Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Cicer arietinum
Species name
Chickpea (Cicer arietinum) is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Cicer_arietinum.OMT.fa
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>rna-XM_004490629.3
MESQNGEHVASNLLKAQSHIWNHIFNFINSMSLKCVVDLGIPDIIHNYGKPISLSKLIPLLPIHPSKTIFIYRLMRIMTHSGFFSQQNITENELETEYMLTDTSLLLLSDNPMSVAPFVHAMLDPVLTNPWHQLSTWLTNGDPTAFETKHGMLFWDCAEREPKFNNLFNDAMASDARLVSSVVIEKCKEVFNGLESIVDVGGGIGTMAKALAKSFPQLECTVLDLPHVVAGLQETENLKYVGGDMFKEIPSADAILLKWILHDWNDDECVKILKNCKDAIAKKGKEGKVIIIDMVMENEKGKNESLQTQLFFDMLMMVLVTGKERTKKEWVNLISSSGFSNYKITPILGLRSVIEIYP
>rna-XM_004489471.3
MSNSLINGHNPREIFQAQALLYKHIFAFIDSMCLKWTVEMNIPNIIHNHNKPITLSNLVSILQVPSSKIGNVQRLMRYLAHNGFFEIITNQEEENEESYALTVASKLLVKGSDLCLAPMVECVLDPTLSGSYHQLKKWIYEEDLTLFGVTLGSGFWDFLNKNPEYNKSFNEAMASDSKMINLALRDCNLVFEGLESMVDVGGGTGTTAKIICDTFPKLKCVVFDRPQVVDNLCGSNNLSYVGGDMFSSVPNADAVLLKWILHNWTDKDCIRILEKCKEAVTSNGKKGKVIVIDMVINEKKDENQITQIKLLMDVNMACLNGKERNEKEWKKLFIEAGFQDYKISPLTGFLSLMEIYP
>rna-XM_004490639.3
MESQNGEHDASNLLKAQSHIWNHIFNFINSMSLKCVVDLGIPDIIHNYGKPMSLSKLIPLLPIHPSKTFFIYRLMRIMTHSGFFSQHNISENELETEYVLTDTSLLLLKDNPMNMRSFVHLVFDPVLTKPWHQLSSWLTNDDPTAFETTHGMLFWDYAERESKINNLFNDAMASDARLVSSVVIEKCKEVFNGLESLVDVGGGTGTMAKALAKSFPQLECTVFDLPHVVVGLQGTDNLKYVGGDMFKEIPPADAILLKWILHDWNDDECVKILKKCKESLLKKGNEGKVIIIDMVLDTKKGDINESGKTQLFFDMLMTVLVKGKERNDKEWIKLISLAGFSDYKIIPILGLRSLIEVYP
>rna-XM_004490630.3
MESHNASNLLKAQSHIWNHMCNFINSMSLKCVVDLGIPDIIHNYEKPMPLSVLISSLPIHPSKIPCIYRLMRIMTHLGFFSKDNVTENELEIEYMLTDESILLLKDHPMSVTPFLQVVLDPIVANPWHNLSTWLKNDDPTTFETTHGMLIWDYAAREPKFNNLFNDAMASDARLVTSVVIEKCKGVFNGLESLVDVGGGTGTMAKALAKTFPMMECNVFDLPHVVDGLQGSDNLNYVGGDMFKNIPPADAILLKWILHDWNDDECVKILKNCKDAIAKKGKKGKVIIIDMVMEKEKGNNETLGTQLFFDMLMMVLATGKERTKKEWVNLISSSGFSDYKITPVLGLRSVIEIYP
