Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Aeschynomene evenia
Species name
Aeschynomene evenia is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Aeschynomene_evenia.HIDH.fa
Download
>Ae03g02240.1
MDSASGEVAVDYSPFIKIYKDGRIQRLIGCDVVPPSHDPTTNVESKDVVISETDDISARIFIPKHHDHQNQKLPVLVYFHGGGFCIETPFSPHYHNFLNAVVSGARVIGVSVHYRRAPEHPVPIAYEDSWASLKWVASHSDGKGPDEWLNRYADLGNVFFGGDSAGANIAHHMGIRVGSEGIPGMKVQGVFLVHSYFWGEERIGSESDGSKAQHLPLVGNLWRFVCPTSAGSDDPMINPSKDPNLGKMGCERVLVFVAENDVLKDRGWHYKESIEKSGWGGAVELVETKGEGHVFHLFNPSGHNSLSLLNRVVSFIKQT
>Ae03g02210.1
MDSAAGKEVLREFPFLFRLYKDGTVERFMGTDTTPPGTDPLTHVHSKDITINPFTGVAARIYLPPTSPSAAQKLPLLIYIHGGAFCICTPYNSTYHRHINNIAAEANALVLSVHYRLAPSTPSAAYDDSWEAIQWTATHAAASGGGLEPWLNDYADFNRVFLGGDSAGANIAHNMAVRGTTEGFGGMNLEGVVLIHPYFGNEKKDELIEFLYPSYGGLDDPKIHPDKDPTVSGLGCERMLVLVAEKDFLRERGRRYYETVKKSGWGGVVEMVETEGEEHVFHLLNPTKDKSLHLVKQIASFINQHTC
>Ae03g02230.1
MATAQAKDITHEFRFFRVYSDGTVQLHRPPTQTIPPFDDLSTGLRSKDAVISTDPPVSVRLFLPRITDPTQKLPVLFYIHGGGFCMQSAFSPTYHNLVATLAAEANAIAVSVEYGLFPTRPIPACYEDSWAALQWVASHADGNGPEPWLKDHADMQRVFVAGDSAGGNVTHNLVSRVGKKGLAGAKIAGAVMVHPYFAGTEDDEMWMYMCPDNEGVNDGRMRPRTEDLGGVGCERVLVFVAEKDHLCDAGKRYVEELQKSGWGGSCELVVNWGLEHCFHVFHPQREEARHLLHKIVSFITHPN
>Ae03g02250.1
MQNNSSSSSSSSSSSTTMDSTSNDAEEVAYDIPPIMKVYKNGRIERLAGEDVVPPSLDPTTNVESKDVVISREQSISARLFLPKTARDSPNQKLPLFLYFHGGAFCIETPFSPNYHNLLNSVVSKANAIGVSVHYRRAPEHPVPTAHEDSWVALKWVASHVGGNGPDEWLNRHADFGNVFLSGDSAGANIAHYLGVRVGTEEGRLEGLKIEGLALVHPYFWGVDRVGSEADRGEFCAKVDDLWRFSCPTTSGSDDPVINPAKDPNLGKLGCGRVLVLVAGKDLLKDRGWFYKESLEKVGWSGIAQVVETKDEDHVFHMLNPTCENAMALLDQLVSFIKAK
>Ae04g25610.1
MVQEKKLVDEVSGWLRIYDDGSVDRTWTGPSEVEFMVKPVPPHEDFIDGVATRDVMMTGGANNHRARIYLPEKISGDSEKLPILLHFHGGGFCISEPDWFMYYNIYTRFTRSTRVICVSPFLRRAPESRLPAAIDDGFSTLLWLQSVARGDAEEPWLQTHGDFSRVFLIGDSSGANIVHEVAALAGKTCLDPLRVAGGIPIHPGFLRSTRSKSEMEKPQSPFLTLDMVDKFLQLALPVGSNKDHPITCPMGDNAPPLSELKLPSFLLCLAEQDLVWDTEMEYYEAMKKAQHDVELFVSKGMTHSFYLNKIAVDMEPNTGAETEALIAKVKEFIDKH
>Ae05g12100.1
