Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Citrullus lanatus
Species name
Wild melon (Citrullus lanatus) is a species of eudicot in the family Cucurbitaceae (cucumber family).
Species info
Gene sequence info
Citrullus_lanatus.4CL.fa
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>Cla97C02G034290.1
MISIAQNPNVSSELSSSPPPSTATTHTFRSKFPDITIPDHLPLHSYCFQNLSEVSHRPCLILGSTGKSYSYSDTHLFSLKAAATFSKLGVKKGDIIMILLHNSPEFVFSFMASSMLGAVATTANPYYTAAEISKQLKASGAKFVVTYSQCVDKLKESGEHLTIVTVDDPPENCLSFSMVYDADVNDVPSVEIDTNDAVSLPFSSGTTGLPKGVILTHKNMVSSVAQQVDGENPNLYLRRNDVVLCVLPMFHIFSLSSIVLISIRSGAALLLMEKFEIESLLRLIERHEVTVAAVVPPLVVALVKNPRLADFDLSSIRLVLSGAAPLRKELEEALMERLPQAIFGQGYGMTEAGPVLSMCSAFAKEPLMPTKSGSCGRVVRNSELKVIDPQTGDSLTYNQPGEICVRGPQVMKGYLNDPVSTSLTVDVEGWLHTGDIGYIDDEDEIFIVDRVKEIIKFKGFQVAPAELEALLVTHPSIVDAAVVPQSDDVAGEVPVAFVVPSTQDELTEDAVKEFIAKQVVFYKRLQKVYFVQTIPKSPSGKILRKELKTKLSVSPGF
>Cla97C03G053800.1
MEKSGYGRDGIFRSLRPPLVFPKDPNLSMISFLFRNSCSYPNRLAIVDAESSDSVSYSQLKASAIRVSNGLIQLGIEKNDVVLIFAPNSVQFSVCFIGIIAIGAIVTTCNPVYTVSELTKQVKDAKPKLVISVAELWDKVKDLNIPTVLLDQQIPSAIHSSKILCFNDLMNMAGDKSGSEFPIVGVKQSDTAALLYSSGTTGASKGVILTHRNFITSSLMITMDQTFRGEEHGVYLNFLPMFHVFGLACITYAQLQKGNSIVSMPKFNLEKALWAVEKYKVTDMWVVPPVVLALAKQSVVKKYNLSSVKRVGSGAAPLGKELMEECANNIPSAVVLQGYGMTETCGVVALENPEVGKRNSGSAGTLASGVEAKIVSVDTLKPLPPNQYGEIHVRGPNMMRGYFNNPEATKQTIDKYGWVHTGDLGYFDENGQLYVVDRIKELIKYKGFQVAPAELEALLVSHPEILDAVVIPYPDAEAGEVPIAYVVRSANSSLTEEDILKFIADQVSPYKRLRRVTFISSVPKSVSGKILRRELIEKVRAKI
>Cla97C06G122680.1
MAADDDSSPEFIFRSKLPDIAIPTHLPLHSYCFEKISEFKYRPCLINAATGNTYTYDEVHITSRRVTAGLHKLGIGKGDVIMLLLQNTPQFVLAFLGASYLGAATTPANPFFTPAEIAKQAMSSGAKLIITQAAFAEKVKKLSQENKAIIKVIFIDDDPPPDGGYHFSSLTDEVAKEEEREMGDVKISPDDVVALPYSSGTTGLPKGVMLTHKALVTSVAQQVDGENPHLYIRSDDVVLCVLPLFHIYSLNSIMMCSLRVGAAILIVQKFDVNSLLELIPKYRVTIAPIVPPIVLAIAKSPALDHYDMSSIRIVMSGAAPLGKTLEDAFRAKLPHVILGQGYGMTESGSAMTMSLAFAKERFEIKSGGCGTLMRNSEMKIVNPQTGASLPRNQAGEICIRSPQIMKGYLNDEEATKGIIDKDGWLHTGDIGFVDDDDEVFIVDRLKELIKYKGFQVAPAELEALLISHGRIADAAVIPMKDEVAGEVPVAFIVRSDGSKITEDEIKQYISKQVVFYKRINRVFFVDSIPKSQSGKILRRQLRVLLAASIPN