>rna-XM_012716351.2
MGEVQREIITWEKEEEEKEEEEAQVEIWKYIFGFVELAVVKCAIQLGIAEAIENHKKPMSLLEISSTLNCDPSYLNRIMRFLTHRKIFKTIPSDHNDNPSYVQTPLSRRLISNSEKSMSALLLLESSHVMVAPWLSLSERVLVNGNPSFEKVNGEDIWRFAATNLDHSNLINDAMACDARVVVPAIVEGCSEVFDGVNSLVDVGGGNGTTISILAKAFPRIQRLINFDLPHVIVVAPKCDRVEHVAGDMFTSVPKADVAFVKWVLHDWSDEECINILKRXXXXREAIPKENGKVIIVEAVIEEGEKNKNKYKDVGLMLDMVMMAHTNFGKERTMKEWEYVIKMAGFNSFNVKSINAVQCVIVASC
>rna-XM_004505050.3
MDFNSNGSEENELYRAQIHLYKHVYNFVSSMALKSVMELGIADVIDNHGKPMTLNELATSLKLHPSKVNILHRFLRLLTYNGFFVKTTVNAKEGGEGEIAYSLTPPSKLLVSGKSTCLAPIVKGALHPSSLDMWSASKQWFNEDKEQTLFESATGESFWDFLNKQSDTLSMFQDAMASDSRMFELALQENKHVFEGLESLVDVGGGTGGVTKLINKAFPHLKCTVFDQPQVVGNLTGTENLNFVGGDMFKSIPPADAVLLKWVLHDWNDEQSLKILKNSKEAISGKGKDGKVIIIDISIDETSDDRELTGLQLDYDLVMLTMFLGKEREKKEWEKLIYDAGFSSYKIRTISGFKSIIEVFP
>rna-XM_012717202.2
IESSSTRFLQAKPMAQSEEHATKLLQAQTQVFNQIFSFINSMSLKCAIELSIPDIIHNYGQPIPLSQLISSLPIHPSKSGDIDRLMRVLTHSNFFIVTKNELEVMYELTDASRLLLKDHPFSMTSMLHVILGPIMSKPWHQLSNWYKNEDPSPFYTENNGIEFWDYAGHDPEFNHLFNEAMACETRMASTVVMGKCKGVFQGLESLVDVGGGIGTMSKAIAKSFPNIECIVFDLPHVVDGLQGSENFKYVAGDMFESIPPTQSILLKGVLHDWNDEECLKILKKCKEAIKSKGKEGKVIIIDAVMGNEKADNESFEAQLFYDLEMMVLVNGKERNEKEWSKLFFSAGFNNYKITHGLGFKSLIEVFP
>rna-XM_004505048.3
MDFSSNESEESELYHAQIHLYKHLYSFISSAALKSAVELGIADAIHNHGKPMTLNELASSLKLHPSKVNILYRFLRLLTHNGFFVKTTVMKGEEEETAYSLTPPSKLLISGKQTCLSSMVKGTLQPMPLDMWHSSNKWFNEEKEQTLFESATGENFWNFLNKDSESDKLNMFQDAMAADSQIFKIALKDCKHVFEGVESLVDVGGGTGAVTKLINEAFPNIKCTVFDQPQVVGNLTGTQNLNFVGGDMFKSIPPADAVLLKWVLHDWDDEQSLKILKNSKEAISGKGKGGKVIIIDISIDEISDNRIITELQLDFDFMMMTLFNGKEREKKEWEKLIFNAGFSSYKITPICSFKSLIEVYP
>rna-XM_012717470.2