MKPSNPQQSLYSPTLLQLLYQAASTLFFITTIFSVFTLIMASTTNDIVAQIPTYITVYKNGTVDRPRQTPFAPPSVPDPQTGVSSKDIAISHNPPSPISARLYLPKSINPNSSDSTTTHKLPIWVYFHGGGFFFESAFSKLYHHYFNTFVSQVDVLVVSIEYRLAPEHLLPAAYDDCWDALQWVASHFSTQNPIKTEPWLINHGDFSRIFIGGDSAGGNIVHNVAMRAGSEALHNGVKLKGAVYVHPYFYSSNPIGSEPVTGHEQSLPELVWHFIYPSAPGGIDNPMINPLAPGAPSLATLGCSKILVCVAGKDSLRDRGVWFYEGVKKSGWKGEELELFEEKEEDHVYHIFNPESDHAKKVTQVMASFILH
>Ae05g12090.1
MSSNTKETVFEIPTYLSIYNDASIDRPRNIPRVPPSPNGDPSTGVSSKDIVFSFNPLLSARLFLPDLTRTRPDQKKLPILVYFHGGAFCFESAFAEHHHTYCNIVSSKANAIIVSVEHRKAPEHYLPAAYNDCWDALKWVASHAIQNPINEFTTTITDPWLINHGDFSRIFIGGESSGANIVHNVAMRAGVEDLPNGVKLYGAYMNHPYFCGSEPVGSEPIEGYEQSLTYMVWKFVYPDAPCGIDNPMINPMVAGAPSLATLGCSKMFVSVAGKDHLYMRDRGVLYYDAVKQSGWKGEIFLFEEPQEDHVYHMFNIHSDKAKRLIRLVADFLSH
>Ae05g12110.1
MGSTSTNTKEETLYIPNLVRVFNDGSIERLQTTPFVPPSIDDPTTGGVSSKDVVISQNPSISARFYLPTTLLISNNKKVPILVYFHGGGFFFESAFNQRHHDYFNSFVSIAEELMVVSVEYRLAPETPLPAGYDDCFDALKWVATKSDPWLINHGDFQRLFIGGDSAGGNIVHNVALRVGAESLPNGVKLLGAFFSHPYFFSSEPMGSEAIEGHEQSAPYLVWDLVYPNAPGGVDNPMINPLAPGAPTLAG
>Ae07g08310.1
MENSNNNNTHEQVTQELPGIIRVFADCRVERLRGTDVVPPSLHPQSIVSSKDITLNPQSDISARVFLPPLQHSRDQKLPLLLYFHGGAFCISSPFNATYHNYLVALVSEANVIAVSVDYRLAPEHPLPAAYEDAWAALQWVALHKEKNGPEPWLNEHADFERVFLAGDSSGGNIVHNIAMIAGDSSLNPGIDILGACLVHPYFWGSSPIGSEGLDPGKKELVDRMWPFVCPSMPDNDNPWANPVAEEAPSLSWLGCRRVLVCVAEKDILRDRGWLYYNALGRSGWIGVVEIEETQEEGHAFHLYDLGCNKAKELIKCMAEFFNRDAPPSI
>Ae08g03350.1
MDSTKIPEISVEVPPYLRVHRDGTVERIAGTQVVAPGLDPQTNVASKDILLIPQTALTARLYRPHNTSSHHHKLPLVIYFHGGAFCISSAADPFYHTSLNTLVAESNAVALSVNYRLAPEHPLPTAYEDSWDAVQWVASHAAEDRQDHDPWLKESVDFDRVFLAGDSAGANIGHFIATRLHRKNNSAGPVKYFKIPGLIMVHPYFWGKEPIGAEVSDPERKRMVDTWWDFVCSSGKGCDDPLINPFVEEAPGLEDVDCHRVIVIVAEKDILKERGKLYHKNLVSSGWKGTAQLYETQGEDHDFHIFNPNTDKAKSLIKRISAFINEQD
>Ae09g23920.1
MNVQSPILFLNDGDGVDETLIIANIAVVFFFFAFFSLNVVEMASITPINHTLVKEIVSSLGSLIRIYDDGTIERPIESPLVPPNLYDPVSGISSKDIVITQNPKISARIYLPKITKPDHKIPIYTYFHGGGFLFESAFSKFYTDHHNKLLSAANVLVVSVEYRIAPETPLPACYHDCWEALKWVASHRDATTTNKTEPWLVDHGDFNRVFIGGDSAGGNIVHNIAMRAGAEALPCGLKIQGALMMHPFFFGSEPVGAEILEEHQKNSNHEVWKLAYPNAPGGIDNPMINILASGAPSLATLGCTKIVVFVAGKDCLGLRERGVWYYEAVKNSGWEGKIEFYEDEDEDHVYYMFKPECENANKMIKRMASFFLE