>Cla97C09G165820.1
MAVESNQTNEFIFRSKLPHIHIPNHLPLHEYVFQNLPKFASRPCLINGATGDVYSYSDLHLTARRVAAGLHSLGINKGDVVMNLLPNSPEFVFTFLAASYRGAIMTAANPFYTAVEIAKQAKAANAKLIVTMACFYDRVKDLAENGVKIVCVDFAVEGCLHFSVLSGADESNAPPVDFSPDDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQMDGQNPNLYYHGDDAILCVLPFFHIYSLNSILLCGLRVGAAIVIMQKFDIVSLLQLIEKYRISIMPIVPPIFLAIAKSPEFEKYDVSSVRVLKSGGAPLGKELEDAVREKFPAAVLGQGYGMTEAGPVLSMSLAFAKEPFEVKAGACGTVVRNAEMKIVDPETGASLPANSAGEICIRGDQIMKGYLNDLESTKRTIDKEGWLHTGDIGFVDDDDEIFIVDRLKELIKFKAFQVAPAELEALLITHPKLSDAAVIGMPDMEAGEVPVAFVVKANGGAISEEEVKQFITKQVVFYKRLKRVFFVNAIPKAPSGKILRKELRTKLASGAYN
>Cla97C09G165830.1
MKGYLNDLESTKRTIDKEGWLHTGDIGFVDDDDEIFIVDRLKELIKFKAFQVAPAELEALLITHPKLSDAAVIGMPDVEAGEVPVAFVVKANGGAITEEEVKQFITKQVVFYKRLKRVFFVNAIPKAPSGKILRKELRAKLASAAYN
>Cla97C09G165840.1
MALKSKQTNEFIFRSKLPDIYIPNHLPLHDYVFQNLPKFASRPCLINSATGDVYSFHDVHLTARRVAAGLHNLGIKKGDVVMNLLPNSPEFVFTFLAASYRGAIMTAANPFYTAVEIAKQVKAANAKLIVTMACFYDRVKDLAENGVKIVCVDFAVEGCLHFSVLTGADESHSPPVDFSPEDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQMDGQNPNLYYHRDDVILCVLPFFHIYSLNSILLCGLRAGAAIMIMQKFEIISLLQLIEKYKISIMPIVPPILLAIAKSSEFEKYDVSSVRVLKSGGAPLGKELEDAVRAKFPAAILGQGYGMTEAGPVLTMSLAFAKEPFQVKAGACGTVVRNAEMKIVDPETGASLPANSAGEICIRGDQIMKGYLNDLESTKRTIDKEGWLHTGDMGYIDDDDELFIVDRLKELIKFKAFQVAPAEVEALLISHPKLCDAAVIGMPDVEAGEVPVAFVVKENSDTITEEEVKQFITKQVVFYKRLKRVFFVNAIPKAPSGKILRKELRAKFASAAYN
>Cla97C10G195660.1
MLLLPNSPEFVFAFLGASYLGAIMTAANPFFTAAEIAKQAKGSKSKLIVTQSSYYEKVKEITEELANVKIMTVDSPPEGCLWFGDLIKAEEGDTPRVEIDPDDVVALPYSSGTTGLPKGVMLTHKSLVTSVAQQVDGENPNLYYGNEDVILCVLPLFHIYSLNSVLLCGLRAGAAILIMPKFEIGLLLQLVERYRVSIAPIVPPIVLAIAKSPDLEKYDLSSIRVIKCGGAPLGKELEDTVRAKFPKAVLGQGYGMTEAGPVLTMGLAFAKEPFPMKPGACGTVVRNAEMKIVDTETGSSLPRNTPGEICIRGDQIMKGYLNNPEATAATIDKDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPVISDAAVVPMKDEQAGEVPVAFVVKLKNSEVTEDEIKLFVSKQVVFYKRINRVFFIDAIPKSPSGKILRKELRAKLAAGFPNSN
>Cla97C10G203230.1