METVLSKHSPPSAFKGLSKEEEESLLGQIEIWKYMTQFTDSFALKSVVELRIADIIDRYGKPLSLTQIVQNLDDAPSPDSTLLLRIMRVMVRRKIFSSEKSETGETLYGLTRASKWILQDTKMTLAPMLLLENHPFHLNPANFISDIIREGTKNGTAFFRCHGHEQFEMTGLDPKYNELFNQGMVCTARIVSRAVIAGYKDGFNQIQSLVDVGGGIGGSLSEIVRAYPHIQGINFDLPHVVETAPKFDGITHVGGDMFVSVPSADAIYMKWILHDWSDDHCIKILKNCRKAIPEKTGKVIIVDHVLDPEGDEPFTDTGIAFDMMLLAHNAGGKERTEENWKYLFKETGFPRYNIIKINALPSIIEAFPI
>rna-XM_004505335.3
MGSENVYKSNELFEAQTHLYNHILSFLKPMSIKWAVELGIPDIIHNHGQPITLPQLLSVLQIHEDKSSLVKSLMRLLAHNNFFRIVKTEGKEAYALSPPSELLVKDTDHCLSSMVNLLTNPNVVNLYNHLGKWTFGEKSSIFENTSDTGDYWGFVHQNPKSLKSFNEAMESDSHVVRLALKDCKSIFESLDCLVDVGGGTGNTAKIICETFPMLKCTVLDLPQVIAGLPTNNKNLSFVGGDMFESIPEADAVLLKWILHDWNDDDCVKILQNCKKAVSRKGKGGKVVIIDIVINEKQDKHEMTEVKLFFDIVMMASFNGKERDGKNWNEIIMKAGFTRYKIFPIFGFRSLIEVYV
>rna-XM_004505049.3
MDFSTNENEENELYHAQIHLYKHLYSFISSMALKSAMELGISDAIYNHGKPMTLPELASALKLHPSKVNILYRLLRLLTHNGFYAKTTVMKGEEEEEKTAYALTPPSKLLIRGKSTCLAPMVQGSLNPLALDMWHSSKKWFNEDKELELFESATGDNFWDVLNEDSDKLSLFQDAMAADSQMFKIALKDCKHVFEGVDSLVDVGGGTGGVTKLINEAFPNIKCTVFDQPQVVGNLIGNENLNFVGGDMFNSIPPADAVLLKWVLHDWNDELSLKILKNSKEAISGKGKKGKVIIVDISIDETSDDRELTELQLHFDMVMLTLHNGKEREKKEWEKLIYDAGFNSYKITPVFGFKSLIEVFP
MESQNGEHVASNLLKAQSHIWNHIFNFINSMSLKCVVDLGIPDIIHNYGKPISLSKLIPLLPIHPSKTIFIYRLMRIMTHSGFFSQQNITENELETEYMLTDTSLLLLSDNPMSVAPFVHAMLDPVLTNPWHQLSTWLTNGDPTAFETKHGMLFWDCAEREPKFNNLFNDAMASDARLVSSVVIEKCKEVFNGLESIVDVGGGIGTMAKALAKSFPQLECTVLDLPHVVAGLQETENLKYVGGDMFKEIPSADAILLKWILHDWNDDECVKILKNCKDAIAKKGKEGKVIIIDMVMENEKGKNESLQTQLFFDMLMMVLVTGKERTKKEWVNLISSSGFSNYKITPILGLRSVIEIYP
>rna-XM_004489471.3
MSNSLINGHNPREIFQAQALLYKHIFAFIDSMCLKWTVEMNIPNIIHNHNKPITLSNLVSILQVPSSKIGNVQRLMRYLAHNGFFEIITNQEEENEESYALTVASKLLVKGSDLCLAPMVECVLDPTLSGSYHQLKKWIYEEDLTLFGVTLGSGFWDFLNKNPEYNKSFNEAMASDSKMINLALRDCNLVFEGLESMVDVGGGTGTTAKIICDTFPKLKCVVFDRPQVVDNLCGSNNLSYVGGDMFSSVPNADAVLLKWILHNWTDKDCIRILEKCKEAVTSNGKKGKVIVIDMVINEKKDENQITQIKLLMDVNMACLNGKERNEKEWKKLFIEAGFQDYKISPLTGFLSLMEIYP
>rna-XM_004490639.3
