Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Aeschynomene evenia
Species name
Aeschynomene evenia is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Aeschynomene_evenia.4CL.fa
Download
>Ae01g25780.1
MEEEQPQQPTPSQDIIFRSKLPDIPIPTHLPLHSYCFQNLPQFHDRPCLIDAHTGATLTYSDVHLATLRIAAGLNTIGIQQGDVVMLLLRNCPDFALAFLGASRRGAAVTTANPFYTPAELAKQITATKTRLVITQSAYVEKIKDLAHEKNVMIMCIDSTEEQEKKDGVLNFSVLKNANEKEAPEVNIAPDDVVAIPFSSGTSGLPKGVMLTHRNLVTTVAQLVDGENPHQYTHGEDVLLCVLPMFHIYALNSILLCGIRAGAAVLIVEKFEMTALLEVVQRYRVTVASLVPPIVLALVKSGDAHRYDLSSIRAVITGAAPMGVDLQDAVKARLPHAVLGQGYGMTEAGPLAISLAFAKEAYKVKSGACGSVVRNAEMKIVDPDTGASLPRNKPGEVCIRGTKVMKGYLNDPEATERTIEKEGWLHTGDIGYMDDDDELFIVDRLKELIKYKGFQVPPAELEALLIAHPHISDAAVVPMKDEAAGEIPVAFVVKSNGSNITEDEIKQYISQQVVFYKRINRVFFTDTIPKAPSGKILRKVLTARVNQVLVAN
>Ae01g25790.1
MAPTKSDDDFIFRSKLPDIYIPTHLPLHTYCFENLSQFKHRPCLINATTGDTFSYAAVELTARKVAAGLNKLGIQQGDVILLLLQNCPQFVFAFLGASYRGATVTTANPFYTPAEVAKQATASNTKLIITQSSFIEKVKDLAIDSNVKIMCIDAPPPSNHGGYSYLHQFSELTEADEGEIPAVKISAEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYLKSEDVILCVLPLFHIYSLNSVLLCGLRVGAAIVIMHKFEIVSLLEVVQKHKVSVAPFVPPIVLAIAKSPEVQRCDLSSIRMVMSGAAPMGKDLEDAVRAKLPNATLGQGYGMTEAGPVLCMSLAFAKEPFEVKSGACGTVVRNAQMKIVDPETGASLPRNHAGEICIRGNQIMKGYLNDREATEGTIDRERWLHTGDIGYVDGNDEVFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVAMKDEAAGEVPVAYVVRSNGSKTSEDEIKQYISKQVVFYKRINKVFFVDSIPKAPSGKILRKDLRARLAAGLAV
>Ae04g29520.1
MQKSGYGSDGIYRSLRPSITLPNNPKTSLTSFLFHQTSPFPSKPALIDATTSETLTFHHLKTTVTKLSHGLLRHGLTKNDVVLIFAPNSIHFPLFFLAATAIGAIVSTVNPLYTVSELSKQINDSNPKLLITTPELLEKVKSFKFDLPTVLLGSETTSSEFTTQSRLIELAPSTTELPVNDVNQNDTAALLYSSGTTGVSKGVILTHRNFIAASLSIGMDDDVAGDANDSIFLCVLPMFHVFALAVILYSQLRRGITMVSLGRFEFEAFLKAIEKFRVTDIWVVPPIVLALAKQSVVQNYDLSSLRRIGSGAAPLGKDLMKDCARRLPHLTLIQGYGMTETCGIISVENPRTGIRHSGSAGMLAASIDARIVSVDTQESLPPTQLGEILVRGANMMKGYYKNPEATKLTIDKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQIAPAELEGLLVSHPEILDAVVIPYPDDEAGEVPVACVVRSPNSSLTEEDVQKFIADQVAPYKRLRRVTFISAIPKTASGKILRRELIAKARSKM
>Ae04g36280.1
