Enzyme
Catalyses the final step in the formation of the isoflavonoid skeleton. The reaction also occurs spontaneously.
HIDH
Enzyme
2-hydroxyisoflavanone dehydratase
Enzyme name
EC:4.2.1.105
Entry
Lyases;Carbon-oxygen lyases;Hydro-lyases
Class
2,4',7-trihydroxyisoflavanone hydro-lyase (daidzein-forming)
Sysname
(1) 2,4',7-trihydroxyisoflavanone = daidzein + H2O [RN:R07317];(2) 2,4',5,7-tetrahydroxyisoflavanone = genistein + H2O
Reaction
daidzein [CPD:C10208];H2O [CPD:C00001];genistein [CPD:C06563]
Product
Species information
Citrullus lanatus
Species name
Wild melon (Citrullus lanatus) is a species of eudicot in the family Cucurbitaceae (cucumber family).
Species info
Gene sequence info
Citrullus_lanatus.HIDH.fa
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>Cla97C01G014100.1
MGSLPHIVEDCMGVLQLYSDGTVFRSDDIHFPFPITVDTSVVFRDVLYDASHGLHLRLFKPAAATSTNKKLPILFFFHGGGFCVGSRSWPNSHNCCVRLALGLEALVIAPDYRLAPEHRLPAAVEDGAKAIEWARKREDAWIEEGGDLERVFVMGDSSGGNIAHHLAVRIGMESEKFGVKGFVLMAPFFGGVTRTQSEEGPPEEFFDLEALDR
>Cla97C02G050290.1
MATIPFEVDECRGVLRVYSDGSIVRSSNPSFNVPVFDDGSVLWKDLLFDPIHHLHLRLYKPAAISSSKLPVFFYIHGGGFCIGSRTWPNCQNYCFRLAAELPALVISPDYRLAPENRLPAAIDDGFTALRWLQAQAVSDHPDPWLADVADFSRVFISGDSAGGNIAHHLAAGLGLGSPELAPVRVRGYVLLAPFFGGTMRTRSEAEGSKEAFLNLELIDRFWRLSIPIGSSTDHPLVNVFGPRSRNLEALEMDPIMVVVGGADLLKDRAVEYEEKLKKQGKKIELVEFEGKQHGFFTIDPNSEASNQLMLLINHFVAQHSL
>Cla97C05G104780.1
MRTTRMPTINLDQIPSFEEHGNGFDQHDVLVEEIEGLIRVYGNGYVERPQIVPCVSNALPPELGVTSWDVVVDKLNNLWARFYVPTQCQEKLPLIVYFHGGGFCVGSAAWSCYHEFLAKLSAKADCIIMSVNYRLAPENPLPAPYEDGLKTLQWLKQVAFVGAKQNWWSRYCDFTKIYLSGDSAGGNIAFNVAARLGGKMTATGAVVLKPLVIKGSILIQPFFGGESRTKSEKFLVQPPRSPLTLAVSDTYWRLALPSGTNRDHAWCNPSAKGLFKVEDLRVLPSLICISEMDILKDRNLEFCSALHRAGKLINYVVYEGVGHAFQVLNKSQLSQTRTLEMIDHIKDFLCV
>Cla97C05G098080.1
