Enzyme
Found in hops (Humulus lupulus). The enzyme can also methylate xanthogalenol.
OMT
Enzyme
Xanthohumol 4-O-methyltransferase
Enzyme name
EC:2.1.1.338
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:desmethylxanthohumol 6'-O-methyltransferase
Sysname
S-adenosyl-L-methionine + desmethylxanthohumol = S-adenosyl-L-homocysteine + xanthohumol [RN:R08004]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];xanthohumol [CPD:C16417]
Product
Species information
Chiococca alba
Species name
Chiococca alba is a species of eudicot in the family Rubiaceae (madder family).
Species info
Gene sequence info
Chiococca_alba.OMT.fa
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>g103.t1
MRKFNSLSKQWILHNWSDEDCVKILKNCRNAIPQKDKGGKVLIIELVVENHKEENKMDEAELSFDLEMMVIFGTKERSKDEWEKIFKDAGFDDYKIFPVLAPRCIIELYP
>g1695.t1
MDLARNGDNTSELLDAQAHIWNHIFSFINSMSLKCAIQIGIIDIIHKHGQPMTLSKLIHALPINPTKALFIYRLMRILIHSGFIVKAKITKSDEEEEEEEGYILTSASKLLLKNDPLSVAPFLLAMLDPIVTDPWQHLSQWLQNDDESTFKTCYGMGFWELASHEPRLNQLFNEGMASDTRLISSILIKNCENVFLGLNSLVDVGGGTGTLAKNIAEAFPEIKCMVLDLPHVVDGLGGESKNLTYVGGDMFKAIPRADALVLKWILHDWSDEECIQILKKCKEAIPSKENGGKLIIIDILLNDQEGKKGDVYDHKAIETQLFSDILMMVAAKGRERTEKEWATLFSEAGFNDYKISPILGLRSLN
>g1694.t1
MDLARNGDATNELLDAQAHIWNHIFSFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIHALPINPAKALFIYRLMRILIHSGFIVKAKITKNDDDDDDNEEEKEEEGYTLTSASKLLLKNDPLSVAPFLLAMLDPILTDPWQHFSQWLQNDDESTFKTCHGMRFWELAGHEPRLNQLFNEGMASDARLISSILIKNCENVFLGLNSLVDVGGGTGPLAKNIAEAFPEMKCMVLDLPHVVDGLGGESKNLTYVGGDMLKAIPRADAVVLKWILHDWSDEECIQILKKCKEAIPSKEKGGKLIIIDILLNEQEEKKGDVYEHEAIETQLFFDIMMMVADKGRERTEKEWATLFSEAGFNDYKISPILGLRSLIEVYYY
>g1690.t1
MDLARNGDADELLEAQAHIWNHMFSFTNAMSLKCAIQLGILDIIHKHGHPMTLSKLIHALPINNAKAPFVHRLMRILIHSGFIIKSKNYTDQINDDEKEEGYMLTSASKLLLKNDPSSLTPYLLAMLDPIFIDPWQHFSQWFQDDEGTPFNTCHGMGLWELAGCEPRLNQFFNEAMASDARLISIVLIKNCKNVFLGLNSLVDVGGGTGNLAKIIADAFPEMKCSVLDLPHVVDGLEEGSKNLAYVGGDMFKAIPSADAVLLKWILHDWTDEECIQILKNCKKAIPSKEKGGKVIIIEMLVHEREKGANAEAIGTQVFFDMVMMVLTKGKERNEEQWAKLFSEAGFDDYKITPLGLRSLIEVYYY
