Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Chiococca alba
Species name
Chiococca alba is a species of eudicot in the family Rubiaceae (madder family).
Species info
Gene sequence info
Chiococca_alba.COMT.fa
Download
>g1335.t1
MGNSEKNQVKSSSSSDEQSYPFSYVMQLVSSASLSMVLYTAVKLKLFEIIANAGAGAKLSASEIASRLPAATQNPYAASMLDRMLCLLSSYSLLTCDVVEEVAAGAGGENAVKFGRVYGLSMFAKYLVPDEDGDSMAPLVELLHDKVILDGWYELGNAVLEGGIPFNRAHGTHAFDYPSRDPRYNEVFNKGMVGPTALTMKTLLQQYRGFEHLQTLVDVGGGLGITLHKIISKHPSIKGINFDLPHVIENAPLYPGVEHIGGDMFESVPGGDAIFMKMILHDWSDDHCLKLLKNCFKALPDHGKVIVVDLILPAKPDTTTFAKGIFQADVLMMTQNPGGKERSEADVRTLAIGAGFKDIKLECLVGSAGVLELYK
>g2173.t1
MQLVASASLPMVLYAAVQLQLFEIIAKAGSRVKLSATEIASQLQTKNLDAGSMIDRILRLLSCHSVLTCDVVEIVNRGSTNENDLIHERVYGLSSIGQYFVPDEEGNSLAPAVKLLNDKVFIDSWFELGNAILEGGIPFNRVHGIHAFEYSSRYPKFNELFNKGMVGVTTLIMKELLQQYKGFQHLRTLVDIGGGHGIALHKIISKYPYISGINFDLPHVIENAPSYPGIFKISLPFKFFDTGVEHIGGDMFESVPRGDAMLMKMILHDWSDDHCLKLLKNCIKALPNNGKIIIVDMLLPVTPNSSVSSKTICQSDVLMMTQHIGGKERTENEIQNLAIGAGFRGIELQCIVGNVGVLELYK
>g10358.t1
MGSKQGEELIVEDKQQELLKLLELAYAPTLHAAFATAIELNLFEIIANSGPNALLSSAEIASRLPTKNPEAQAILERILLLLSSYSILKCSLISSENGHTTKLFGLTPICKHLVPDSDGISLAPAILISREKAHTECSYFLKDAILEGGSPFHKANGMHLFEFIGNSSGSIQEHFNRFMVSHTSIFMTLMLETYNGFENLNEVVDVGGGLGAALKIIVSKYPRIRGINFDLPFVIKNAPAYPGVEHVEGDMFQCVPRGEAILLKHILHNWTDDQCLKVLKNCWDALPKSGKVIAIDATLPEFPNTDSQSQLAYVADLEMLLVTTGKERTLKEFETLATKAGFTACKLAAITGPFGVIEFYKN
>g20815.t1
MGSRKQENISNTEEEACSLAMQLASASVLPMVLKSAIELDLLELIAKAGEDAYVSPSQLAAQLPTQNPEAPVMLDRILRLLASYSVLNCKLNHLSDGGVERLYGLAPVCKFLTKNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDTRFNKVFNQGMSNHSTIIMKKILDVYKGFEGLKTIVDVGGGTGATLNMIISKYPTIKGINFELPHVVEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCRKVLKNCYEALPENGKVILAECILPEAPDSSLATQNVVHVDVVMLAHNPGGKERTEKEFEALAKGAGFREFRKICTAFNLSWIMELRK
>g21628.t1
MSLLNPYERDLLMSLYWRSGYVVHSVFWCAVELNLFEIIAKAGPDAEISAAEIVSHLPTQNEEAAAILDRMLQLLSSYSILKATLVDGHTRRLYGLTPISKCLLPDEDGISMTSTPAFFAKDTAIKQSWDCLKDVVLEGGIPFEKANGMHLFEYLAKNQKQNIEFNEAMKTDSILSVREILETYRGFEDLKEVVDVGGGIGITLNVIISKYPWIQGINYDLPHVIKSAPAYPAGVEHVQGDMFEFIPKGEVILLKHILHDWEDENCLKILKNCWAALPDSGKVIIIDAILPEYPENDLSSRIGFVSDLCMLMVTPGGRERTQKQFESLAKGAGFASSKLVCRTTQFGVLEFYKN
