Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Clethra arborea
Species name
Folhado (Clethra arborea) is a species of eudicot in the family Clethraceae.
Species info
Gene sequence info
Clethra_arborea.4CL.fa
Download
>carb_03667-RA
RQIQRVLTSLLYHHPQKCPPSSPRPLQHTNSNTHTHTHTHSQLTTVTSRRLHPIQNHLLPSAMEKSGYGRDGIFRSLRPPLLLPRDPNLSLVSFLFRNSSSYPDKPALIDADNHHSSSSTLNFSQFKSAVAKFSHALLHLGIAKNDVVLIFAPNSTQFPISFFGVIAIGAIATTVNPLYTVTEISKQIKDCNPKLIITVPQLFEKVKGFGISSVILGSKNSNSAIVDSSNSKVYWFVDLVKNDGSVLDLPKASIKSSDTAALLYSSGTTGLSKGVVLSHGNFVAAALMVTSDQELAGEMHSVYLCVLPMFHVFGLAVIMYSQLQRGNAVVSMAKFDLEAVLRAVERYRVTHLWIVPPIVLALAKNSVVKKYDLSSLRQIGSGAAPLGKDLMADCAKNFAQAVVMQGFGMTETCGIVSVENPRQGPRHSGSAGRLVPGVECQIVSVDTMKPLPPKQLGEIWVRGANMMQGYFNNPQATRLTIDKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHSEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQKFIANQVAPFKRLRRVTFVNSVPKSASGKILRRELIEKVRSKL
>carb_15737-RA
MENQKCRQDDQFIFRSKLPDIYVPNHLPLHSYCFENISEFSSRPCLIDGATGKTHTYADVELTARKVAAGLHNIGLRQGDVVMLLLQNSPEFVFAFLGASYGGATSTTANPFYTAAEIEKQAKASRAKIIITQACYAEKVMGYARENDVKVVCTDSPPEGCLHFSELTRAEESDLPAVKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVIMCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFEINSLLQLVHKHKVTIAPFVPPIVLAIAKSPVVDNYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPDTGAFLPRNQAGEICIRGDQIMKGYLNDPEATERTIDKEKWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPNISDAAVVPMKDEAAGEVPVAFVNNELLGDINLQVVFYKRISRVFFADTIPKAPSGKILRKDLRAKLAAGFPN
>carb_16880-RA
MLTHRNLVANLCSTLFSIKPEMIGHVTTLGLMPFFHIYGMTGICCATLKNKGKVVVMGRYKVETFLGALIEHEVTFAPIVPAIILDMVRNRVVDDFDLSKLKLMAVMTAAAPLAPEVLKKGHRPAKKNSVGFILPNLELKFVDPNTGRSLPKNSRGELCVRSQCVMQGYYRNEEVTAQTIDGNGWLHTGDIGYIDDDGDVAPAHLENILLTHPSVADAAVIPEEEIMSYVASHVASYERVRVVQFVDAIPRSDSGKILRRLLKEKMVKRMKTDNPKFGQHC
>carb_23436-RA
MEKKDDIIFRSKLPDIYIPNHLPLHSYCFENISQFSSKPCLIDGPTGKTYTYSDVELNSRKVAAGLHNLGIKQHDTIMLLLPNSPEFVFAFLGSSFLGATTTMANPFFTAAEVLKQAKASAAKLIVTQSCHLEKVLAHAQDNKFKIACIDAPPPAAANEEICFHFSKLAQSDEREMPEVEIDPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYINSDDVMMCVLPLFHIYSLNSVLLCGLRVGAAILIVQKFEIVSFLGMVERYGVTIGPFVPPIVLAIAKSPAVEDYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGNSLPRNQPGEICIRGDQIMKGYLNDPEATENTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDESAGEVPVAFVVRSNGSEITEDEVKKYISKQVVFYKRINRVFFTDAIPKAPSGKILRKDLRAILAAGIPN
>carb_27724-RA
MLSVASVETKKPELSAQVIPSTPPDQTREETHVFRSKLPEIPISNHLPLHTYCFENLSQFPDRTCLIVGSTGKSYSFAETHLVSRKVAAGLSNLGIGKGDVVMLLLQNCAEFVFSFMGASMIGAVTTTANPFYTAAEVFKQFAASKSKLIITHSQYVDKLLDAGDSFPKLGEDFTLITIDDPPENCLHFSVLSEANESEIPSVSIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLTTEDMVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPMVEAFDLSSIRMVLSGAAPLGKELEEALRSRVPQAVFGQGYGMTEAGPVLSMSLAFAKQPFQTKSGSCGTVVRNAELKVIDPETGCSLPQNQSGEICIRGLQIMKGYLNDADSTAATIDVDGWLHTGDIGYVDDDDEVFIVDRVKELIKFKGFQACLSVPPAELEALLLTEEAVKEFIAKQVVFYKKLHKVYFVHAIPKSPSGKILRKDLRAKLATGSQIP