MALVGEAPGFFEVYSDGSVRRLIPEVVVSTDTQSSKNYKFKDVIIDSKKLVTGRLFLPNVTKSATKLPILVYFHGGGFCIGSTTWIGYHNFLGDLTVASESVVLSIDYRLAPENRLPAAYEDCYNSLEWLSYEASSEPLLQNADLSRVFLSGDSAGGNIVHHVAVKTIKSNISNLTIKGLLLIHPYFGSEKRTENEKAQGAKGFVEMNDMFWRLSIPTGRDRDYFGCNYENNAEEVSKEEWGRFPNVVVFVAGLDFLKERGELYAKFLQKMRVKEVKLIEAADESHVYHVFHPESEATRLLQKQMSQFMKSY
>Cla97C07G143200.1
MAAISMDPRLKLQMPKLRIQNEATVEEIEGLIRVYADGHVERPPIIPNVSCSTTASDKGVTAKDVIIGNFTNTWARIYVVNSQRNLPLLVYFHGGGFCVGSAAWSCYHEFLLDLASKAKCVILSVNYRLSPENRLPAAYEDGYNTLMWLKQQAITNPIEHKWWLGNCNPSKLFLAGDSAGANIAYNIATRLGLNEPTILKPLTLKGIILIQPFFGGESRTKSEKLAAQPSSASALTLDAADTYWRLSLPPGANRDHTWSNPVANGGAKLRETKVPPLMVCISELDILVDRNLEFCAAMSAAGKKVERVILKGVGHSFQILNKDQISSLRRQEMMGCIQAFLQQ
>Cla97C08G159270.1
MASGEPETAFELLPLLRVYKNGRIERLVGTDFVPPGTDPLTGVTSKDVTILPEFSVSARLFLPKLTHSTQRLPLVVYFHGGCFCTQSPFTAKYHSYLNALTAEARVVAVSVNYRKAPEHPVPTAYEDSWAALQWAISHRDGKGPEIWLNEHVDFRRVFLAGASAGANIAHNLAMVAGDPDCGANMELIGVALEHPYFWGSVRTGKEAENPVKARLFDQLWGFVCPARPENDDPWLNPVVEGAAGLAGMGSGRVLVCVAEKDVLRDRGRLYFEALGSSGWLGVAEIEETEGEDHMFHLNDLEGQKAKDLIQRLGDFFNRDMPLSLLL
>Cla97C08G153600.1
MTKGKTLILDVSGWLRLFDDGSVDRTWTGPPEVKFVAESVPPHDELIDGVAVRDLVIDQNSGLRVRIYLPEVKCGGGKKLPVVVHFHGGGFCISEADWFMYYHTYTNFVKSAEAICVSVYLRRAPEHRLPAAIDDGFSALKWLQSVALGNEIEPWIAENADFNRVFLIGDSSGGNLVHSVAALAGETDLTPLKLAGGIPIHPGFVRAKRSKSEIENPQSPFLTLDMVDKFLSLALPVGSSKDHPITCPMGIDAPPLEKLNLPPFLLCIAEKDLIIDTEMEYYEAMKAANKEVEILMSKGMGHSFYLNKIAMKMDPETAAESDHLFAGIARFIKQH
>Cla97C09G178860.1
MDSEAGDGDGVVFEFLPAFRVFKSGRVQRLFPDDRLPPSTDPLTGVQSKDILIDPQTQLSVRIFLPHVSHSTKKLPLLIYIHGGAFSIGSVATPIYHHHLISLAAEANAVALSVEYRLAPEHPLPAAYDDAWAAVEWAASHSNGNGEEIWLNQHADFNHVSVVGDSAGANISYNVVVRASESNNGAKGMKISGLGLVHPFFMIDKPDKLIDYIFPTSSGLDDPRLNPWANPKLGKLRCERVLILAADLDLLKDRAHGFYAALRENGFEGSVEMVETQGEDHVFHLFNPNTHNAIALLKKLASFIQSMDGVGTLTSHL
>Cla97C09G178820.1
