERLDAFPEAKNHFKEDEEEEHFSYAMQLVTSAAQPMVLLAAIRLDVFEIIARAGPGAQLSPSEIAANVSSENPNAAAMLDRMLRLLASYSVLTCSVATDVDGDHEIQTPTRVYGLAPVAKFFVQNKTKGGGSLSSLLALLQDKVFIDSWYQLEDAVRKGGDPFHRAHG
>gene-GSCOC_T00008849001
MDSLAETTKNHGVALKEEEEEEEHFSYAMQLVTSAAQPMVLLAAIRLDVFEIIARAGPGAQLSPSEIAANVSSENPNAAAMLDRMLRLLASYSVLTCSVATDVDGDHDIQTPTRVYGLAPVAKFFVQNKTKGGGSLGSVLGLLQDKVFIDSWYQLEDAVRKGGDPFHRAHGTHAFEFLGSDPRFNEVFNKAMIHHTAIVINRMLERYKGFEHLKTLVDVGGGLGMNLNIITTKYPSLKGINFDLPHVIQHAPAYPGVEHVGGDMFESVPQGDAIFMKWILHDWDDGHCLKLLKNCYKALPDNGKVIAVDAILPVVPDDSARDKATCQADLVVVTQYRGGIERYETEFLALATAAGFKGISVKCFVCNLWVMEFYK
>gene-GSCOC_T00000228001
MACDSQLVGSILIRDCKDVFSGLNSLVDVGGGTGTLAKEIADAFLDLNCIVTDLPHVVDGLVANNKSLAFVGGDMFVAIPPADDVIMKWILHDWNDEECVQMLRKCKEAIPSKENGGKLNFSVIR
MTKTLLDFHPMYELGNSLLEGGIPFNRVHGMHAFDYPSRDPRYNELFNKGMVGPTAITMKKLLQQYKGFEHLQTLVDVGGGLGITLHKIISKYPSIRGINFDLPHVIENAPSYLGVEHIGGDMFESVPGGDAIFMKMILHDWSDDHCLKLLKNCFKALPDHGKVIVVDLVLPVKPDTSAFVKGIFQTDALMMTQNPGGKERSESDVRALAIRAGFKDIKLECCVGSLGVLELYK
>gene-GSCOC_T00015814001
MLRLLSSYSLLTCDVVEVAGERAGGETDVGYVRVYGLSPVAEYFVPDEEGNSVAPAMELLQDKVLIDSWRGWTGFKKEEGEGDLNPEPLIPWCLNLSC
>gene-GSCOC_T00015810001
MESSVKTQLKSSSSSGENGKEGEKQNHFSYAMQLVSSASLTMVLYNAVKLNLFEIIAKAGPGAKLSPSEIASQLPVTNNPDAASMLDRMLRLLSSYSLFTCDVVEVAVDGGGGGETNVGYERVYGLSPVAEYFVPDEEGNSVAPLVELLQDKVLIDSWYELGNAVLEGGIPFNRVHGVHAFDFPSRDPKYNELFNKGMVGPTAIMMKELLQQYKGFEHLQTLVDVGGGLGITLHKIISKYPSIRGINFDLPHVIENAPSYPGVEHIDGDMFESVPGGDAIFMKMILHDWSDDHCLKLLKNCFKALPGHGKVIVVDLILPVKPDTSAFVKGIFQADALMMTQNPGGKERSESDVRALAIRAGFKDVKLQCLVGNVGVLELYK
>gene-GSCOC_T00019870001
MAEEEACLFAMSLASASVLPMVLKSAIELDLLELIAKAGPGAYVSPSELAAQLPTHNPEAPIMLDRILRLLATYSVLDCKLNNLADGGVERLYGLAPVCKFLTKNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDPRFNKVFNQGMSNHSTITMKKILEVYRGFEGLKTVVDVGGGTGATLNMIISKYPTIKGINFELPHVVEDAPSHSGVEHVGGDMFVSVPKGDAIFMKWICHDWSDDHCRKLLKNCYQALPDNGKVILAECVLPEAPDTSLATQNVVHVDVVMLAHNPGGKERTEKEFEALAKGAGFKEFRKVCSAVNTWIMELCK
>gene-GSCOC_T00042764001