MLLPVEISHNLDTTSPKSSYHHKQKSQSTHIFKSKLPDIPLTNTIPLHTYCFQKLPQVADRPCLIAAATGKVYTYADTHLASRSFAAGLHTLGIQKGDVIMILLPNTPEFVFSFMATSMLGAVATTANPAYTSTEIMKQIKASKAKMVITQAMQVEKIKQEDDTFTVITVDDPPKNCMKFSAVCVDEKLLPEVDINPDDTVALPFSSGTTGLPKGVVLTHRSIVTSTIQVVDGENPNLYYKEEDVLLCLLPLFHIYAMHCVMLCALRRGSSVLLVERFEIKKLLELIQRHRVSVAMVVPPLVLALAKNPAVAEYDLSSIRMIMSGAASLGKDLEEALRARLPQAVIAQAYGMTESGPVISMSMAFAKNAVVAPKRGSCGSVVRNAELKIVDIQSGASLPYCKAGEICIRGQQIMKGYLDDEKATAAAVDAEGWLHTGDIGYVDYDHDIFIVDRLKEIIKFKGFQVPPAELEGILVSHPSIADAAVVPKEDDVTGEVPVAFVVRSSNGFDLTEHDVKEFIAKQVVFYKRLHGVYFINAIPKSPSGKISRKELKAKLAATS
>Ae05g11160.1
MLSVAPSVDSAKQSTELSSSPKDAIPPPTEQKQPSPQTTHIFKSRLPDIPISNHLPLHTYCFERLSEFSDRPCLIVGSAAKTYTYAETYLASQKIAAGLSSLGIKKGDVIMILLQNSAEFVLSFIAASMIGAVATTANPFYTSAEIFKQIAASKSKLVITMAMYVDKLREQDAVNSLKLGEDFKVITVDDPPENCLHFSVISEGNENEVPEVEIRPEDAVALPFSSGTTGLPKGVVLTHKSLTTSVAQQVDGENPNLYLKAEDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMQKFEIGALLELIQKYKVSVAMVVPPLVLALAKNPMVAGYDLSSIRLVLSGAAPLGKELEEALRSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGFSLGYNQPGEICIRGQQIMKGYLNDDKATATTIDIEGWLHTGDVGYIDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVAAGEVPVAFVVRSNGFDLTEEAVKDFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLENNTTQTL
>Ae06g29720.1
MGTNIENIVQGEDEHIFHSQFEPVPVPDDVTLPEFVLQQAELYADKVAFVDAVTEKKITYSEVVRDTQRFSKALRSIGVRKGHVVIVVLPNVVEYGIIALGIMGAGGVFSGANPASHASEIKKQADSADAKLIVTNDTHYEKVKGLELPVIVLSDERVGGAMNWKKLLEAADRAGSDDFKKEQIHQNDLCAMPFSSGTTGLSKGVMLTHRNLVANLCSTLFGVGKEMIGQVTTLGLIPFFHIYGITGICCATLKSKGKVVVMGRFELKTFLNALITHEVTFAPIVPPIILSLVKNPIVNEFDLTKLKLQAIMTAAAPLAPELLTAFEHKFPGVIVQEAYGLTEHSCITLTHAQKSSAILHKTSVGFILPNLEVKFIDPDTGRSLPRNTHGELCVRSQCVMQGYYKQVDETTQTIDKNGWLHTGDIGFIDDEENIFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAASVVLSKGANESEEDIMNHVASNAAHYKKVRVVHFVEAIPKSPSGKIMRRLIKDRMVEKIKAKSTNKSNSS
>Ae06g16470.1
MLLPVEISHNLDTQLKSTSPKTSHHHKQKSQTTHIFKSKLPDIPLTNTIPLHTYCFQKLPQVADRPCLITAATGKVYTYADTHLASRSFAAGLHNLGIRKGDVIMILLPNTPEFVFSFMAASMLGAAATTANPAYTSTEIMKQIKASKAKMVITQAMQVEKVKEKQEEDDTFVVITVDDPPAENCMKFSAVCVDEELPEVDIDPDDTVALPFSSGTTGLPKGVVLTHKSIVTSTAQVVDGENPNLYYKEEDVLLCLLPLFHIYAMHIVMLCALRRGCAMLLVERFEINKLLELIQRHRVSVAMVVPPLVLALAKNPAVAEYDLSSIRMVMCGAAPLGKDLEEALQNRLPQAVIAQAYGMTESGPVISMSMGFAKNAVMAPPKSGSCGSVVRNAEVKIVDIESGASLPYNMAGEICIRGQQIMKGYLHDEKATAAAIDAQGWLHTGDIGYVDSDHDIFIVDRLKEIIKFKGFQVPPAELEGILVSHPSIADAAVVPKEDDVAGEVPIAFVVRSSNGFDLTEHDVMDFIAKQVVFYKRIHGVYFINAIPKSQSGKISRKELKAKLAATN
>Ae09g00210.1