MYLDTSISIHVSHLLAEISSDSPFHLLFFIFFILLSDFAMASDEIAINAAPYFIFYKDGRIDRLIGNDIDPPGLDPKTGVESKDVDISPDVTVRVYRPKSAAGKQAQKLPLLVYFHGGGFCIETAFSPFYHQHINAWVAEGNIAAVSVNYRRAPEYQLPIPFEDSWTAMKWIAAHSGGKGPDEWLNEIADLNQVYLAGDSAGGNIAHRMALRVGTEGLDGVKIKGLQLIHPHFWGEKLIGEEQEWDRKDLFVVENLWFMVSKDIKNLDHPIVNPEHDPDLGRLAAERVAVYVAEKDNLKVRGRHYAECLKKSGWKGTVEVVETTGEGHVFHLFNPTCDMAGELVKQLAAFTSSGRSG
>Cla97C09G178830.1
MASTEISHNFSPMLIVYKDGRAHRLAGNELVDPSLDPLTGVESKDVVISPETAVSARIYRPKPTAQSHKLPLLVYIHGGGFCIESAFSPTYHRHLNSLVAEANVVAVSVEYRRAPEHPLPIAYEDTWAALKWVAAHSARTGSEEWLNGIADLDRVYFAGDSAGANIANQMAIRVRTEGVSGLNLRGLILVHPYFWGGKLIGDEEKLNPEDRSFIEKLWYLVCPTISGLDDPIVNPEFEPKLGLVAAERVTVYVAEKDALKDRGWFYSECLKKSGWGGAVDVVETKGQGHVFHLFNPTSNEAVDFVGKLAAFINGGRPE
>Cla97C09G178840.1
MASSINKTDDVAFDLFPFFRIYKDGRVQRLQIASDIVPADADDPKSAFRSKDVTILADPAISVRIFIPSSADPNRKLPLILYVHGGAFCFESAFNLQYHTHVGSLATKANAVAVSVEYRLTPEHPIAACYDDCWDALRWVATHVNRDGPEPWLNKHADLDRICLAGDSAGANICHHLAARAGSSAEQLGGVKVVGMALIHPFFGDGGDDRLWKFLCSDQTRPVRPSIEELAKLPCRRVKVFLAEEDFLKFGGRNYDEDLKRSGWNGAVETVEHDGEGHVFHLKKPQCEKALDLLEQLSTFINLD
>Cla97C09G178850.1
MDSQEDEIEFEFLPVFRVFKNGRVHRLLLTDRIPPSTDQLTGVQSKDFLIDPKTGVSVRLYLPKLSDSTKKLPLLIYIHGGAFSVGSPASPMFHNHLISLTAQANAVAVSVDYRLAPENNLPAAYEDAWTAVEWAASHSSLSGPEIWLNQHADFNRVFVVGESAGANISYNVMDRASENEDGVKVKGMKIIGLGLVHPYFMIDKPDKLIEYIFPTSAGLEDPRLNPKANPRVGKFGCSRVLICAAEIDPLKYGAVGVHAAFKESGFEGSVEMMETKGEDHGFHLFNPHTQNAQMLLTKIASFIQSPLS
MGSLPHIVEDCMGVLQLYSDGTVFRSDDIHFPFPITVDTSVVFRDVLYDASHGLHLRLFKPAAATSTNKKLPILFFFHGGGFCVGSRSWPNSHNCCVRLALGLEALVIAPDYRLAPEHRLPAAVEDGAKAIEWARKREDAWIEEGGDLERVFVMGDSSGGNIAHHLAVRIGMESEKFGVKGFVLMAPFFGGVTRTQSEEGPPEEFFDLEALDR
>Cla97C02G050290.1
MATIPFEVDECRGVLRVYSDGSIVRSSNPSFNVPVFDDGSVLWKDLLFDPIHHLHLRLYKPAAISSSKLPVFFYIHGGGFCIGSRTWPNCQNYCFRLAAELPALVISPDYRLAPENRLPAAIDDGFTALRWLQAQAVSDHPDPWLADVADFSRVFISGDSAGGNIAHHLAAGLGLGSPELAPVRVRGYVLLAPFFGGTMRTRSEAEGSKEAFLNLELIDRFWRLSIPIGSSTDHPLVNVFGPRSRNLEALEMDPIMVVVGGADLLKDRAVEYEEKLKKQGKKIELVEFEGKQHGFFTIDPNSEASNQLMLLINHFVAQHSL