>g27115.t1
MVKPWNFMAEWFQNHDNFPFDTAHKKNFWEFSAGDPRFQKIFNEGMASDDSEFITKVLHSDQCRFVFEGLTSLVNVGGLHRHSCYSHCENFLRYEVHGV
>g27375.t1
MLLLRHAASNCGGAADSLKHCRMTGCPRHYCQSWSGCTTIIIRDPSHLPTKNPHAHALLDQMLCLLANYLVLSCSIVHDGACDQYHRCFGLPPLAKYFVKQEYVAPLRPLLACLQDKVMMDPL
>g27412.t1_g27413.t1
MESSSWAESQQAKNGKEDEECFSYAMQLVTAAALPMVLNAVVRLDVLDIIAKAGLGAQLSSSEIASHLPTKNPHAPALLDRMLCLLANYSVLSCSVVHGGAGDQYQRRFGLAPVAKYFIKQQYGAPLRPLLACLQDKVLMDPWYQLEGAVLEGGNAFERTYGTEAFTYIGNDPRFCETFYNAMTCHTTAVLEEVLKCYKGFRDVKTLADVGGAHGHALHMITSKYPNIKGINFDLPNVIKLAPSYPGVEHKEGDMFESVPEADAIFMKWILHDWDDEHCLKLLRNCYKALPNNGKVVAVEVVVPTNPESSGAAIKSNIHYDLIMMMVCSPGAKERSELEFLVLATKAGFKGIRVECHVFNLCVMEFYK
>g32661.t1
MLDLYGRSLPYSQLPAHNPAISCHARLNSPTPGCPFRSPLHAQESSRWLRFERLYALAPVCNLLIMNADGVSIAALSLMHQDKVLMESWYHLKDAVLYGGIPFNRAYGMTAFECYGTDPRFNKVFNQGMSNHSTIIMKKILDVYLGYDGLETIVDVGGGRGATLNMIIRKYPTI
>g32662.t1
MLGDAIFMKWICHDWSDEHCLKLLKNCYEALAEHGKVILGEYVLPESPDAWPATKNVVHVDVVMLAHNPGGKERTGKEFEALAEGAGFKEFRNVCFAFSVWIMELCKMYVIGNPNLAIWDLGGPSILFYDCATGFY
MGNSEKNQVKSSSSSDEQSYPFSYVMQLVSSASLSMVLYTAVKLKLFEIIANAGAGAKLSASEIASRLPAATQNPYAASMLDRMLCLLSSYSLLTCDVVEEVAAGAGGENAVKFGRVYGLSMFAKYLVPDEDGDSMAPLVELLHDKVILDGWYELGNAVLEGGIPFNRAHGTHAFDYPSRDPRYNEVFNKGMVGPTALTMKTLLQQYRGFEHLQTLVDVGGGLGITLHKIISKHPSIKGINFDLPHVIENAPLYPGVEHIGGDMFESVPGGDAIFMKMILHDWSDDHCLKLLKNCFKALPDHGKVIVVDLILPAKPDTTTFAKGIFQADVLMMTQNPGGKERSEADVRTLAIGAGFKDIKLECLVGSAGVLELYK
>g2173.t1
MQLVASASLPMVLYAAVQLQLFEIIAKAGSRVKLSATEIASQLQTKNLDAGSMIDRILRLLSCHSVLTCDVVEIVNRGSTNENDLIHERVYGLSSIGQYFVPDEEGNSLAPAVKLLNDKVFIDSWFELGNAILEGGIPFNRVHGIHAFEYSSRYPKFNELFNKGMVGVTTLIMKELLQQYKGFQHLRTLVDIGGGHGIALHKIISKYPYISGINFDLPHVIENAPSYPGIFKISLPFKFFDTGVEHIGGDMFESVPRGDAMLMKMILHDWSDDHCLKLLKNCIKALPNNGKIIIVDMLLPVTPNSSVSSKTICQSDVLMMTQHIGGKERTENEIQNLAIGAGFRGIELQCIVGNVGVLELYK
>g10358.t1