MHLITSASLSMVLYTAVKLKLFEIIAKAGPGAKLSPSKIASVLLKTKNPDASSMLDRMLQLLSSHSLLSCDVVEVADGGAGGKNDVGYERVYGLSPVGEYFVPDEEGNSLAPTLELVQDKVLMDCWYELGNAVLEGGIPFSRVHGTHVFDYCSRDPRFTDLFNKGMVGPTVITMKELLHQYKGFENLQTLVDVGGGLGMSLHKIV
>rna-GSCOC_T00014504001
MAEEEACLFAMHLASASVLPMVLKLAIELDLLELIATAWIAVLAFAGTAKNLTLGNLLVALEE
>gene-GSCOC_T00004357001
MAGDSSLIDLTCLVMTQCMSVFEDLTSLVDVEGGTSEFTKAIAQNFPNLECLVCDLPHVVANQHRTENLDFVAGNMLEMVPPGDAILLKLIWQELALTKMAISILHDWSDDGCVKILKNCNNAIPERSKGGKVNMDMAMLVLHGAKETTEKEWAKLFQDAGFSNYKVFPVLGLRCLVEVYPD
>rna-GSCOC_T00018215001
MAEEEACLFAMHLASASVLPMVLKLAIELDLLELIATAWIAVLAFAGTAKNLTLGNLLVALEE
>gene-GSCOC_T00018212001
MDSLAETTKNHGVVLKEEDEEEEHFSYAMQLVTSAAQPMVLLAAIRLDVFEIIARAGPGAQLSPSEIAANVSSENPNAAAMLDRMLRLLASYSVLTCSVATDVDGDHDIQTPTRVYGLAPVAKFFVQNKTKGGGSLGSVLGLLQDKVFIDSWYELEDAVRKGGDPFHRAHGTHAFEFLGSDPRFNEVFNKAMVHHTAIVINRMLERYKGFEHLKTLVDVGGGLGMNLNIITTKYPSLKGNNFDLPHVIQHAPAYPGVEHVGGDMFESVPQGDAIFMKWILHDWDDGHCLKLLKNCYKALPDNGKVIAVDAILPVVPDDSARDKATCLADLVVVTQYRGGIERYETELLALATAAGYMIELGVIGYC
>gene-GSCOC_T00007228001
MVLNAAVKLDVLEIIAKAGPGGKLSPSEIVSQMPTKNPDAPDFLDRMLRLLAGYSVLTCSVVDGGAGAHHERRYGLAPVAKYFIKHQYGATLRQLSVYLQNKLLMDSWYQLEGSVLEGGNAFKRTHGCELYTYMAKDPTYNEAFNKAMSCHTKVVLEKALECYKGFENLKTLVDVGGALGQAIHMITSKYPDIKGINFDLPHVIELAPPYPGIEHKGGDMFESVPEADAIFMKWILHNWDDEHCVKLLRNCYKALPNDGKVIVVDAIVPVNPENSDAAAKSNMQIDLFMMAVCSPGAKGRSELEFRALATEAGFRGIRVDCRLFDLWVLEFYK
>gene-GSCOC_T00030420001
MGVSKCPESEGGINFDLPFVSKNAPPCAGVEHVEGDVFQCVPRGEAILLKVSAKNTLIYSTSSDRHTQKGKKIYNLPNN
>gene-GSCOC_T00004324001
MLDRVLWLLASYSVLTCSVAEADASISSQRRVYGLVSVAKYFMQNRTYGAGRGVSLGPLLAVLQDKVFIDRYVITAKYPSLKGINFDLPRVIQHALVYPGAEHVGGDMFGAAVYALV
>gene-GSCOC_T00012514001
MDSLSKATNNVVVEAGLDEQEEQHFSYAMQLVTSVSLPMVLLAVIRLDVLEVIAEAGPGAQLSPWDIAAQVCPKNPDAAAMLDRMLRLLASFSVLTCSVAEADARISSQRRVYGLTPVAKYFVQNKTYGAGGGVSLGPLLALVQDKVFIDSWYQLEDAVREGGVPFDRVHGMHAFEYPARDPRFNEVFNKAMVNRTTIAINRMVERYKGFEHLKTLVDVGGGLGVTLSVITAKYPSLKGINFDLPHVIQHAPVYPGVEHVGGDMFDSVPQGDAIFLRLILHDWDDGRCLKLLMNCFKALPKDGKVIVVDAIVPVVPGTSACIKAICQSDLIMMAQNPGGKERSEAEFLDLATAAGFRGIRVEFFVCNAWVMEFYK