>Cla97C05G104780.1
MRTTRMPTINLDQIPSFEEHGNGFDQHDVLVEEIEGLIRVYGNGYVERPQIVPCVSNALPPELGVTSWDVVVDKLNNLWARFYVPTQCQEKLPLIVYFHGGGFCVGSAAWSCYHEFLAKLSAKADCIIMSVNYRLAPENPLPAPYEDGLKTLQWLKQVAFVGAKQNWWSRYCDFTKIYLSGDSAGGNIAFNVAARLGGKMTATGAVVLKPLVIKGSILIQPFFGGESRTKSEKFLVQPPRSPLTLAVSDTYWRLALPSGTNRDHAWCNPSAKGLFKVEDLRVLPSLICISEMDILKDRNLEFCSALHRAGKLINYVVYEGVGHAFQVLNKSQLSQTRTLEMIDHIKDFLCV
>Cla97C05G098080.1
MALVGEAPGFFEVYSDGSVRRLIPEVVVSTDTQSSKNYKFKDVIIDSKKLVTGRLFLPNVTKSATKLPILVYFHGGGFCIGSTTWIGYHNFLGDLTVASESVVLSIDYRLAPENRLPAAYEDCYNSLEWLSYEASSEPLLQNADLSRVFLSGDSAGGNIVHHVAVKTIKSNISNLTIKGLLLIHPYFGSEKRTENEKAQGAKGFVEMNDMFWRLSIPTGRDRDYFGCNYENNAEEVSKEEWGRFPNVVVFVAGLDFLKERGELYAKFLQKMRVKEVKLIEAADESHVYHVFHPESEATRLLQKQMSQFMKSY
>Cla97C07G143200.1
MAAISMDPRLKLQMPKLRIQNEATVEEIEGLIRVYADGHVERPPIIPNVSCSTTASDKGVTAKDVIIGNFTNTWARIYVVNSQRNLPLLVYFHGGGFCVGSAAWSCYHEFLLDLASKAKCVILSVNYRLSPENRLPAAYEDGYNTLMWLKQQAITNPIEHKWWLGNCNPSKLFLAGDSAGANIAYNIATRLGLNEPTILKPLTLKGIILIQPFFGGESRTKSEKLAAQPSSASALTLDAADTYWRLSLPPGANRDHTWSNPVANGGAKLRETKVPPLMVCISELDILVDRNLEFCAAMSAAGKKVERVILKGVGHSFQILNKDQISSLRRQEMMGCIQAFLQQ
>Cla97C08G159270.1
MASGEPETAFELLPLLRVYKNGRIERLVGTDFVPPGTDPLTGVTSKDVTILPEFSVSARLFLPKLTHSTQRLPLVVYFHGGCFCTQSPFTAKYHSYLNALTAEARVVAVSVNYRKAPEHPVPTAYEDSWAALQWAISHRDGKGPEIWLNEHVDFRRVFLAGASAGANIAHNLAMVAGDPDCGANMELIGVALEHPYFWGSVRTGKEAENPVKARLFDQLWGFVCPARPENDDPWLNPVVEGAAGLAGMGSGRVLVCVAEKDVLRDRGRLYFEALGSSGWLGVAEIEETEGEDHMFHLNDLEGQKAKDLIQRLGDFFNRDMPLSLLL
>Cla97C08G153600.1
MTKGKTLILDVSGWLRLFDDGSVDRTWTGPPEVKFVAESVPPHDELIDGVAVRDLVIDQNSGLRVRIYLPEVKCGGGKKLPVVVHFHGGGFCISEADWFMYYHTYTNFVKSAEAICVSVYLRRAPEHRLPAAIDDGFSALKWLQSVALGNEIEPWIAENADFNRVFLIGDSSGGNLVHSVAALAGETDLTPLKLAGGIPIHPGFVRAKRSKSEIENPQSPFLTLDMVDKFLSLALPVGSSKDHPITCPMGIDAPPLEKLNLPPFLLCIAEKDLIIDTEMEYYEAMKAANKEVEILMSKGMGHSFYLNKIAMKMDPETAAESDHLFAGIARFIKQH