MGSKQGEELIVEDKQQELLKLLELAYAPTLHAAFATAIELNLFEIIANSGPNALLSSAEIASRLPTKNPEAQAILERILLLLSSYSILKCSLISSENGHTTKLFGLTPICKHLVPDSDGISLAPAILISREKAHTECSYFLKDAILEGGSPFHKANGMHLFEFIGNSSGSIQEHFNRFMVSHTSIFMTLMLETYNGFENLNEVVDVGGGLGAALKIIVSKYPRIRGINFDLPFVIKNAPAYPGVEHVEGDMFQCVPRGEAILLKHILHNWTDDQCLKVLKNCWDALPKSGKVIAIDATLPEFPNTDSQSQLAYVADLEMLLVTTGKERTLKEFETLATKAGFTACKLAAITGPFGVIEFYKN
>g20815.t1
MGSRKQENISNTEEEACSLAMQLASASVLPMVLKSAIELDLLELIAKAGEDAYVSPSQLAAQLPTQNPEAPVMLDRILRLLASYSVLNCKLNHLSDGGVERLYGLAPVCKFLTKNADGVSMAPLLLMNQDKVLMESWYHLKDAVLDGGIPFNKAYGMTAFEYHGTDTRFNKVFNQGMSNHSTIIMKKILDVYKGFEGLKTIVDVGGGTGATLNMIISKYPTIKGINFELPHVVEDAPSYPGVEHVGGDMFVSVPKGDAIFMKWICHDWSDEHCRKVLKNCYEALPENGKVILAECILPEAPDSSLATQNVVHVDVVMLAHNPGGKERTEKEFEALAKGAGFREFRKICTAFNLSWIMELRK
>g21628.t1
MSLLNPYERDLLMSLYWRSGYVVHSVFWCAVELNLFEIIAKAGPDAEISAAEIVSHLPTQNEEAAAILDRMLQLLSSYSILKATLVDGHTRRLYGLTPISKCLLPDEDGISMTSTPAFFAKDTAIKQSWDCLKDVVLEGGIPFEKANGMHLFEYLAKNQKQNIEFNEAMKTDSILSVREILETYRGFEDLKEVVDVGGGIGITLNVIISKYPWIQGINYDLPHVIKSAPAYPAGVEHVQGDMFEFIPKGEVILLKHILHDWEDENCLKILKNCWAALPDSGKVIIIDAILPEYPENDLSSRIGFVSDLCMLMVTPGGRERTQKQFESLAKGAGFASSKLVCRTTQFGVLEFYKN
>g27115.t1
MVKPWNFMAEWFQNHDNFPFDTAHKKNFWEFSAGDPRFQKIFNEGMASDDSEFITKVLHSDQCRFVFEGLTSLVNVGGLHRHSCYSHCENFLRYEVHGV
>g27375.t1
MLLLRHAASNCGGAADSLKHCRMTGCPRHYCQSWSGCTTIIIRDPSHLPTKNPHAHALLDQMLCLLANYLVLSCSIVHDGACDQYHRCFGLPPLAKYFVKQEYVAPLRPLLACLQDKVMMDPL
>g27412.t1_g27413.t1
MESSSWAESQQAKNGKEDEECFSYAMQLVTAAALPMVLNAVVRLDVLDIIAKAGLGAQLSSSEIASHLPTKNPHAPALLDRMLCLLANYSVLSCSVVHGGAGDQYQRRFGLAPVAKYFIKQQYGAPLRPLLACLQDKVLMDPWYQLEGAVLEGGNAFERTYGTEAFTYIGNDPRFCETFYNAMTCHTTAVLEEVLKCYKGFRDVKTLADVGGAHGHALHMITSKYPNIKGINFDLPNVIKLAPSYPGVEHKEGDMFESVPEADAIFMKWILHDWDDEHCLKLLRNCYKALPNNGKVVAVEVVVPTNPESSGAAIKSNIHYDLIMMMVCSPGAKERSELEFLVLATKAGFKGIRVECHVFNLCVMEFYK
>g32661.t1
MLDLYGRSLPYSQLPAHNPAISCHARLNSPTPGCPFRSPLHAQESSRWLRFERLYALAPVCNLLIMNADGVSIAALSLMHQDKVLMESWYHLKDAVLYGGIPFNRAYGMTAFECYGTDPRFNKVFNQGMSNHSTIIMKKILDVYLGYDGLETIVDVGGGRGATLNMIIRKYPTI
>g32662.t1
MLGDAIFMKWICHDWSDEHCLKLLKNCYEALAEHGKVILGEYVLPESPDAWPATKNVVHVDVVMLAHNPGGKERTGKEFEALAEGAGFKEFRNVCFAFSVWIMELCKMYVIGNPNLAIWDLGGPSILFYDCATGFY
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University