>gene-GSCOC_T00012515001
MLQLLASYSVLTCSVAEADASISSQRRVYGLAPVAKYFVQNKTYAAGGGGVSLGPLLALLQDKVFIDSWYQLEDAVREGGVPFDRVHGVHAFEYPARDPRFNEVFNKAMINPTTIAINRIVQRYKGFEHLKTLVDVGGGLGVTLGVITAKYPSLKGINFDLPHVIQHALVYPGVEHVGGDMFESVPQGDAIFLRSILHDWDDGRCLKLLKNCFKALPKDGKVIVVDAIVPVVPDTSACIKAICQSDLFMMAQNPGGKERSEAEFLDLATAAGFRGIRVECFVCNAWVMEFYK
>gene-GSCOC_T00012516001
MDSSSRATDNVVVEAGLDEQEEQHFSYAMQLVTSVSLPMVLLAAIRLDVLEVIAQAGPGAQLSPWDIAAQVGPKNPDAAAMLDRMLQLLASYSVLTCSVAEADASISSQRRVYGLAPVAKYFVQNKTYAAGGGGVSLGPLLALFQDKVFIDSWYQLEDAVREGGVPFDRAYGVRAFEYPGRDPRFNEVFNKAMINHATIAINRIVERYKGFEHLKTLVDVGGGLGVTLSVITTKYPSLKGINFDLPHVIQHAPVYPGVEHVGGDMFESVPQGDAIFMKWILHFWDDGRCLKLLKNCFKALPDHGKVIVVDPILPVVPDTSAGIKATCQSDLITMTQNPGGKERSEAEFLDLATAAGFRGIMVVCFVCNVWVMEFYK
>gene-GSCOC_T00005982001
MDSLAETTKNQVVLKEEEEEEEEHFSYAMQLVTSAGLPMMLLAAIRLNVFEIIARAGPGAQLSPSEIAANVSSENPNAAAMLDRMLRLLASYSVLTCSVATDVDGDHAIQTPTRVYGLAPVGQVLCTEQNKGRRFTKLLLALLQDKVFIDEDAVREGGDPFHRAHGTHAFEFLGSDPRFNEVFNKTMIHHTAIVINRMLERYKGFEHLKTLVDVGGGLGMNLNIITTKYPSLKVIILICHMLYNMHQPILV
>gene-GSCOC_T00003705001
MFSIQKSCELSKERLDAFPEAKNHFKEDEEEEHFSYAMQLVTSAAQPMVLLAAIRLDVFEIIARAGPGAQLSPSEIAANVSSENPNAAAMLDRMLRLLASYSVLTCSVATDVDGDHEIQTPTRVYGLAPVAKFFVQNKTKGGGSLSSLLALLQDKVFIDSWYQLEDAVRKGGDPFHRAHG
>gene-GSCOC_T00008849001
MDSLAETTKNHGVALKEEEEEEEHFSYAMQLVTSAAQPMVLLAAIRLDVFEIIARAGPGAQLSPSEIAANVSSENPNAAAMLDRMLRLLASYSVLTCSVATDVDGDHDIQTPTRVYGLAPVAKFFVQNKTKGGGSLGSVLGLLQDKVFIDSWYQLEDAVRKGGDPFHRAHGTHAFEFLGSDPRFNEVFNKAMIHHTAIVINRMLERYKGFEHLKTLVDVGGGLGMNLNIITTKYPSLKGINFDLPHVIQHAPAYPGVEHVGGDMFESVPQGDAIFMKWILHDWDDGHCLKLLKNCYKALPDNGKVIAVDAILPVVPDDSARDKATCQADLVVVTQYRGGIERYETEFLALATAAGFKGISVKCFVCNLWVMEFYK
>gene-GSCOC_T00000228001
MACDSQLVGSILIRDCKDVFSGLNSLVDVGGGTGTLAKEIADAFLDLNCIVTDLPHVVDGLVANNKSLAFVGGDMFVAIPPADDVIMKWILHDWNDEECVQMLRKCKEAIPSKENGGKLNFSVIR
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University