>g1692.t1
MLLHEREKGANTEAIVTQVIFDMVMTVLSKGKERNEEQWAKLFSEAGFDVCKITPLGLRSLIEKDCGILNQFAYSLKCLTIVAVKDVS
>g1693.t1
MDLARNGDADELLDAQANIWNHVFSFINSMSLKCAIQLGILDIIHKHGHQMTLSELTQALPVNNAKAPFVYRLNSLVDVGGGRTGTMGKAIADTFPHMKCIVLDHPHVVDGLVDGSKNLAYVAGTMFEATPPADAVLLKMMVYVKGKERSEKEWAKLFSEAGFHDYKITPVLGLRSIIEVYYY
>g1691.t1
MDLVRNDDATNELLDAQAHIWNHVFSFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIHALPINPKKAFFVYRLMRILIHSGFIVKAKITENDDEEEEEGYTLTSASKLLLKNDPLSVAPFLLAMLDPILTDPWQHFSQWLQNDDESTFKTCHGMGFWELAGHEPRLNQLFNEGMASDARLISSILIKNSENNFLGLNSLVDVGGGTGTLAKNIAEAFPEMKCIVLDLHHVVDGLGVGSKNLTYVGGDMFKAIPPADAVVLKV
>g6082.t1
MEREKTEEVKAAEQAQVDIWKYIFGFTEMAVVKCAIELGIADVLESNQGQPMSLNQLSSALGCSPSSLYRIMRFLTSRSIFKQLPGGVTCYAQTPLSRLLARDGEQSMAALLLLESSPVMLDPWHKLSERVLANGPPSFEAAHGEDVWRYAEKNAAHSKLINDAMSCDARTAVSAMIDGCPQMLEGIRCLVDVGGGDGTALRTLRKACPWIRGINFDLPHVVSVAPRSDGIEHVAGNMFHSVPKADAAFIMWVLHDWGDEECISILRKCREAVPQDTGKVIIVEAVIDGGGEDKLKDVGLMLDMVMMAHTSTGKERTSEEWACILKEAGFSRHTVKTIRAVKSVIEAYP
>g10936.t1
METVENSSAELLRAQAHIWSQTFHFKNSASLKCAVQLGIADVIQKHGKPISLSDLASALPINPSKALHIDRLMRILVNAGFFAQENGKYVLNSAGRLLLKDEPMNARALVLMVLDPAMVKPWDFLSEWFQNDDPCPFDTAHGKDFWEYNAYEPKLRKLFNEGMASDSQLITKVLVNECKYVFEGLTSLVDVGGGTGTVARSIAKAFPNLKCTVCDLPHVVANQEGTQNLDFVAGDMLEKVPSANAILLKWILHDWSDEDCVKILKNCKKAVPGRDKGGKVIIIDMIMESQTEDPESVEAQISLDMQMLVLYGAKERTEKEWATLFWDAGFGSYKVFPVLGTRGLIEVYP
>g23358.t1
MDLARNGDADELLKAQAHIWNHMVKFVDSMSLKCAIQLGIPDTIHKHGQPMTLSQLIRALSINDAKAPFIYRLMQILIHSGFVVKAKITENNEEEEEGEGYILTSASKLLLKNDPLSMRPLLLCHFDPILTDPCQHFSQWFQNDDETPFKTCHGMAFWELADHEPQFNRFFNEGMASDARLTGFVLIKKCKNVFAGLNSLVDVGGGTGNLAKTIADAFPHMNCIVLDVPRVVDGLVDGDYKNLTYVGGDMFKAIPPADAVLMKWVLHDWNDEECIQILENCKKAIPSQKKGGKLIIIDMVVNDEQQKGGGDDRETIETKLLNDVQQMAHLKGRERSEKDLAKLFSKAGFDDYNISSALGLRSLIEAYYY
>g27516.t1
