Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Cicer arietinum
Species name
Chickpea (Cicer arietinum) is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Cicer_arietinum.4CL.fa
Download
>rna-XM_004487010.3
MQRSGYGSDGIYRSLRPSLTLPKHPNLSLVTHLFTKVASSLTKPALIDADSLQTLTFAQLKSLTIKLSHALIHIGVTKNDVVLFLAPNSYLYPVFFLAVASIGAVASTVNPAYTIAEVSKQANDSKPKLIITVAELYSKVKHLNLPAVFLDSTDILQNSNVTSYKSLIKLGDSATEFPKVDVKQTDTAALLYSSGTTGMSKGVILTHGNFIASSLMIGMDDELAGDKDDVFLVVLPMFHVFGLAVITYSQLQRGNAVVSLKKFEFEVVLKTVEKYRVTRLWVVPPIVLALAKHALVDKYDLSSLKYIGSGAAPLGKELMEECAKRFPHTIVAQGYGMTETSGIVSVENTRMGVRHTGSAGMXXXXXEAQIVSVDTLKPLPPGQLGEIWVRGPNMMQGYHNNPQATSLTIDKSGWVHTGDLGYFDEDGHLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEKDVQKFIADQVAPFKRLRKVTFISTVPKTASGKILRRELIDKVRSKI
>rna-XM_004486536.3
MALEEEKEIIFRSKLPDIYIPNHLPLHCYCFENLSEYGSRTCLINAPTGTHYTYSDVQLTSRRVASGLHNLGVQQGDVIMILLPNSPEFVFSFLAASYLGAIATAANPFFTAAEIGKQVKASNAKLLITQACYYQKVKALLKVESEDDDVINNNNNNKKKKKKVVLVDSLSNVDDDDDDDDVEVHYFSSVSEGDENEVGEVKIEGDDVVALPYSSGTTGLPKGVMLTHKGLVSSIAQQVDGENPNLYYTCDDVILCVLPLFHIYSLNSVLLCGLRAKSTILLMPKFEINAFLTLVHKHRVTVAPVVPPIVLAIAKSPDLQNYDLSSIRILKSGGAPLGKELEHTVRAKFPNAILGQGYGMTEAGPVLTMSLAFAKEAVNVKAGACGTVVRNAEMKIVDPETGHSLPRNQSGEICIRGHQIMKGYLNDREATERTIDKEGWLHTGDIGYIDEDDELFIVDRLKELIKYKGFQVAPAELEALLLSHPKISDAAVVPMKDEAAGEVPVAFVVRSNGYTDLTEDQIKQFISKQVVFYKRINQVFFIDAIPKSPSGKILRKDLRAKLAAPLPN
>rna-XM_004497481.3
MANKNSLFDLKTMTYSSPRPPIHLPTDPNLSLTTFLFQSTSSAADSIALADAHSNDSLTFHQLKTQVIALSHSLLRLGIKRGDIVLLFAPNSIRFPVCFLAVVAIGAIATTCSPLYTPSELSKQINDSKPKLVITVSELYQKIKALKLDLPSILLEDPSSSVISSNKFGSKVLYYDNLIEESIESSGEIPATGAVLQSDVAALLYSSGTTGRSKGVMLTHRNFIAVAVAGSADQDRYGDGKNVFLCLVPMHHVMGLAVITYTQLRRGNTVVSMGRFELEKALAAVEKFRVTHLYVAPPVMVELNKRRQVLSGYDLSSLKQLAGGAAPLGKDVMQECAKILPQVEIIQGYGMTEASGLISVENPKESCFIAVSGSTGTLIPCIESQIVSLETSKPLPPNQLGEIWLRGPTIMKGYFNNPEATKLTIDDKGWMLTGDLGYFDEKGQLFVVDRIKELIKCSGYQVAPAELEDLLVSHPEISDAGVIPSPDAKAGEVPVAFVVRSPDSSITEEEIQKFVAKQVAPYKRLRRVSFIDKIPKSPTGKILRKDLIIFDRQKTSKL
>rna-XM_004507487.3