MAITLRKSFNSQSQIYTSRRPPIHFPTDPTISIPSFLFRNSSSFPNALALADSDSGESLTFRQLQIQVSKLAHVFIQLGIRKSDVVLIFAPNSIHFPVCFFAIVAIGAIATTCNPAYTFGELSKQVANCNPKLVITVPELWDTIGKLNLPSIILGSKISSKFSRPNIWGYSDLIKKAGDVSNLPVSEVGQNDVAALLYSSGTTGISKGVILTHRNFITTSLMVTQDQDLLGDPRNVFLCFLPMFHVFGLSIIVYSQLQRGNTVVSMAKFELEKALGVVMKYRITHLYVVPPVIIALTKQSVVKNYDLSSLKQILSGAAPLGKDVMEECSKFIPQARIIQGYGMTETCGVISVGNVGVESTLSGATGSLVSGVEAQVLSTETQKRLPPGETGEICVRGPNMMKGYFNNQEATSKTIDDQGWVHTGDIGYFNEEGELFVVDRIKELIKCYGFQVAPAELEALLLSHPQITDAIVIPYPDDKAGEVPIAFVVRSPHSSIKEEDVKNFIAGQVAPYKRLKRVTFTSSVPKSVSGKLLRREVIAQVRAKM
>Cla97C11G219500.1
MATCIRDLVEEEEHIFRSQLPEVQVPDNITLPEFVLQNAESYAENVAFVEAVSGKAYTYREVVRDINRFSKALCSLRLKKGQVVIVVLPNVAEYAIVALGIMAAGGVFSGVNPAAHISEIKKQVEVAEAKLVVTNSANFEKVKELKLPVILLGEELIEGSINWHKLLEAADRAGNDCVKEDIKQTDLCALPFSSGTTGVSKGVMLTHRNLIANLCSTLSGVPREIEGKVTTLGLIPFFHIYGITGICCAALRNKGKVVVMGRFDLRTFINALITQEVTFAPIVPPIILALVKNPIVEEFDLSGLKLQAIMTAAAPLAPEVQTAFERKFPGVDIQEAYGLTEHSCITLNYGSMGKDNLTAKKNTVGRILPNLEVKFIDPDSGRSLPKNTPGEICVRSQCVMQGYYKNEEETSRTIDNKGWMHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLAHPSIEDAAVVPLPDEEAGEIPAASVVMAPNSKETEDEIIKHVASNVAHYKKVRLVHFVDTIPKSPSGKVMRRLIKEKMLEKIRAESAS
MISIAQNPNVSSELSSSPPPSTATTHTFRSKFPDITIPDHLPLHSYCFQNLSEVSHRPCLILGSTGKSYSYSDTHLFSLKAAATFSKLGVKKGDIIMILLHNSPEFVFSFMASSMLGAVATTANPYYTAAEISKQLKASGAKFVVTYSQCVDKLKESGEHLTIVTVDDPPENCLSFSMVYDADVNDVPSVEIDTNDAVSLPFSSGTTGLPKGVILTHKNMVSSVAQQVDGENPNLYLRRNDVVLCVLPMFHIFSLSSIVLISIRSGAALLLMEKFEIESLLRLIERHEVTVAAVVPPLVVALVKNPRLADFDLSSIRLVLSGAAPLRKELEEALMERLPQAIFGQGYGMTEAGPVLSMCSAFAKEPLMPTKSGSCGRVVRNSELKVIDPQTGDSLTYNQPGEICVRGPQVMKGYLNDPVSTSLTVDVEGWLHTGDIGYIDDEDEIFIVDRVKEIIKFKGFQVAPAELEALLVTHPSIVDAAVVPQSDDVAGEVPVAFVVPSTQDELTEDAVKEFIAKQVVFYKRLQKVYFVQTIPKSPSGKILRKELKTKLSVSPGF
>Cla97C03G053800.1