MAIDKETKQEIIFRSKLPDINIPKHLPLHSYCFENLSEYGSRPCLINAPTGQIYSYSDVQLTARKVASGLNKLGIQQGQVIMILLPNCPQFVFSFLGASFRGAIATAANPFFTPAEIAKQAKASNAKLLITQSSYYEKVKDLHSDDLKLMFVDSPPEGHLHFSELDQADEALIPDVKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYYHSEDVIMCVLPLFHIYSLNSVFLCGLRAKAAILLMPKFEIGAFLGLVHKHRVSICPVVPPIVLAIAKSPDLDKYDLSSIRVLKSGGAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLTMCLTFAKEPIDGKPGACGTVVRNAEMKIVDPDTDISLPRNQPGEICIRGDQIMKGYLNDVEATERTIDKEGWLHTGDIGYVDDDDELFIVDRLKELIKYKGFQVAPAELEALLLSHPNVSDAAVVPMKDEAAGEVPVAFVVKSNGKTDTTEDEIKQYISKQVVFYKRINRVFFVDVIPKSPSGKILRKDLRARLAAGVPN
>Ae10g14240.1
MSEGSEKLAEAIGNDSDAVRYMTMERKEELMIFRSRLPDIYIPKEVALHTFCFENNNSDLPCLINGPTGQVYSYSEVHLTARRVASSLNRLGVQQGHVIMLLLPNSPEFVFSFLGASHRGAITTAANPFFTPSEIANQARASNAKLLITQSCYYHKVKPLAHHLKLVFVDSLPPADANAQAESCYLHFSDLTKEEPSSTGAESCIVRAEEVVALPYSSGTTGVAKGVMLTHRGLVTSIAQQVDGDNPNLYYSSDDVVLCVLPLFHIYSLNSVLLCALRAKAAILLMPKFEIGAMLSLIERHRVTIAPVVPPILLAIATSHDLHNYDLSSIRVLKSGGAPLGEELEHTLRAKFPNVKLGQGYGMTEAGPVLTMSLAFAKEPVEVKPGSCGTVVRNAEMKIVDPETGKSLPRNHPGEICIRGDQIMKGYLNDREATERTIDKEGWLHTGDMGYVDDDDHVFIVDRLKELIKYKGFQVAPAEIEALLLSHPYISHAAVLPMKDEAAGEVPVAFVVRSNDVTEDEIKQFISKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRAKLPPGGGALQIDNQIKG
MEEEQPQQPTPSQDIIFRSKLPDIPIPTHLPLHSYCFQNLPQFHDRPCLIDAHTGATLTYSDVHLATLRIAAGLNTIGIQQGDVVMLLLRNCPDFALAFLGASRRGAAVTTANPFYTPAELAKQITATKTRLVITQSAYVEKIKDLAHEKNVMIMCIDSTEEQEKKDGVLNFSVLKNANEKEAPEVNIAPDDVVAIPFSSGTSGLPKGVMLTHRNLVTTVAQLVDGENPHQYTHGEDVLLCVLPMFHIYALNSILLCGIRAGAAVLIVEKFEMTALLEVVQRYRVTVASLVPPIVLALVKSGDAHRYDLSSIRAVITGAAPMGVDLQDAVKARLPHAVLGQGYGMTEAGPLAISLAFAKEAYKVKSGACGSVVRNAEMKIVDPDTGASLPRNKPGEVCIRGTKVMKGYLNDPEATERTIEKEGWLHTGDIGYMDDDDELFIVDRLKELIKYKGFQVPPAELEALLIAHPHISDAAVVPMKDEAAGEIPVAFVVKSNGSNITEDEIKQYISQQVVFYKRINRVFFTDTIPKAPSGKILRKVLTARVNQVLVAN
>Ae01g25790.1
MAPTKSDDDFIFRSKLPDIYIPTHLPLHTYCFENLSQFKHRPCLINATTGDTFSYAAVELTARKVAAGLNKLGIQQGDVILLLLQNCPQFVFAFLGASYRGATVTTANPFYTPAEVAKQATASNTKLIITQSSFIEKVKDLAIDSNVKIMCIDAPPPSNHGGYSYLHQFSELTEADEGEIPAVKISAEDVVALPYSSGTTGLPKGVMLTHKGLVTSVAQQVDGENPNLYLKSEDVILCVLPLFHIYSLNSVLLCGLRVGAAIVIMHKFEIVSLLEVVQKHKVSVAPFVPPIVLAIAKSPEVQRCDLSSIRMVMSGAAPMGKDLEDAVRAKLPNATLGQGYGMTEAGPVLCMSLAFAKEPFEVKSGACGTVVRNAQMKIVDPETGASLPRNHAGEICIRGNQIMKGYLNDREATEGTIDRERWLHTGDIGYVDGNDEVFIVDRLKELIKYKGFQVAPAELEAMLIAHPNISDAAVVAMKDEAAGEVPVAYVVRSNGSKTSEDEIKQYISKQVVFYKRINKVFFVDSIPKAPSGKILRKDLRARLAAGLAV