MTIKKENKEMNQQKIEEFIFKSKLPNIYIPKHLPLHSYCFENLSKYGSLPCLINAPTGEIYTYYDVELTARRVASGLDKFGVRQGDVIMLLLPNCPEFVFSFLGASFRGAITTTANPFFTSAEIAKQAKGSNAKLLVTQVCYYDKVKDLDHLKLVFIDSELDSTLENHIHFRDLAQADENEMKEVNIKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYYHKEDVILCVLPMFHIYSLNSVLLCGLRAKAAILLMPKFDINAFLSHVNKYKVTIAPVVPPIVLAIAKSPDLHKYDLSSIRVLKSGGAPLGKELEDSVRAKFPKAKLGQGYGMTEAGPVLTMCLSFAKEPIDVKAGACGTVVRNAEMKIVDPENDSSLPRNQPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAIILSHPQIYDVAVVPMKDEAAGEVPVAFVVKSNSQINTTEDEIKQFVSKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRAKLAAGVPN
>rna-XM_004507784.3
MSPSPPQQEEEFIFRSKLPDIQIPTHLPLHSYCFQNLSQFHNRPCLINGDTGETLTYSDVHLTVRKIAAGLNSTLGINQGDVIMLVLRNSHQFALTFLGASYRGAVVTTANPFYTSSELAKQATATKTKLIVTQSAYINKINEFAKINKIKIVCTDSSPASSSDEESVVHFSVLTNADEKDAPEVKISPNDVVALPFSSGTSGLPKGVMLTHENLVTTIAQLVDGENPHQYTKYEDVLLCVLPMFHIYALNSILLSGIRSGAAVLIVEKFEITTLLELIDKYKVTVVSFVPPIVLALVKSGESNRYDLSCIRAMITGAAPMGVELEQAVKDRLPQAILGQGYGMTEAGPLSISMSFAKEAMGTKPGACGTVVRNAEMKIVDTETGHSLPRNKPGEICIRGTKVMKGYLNDPEATKRTIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGYQVAPAELEALLISHPNISDAAVVPLKDEAAGEVPVAFVVRSNGSKITEDEIKQYISKQVVFYKRINIVFFVDTIPKAASGKILRKELTARLNEGLVVAT
>rna-XM_004511366.3
MLSVAPSVDAKQTTEVSASVTKLNTQQQEPTDFNHNHNHDRDDNTNSIISSQNNLIFKSKLPDIPLSNHLPLHTYCFEKLPEITDRPCLIVASTGKIYTYGEAHLLSRKIAAGMSKLGIQKGDVIMILLQNSAEFVLSFIAASMIGAVATTANPFYTAAELFKQLTVCKTKLIITQAMYVDKLKQNEENGEFDFKIITVDEPPVNCLHFSVISEGNEEELLEVEIDPEDAVALPFSSGTTGLPKGVILTHKSLTTSVAQQVDGENPNLYLTTEDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMHKFEIGTLLDVIQKHRVTVAMVVPPLVLALAKNPSVAEFDLSSIRLVLSGAAPLGKELEEALHNRIPQAVLGQGYGMTEAGPVLSMSLSFAKQPLPTKSGSCGTVVRNAELKVLDPETGHSLGYNQPGEICIRGQQIMKGYLNDENATKTTIDEEGWLHTGDVGYIDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVAAGEVPVAFVVRSNGFDLTEEAVKEFISKQVVFYKRLHKVYFIHAIPKSPAGKILRKDLRAKLENATQTI
>rna-XM_004516041.2
MGTYIENFVEEKEHIFRSQYSPVPVPDNVTLPEFVLQNVELYGDKVAFVDAESGKCVTYSEVERDIHRFSKALRSLGLRKGNVVIVVLPNIVEYAIVALGIMDSGGVFSGANPTLHASEIKKQAESADAKLIVTNSVTHEKVKNLGLPIIVLGDELIEDAMNWNKLLEAADRAGDDSMKEQIHQNDLCAMPFSSGTTGLSKGVMLTHRNLVANLCSTLFGVAQEMIGQVTTLGLIPFFHIYGITGICCATIRNKGKVVVMGRFDLKTFLNALITHEVTFAPIVPPIILGLVKNPIVDEFDLTKLKLQAIMTAAAPLAPEILTSFEHKFPGVLVQEAYGLTEHSCITLTHAQKGYGNTHKNSVGFILPNLEVKFIDPDTGRSLPRNTPGELCVRSQCVMQGYYKQVDETAQTIDNNGWLHTGDVGFIDDEENVFIVDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPNEEAGEIPAASVVLSIGAKESEQDIMNYVASNAAHYKKVRVVHFVEAIPKSPSGKIMRRLIKEKMVEKMKENSLTKSNTSSN