MEKSGYGRDGIFRSLRPPLVFPKDPNLSMISFLFRNSCSYPNRLAIVDAESSDSVSYSQLKASAIRVSNGLIQLGIEKNDVVLIFAPNSVQFSVCFIGIIAIGAIVTTCNPVYTVSELTKQVKDAKPKLVISVAELWDKVKDLNIPTVLLDQQIPSAIHSSKILCFNDLMNMAGDKSGSEFPIVGVKQSDTAALLYSSGTTGASKGVILTHRNFITSSLMITMDQTFRGEEHGVYLNFLPMFHVFGLACITYAQLQKGNSIVSMPKFNLEKALWAVEKYKVTDMWVVPPVVLALAKQSVVKKYNLSSVKRVGSGAAPLGKELMEECANNIPSAVVLQGYGMTETCGVVALENPEVGKRNSGSAGTLASGVEAKIVSVDTLKPLPPNQYGEIHVRGPNMMRGYFNNPEATKQTIDKYGWVHTGDLGYFDENGQLYVVDRIKELIKYKGFQVAPAELEALLVSHPEILDAVVIPYPDAEAGEVPIAYVVRSANSSLTEEDILKFIADQVSPYKRLRRVTFISSVPKSVSGKILRRELIEKVRAKI
>Cla97C06G122680.1
MAADDDSSPEFIFRSKLPDIAIPTHLPLHSYCFEKISEFKYRPCLINAATGNTYTYDEVHITSRRVTAGLHKLGIGKGDVIMLLLQNTPQFVLAFLGASYLGAATTPANPFFTPAEIAKQAMSSGAKLIITQAAFAEKVKKLSQENKAIIKVIFIDDDPPPDGGYHFSSLTDEVAKEEEREMGDVKISPDDVVALPYSSGTTGLPKGVMLTHKALVTSVAQQVDGENPHLYIRSDDVVLCVLPLFHIYSLNSIMMCSLRVGAAILIVQKFDVNSLLELIPKYRVTIAPIVPPIVLAIAKSPALDHYDMSSIRIVMSGAAPLGKTLEDAFRAKLPHVILGQGYGMTESGSAMTMSLAFAKERFEIKSGGCGTLMRNSEMKIVNPQTGASLPRNQAGEICIRSPQIMKGYLNDEEATKGIIDKDGWLHTGDIGFVDDDDEVFIVDRLKELIKYKGFQVAPAELEALLISHGRIADAAVIPMKDEVAGEVPVAFIVRSDGSKITEDEIKQYISKQVVFYKRINRVFFVDSIPKSQSGKILRRQLRVLLAASIPN
>Cla97C09G165820.1
MAVESNQTNEFIFRSKLPHIHIPNHLPLHEYVFQNLPKFASRPCLINGATGDVYSYSDLHLTARRVAAGLHSLGINKGDVVMNLLPNSPEFVFTFLAASYRGAIMTAANPFYTAVEIAKQAKAANAKLIVTMACFYDRVKDLAENGVKIVCVDFAVEGCLHFSVLSGADESNAPPVDFSPDDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQMDGQNPNLYYHGDDAILCVLPFFHIYSLNSILLCGLRVGAAIVIMQKFDIVSLLQLIEKYRISIMPIVPPIFLAIAKSPEFEKYDVSSVRVLKSGGAPLGKELEDAVREKFPAAVLGQGYGMTEAGPVLSMSLAFAKEPFEVKAGACGTVVRNAEMKIVDPETGASLPANSAGEICIRGDQIMKGYLNDLESTKRTIDKEGWLHTGDIGFVDDDDEIFIVDRLKELIKFKAFQVAPAELEALLITHPKLSDAAVIGMPDMEAGEVPVAFVVKANGGAISEEEVKQFITKQVVFYKRLKRVFFVNAIPKAPSGKILRKELRTKLASGAYN
>Cla97C09G165830.1
MKGYLNDLESTKRTIDKEGWLHTGDIGFVDDDDEIFIVDRLKELIKFKAFQVAPAELEALLITHPKLSDAAVIGMPDVEAGEVPVAFVVKANGGAITEEEVKQFITKQVVFYKRLKRVFFVNAIPKAPSGKILRKELRAKLASAAYN
>Cla97C09G165840.1
MALKSKQTNEFIFRSKLPDIYIPNHLPLHDYVFQNLPKFASRPCLINSATGDVYSFHDVHLTARRVAAGLHNLGIKKGDVVMNLLPNSPEFVFTFLAASYRGAIMTAANPFYTAVEIAKQVKAANAKLIVTMACFYDRVKDLAENGVKIVCVDFAVEGCLHFSVLTGADESHSPPVDFSPEDVVALPYSSGTTGLPKGVMLTHKGLITSVAQQMDGQNPNLYYHRDDVILCVLPFFHIYSLNSILLCGLRAGAAIMIMQKFEIISLLQLIEKYKISIMPIVPPILLAIAKSSEFEKYDVSSVRVLKSGGAPLGKELEDAVRAKFPAAILGQGYGMTEAGPVLTMSLAFAKEPFQVKAGACGTVVRNAEMKIVDPETGASLPANSAGEICIRGDQIMKGYLNDLESTKRTIDKEGWLHTGDMGYIDDDDELFIVDRLKELIKFKAFQVAPAEVEALLISHPKLCDAAVIGMPDVEAGEVPVAFVVKENSDTITEEEVKQFITKQVVFYKRLKRVFFVNAIPKAPSGKILRKELRAKFASAAYN