>Ae09g26400.1
MAALASSISLSSQYTSSTNDYHIQNHGSVAEETIEGLITVHKDGHVERPQIVPCVSSDLSPEMNVTSRDMVIDNVTNTWARFYVPIGHKKKLPLMVYFHGGGFCIGSAAWSCYHDFLARLSAKVGCLIMSVNYRLAPENPLPAPYDDGLKALMWVKQQVLYEYEASKWWAKKCNFSSVFLAGDSAGANIAYNVAIRVDEACGDGLRPLKLKGLVLIQPFFGGEERTASEKCMAQSRGSALNLVASDTYWRLALPCGADRDHPWCNPLAMKLDKLKHFLLPTLVCISEMDILKDRNLEFCDALATAGKRVEFGVFRGVGHAFQILSKSQISKNRTYEMMAHVKSFIMAMPM
>Ae09g23930.1
MASAESTATTTKEIDRELPPLLRVYKDGTVERFLGSSHVPPSPEDPDTGVSSKDIVISENPLISARLYLPKLTNHETQKLPILVYYHGGAFCLESAFSFLHQRYLNIIASEAKVLVVSIEYRLAPEHPLPAAYEDGWFSLKWVTSHSTNNPTNTEPWLINHGDFSRFYIGGDTSGANIAHNALLRIGGGLESLPGDVKISGALLAFPLFWGSKPVLNESVEGHEKSSPMQVWNFVYPDAPGGIDNPLINPLAPGAPSLATLGCPKVQIFVAGKDDLRDRGIWYYDALKKSGWKGDVEFLEVEGEEHCFQIYHPETDNSKDMISRIASFLV
>Ae0005130.1
MSIIAESPDFLQVYSDGTVKRFNPEIAPPSSEPSNNNRFKSKDVIMDHSKPITGRIFLPSSDSTTSSKKLPLLVYFHGGGFCIGSTTWLGYHAFLGDFAATSTSIVVSIDYRLAPEHRLPAAYEDCYASLKWLADQASIEPWLKHADLTRVFLSGDSAGGNITHYVALKAIQTNDCPLKIKGLLPIHPYFGSEERTKKEMEDEECLDVKSNDMFWNLSIPKGSNRDYYGCNFEKAEVDETVWSKFPAIEVYVAGLDFLKERGVMYSEFMKKKGVNEVKLVEAEGERHIFHVFYPESDATRLLQRQMSQFMKRFY
MDSASGEVAVDYSPFIKIYKDGRIQRLIGCDVVPPSHDPTTNVESKDVVISETDDISARIFIPKHHDHQNQKLPVLVYFHGGGFCIETPFSPHYHNFLNAVVSGARVIGVSVHYRRAPEHPVPIAYEDSWASLKWVASHSDGKGPDEWLNRYADLGNVFFGGDSAGANIAHHMGIRVGSEGIPGMKVQGVFLVHSYFWGEERIGSESDGSKAQHLPLVGNLWRFVCPTSAGSDDPMINPSKDPNLGKMGCERVLVFVAENDVLKDRGWHYKESIEKSGWGGAVELVETKGEGHVFHLFNPSGHNSLSLLNRVVSFIKQT
>Ae03g02210.1
MDSAAGKEVLREFPFLFRLYKDGTVERFMGTDTTPPGTDPLTHVHSKDITINPFTGVAARIYLPPTSPSAAQKLPLLIYIHGGAFCICTPYNSTYHRHINNIAAEANALVLSVHYRLAPSTPSAAYDDSWEAIQWTATHAAASGGGLEPWLNDYADFNRVFLGGDSAGANIAHNMAVRGTTEGFGGMNLEGVVLIHPYFGNEKKDELIEFLYPSYGGLDDPKIHPDKDPTVSGLGCERMLVLVAEKDFLRERGRRYYETVKKSGWGGVVEMVETEGEEHVFHLLNPTKDKSLHLVKQIASFINQHTC
>Ae03g02230.1
MATAQAKDITHEFRFFRVYSDGTVQLHRPPTQTIPPFDDLSTGLRSKDAVISTDPPVSVRLFLPRITDPTQKLPVLFYIHGGGFCMQSAFSPTYHNLVATLAAEANAIAVSVEYGLFPTRPIPACYEDSWAALQWVASHADGNGPEPWLKDHADMQRVFVAGDSAGGNVTHNLVSRVGKKGLAGAKIAGAVMVHPYFAGTEDDEMWMYMCPDNEGVNDGRMRPRTEDLGGVGCERVLVFVAEKDHLCDAGKRYVEELQKSGWGGSCELVVNWGLEHCFHVFHPQREEARHLLHKIVSFITHPN