MQRSGYGSDGIYRSLRPSLTLPKHPNLSLVTHLFTKVASSLTKPALIDADSLQTLTFAQLKSLTIKLSHALIHIGVTKNDVVLFLAPNSYLYPVFFLAVASIGAVASTVNPAYTIAEVSKQANDSKPKLIITVAELYSKVKHLNLPAVFLDSTDILQNSNVTSYKSLIKLGDSATEFPKVDVKQTDTAALLYSSGTTGMSKGVILTHGNFIASSLMIGMDDELAGDKDDVFLVVLPMFHVFGLAVITYSQLQRGNAVVSLKKFEFEVVLKTVEKYRVTRLWVVPPIVLALAKHALVDKYDLSSLKYIGSGAAPLGKELMEECAKRFPHTIVAQGYGMTETSGIVSVENTRMGVRHTGSAGMXXXXXEAQIVSVDTLKPLPPGQLGEIWVRGPNMMQGYHNNPQATSLTIDKSGWVHTGDLGYFDEDGHLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEKDVQKFIADQVAPFKRLRKVTFISTVPKTASGKILRRELIDKVRSKI
>rna-XM_004486536.3
MALEEEKEIIFRSKLPDIYIPNHLPLHCYCFENLSEYGSRTCLINAPTGTHYTYSDVQLTSRRVASGLHNLGVQQGDVIMILLPNSPEFVFSFLAASYLGAIATAANPFFTAAEIGKQVKASNAKLLITQACYYQKVKALLKVESEDDDVINNNNNNKKKKKKVVLVDSLSNVDDDDDDDDVEVHYFSSVSEGDENEVGEVKIEGDDVVALPYSSGTTGLPKGVMLTHKGLVSSIAQQVDGENPNLYYTCDDVILCVLPLFHIYSLNSVLLCGLRAKSTILLMPKFEINAFLTLVHKHRVTVAPVVPPIVLAIAKSPDLQNYDLSSIRILKSGGAPLGKELEHTVRAKFPNAILGQGYGMTEAGPVLTMSLAFAKEAVNVKAGACGTVVRNAEMKIVDPETGHSLPRNQSGEICIRGHQIMKGYLNDREATERTIDKEGWLHTGDIGYIDEDDELFIVDRLKELIKYKGFQVAPAELEALLLSHPKISDAAVVPMKDEAAGEVPVAFVVRSNGYTDLTEDQIKQFISKQVVFYKRINQVFFIDAIPKSPSGKILRKDLRAKLAAPLPN
>rna-XM_004497481.3
MANKNSLFDLKTMTYSSPRPPIHLPTDPNLSLTTFLFQSTSSAADSIALADAHSNDSLTFHQLKTQVIALSHSLLRLGIKRGDIVLLFAPNSIRFPVCFLAVVAIGAIATTCSPLYTPSELSKQINDSKPKLVITVSELYQKIKALKLDLPSILLEDPSSSVISSNKFGSKVLYYDNLIEESIESSGEIPATGAVLQSDVAALLYSSGTTGRSKGVMLTHRNFIAVAVAGSADQDRYGDGKNVFLCLVPMHHVMGLAVITYTQLRRGNTVVSMGRFELEKALAAVEKFRVTHLYVAPPVMVELNKRRQVLSGYDLSSLKQLAGGAAPLGKDVMQECAKILPQVEIIQGYGMTEASGLISVENPKESCFIAVSGSTGTLIPCIESQIVSLETSKPLPPNQLGEIWLRGPTIMKGYFNNPEATKLTIDDKGWMLTGDLGYFDEKGQLFVVDRIKELIKCSGYQVAPAELEDLLVSHPEISDAGVIPSPDAKAGEVPVAFVVRSPDSSITEEEIQKFVAKQVAPYKRLRRVSFIDKIPKSPTGKILRKDLIIFDRQKTSKL
>rna-XM_004507487.3
MTIKKENKEMNQQKIEEFIFKSKLPNIYIPKHLPLHSYCFENLSKYGSLPCLINAPTGEIYTYYDVELTARRVASGLDKFGVRQGDVIMLLLPNCPEFVFSFLGASFRGAITTTANPFFTSAEIAKQAKGSNAKLLVTQVCYYDKVKDLDHLKLVFIDSELDSTLENHIHFRDLAQADENEMKEVNIKINPDDVVALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYYHKEDVILCVLPMFHIYSLNSVLLCGLRAKAAILLMPKFDINAFLSHVNKYKVTIAPVVPPIVLAIAKSPDLHKYDLSSIRVLKSGGAPLGKELEDSVRAKFPKAKLGQGYGMTEAGPVLTMCLSFAKEPIDVKAGACGTVVRNAEMKIVDPENDSSLPRNQPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDIGYIDDDDELFIVDRLKELIKYKGFQVAPAELEAIILSHPQIYDVAVVPMKDEAAGEVPVAFVVKSNSQINTTEDEIKQFVSKQVVFYKRINRVFFIDAIPKSPSGKILRKDLRAKLAAGVPN