MTLSELISALPMINSSKSPYIYRIMRLLVNSGFFVVEKDGYVLTSSSRIVLKDAPMSLRSSFLFFAFDPVAINPLKFLTEWFKNDDSTAFVTAYDKNVGISVLEILDFKSS
>g30000.t1
MKAIFSGFNDANWDSLESLVDVGGGTGAVIAEIVKVYPHIKGINFDLPHVVATAPKYNGVSHVGGDMFEAVPSAQAVFMKVFVDILYCQFYLFIVSI
>g29999.t1
MDKNDEGLELLKGQAEIWKHMFSFVGSMALKCAVELRIADIIHSHGHPLTLSEIASNITNSSTQNLSYLARIMRLLVRDKIFTASEIPNPPENGGRDHPSTTLYDLTAASRWLLHNNEEYLACLP
>g30001.t1
MKQVLDRCSSSLFSSSMQWIMHDWGDDDCVKILENCRRAIPVKTGKIFIVDVVLKPDGNGLFDSIGLIFDLLMIAHSSGGKERTESEWKKILEKGGFPRYSITEIPGCFSIIEAYP
>g33937.t1
MDLARNNSDAADKLLEAQAHIWNHILNFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIQALPVNTAKAPLVYRLMRFLIHSGSIVKAKITENDEEESYILTSASKLLLKNDPLSMTPLLLAMLDPILTDPWQHFSQWFQNNDVSPIKTCHGMAMWELAGREPRLNESFNEGMASDARLVSSVLMKNCKNVFSGLNSLVDVGGGTGTLAKNIADAFPEMKCMVLDLPQVVHGLGERSKNFITYVGGDMFKAIPLADAVLLKWILHDWSDKECIQILKNSKEAIPSKEKGGKVIIIDIVLNEQRHRGGDDHEAVETQLSIDMKMMVHHALQPSRKSGKVKEKIEDEFVIRRSGGRANVYFATVNTKRPS
>g34673.t1
MDSARNGDADEILESQAHIWNHLFSFINSMSLKCAVQLGILDIIHKHGHPMSHSKLIHALPINHAKAPFVYRLMRILIHSGFIIKAKMTENGDEEEEGYMLTSASKLLLKNDPLSVTPFLLAMLDPILTDAWQHFSQWFQNDDEIPFKTCHGMALWDLAGCKPRLNQFFNEGMASDARLVSSILMKNCQNVFFGLNSLVDVGGGTGTLAKSIADAFPHMKCFVLDLSHVVDGLGKGSKNLAYIGGDMFEAIPSADAVLLKWILHDWNDEDCIQILQKCKEAIPSKEKGGKVIIIDMVLNEQQEKGRDDAEATETQLFFDMLMMILVKGKERNEKEWAKLFSEAGFDDYKITPVLGLRSLIEVYYY
MRKFNSLSKQWILHNWSDEDCVKILKNCRNAIPQKDKGGKVLIIELVVENHKEENKMDEAELSFDLEMMVIFGTKERSKDEWEKIFKDAGFDDYKIFPVLAPRCIIELYP
>g1695.t1
MDLARNGDNTSELLDAQAHIWNHIFSFINSMSLKCAIQIGIIDIIHKHGQPMTLSKLIHALPINPTKALFIYRLMRILIHSGFIVKAKITKSDEEEEEEEGYILTSASKLLLKNDPLSVAPFLLAMLDPIVTDPWQHLSQWLQNDDESTFKTCYGMGFWELASHEPRLNQLFNEGMASDTRLISSILIKNCENVFLGLNSLVDVGGGTGTLAKNIAEAFPEIKCMVLDLPHVVDGLGGESKNLTYVGGDMFKAIPRADALVLKWILHDWSDEECIQILKKCKEAIPSKENGGKLIIIDILLNDQEGKKGDVYDHKAIETQLFSDILMMVAAKGRERTEKEWATLFSEAGFNDYKISPILGLRSLN
>g1694.t1
