Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Aeschynomene evenia
Species name
Aeschynomene evenia is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Aeschynomene_evenia.CHS.fa
Download
>Ae03g16280.1
MVSVEEIRKAQRAEGPATVLAIGTANPTNCVEQSTYPDFYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPKICEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPLPEIEKPLFELVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEVKLGLKPEKMEATRHVLSEYGNMSSACVLFILDEIRRKSKENGLATTGEGLDWGVLFGFGPGLTVETVVLRSVAN
>Ae04g35570.1
MGDEGILRGVPKHANPGKATVLALGKAFPHQLVMQEYLVDGYFRDTNCDNLELKQKLSRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLEICNKAVTQMAIEASQVCIKNWGRSLSDITHLVYVSSSEARLPGGDLYLARGLGLSPSTQRVLLYFAGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIVGTDPIVGTEKPLFELHTAVQEFLPDTEKKIDGRLTEEGISFKLARELPQIIEDNVEGFCEKLMGVVGFQNKDYNKLFWAVHPGGPAILNRIEKRLDLLPEKLNASRRALMDYGNASSNTIVYVLEYMIEEAKKIRNDGEDDPEWGLMLAFGPGITFEGILARNLCD
>Ae05g11110.1
MVSVSEIRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPEIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAI
>Ae05g06090.1
MASSRVNEIRNAQRAEGPATVMAIGTANPPNCVDQTTYPDFYFRITNSDHKTELKQKFKRMCKHIIVKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLGLKPEKMEATRHVLSEYGNMSSACVLFILDEMRKKSAQNGLATTGEGLEWGVLFGFGPGLTVETVSIKLQCDNTTYPIISANFSRSLQ
>Ae05g11080.1
MVSVSEIRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPQIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAI
>Ae05g11540.1
MVSVSEIRKAQRAEGPATILAIGTANPSNCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPEIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLEWGVLFGFGPGLTIETVVLHSVAI
>Ae05g11120.1
MVSVSEIRKAQRAEGPATILAIGTANPANCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPQIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAI
>Ae05g11530.1
MVSVSEIRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAASKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPQIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLEWGVLFGFGPGLTIETVVLHSVAI
>Ae05g11090.1
MDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPQIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAV
>Ae06g16680.1
MVSVEEIRNAQRAKGPATILAIGTANPSNCVNQDEYPDFYFRITNSEHMTDLKEKFKRMCDKSMIKKRYMHLTEEFLKENPNMCAYMEPSLDVRQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSMVGQALFGDGAAAMIIGADPDVAVERPIFQMVTAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLMEAFTPIGISDWNSIFWIAHPGGPAILDQVEAKLQLKEEKLRATRHVLGEYGNMSSACVIFILDEMRKKSVEQGKRTTGEGLDWGVLFGFGPGLTVETVVLRSVPLEA
>Ae07g19430.1
MLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTNPVLGQESPFMELNYAVQKFLPDTQNVIDGRLSEEGINFKLGRDLPQKIDDNIEEFCRKLMAKSNIKEFNDLFWAVHPGGPAILNKLEGTLKLSSDKLDCSRKALMDYGNVSSNTIFYVMEYMREYLKEDGREEWGLGLAFGPGITFEGILLRSL
>Ae08g08940.1