>rna-XM_004507784.3
MSPSPPQQEEEFIFRSKLPDIQIPTHLPLHSYCFQNLSQFHNRPCLINGDTGETLTYSDVHLTVRKIAAGLNSTLGINQGDVIMLVLRNSHQFALTFLGASYRGAVVTTANPFYTSSELAKQATATKTKLIVTQSAYINKINEFAKINKIKIVCTDSSPASSSDEESVVHFSVLTNADEKDAPEVKISPNDVVALPFSSGTSGLPKGVMLTHENLVTTIAQLVDGENPHQYTKYEDVLLCVLPMFHIYALNSILLSGIRSGAAVLIVEKFEITTLLELIDKYKVTVVSFVPPIVLALVKSGESNRYDLSCIRAMITGAAPMGVELEQAVKDRLPQAILGQGYGMTEAGPLSISMSFAKEAMGTKPGACGTVVRNAEMKIVDTETGHSLPRNKPGEICIRGTKVMKGYLNDPEATKRTIDKDGWLHTGDIGLIDDDDELFIVDRLKELIKYKGYQVAPAELEALLISHPNISDAAVVPLKDEAAGEVPVAFVVRSNGSKITEDEIKQYISKQVVFYKRINIVFFVDTIPKAASGKILRKELTARLNEGLVVAT
>rna-XM_004511366.3
MLSVAPSVDAKQTTEVSASVTKLNTQQQEPTDFNHNHNHDRDDNTNSIISSQNNLIFKSKLPDIPLSNHLPLHTYCFEKLPEITDRPCLIVASTGKIYTYGEAHLLSRKIAAGMSKLGIQKGDVIMILLQNSAEFVLSFIAASMIGAVATTANPFYTAAELFKQLTVCKTKLIITQAMYVDKLKQNEENGEFDFKIITVDEPPVNCLHFSVISEGNEEELLEVEIDPEDAVALPFSSGTTGLPKGVILTHKSLTTSVAQQVDGENPNLYLTTEDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMHKFEIGTLLDVIQKHRVTVAMVVPPLVLALAKNPSVAEFDLSSIRLVLSGAAPLGKELEEALHNRIPQAVLGQGYGMTEAGPVLSMSLSFAKQPLPTKSGSCGTVVRNAELKVLDPETGHSLGYNQPGEICIRGQQIMKGYLNDENATKTTIDEEGWLHTGDVGYIDDDDEIFIVDRVKELIKFKGFQVPPAELEGLLVSHPSIADAAVVPQKDVAAGEVPVAFVVRSNGFDLTEEAVKEFISKQVVFYKRLHKVYFIHAIPKSPAGKILRKDLRAKLENATQTI
>rna-XM_004516041.2
MGTYIENFVEEKEHIFRSQYSPVPVPDNVTLPEFVLQNVELYGDKVAFVDAESGKCVTYSEVERDIHRFSKALRSLGLRKGNVVIVVLPNIVEYAIVALGIMDSGGVFSGANPTLHASEIKKQAESADAKLIVTNSVTHEKVKNLGLPIIVLGDELIEDAMNWNKLLEAADRAGDDSMKEQIHQNDLCAMPFSSGTTGLSKGVMLTHRNLVANLCSTLFGVAQEMIGQVTTLGLIPFFHIYGITGICCATIRNKGKVVVMGRFDLKTFLNALITHEVTFAPIVPPIILGLVKNPIVDEFDLTKLKLQAIMTAAAPLAPEILTSFEHKFPGVLVQEAYGLTEHSCITLTHAQKGYGNTHKNSVGFILPNLEVKFIDPDTGRSLPRNTPGELCVRSQCVMQGYYKQVDETAQTIDNNGWLHTGDVGFIDDEENVFIVDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPNEEAGEIPAASVVLSIGAKESEQDIMNYVASNAAHYKKVRVVHFVEAIPKSPSGKIMRRLIKEKMVEKMKENSLTKSNTSSN
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University