MDLARNGDATNELLDAQAHIWNHIFSFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIHALPINPAKALFIYRLMRILIHSGFIVKAKITKNDDDDDDNEEEKEEEGYTLTSASKLLLKNDPLSVAPFLLAMLDPILTDPWQHFSQWLQNDDESTFKTCHGMRFWELAGHEPRLNQLFNEGMASDARLISSILIKNCENVFLGLNSLVDVGGGTGPLAKNIAEAFPEMKCMVLDLPHVVDGLGGESKNLTYVGGDMLKAIPRADAVVLKWILHDWSDEECIQILKKCKEAIPSKEKGGKLIIIDILLNEQEEKKGDVYEHEAIETQLFFDIMMMVADKGRERTEKEWATLFSEAGFNDYKISPILGLRSLIEVYYY
>g1690.t1
MDLARNGDADELLEAQAHIWNHMFSFTNAMSLKCAIQLGILDIIHKHGHPMTLSKLIHALPINNAKAPFVHRLMRILIHSGFIIKSKNYTDQINDDEKEEGYMLTSASKLLLKNDPSSLTPYLLAMLDPIFIDPWQHFSQWFQDDEGTPFNTCHGMGLWELAGCEPRLNQFFNEAMASDARLISIVLIKNCKNVFLGLNSLVDVGGGTGNLAKIIADAFPEMKCSVLDLPHVVDGLEEGSKNLAYVGGDMFKAIPSADAVLLKWILHDWTDEECIQILKNCKKAIPSKEKGGKVIIIEMLVHEREKGANAEAIGTQVFFDMVMMVLTKGKERNEEQWAKLFSEAGFDDYKITPLGLRSLIEVYYY
>g1692.t1
MLLHEREKGANTEAIVTQVIFDMVMTVLSKGKERNEEQWAKLFSEAGFDVCKITPLGLRSLIEKDCGILNQFAYSLKCLTIVAVKDVS
>g1693.t1
MDLARNGDADELLDAQANIWNHVFSFINSMSLKCAIQLGILDIIHKHGHQMTLSELTQALPVNNAKAPFVYRLNSLVDVGGGRTGTMGKAIADTFPHMKCIVLDHPHVVDGLVDGSKNLAYVAGTMFEATPPADAVLLKMMVYVKGKERSEKEWAKLFSEAGFHDYKITPVLGLRSIIEVYYY
>g1691.t1
MDLVRNDDATNELLDAQAHIWNHVFSFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIHALPINPKKAFFVYRLMRILIHSGFIVKAKITENDDEEEEEGYTLTSASKLLLKNDPLSVAPFLLAMLDPILTDPWQHFSQWLQNDDESTFKTCHGMGFWELAGHEPRLNQLFNEGMASDARLISSILIKNSENNFLGLNSLVDVGGGTGTLAKNIAEAFPEMKCIVLDLHHVVDGLGVGSKNLTYVGGDMFKAIPPADAVVLKV
>g6082.t1
MEREKTEEVKAAEQAQVDIWKYIFGFTEMAVVKCAIELGIADVLESNQGQPMSLNQLSSALGCSPSSLYRIMRFLTSRSIFKQLPGGVTCYAQTPLSRLLARDGEQSMAALLLLESSPVMLDPWHKLSERVLANGPPSFEAAHGEDVWRYAEKNAAHSKLINDAMSCDARTAVSAMIDGCPQMLEGIRCLVDVGGGDGTALRTLRKACPWIRGINFDLPHVVSVAPRSDGIEHVAGNMFHSVPKADAAFIMWVLHDWGDEECISILRKCREAVPQDTGKVIIVEAVIDGGGEDKLKDVGLMLDMVMMAHTSTGKERTSEEWACILKEAGFSRHTVKTIRAVKSVIEAYP
>g10936.t1
METVENSSAELLRAQAHIWSQTFHFKNSASLKCAVQLGIADVIQKHGKPISLSDLASALPINPSKALHIDRLMRILVNAGFFAQENGKYVLNSAGRLLLKDEPMNARALVLMVLDPAMVKPWDFLSEWFQNDDPCPFDTAHGKDFWEYNAYEPKLRKLFNEGMASDSQLITKVLVNECKYVFEGLTSLVDVGGGTGTVARSIAKAFPNLKCTVCDLPHVVANQEGTQNLDFVAGDMLEKVPSANAILLKWILHDWSDEDCVKILKNCKKAVPGRDKGGKVIIIDMIMESQTEDPESVEAQISLDMQMLVLYGAKERTEKEWATLFWDAGFGSYKVFPVLGTRGLIEVYP