MGTSQQIREAQRAKGVATVLAIGTANPPNFILQSDYPDFYFRVTKNDHMTDLKHKFTRICKNSMIEKRHFLYDEDFLQQNSNISTYGAPSMDARHSILREEVPKLGKEAALKAIAEWNQPLSKITHLIFYTTSCFGNIPSSDYHLANLLGLEPTLNRLMIFNTGCQAGGTVLRVAKDIAENNANSRVLVVWVETMMASFHAPNANHMDVVVGQALFGDGAAAVIIGADPDPSIESPLFELVHASQNTVPNSENEIRVGPKEMGLVYYLGKDIPKFVSENIEKSLIDAFNSIGVDSSSIDWNTLFYALHPGGPAILSEIEQKLGLHIDKLRANWHVLKQYGNMWGPTVIFVLDEIRNWSTKEGKSTTGEGLEWGVLAGFGPGLSLEIIVLRSIHI
>Ae08g08920.1
MNEMAYLEKIRETQRGRGPATILAIGTATPSNYIYQSDFTDYYFRVTNSDHMTQLKAKLKRICEKSMIKKRYVHLTEEMLKQNPNICAYNEPSLDARQDMLVEEVPKLGSKAASKALKEWARPKSDITHLIFCSTSGVDMPGADYQLIKLLGLSPSTKRFMLYHQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITVVTFRGPSETHLDSLVGQALFGDGASSVIVGSDPDRSIERPLFHLVAASETILPNSEGAIEGHLREVGLTFHLKENVPTLIGENIEKSLEEMFHPLGISDWNSLFWVAHPGGPAILGEIERRLGLKEDKLRATKHVLGEYGNMSSACVLFILDEMRRRSMQEGRGTTGEGLKWGVLCGFGPGLTMETIALHSAAIDKGC
>Ae08g08930.1
MTTMSAKQQIGEVQRRDKRVATILAIGTANPPNFILQSDYPDFYFRVTKSDHMTDLKHKFNRICKNSMIEKRHFLYDEDFLQQNSNISTYGAPSMDARHSILREEVPKLGKEAALKAIAEWNQPLSKITHLIFYTTSCFGNIPSSDYHLANLLGLEPTLNRLMIFNTGCQAGGTVLRVAKDIAENNVASRVLVVWVETMMASFHAPNTNHMDVVVGQALFGDGAAAVIIGADPDPSIEFPLFELVHASQNTVPNSENVIHGGPKEMGLVYYLGKDIPKFVSENIEKSLLDAFSSIGVDSATIDWSTLFYALHSGGPAILSQIEQKLGLHTDKLRANWHVLNQYGNMWGPTVIFVLDEMRKWSKKEGKSTSGEGLEWGVLAGFGPGLSLEIIVLRSASYL
MVSVEEIRKAQRAEGPATVLAIGTANPTNCVEQSTYPDFYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPKICEYMAPSLDARQDMVVVEVPKLGKEAATKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAAVIVGSDPLPEIEKPLFELVWTAQTILPDSEGAIDGHLREVGLTFHLLKDVPGLISKNIEKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEVKLGLKPEKMEATRHVLSEYGNMSSACVLFILDEIRRKSKENGLATTGEGLDWGVLFGFGPGLTVETVVLRSVAN
>Ae04g35570.1
MGDEGILRGVPKHANPGKATVLALGKAFPHQLVMQEYLVDGYFRDTNCDNLELKQKLSRLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLEICNKAVTQMAIEASQVCIKNWGRSLSDITHLVYVSSSEARLPGGDLYLARGLGLSPSTQRVLLYFAGCSGGVAGLRVAKDIAENNPGSRVLLATSETTIIGFKPPSADRPYDLVGVALFGDGAGAMIVGTDPIVGTEKPLFELHTAVQEFLPDTEKKIDGRLTEEGISFKLARELPQIIEDNVEGFCEKLMGVVGFQNKDYNKLFWAVHPGGPAILNRIEKRLDLLPEKLNASRRALMDYGNASSNTIVYVLEYMIEEAKKIRNDGEDDPEWGLMLAFGPGITFEGILARNLCD
>Ae05g11110.1
MVSVSEIRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPEIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAI
>Ae05g06090.1
MASSRVNEIRNAQRAEGPATVMAIGTANPPNCVDQTTYPDFYFRITNSDHKTELKQKFKRMCKHIIVKALVEAFQPLGISDYNSIFWIAHPGGPAILDQVEAKLGLKPEKMEATRHVLSEYGNMSSACVLFILDEMRKKSAQNGLATTGEGLEWGVLFGFGPGLTVETVSIKLQCDNTTYPIISANFSRSLQ
>Ae05g11080.1
MVSVSEIRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPQIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAI
>Ae05g11540.1
MVSVSEIRKAQRAEGPATILAIGTANPSNCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPEIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLEWGVLFGFGPGLTIETVVLHSVAI