>Ae04g29520.1
MQKSGYGSDGIYRSLRPSITLPNNPKTSLTSFLFHQTSPFPSKPALIDATTSETLTFHHLKTTVTKLSHGLLRHGLTKNDVVLIFAPNSIHFPLFFLAATAIGAIVSTVNPLYTVSELSKQINDSNPKLLITTPELLEKVKSFKFDLPTVLLGSETTSSEFTTQSRLIELAPSTTELPVNDVNQNDTAALLYSSGTTGVSKGVILTHRNFIAASLSIGMDDDVAGDANDSIFLCVLPMFHVFALAVILYSQLRRGITMVSLGRFEFEAFLKAIEKFRVTDIWVVPPIVLALAKQSVVQNYDLSSLRRIGSGAAPLGKDLMKDCARRLPHLTLIQGYGMTETCGIISVENPRTGIRHSGSAGMLAASIDARIVSVDTQESLPPTQLGEILVRGANMMKGYYKNPEATKLTIDKQGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQIAPAELEGLLVSHPEILDAVVIPYPDDEAGEVPVACVVRSPNSSLTEEDVQKFIADQVAPYKRLRRVTFISAIPKTASGKILRRELIAKARSKM
>Ae04g36280.1
MLLPVEISHNLDTTSPKSSYHHKQKSQSTHIFKSKLPDIPLTNTIPLHTYCFQKLPQVADRPCLIAAATGKVYTYADTHLASRSFAAGLHTLGIQKGDVIMILLPNTPEFVFSFMATSMLGAVATTANPAYTSTEIMKQIKASKAKMVITQAMQVEKIKQEDDTFTVITVDDPPKNCMKFSAVCVDEKLLPEVDINPDDTVALPFSSGTTGLPKGVVLTHRSIVTSTIQVVDGENPNLYYKEEDVLLCLLPLFHIYAMHCVMLCALRRGSSVLLVERFEIKKLLELIQRHRVSVAMVVPPLVLALAKNPAVAEYDLSSIRMIMSGAASLGKDLEEALRARLPQAVIAQAYGMTESGPVISMSMAFAKNAVVAPKRGSCGSVVRNAELKIVDIQSGASLPYCKAGEICIRGQQIMKGYLDDEKATAAAVDAEGWLHTGDIGYVDYDHDIFIVDRLKEIIKFKGFQVPPAELEGILVSHPSIADAAVVPKEDDVTGEVPVAFVVRSSNGFDLTEHDVKEFIAKQVVFYKRLHGVYFINAIPKSPSGKISRKELKAKLAATS
>Ae05g11160.1
MLSVAPSVDSAKQSTELSSSPKDAIPPPTEQKQPSPQTTHIFKSRLPDIPISNHLPLHTYCFERLSEFSDRPCLIVGSAAKTYTYAETYLASQKIAAGLSSLGIKKGDVIMILLQNSAEFVLSFIAASMIGAVATTANPFYTSAEIFKQIAASKSKLVITMAMYVDKLREQDAVNSLKLGEDFKVITVDDPPENCLHFSVISEGNENEVPEVEIRPEDAVALPFSSGTTGLPKGVVLTHKSLTTSVAQQVDGENPNLYLKAEDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMQKFEIGALLELIQKYKVSVAMVVPPLVLALAKNPMVAGYDLSSIRLVLSGAAPLGKELEEALRSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAELKVIDPETGFSLGYNQPGEICIRGQQIMKGYLNDDKATATTIDIEGWLHTGDVGYIDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVAAGEVPVAFVVRSNGFDLTEEAVKDFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLENNTTQTL
>Ae06g29720.1