>Cla97C09G178860.1
MDSEAGDGDGVVFEFLPAFRVFKSGRVQRLFPDDRLPPSTDPLTGVQSKDILIDPQTQLSVRIFLPHVSHSTKKLPLLIYIHGGAFSIGSVATPIYHHHLISLAAEANAVALSVEYRLAPEHPLPAAYDDAWAAVEWAASHSNGNGEEIWLNQHADFNHVSVVGDSAGANISYNVVVRASESNNGAKGMKISGLGLVHPFFMIDKPDKLIDYIFPTSSGLDDPRLNPWANPKLGKLRCERVLILAADLDLLKDRAHGFYAALRENGFEGSVEMVETQGEDHVFHLFNPNTHNAIALLKKLASFIQSMDGVGTLTSHL
>Cla97C09G178820.1
MYLDTSISIHVSHLLAEISSDSPFHLLFFIFFILLSDFAMASDEIAINAAPYFIFYKDGRIDRLIGNDIDPPGLDPKTGVESKDVDISPDVTVRVYRPKSAAGKQAQKLPLLVYFHGGGFCIETAFSPFYHQHINAWVAEGNIAAVSVNYRRAPEYQLPIPFEDSWTAMKWIAAHSGGKGPDEWLNEIADLNQVYLAGDSAGGNIAHRMALRVGTEGLDGVKIKGLQLIHPHFWGEKLIGEEQEWDRKDLFVVENLWFMVSKDIKNLDHPIVNPEHDPDLGRLAAERVAVYVAEKDNLKVRGRHYAECLKKSGWKGTVEVVETTGEGHVFHLFNPTCDMAGELVKQLAAFTSSGRSG
>Cla97C09G178830.1
MASTEISHNFSPMLIVYKDGRAHRLAGNELVDPSLDPLTGVESKDVVISPETAVSARIYRPKPTAQSHKLPLLVYIHGGGFCIESAFSPTYHRHLNSLVAEANVVAVSVEYRRAPEHPLPIAYEDTWAALKWVAAHSARTGSEEWLNGIADLDRVYFAGDSAGANIANQMAIRVRTEGVSGLNLRGLILVHPYFWGGKLIGDEEKLNPEDRSFIEKLWYLVCPTISGLDDPIVNPEFEPKLGLVAAERVTVYVAEKDALKDRGWFYSECLKKSGWGGAVDVVETKGQGHVFHLFNPTSNEAVDFVGKLAAFINGGRPE
>Cla97C09G178840.1
MASSINKTDDVAFDLFPFFRIYKDGRVQRLQIASDIVPADADDPKSAFRSKDVTILADPAISVRIFIPSSADPNRKLPLILYVHGGAFCFESAFNLQYHTHVGSLATKANAVAVSVEYRLTPEHPIAACYDDCWDALRWVATHVNRDGPEPWLNKHADLDRICLAGDSAGANICHHLAARAGSSAEQLGGVKVVGMALIHPFFGDGGDDRLWKFLCSDQTRPVRPSIEELAKLPCRRVKVFLAEEDFLKFGGRNYDEDLKRSGWNGAVETVEHDGEGHVFHLKKPQCEKALDLLEQLSTFINLD
>Cla97C09G178850.1
MDSQEDEIEFEFLPVFRVFKNGRVHRLLLTDRIPPSTDQLTGVQSKDFLIDPKTGVSVRLYLPKLSDSTKKLPLLIYIHGGAFSVGSPASPMFHNHLISLTAQANAVAVSVDYRLAPENNLPAAYEDAWTAVEWAASHSSLSGPEIWLNQHADFNRVFVVGESAGANISYNVMDRASENEDGVKVKGMKIIGLGLVHPYFMIDKPDKLIEYIFPTSAGLEDPRLNPKANPRVGKFGCSRVLICAAEIDPLKYGAVGVHAAFKESGFEGSVEMMETKGEDHGFHLFNPHTQNAQMLLTKIASFIQSPLS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University