RQIQRVLTSLLYHHPQKCPPSSPRPLQHTNSNTHTHTHTHSQLTTVTSRRLHPIQNHLLPSAMEKSGYGRDGIFRSLRPPLLLPRDPNLSLVSFLFRNSSSYPDKPALIDADNHHSSSSTLNFSQFKSAVAKFSHALLHLGIAKNDVVLIFAPNSTQFPISFFGVIAIGAIATTVNPLYTVTEISKQIKDCNPKLIITVPQLFEKVKGFGISSVILGSKNSNSAIVDSSNSKVYWFVDLVKNDGSVLDLPKASIKSSDTAALLYSSGTTGLSKGVVLSHGNFVAAALMVTSDQELAGEMHSVYLCVLPMFHVFGLAVIMYSQLQRGNAVVSMAKFDLEAVLRAVERYRVTHLWIVPPIVLALAKNSVVKKYDLSSLRQIGSGAAPLGKDLMADCAKNFAQAVVMQGFGMTETCGIVSVENPRQGPRHSGSAGRLVPGVECQIVSVDTMKPLPPKQLGEIWVRGANMMQGYFNNPQATRLTIDKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHSEILDAVVIPFPDAEAGEVPIAYVVRSPNSSLTEEDVQKFIANQVAPFKRLRRVTFVNSVPKSASGKILRRELIEKVRSKL
>carb_15737-RA
MENQKCRQDDQFIFRSKLPDIYVPNHLPLHSYCFENISEFSSRPCLIDGATGKTHTYADVELTARKVAAGLHNIGLRQGDVVMLLLQNSPEFVFAFLGASYGGATSTTANPFYTAAEIEKQAKASRAKIIITQACYAEKVMGYARENDVKVVCTDSPPEGCLHFSELTRAEESDLPAVKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYFHSEDVIMCVLPLFHIYSLNSVLLCGLRVGAAILIMQKFEINSLLQLVHKHKVTIAPFVPPIVLAIAKSPVVDNYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPDTGAFLPRNQAGEICIRGDQIMKGYLNDPEATERTIDKEKWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLIAHPNISDAAVVPMKDEAAGEVPVAFVNNELLGDINLQVVFYKRISRVFFADTIPKAPSGKILRKDLRAKLAAGFPN
>carb_16880-RA
MLTHRNLVANLCSTLFSIKPEMIGHVTTLGLMPFFHIYGMTGICCATLKNKGKVVVMGRYKVETFLGALIEHEVTFAPIVPAIILDMVRNRVVDDFDLSKLKLMAVMTAAAPLAPEVLKKGHRPAKKNSVGFILPNLELKFVDPNTGRSLPKNSRGELCVRSQCVMQGYYRNEEVTAQTIDGNGWLHTGDIGYIDDDGDVAPAHLENILLTHPSVADAAVIPEEEIMSYVASHVASYERVRVVQFVDAIPRSDSGKILRRLLKEKMVKRMKTDNPKFGQHC
>carb_23436-RA
MEKKDDIIFRSKLPDIYIPNHLPLHSYCFENISQFSSKPCLIDGPTGKTYTYSDVELNSRKVAAGLHNLGIKQHDTIMLLLPNSPEFVFAFLGSSFLGATTTMANPFFTAAEVLKQAKASAAKLIVTQSCHLEKVLAHAQDNKFKIACIDAPPPAAANEEICFHFSKLAQSDEREMPEVEIDPNDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYINSDDVMMCVLPLFHIYSLNSVLLCGLRVGAAILIVQKFEIVSFLGMVERYGVTIGPFVPPIVLAIAKSPAVEDYDLSSVRTVMSGAAPLGKELEDAVRAKFPNAKLGQGYGMTEAGPVLAMCLAFAKEPFEIKSGACGTVVRNAEMKIVDPETGNSLPRNQPGEICIRGDQIMKGYLNDPEATENTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLNHPNISDAAVVPMKDESAGEVPVAFVVRSNGSEITEDEVKKYISKQVVFYKRINRVFFTDAIPKAPSGKILRKDLRAILAAGIPN
>carb_27724-RA
MLSVASVETKKPELSAQVIPSTPPDQTREETHVFRSKLPEIPISNHLPLHTYCFENLSQFPDRTCLIVGSTGKSYSFAETHLVSRKVAAGLSNLGIGKGDVVMLLLQNCAEFVFSFMGASMIGAVTTTANPFYTAAEVFKQFAASKSKLIITHSQYVDKLLDAGDSFPKLGEDFTLITIDDPPENCLHFSVLSEANESEIPSVSIDPDDAVALPFSSGTTGLPKGVILTHKSLITSVAQQVDGENPNLYLTTEDMVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGALLELIQRHRVSVAAVVPPLVLALAKNPMVEAFDLSSIRMVLSGAAPLGKELEEALRSRVPQAVFGQGYGMTEAGPVLSMSLAFAKQPFQTKSGSCGTVVRNAELKVIDPETGCSLPQNQSGEICIRGLQIMKGYLNDADSTAATIDVDGWLHTGDIGYVDDDDEVFIVDRVKELIKFKGFQACLSVPPAELEALLLTEEAVKEFIAKQVVFYKKLHKVYFVHAIPKSPSGKILRKDLRAKLATGSQIP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University