MESQNGEHDASNLLKAQSHIWNHIFNFINSMSLKCVVDLGIPDIIHNYGKPMSLSKLIPLLPIHPSKTFFIYRLMRIMTHSGFFSQHNISENELETEYVLTDTSLLLLKDNPMNMRSFVHLVFDPVLTKPWHQLSSWLTNDDPTAFETTHGMLFWDYAERESKINNLFNDAMASDARLVSSVVIEKCKEVFNGLESLVDVGGGTGTMAKALAKSFPQLECTVFDLPHVVVGLQGTDNLKYVGGDMFKEIPPADAILLKWILHDWNDDECVKILKKCKESLLKKGNEGKVIIIDMVLDTKKGDINESGKTQLFFDMLMTVLVKGKERNDKEWIKLISLAGFSDYKIIPILGLRSLIEVYP
>rna-XM_004490630.3
MESHNASNLLKAQSHIWNHMCNFINSMSLKCVVDLGIPDIIHNYEKPMPLSVLISSLPIHPSKIPCIYRLMRIMTHLGFFSKDNVTENELEIEYMLTDESILLLKDHPMSVTPFLQVVLDPIVANPWHNLSTWLKNDDPTTFETTHGMLIWDYAAREPKFNNLFNDAMASDARLVTSVVIEKCKGVFNGLESLVDVGGGTGTMAKALAKTFPMMECNVFDLPHVVDGLQGSDNLNYVGGDMFKNIPPADAILLKWILHDWNDDECVKILKNCKDAIAKKGKKGKVIIIDMVMEKEKGNNETLGTQLFFDMLMMVLATGKERTKKEWVNLISSSGFSDYKITPVLGLRSVIEIYP
>rna-XM_012716351.2
MGEVQREIITWEKEEEEKEEEEAQVEIWKYIFGFVELAVVKCAIQLGIAEAIENHKKPMSLLEISSTLNCDPSYLNRIMRFLTHRKIFKTIPSDHNDNPSYVQTPLSRRLISNSEKSMSALLLLESSHVMVAPWLSLSERVLVNGNPSFEKVNGEDIWRFAATNLDHSNLINDAMACDARVVVPAIVEGCSEVFDGVNSLVDVGGGNGTTISILAKAFPRIQRLINFDLPHVIVVAPKCDRVEHVAGDMFTSVPKADVAFVKWVLHDWSDEECINILKRXXXXREAIPKENGKVIIVEAVIEEGEKNKNKYKDVGLMLDMVMMAHTNFGKERTMKEWEYVIKMAGFNSFNVKSINAVQCVIVASC
>rna-XM_004505050.3
MDFNSNGSEENELYRAQIHLYKHVYNFVSSMALKSVMELGIADVIDNHGKPMTLNELATSLKLHPSKVNILHRFLRLLTYNGFFVKTTVNAKEGGEGEIAYSLTPPSKLLVSGKSTCLAPIVKGALHPSSLDMWSASKQWFNEDKEQTLFESATGESFWDFLNKQSDTLSMFQDAMASDSRMFELALQENKHVFEGLESLVDVGGGTGGVTKLINKAFPHLKCTVFDQPQVVGNLTGTENLNFVGGDMFKSIPPADAVLLKWVLHDWNDEQSLKILKNSKEAISGKGKDGKVIIIDISIDETSDDRELTGLQLDYDLVMLTMFLGKEREKKEWEKLIYDAGFSSYKIRTISGFKSIIEVFP
>rna-XM_012717202.2
IESSSTRFLQAKPMAQSEEHATKLLQAQTQVFNQIFSFINSMSLKCAIELSIPDIIHNYGQPIPLSQLISSLPIHPSKSGDIDRLMRVLTHSNFFIVTKNELEVMYELTDASRLLLKDHPFSMTSMLHVILGPIMSKPWHQLSNWYKNEDPSPFYTENNGIEFWDYAGHDPEFNHLFNEAMACETRMASTVVMGKCKGVFQGLESLVDVGGGIGTMSKAIAKSFPNIECIVFDLPHVVDGLQGSENFKYVAGDMFESIPPTQSILLKGVLHDWNDEECLKILKKCKEAIKSKGKEGKVIIIDAVMGNEKADNESFEAQLFYDLEMMVLVNGKERNEKEWSKLFFSAGFNNYKITHGLGFKSLIEVFP