MGTNIENIVQGEDEHIFHSQFEPVPVPDDVTLPEFVLQQAELYADKVAFVDAVTEKKITYSEVVRDTQRFSKALRSIGVRKGHVVIVVLPNVVEYGIIALGIMGAGGVFSGANPASHASEIKKQADSADAKLIVTNDTHYEKVKGLELPVIVLSDERVGGAMNWKKLLEAADRAGSDDFKKEQIHQNDLCAMPFSSGTTGLSKGVMLTHRNLVANLCSTLFGVGKEMIGQVTTLGLIPFFHIYGITGICCATLKSKGKVVVMGRFELKTFLNALITHEVTFAPIVPPIILSLVKNPIVNEFDLTKLKLQAIMTAAAPLAPELLTAFEHKFPGVIVQEAYGLTEHSCITLTHAQKSSAILHKTSVGFILPNLEVKFIDPDTGRSLPRNTHGELCVRSQCVMQGYYKQVDETTQTIDKNGWLHTGDIGFIDDEENIFIVDRIKELIKYKGFQVAPAELEAILLSHPSVEDAAVVPLPDEEAGEIPAASVVLSKGANESEEDIMNHVASNAAHYKKVRVVHFVEAIPKSPSGKIMRRLIKDRMVEKIKAKSTNKSNSS
>Ae06g16470.1
MLLPVEISHNLDTQLKSTSPKTSHHHKQKSQTTHIFKSKLPDIPLTNTIPLHTYCFQKLPQVADRPCLITAATGKVYTYADTHLASRSFAAGLHNLGIRKGDVIMILLPNTPEFVFSFMAASMLGAAATTANPAYTSTEIMKQIKASKAKMVITQAMQVEKVKEKQEEDDTFVVITVDDPPAENCMKFSAVCVDEELPEVDIDPDDTVALPFSSGTTGLPKGVVLTHKSIVTSTAQVVDGENPNLYYKEEDVLLCLLPLFHIYAMHIVMLCALRRGCAMLLVERFEINKLLELIQRHRVSVAMVVPPLVLALAKNPAVAEYDLSSIRMVMCGAAPLGKDLEEALQNRLPQAVIAQAYGMTESGPVISMSMGFAKNAVMAPPKSGSCGSVVRNAEVKIVDIESGASLPYNMAGEICIRGQQIMKGYLHDEKATAAAIDAQGWLHTGDIGYVDSDHDIFIVDRLKEIIKFKGFQVPPAELEGILVSHPSIADAAVVPKEDDVAGEVPIAFVVRSSNGFDLTEHDVMDFIAKQVVFYKRIHGVYFINAIPKSQSGKISRKELKAKLAATN
>Ae09g00210.1
MAIDKETKQEIIFRSKLPDINIPKHLPLHSYCFENLSEYGSRPCLINAPTGQIYSYSDVQLTARKVASGLNKLGIQQGQVIMILLPNCPQFVFSFLGASFRGAIATAANPFFTPAEIAKQAKASNAKLLITQSSYYEKVKDLHSDDLKLMFVDSPPEGHLHFSELDQADEALIPDVKISPDDVVALPYSSGTTGLPKGVMLTHKGLVTSVSQQVDGENPNLYYHSEDVIMCVLPLFHIYSLNSVFLCGLRAKAAILLMPKFEIGAFLGLVHKHRVSICPVVPPIVLAIAKSPDLDKYDLSSIRVLKSGGAPLGKELEDTVRAKFPNAKLGQGYGMTEAGPVLTMCLTFAKEPIDGKPGACGTVVRNAEMKIVDPDTDISLPRNQPGEICIRGDQIMKGYLNDVEATERTIDKEGWLHTGDIGYVDDDDELFIVDRLKELIKYKGFQVAPAELEALLLSHPNVSDAAVVPMKDEAAGEVPVAFVVKSNGKTDTTEDEIKQYISKQVVFYKRINRVFFVDVIPKSPSGKILRKDLRARLAAGVPN
>Ae10g14240.1
MSEGSEKLAEAIGNDSDAVRYMTMERKEELMIFRSRLPDIYIPKEVALHTFCFENNNSDLPCLINGPTGQVYSYSEVHLTARRVASSLNRLGVQQGHVIMLLLPNSPEFVFSFLGASHRGAITTAANPFFTPSEIANQARASNAKLLITQSCYYHKVKPLAHHLKLVFVDSLPPADANAQAESCYLHFSDLTKEEPSSTGAESCIVRAEEVVALPYSSGTTGVAKGVMLTHRGLVTSIAQQVDGDNPNLYYSSDDVVLCVLPLFHIYSLNSVLLCALRAKAAILLMPKFEIGAMLSLIERHRVTIAPVVPPILLAIATSHDLHNYDLSSIRVLKSGGAPLGEELEHTLRAKFPNVKLGQGYGMTEAGPVLTMSLAFAKEPVEVKPGSCGTVVRNAEMKIVDPETGKSLPRNHPGEICIRGDQIMKGYLNDREATERTIDKEGWLHTGDMGYVDDDDHVFIVDRLKELIKYKGFQVAPAEIEALLLSHPYISHAAVLPMKDEAAGEVPVAFVVRSNDVTEDEIKQFISKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRAKLPPGGGALQIDNQIKG
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University