>g23358.t1
MDLARNGDADELLKAQAHIWNHMVKFVDSMSLKCAIQLGIPDTIHKHGQPMTLSQLIRALSINDAKAPFIYRLMQILIHSGFVVKAKITENNEEEEEGEGYILTSASKLLLKNDPLSMRPLLLCHFDPILTDPCQHFSQWFQNDDETPFKTCHGMAFWELADHEPQFNRFFNEGMASDARLTGFVLIKKCKNVFAGLNSLVDVGGGTGNLAKTIADAFPHMNCIVLDVPRVVDGLVDGDYKNLTYVGGDMFKAIPPADAVLMKWVLHDWNDEECIQILENCKKAIPSQKKGGKLIIIDMVVNDEQQKGGGDDRETIETKLLNDVQQMAHLKGRERSEKDLAKLFSKAGFDDYNISSALGLRSLIEAYYY
>g27516.t1
MTLSELISALPMINSSKSPYIYRIMRLLVNSGFFVVEKDGYVLTSSSRIVLKDAPMSLRSSFLFFAFDPVAINPLKFLTEWFKNDDSTAFVTAYDKNVGISVLEILDFKSS
>g30000.t1
MKAIFSGFNDANWDSLESLVDVGGGTGAVIAEIVKVYPHIKGINFDLPHVVATAPKYNGVSHVGGDMFEAVPSAQAVFMKVFVDILYCQFYLFIVSI
>g29999.t1
MDKNDEGLELLKGQAEIWKHMFSFVGSMALKCAVELRIADIIHSHGHPLTLSEIASNITNSSTQNLSYLARIMRLLVRDKIFTASEIPNPPENGGRDHPSTTLYDLTAASRWLLHNNEEYLACLP
>g30001.t1
MKQVLDRCSSSLFSSSMQWIMHDWGDDDCVKILENCRRAIPVKTGKIFIVDVVLKPDGNGLFDSIGLIFDLLMIAHSSGGKERTESEWKKILEKGGFPRYSITEIPGCFSIIEAYP
>g33937.t1
MDLARNNSDAADKLLEAQAHIWNHILNFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIQALPVNTAKAPLVYRLMRFLIHSGSIVKAKITENDEEESYILTSASKLLLKNDPLSMTPLLLAMLDPILTDPWQHFSQWFQNNDVSPIKTCHGMAMWELAGREPRLNESFNEGMASDARLVSSVLMKNCKNVFSGLNSLVDVGGGTGTLAKNIADAFPEMKCMVLDLPQVVHGLGERSKNFITYVGGDMFKAIPLADAVLLKWILHDWSDKECIQILKNSKEAIPSKEKGGKVIIIDIVLNEQRHRGGDDHEAVETQLSIDMKMMVHHALQPSRKSGKVKEKIEDEFVIRRSGGRANVYFATVNTKRPS
>g34673.t1
MDSARNGDADEILESQAHIWNHLFSFINSMSLKCAVQLGILDIIHKHGHPMSHSKLIHALPINHAKAPFVYRLMRILIHSGFIIKAKMTENGDEEEEGYMLTSASKLLLKNDPLSVTPFLLAMLDPILTDAWQHFSQWFQNDDEIPFKTCHGMALWDLAGCKPRLNQFFNEGMASDARLVSSILMKNCQNVFFGLNSLVDVGGGTGTLAKSIADAFPHMKCFVLDLSHVVDGLGKGSKNLAYIGGDMFEAIPSADAVLLKWILHDWNDEDCIQILQKCKEAIPSKEKGGKVIIIDMVLNEQQEKGRDDAEATETQLFFDMLMMILVKGKERNEKEWAKLFSEAGFDDYKITPVLGLRSLIEVYYY
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University