>Cla97C10G195660.1
MLLLPNSPEFVFAFLGASYLGAIMTAANPFFTAAEIAKQAKGSKSKLIVTQSSYYEKVKEITEELANVKIMTVDSPPEGCLWFGDLIKAEEGDTPRVEIDPDDVVALPYSSGTTGLPKGVMLTHKSLVTSVAQQVDGENPNLYYGNEDVILCVLPLFHIYSLNSVLLCGLRAGAAILIMPKFEIGLLLQLVERYRVSIAPIVPPIVLAIAKSPDLEKYDLSSIRVIKCGGAPLGKELEDTVRAKFPKAVLGQGYGMTEAGPVLTMGLAFAKEPFPMKPGACGTVVRNAEMKIVDTETGSSLPRNTPGEICIRGDQIMKGYLNNPEATAATIDKDGWLHTGDIGFIDDDDELFIVDRLKELIKYKGFQVAPAELEALLLTHPVISDAAVVPMKDEQAGEVPVAFVVKLKNSEVTEDEIKLFVSKQVVFYKRINRVFFIDAIPKSPSGKILRKELRAKLAAGFPNSN
>Cla97C10G203230.1
MAITLRKSFNSQSQIYTSRRPPIHFPTDPTISIPSFLFRNSSSFPNALALADSDSGESLTFRQLQIQVSKLAHVFIQLGIRKSDVVLIFAPNSIHFPVCFFAIVAIGAIATTCNPAYTFGELSKQVANCNPKLVITVPELWDTIGKLNLPSIILGSKISSKFSRPNIWGYSDLIKKAGDVSNLPVSEVGQNDVAALLYSSGTTGISKGVILTHRNFITTSLMVTQDQDLLGDPRNVFLCFLPMFHVFGLSIIVYSQLQRGNTVVSMAKFELEKALGVVMKYRITHLYVVPPVIIALTKQSVVKNYDLSSLKQILSGAAPLGKDVMEECSKFIPQARIIQGYGMTETCGVISVGNVGVESTLSGATGSLVSGVEAQVLSTETQKRLPPGETGEICVRGPNMMKGYFNNQEATSKTIDDQGWVHTGDIGYFNEEGELFVVDRIKELIKCYGFQVAPAELEALLLSHPQITDAIVIPYPDDKAGEVPIAFVVRSPHSSIKEEDVKNFIAGQVAPYKRLKRVTFTSSVPKSVSGKLLRREVIAQVRAKM
>Cla97C11G219500.1
MATCIRDLVEEEEHIFRSQLPEVQVPDNITLPEFVLQNAESYAENVAFVEAVSGKAYTYREVVRDINRFSKALCSLRLKKGQVVIVVLPNVAEYAIVALGIMAAGGVFSGVNPAAHISEIKKQVEVAEAKLVVTNSANFEKVKELKLPVILLGEELIEGSINWHKLLEAADRAGNDCVKEDIKQTDLCALPFSSGTTGVSKGVMLTHRNLIANLCSTLSGVPREIEGKVTTLGLIPFFHIYGITGICCAALRNKGKVVVMGRFDLRTFINALITQEVTFAPIVPPIILALVKNPIVEEFDLSGLKLQAIMTAAAPLAPEVQTAFERKFPGVDIQEAYGLTEHSCITLNYGSMGKDNLTAKKNTVGRILPNLEVKFIDPDSGRSLPKNTPGEICVRSQCVMQGYYKNEEETSRTIDNKGWMHTGDIGYIDDDGDVFIVDRIKELIKYKGFQVAPAELEAILLAHPSIEDAAVVPLPDEEAGEIPAASVVMAPNSKETEDEIIKHVASNVAHYKKVRLVHFVDTIPKSPSGKVMRRLIKEKMLEKIRAESAS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University