>rna-XM_004505048.3
MDFSSNESEESELYHAQIHLYKHLYSFISSAALKSAVELGIADAIHNHGKPMTLNELASSLKLHPSKVNILYRFLRLLTHNGFFVKTTVMKGEEEETAYSLTPPSKLLISGKQTCLSSMVKGTLQPMPLDMWHSSNKWFNEEKEQTLFESATGENFWNFLNKDSESDKLNMFQDAMAADSQIFKIALKDCKHVFEGVESLVDVGGGTGAVTKLINEAFPNIKCTVFDQPQVVGNLTGTQNLNFVGGDMFKSIPPADAVLLKWVLHDWDDEQSLKILKNSKEAISGKGKGGKVIIIDISIDEISDNRIITELQLDFDFMMMTLFNGKEREKKEWEKLIFNAGFSSYKITPICSFKSLIEVYP
>rna-XM_012717470.2
METVLSKHSPPSAFKGLSKEEEESLLGQIEIWKYMTQFTDSFALKSVVELRIADIIDRYGKPLSLTQIVQNLDDAPSPDSTLLLRIMRVMVRRKIFSSEKSETGETLYGLTRASKWILQDTKMTLAPMLLLENHPFHLNPANFISDIIREGTKNGTAFFRCHGHEQFEMTGLDPKYNELFNQGMVCTARIVSRAVIAGYKDGFNQIQSLVDVGGGIGGSLSEIVRAYPHIQGINFDLPHVVETAPKFDGITHVGGDMFVSVPSADAIYMKWILHDWSDDHCIKILKNCRKAIPEKTGKVIIVDHVLDPEGDEPFTDTGIAFDMMLLAHNAGGKERTEENWKYLFKETGFPRYNIIKINALPSIIEAFPI
>rna-XM_004505335.3
MGSENVYKSNELFEAQTHLYNHILSFLKPMSIKWAVELGIPDIIHNHGQPITLPQLLSVLQIHEDKSSLVKSLMRLLAHNNFFRIVKTEGKEAYALSPPSELLVKDTDHCLSSMVNLLTNPNVVNLYNHLGKWTFGEKSSIFENTSDTGDYWGFVHQNPKSLKSFNEAMESDSHVVRLALKDCKSIFESLDCLVDVGGGTGNTAKIICETFPMLKCTVLDLPQVIAGLPTNNKNLSFVGGDMFESIPEADAVLLKWILHDWNDDDCVKILQNCKKAVSRKGKGGKVVIIDIVINEKQDKHEMTEVKLFFDIVMMASFNGKERDGKNWNEIIMKAGFTRYKIFPIFGFRSLIEVYV
>rna-XM_004505049.3
MDFSTNENEENELYHAQIHLYKHLYSFISSMALKSAMELGISDAIYNHGKPMTLPELASALKLHPSKVNILYRLLRLLTHNGFYAKTTVMKGEEEEEKTAYALTPPSKLLIRGKSTCLAPMVQGSLNPLALDMWHSSKKWFNEDKELELFESATGDNFWDVLNEDSDKLSLFQDAMAADSQMFKIALKDCKHVFEGVDSLVDVGGGTGGVTKLINEAFPNIKCTVFDQPQVVGNLIGNENLNFVGGDMFNSIPPADAVLLKWVLHDWNDELSLKILKNSKEAISGKGKKGKVIIVDISIDETSDDRELTELQLHFDMVMLTLHNGKEREKKEWEKLIYDAGFNSYKITPVFGFKSLIEVFP
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University