>Ae03g02250.1
MQNNSSSSSSSSSSSTTMDSTSNDAEEVAYDIPPIMKVYKNGRIERLAGEDVVPPSLDPTTNVESKDVVISREQSISARLFLPKTARDSPNQKLPLFLYFHGGAFCIETPFSPNYHNLLNSVVSKANAIGVSVHYRRAPEHPVPTAHEDSWVALKWVASHVGGNGPDEWLNRHADFGNVFLSGDSAGANIAHYLGVRVGTEEGRLEGLKIEGLALVHPYFWGVDRVGSEADRGEFCAKVDDLWRFSCPTTSGSDDPVINPAKDPNLGKLGCGRVLVLVAGKDLLKDRGWFYKESLEKVGWSGIAQVVETKDEDHVFHMLNPTCENAMALLDQLVSFIKAK
>Ae04g25610.1
MVQEKKLVDEVSGWLRIYDDGSVDRTWTGPSEVEFMVKPVPPHEDFIDGVATRDVMMTGGANNHRARIYLPEKISGDSEKLPILLHFHGGGFCISEPDWFMYYNIYTRFTRSTRVICVSPFLRRAPESRLPAAIDDGFSTLLWLQSVARGDAEEPWLQTHGDFSRVFLIGDSSGANIVHEVAALAGKTCLDPLRVAGGIPIHPGFLRSTRSKSEMEKPQSPFLTLDMVDKFLQLALPVGSNKDHPITCPMGDNAPPLSELKLPSFLLCLAEQDLVWDTEMEYYEAMKKAQHDVELFVSKGMTHSFYLNKIAVDMEPNTGAETEALIAKVKEFIDKH
>Ae05g12100.1
MKPSNPQQSLYSPTLLQLLYQAASTLFFITTIFSVFTLIMASTTNDIVAQIPTYITVYKNGTVDRPRQTPFAPPSVPDPQTGVSSKDIAISHNPPSPISARLYLPKSINPNSSDSTTTHKLPIWVYFHGGGFFFESAFSKLYHHYFNTFVSQVDVLVVSIEYRLAPEHLLPAAYDDCWDALQWVASHFSTQNPIKTEPWLINHGDFSRIFIGGDSAGGNIVHNVAMRAGSEALHNGVKLKGAVYVHPYFYSSNPIGSEPVTGHEQSLPELVWHFIYPSAPGGIDNPMINPLAPGAPSLATLGCSKILVCVAGKDSLRDRGVWFYEGVKKSGWKGEELELFEEKEEDHVYHIFNPESDHAKKVTQVMASFILH
>Ae05g12090.1
MSSNTKETVFEIPTYLSIYNDASIDRPRNIPRVPPSPNGDPSTGVSSKDIVFSFNPLLSARLFLPDLTRTRPDQKKLPILVYFHGGAFCFESAFAEHHHTYCNIVSSKANAIIVSVEHRKAPEHYLPAAYNDCWDALKWVASHAIQNPINEFTTTITDPWLINHGDFSRIFIGGESSGANIVHNVAMRAGVEDLPNGVKLYGAYMNHPYFCGSEPVGSEPIEGYEQSLTYMVWKFVYPDAPCGIDNPMINPMVAGAPSLATLGCSKMFVSVAGKDHLYMRDRGVLYYDAVKQSGWKGEIFLFEEPQEDHVYHMFNIHSDKAKRLIRLVADFLSH
>Ae05g12110.1
MGSTSTNTKEETLYIPNLVRVFNDGSIERLQTTPFVPPSIDDPTTGGVSSKDVVISQNPSISARFYLPTTLLISNNKKVPILVYFHGGGFFFESAFNQRHHDYFNSFVSIAEELMVVSVEYRLAPETPLPAGYDDCFDALKWVATKSDPWLINHGDFQRLFIGGDSAGGNIVHNVALRVGAESLPNGVKLLGAFFSHPYFFSSEPMGSEAIEGHEQSAPYLVWDLVYPNAPGGVDNPMINPLAPGAPTLAG
>Ae07g08310.1
MENSNNNNTHEQVTQELPGIIRVFADCRVERLRGTDVVPPSLHPQSIVSSKDITLNPQSDISARVFLPPLQHSRDQKLPLLLYFHGGAFCISSPFNATYHNYLVALVSEANVIAVSVDYRLAPEHPLPAAYEDAWAALQWVALHKEKNGPEPWLNEHADFERVFLAGDSSGGNIVHNIAMIAGDSSLNPGIDILGACLVHPYFWGSSPIGSEGLDPGKKELVDRMWPFVCPSMPDNDNPWANPVAEEAPSLSWLGCRRVLVCVAEKDILRDRGWLYYNALGRSGWIGVVEIEETQEEGHAFHLYDLGCNKAKELIKCMAEFFNRDAPPSI