>Ae05g11120.1
MVSVSEIRKAQRAEGPATILAIGTANPANCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRYMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPQIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAI
>Ae05g11530.1
MVSVSEIRKAQRAEGPATILAIGTANPPNCVEQSTYPDFYFRITNSEHKTELKEKFQRMCDKSMIKKRYMYLTEEILKENPNICEYMAPSLDARQDMVVVEVPRLGKEAASKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPYVKRFMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPQIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLEWGVLFGFGPGLTIETVVLHSVAI
>Ae05g11090.1
MDLAENNKGARVLVVCSEVTAVTFRGPTDTHLDSLVGQALFGDGAAAVIVGSDPVPQIEKPIFELVWTAQTIAPDSEGAIDGHLREVGLTFHLLKDVPGIVSKNIDKALVEAFDPLGISDYNSIFWIAHPGGPAILDQVEAKLALKPEKMRATRQILSDYGNMSSACVLFILDEMRKKSAEQGLKTTGEGLDWGVLFGFGPGLTIETVVLHSVAV
>Ae06g16680.1
MVSVEEIRNAQRAKGPATILAIGTANPSNCVNQDEYPDFYFRITNSEHMTDLKEKFKRMCDKSMIKKRYMHLTEEFLKENPNMCAYMEPSLDVRQDIVVVEVPKLGKEAATKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSMVGQALFGDGAAAMIIGADPDVAVERPIFQMVTAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGIISKNIEKSLMEAFTPIGISDWNSIFWIAHPGGPAILDQVEAKLQLKEEKLRATRHVLGEYGNMSSACVIFILDEMRKKSVEQGKRTTGEGLDWGVLFGFGPGLTVETVVLRSVPLEA
>Ae07g19430.1
MLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGTNPVLGQESPFMELNYAVQKFLPDTQNVIDGRLSEEGINFKLGRDLPQKIDDNIEEFCRKLMAKSNIKEFNDLFWAVHPGGPAILNKLEGTLKLSSDKLDCSRKALMDYGNVSSNTIFYVMEYMREYLKEDGREEWGLGLAFGPGITFEGILLRSL
>Ae08g08940.1
MGTSQQIREAQRAKGVATVLAIGTANPPNFILQSDYPDFYFRVTKNDHMTDLKHKFTRICKNSMIEKRHFLYDEDFLQQNSNISTYGAPSMDARHSILREEVPKLGKEAALKAIAEWNQPLSKITHLIFYTTSCFGNIPSSDYHLANLLGLEPTLNRLMIFNTGCQAGGTVLRVAKDIAENNANSRVLVVWVETMMASFHAPNANHMDVVVGQALFGDGAAAVIIGADPDPSIESPLFELVHASQNTVPNSENEIRVGPKEMGLVYYLGKDIPKFVSENIEKSLIDAFNSIGVDSSSIDWNTLFYALHPGGPAILSEIEQKLGLHIDKLRANWHVLKQYGNMWGPTVIFVLDEIRNWSTKEGKSTTGEGLEWGVLAGFGPGLSLEIIVLRSIHI
>Ae08g08920.1
MNEMAYLEKIRETQRGRGPATILAIGTATPSNYIYQSDFTDYYFRVTNSDHMTQLKAKLKRICEKSMIKKRYVHLTEEMLKQNPNICAYNEPSLDARQDMLVEEVPKLGSKAASKALKEWARPKSDITHLIFCSTSGVDMPGADYQLIKLLGLSPSTKRFMLYHQGCFAGGTVLRLAKDLAENNAGARVLVVCSEITVVTFRGPSETHLDSLVGQALFGDGASSVIVGSDPDRSIERPLFHLVAASETILPNSEGAIEGHLREVGLTFHLKENVPTLIGENIEKSLEEMFHPLGISDWNSLFWVAHPGGPAILGEIERRLGLKEDKLRATKHVLGEYGNMSSACVLFILDEMRRRSMQEGRGTTGEGLKWGVLCGFGPGLTMETIALHSAAIDKGC
>Ae08g08930.1
MTTMSAKQQIGEVQRRDKRVATILAIGTANPPNFILQSDYPDFYFRVTKSDHMTDLKHKFNRICKNSMIEKRHFLYDEDFLQQNSNISTYGAPSMDARHSILREEVPKLGKEAALKAIAEWNQPLSKITHLIFYTTSCFGNIPSSDYHLANLLGLEPTLNRLMIFNTGCQAGGTVLRVAKDIAENNVASRVLVVWVETMMASFHAPNTNHMDVVVGQALFGDGAAAVIIGADPDPSIEFPLFELVHASQNTVPNSENVIHGGPKEMGLVYYLGKDIPKFVSENIEKSLLDAFSSIGVDSATIDWSTLFYALHSGGPAILSQIEQKLGLHTDKLRANWHVLNQYGNMWGPTVIFVLDEMRKWSKKEGKSTSGEGLEWGVLAGFGPGLSLEIIVLRSASYL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University