>Ae08g03350.1
MDSTKIPEISVEVPPYLRVHRDGTVERIAGTQVVAPGLDPQTNVASKDILLIPQTALTARLYRPHNTSSHHHKLPLVIYFHGGAFCISSAADPFYHTSLNTLVAESNAVALSVNYRLAPEHPLPTAYEDSWDAVQWVASHAAEDRQDHDPWLKESVDFDRVFLAGDSAGANIGHFIATRLHRKNNSAGPVKYFKIPGLIMVHPYFWGKEPIGAEVSDPERKRMVDTWWDFVCSSGKGCDDPLINPFVEEAPGLEDVDCHRVIVIVAEKDILKERGKLYHKNLVSSGWKGTAQLYETQGEDHDFHIFNPNTDKAKSLIKRISAFINEQD
>Ae09g23920.1
MNVQSPILFLNDGDGVDETLIIANIAVVFFFFAFFSLNVVEMASITPINHTLVKEIVSSLGSLIRIYDDGTIERPIESPLVPPNLYDPVSGISSKDIVITQNPKISARIYLPKITKPDHKIPIYTYFHGGGFLFESAFSKFYTDHHNKLLSAANVLVVSVEYRIAPETPLPACYHDCWEALKWVASHRDATTTNKTEPWLVDHGDFNRVFIGGDSAGGNIVHNIAMRAGAEALPCGLKIQGALMMHPFFFGSEPVGAEILEEHQKNSNHEVWKLAYPNAPGGIDNPMINILASGAPSLATLGCTKIVVFVAGKDCLGLRERGVWYYEAVKNSGWEGKIEFYEDEDEDHVYYMFKPECENANKMIKRMASFFLE
>Ae09g26400.1
MAALASSISLSSQYTSSTNDYHIQNHGSVAEETIEGLITVHKDGHVERPQIVPCVSSDLSPEMNVTSRDMVIDNVTNTWARFYVPIGHKKKLPLMVYFHGGGFCIGSAAWSCYHDFLARLSAKVGCLIMSVNYRLAPENPLPAPYDDGLKALMWVKQQVLYEYEASKWWAKKCNFSSVFLAGDSAGANIAYNVAIRVDEACGDGLRPLKLKGLVLIQPFFGGEERTASEKCMAQSRGSALNLVASDTYWRLALPCGADRDHPWCNPLAMKLDKLKHFLLPTLVCISEMDILKDRNLEFCDALATAGKRVEFGVFRGVGHAFQILSKSQISKNRTYEMMAHVKSFIMAMPM
>Ae09g23930.1
MASAESTATTTKEIDRELPPLLRVYKDGTVERFLGSSHVPPSPEDPDTGVSSKDIVISENPLISARLYLPKLTNHETQKLPILVYYHGGAFCLESAFSFLHQRYLNIIASEAKVLVVSIEYRLAPEHPLPAAYEDGWFSLKWVTSHSTNNPTNTEPWLINHGDFSRFYIGGDTSGANIAHNALLRIGGGLESLPGDVKISGALLAFPLFWGSKPVLNESVEGHEKSSPMQVWNFVYPDAPGGIDNPLINPLAPGAPSLATLGCPKVQIFVAGKDDLRDRGIWYYDALKKSGWKGDVEFLEVEGEEHCFQIYHPETDNSKDMISRIASFLV
>Ae0005130.1
MSIIAESPDFLQVYSDGTVKRFNPEIAPPSSEPSNNNRFKSKDVIMDHSKPITGRIFLPSSDSTTSSKKLPLLVYFHGGGFCIGSTTWLGYHAFLGDFAATSTSIVVSIDYRLAPEHRLPAAYEDCYASLKWLADQASIEPWLKHADLTRVFLSGDSAGGNITHYVALKAIQTNDCPLKIKGLLPIHPYFGSEERTKKEMEDEECLDVKSNDMFWNLSIPKGSNRDYYGCNFEKAEVDETVWSKFPAIEVYVAGLDFLKERGVMYSEFMKKKGVNEVKLVEAEGERHIFHVFYPESDATRLLQRQMSQFMKRFY
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University