Enzyme
The enzyme catalyses the biosynthesis of pterostilbene from resveratrol.
ROMT
Enzyme
Trans-resveratrol di-O-methyltransferase
Enzyme name
EC:2.1.1.240
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:trans-resveratrol 3,5-O-dimethyltransferase
Sysname
2 S-adenosyl-L-methionine + trans-resveratrol = 2 S-adenosyl-L-homocysteine + pterostilbene (overall reaction) [RN:R09872];(1a) S-adenosyl-L-methionine + trans-resveratrol = S-adenosyl-L-homocysteine + 3-methoxy-4',5-dihydroxy-trans-stilbene [RN:R09870];(1b) S-adenosyl-L-methionine + 3-methoxy-4',5-dihydroxy-trans-stilbene = S-adenosyl-L-homocysteine + pterostilbene [RN:R09871]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];pterostilbene [CPD:C10287];3-methoxy-4',5-dihydroxy-trans-stilbene [CPD:C20154]
Product
Species information
Chiococca alba
Species name
Chiococca alba is a species of eudicot in the family Rubiaceae (madder family).
Species info
Gene sequence info
Chiococca_alba.ROMT.fa
Download
>g103.t1
MRKFNSLSKQWILHNWSDEDCVKILKNCRNAIPQKDKGGKVLIIELVVENHKEENKMDEAELSFDLEMMVIFGTKERSKDEWEKIFKDAGFDDYKIFPVLAPRCIIELYP
>g1695.t1
MDLARNGDNTSELLDAQAHIWNHIFSFINSMSLKCAIQIGIIDIIHKHGQPMTLSKLIHALPINPTKALFIYRLMRILIHSGFIVKAKITKSDEEEEEEEGYILTSASKLLLKNDPLSVAPFLLAMLDPIVTDPWQHLSQWLQNDDESTFKTCYGMGFWELASHEPRLNQLFNEGMASDTRLISSILIKNCENVFLGLNSLVDVGGGTGTLAKNIAEAFPEIKCMVLDLPHVVDGLGGESKNLTYVGGDMFKAIPRADALVLKWILHDWSDEECIQILKKCKEAIPSKENGGKLIIIDILLNDQEGKKGDVYDHKAIETQLFSDILMMVAAKGRERTEKEWATLFSEAGFNDYKISPILGLRSLN
>g1694.t1
MDLARNGDATNELLDAQAHIWNHIFSFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIHALPINPAKALFIYRLMRILIHSGFIVKAKITKNDDDDDDNEEEKEEEGYTLTSASKLLLKNDPLSVAPFLLAMLDPILTDPWQHFSQWLQNDDESTFKTCHGMRFWELAGHEPRLNQLFNEGMASDARLISSILIKNCENVFLGLNSLVDVGGGTGPLAKNIAEAFPEMKCMVLDLPHVVDGLGGESKNLTYVGGDMLKAIPRADAVVLKWILHDWSDEECIQILKKCKEAIPSKEKGGKLIIIDILLNEQEEKKGDVYEHEAIETQLFFDIMMMVADKGRERTEKEWATLFSEAGFNDYKISPILGLRSLIEVYYY
>g1690.t1
MDLARNGDADELLEAQAHIWNHMFSFTNAMSLKCAIQLGILDIIHKHGHPMTLSKLIHALPINNAKAPFVHRLMRILIHSGFIIKSKNYTDQINDDEKEEGYMLTSASKLLLKNDPSSLTPYLLAMLDPIFIDPWQHFSQWFQDDEGTPFNTCHGMGLWELAGCEPRLNQFFNEAMASDARLISIVLIKNCKNVFLGLNSLVDVGGGTGNLAKIIADAFPEMKCSVLDLPHVVDGLEEGSKNLAYVGGDMFKAIPSADAVLLKWILHDWTDEECIQILKNCKKAIPSKEKGGKVIIIEMLVHEREKGANAEAIGTQVFFDMVMMVLTKGKERNEEQWAKLFSEAGFDDYKITPLGLRSLIEVYYY
>g1692.t1
MLLHEREKGANTEAIVTQVIFDMVMTVLSKGKERNEEQWAKLFSEAGFDVCKITPLGLRSLIEKDCGILNQFAYSLKCLTIVAVKDVS
>g1693.t1
MDLARNGDADELLDAQANIWNHVFSFINSMSLKCAIQLGILDIIHKHGHQMTLSELTQALPVNNAKAPFVYRLNSLVDVGGGRTGTMGKAIADTFPHMKCIVLDHPHVVDGLVDGSKNLAYVAGTMFEATPPADAVLLKMMVYVKGKERSEKEWAKLFSEAGFHDYKITPVLGLRSIIEVYYY
>g1691.t1
MDLVRNDDATNELLDAQAHIWNHVFSFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIHALPINPKKAFFVYRLMRILIHSGFIVKAKITENDDEEEEEGYTLTSASKLLLKNDPLSVAPFLLAMLDPILTDPWQHFSQWLQNDDESTFKTCHGMGFWELAGHEPRLNQLFNEGMASDARLISSILIKNSENNFLGLNSLVDVGGGTGTLAKNIAEAFPEMKCIVLDLHHVVDGLGVGSKNLTYVGGDMFKAIPPADAVVLKV
>g10936.t1
METVENSSAELLRAQAHIWSQTFHFKNSASLKCAVQLGIADVIQKHGKPISLSDLASALPINPSKALHIDRLMRILVNAGFFAQENGKYVLNSAGRLLLKDEPMNARALVLMVLDPAMVKPWDFLSEWFQNDDPCPFDTAHGKDFWEYNAYEPKLRKLFNEGMASDSQLITKVLVNECKYVFEGLTSLVDVGGGTGTVARSIAKAFPNLKCTVCDLPHVVANQEGTQNLDFVAGDMLEKVPSANAILLKWILHDWSDEDCVKILKNCKKAVPGRDKGGKVIIIDMIMESQTEDPESVEAQISLDMQMLVLYGAKERTEKEWATLFWDAGFGSYKVFPVLGTRGLIEVYP
>g23358.t1
MDLARNGDADELLKAQAHIWNHMVKFVDSMSLKCAIQLGIPDTIHKHGQPMTLSQLIRALSINDAKAPFIYRLMQILIHSGFVVKAKITENNEEEEEGEGYILTSASKLLLKNDPLSMRPLLLCHFDPILTDPCQHFSQWFQNDDETPFKTCHGMAFWELADHEPQFNRFFNEGMASDARLTGFVLIKKCKNVFAGLNSLVDVGGGTGNLAKTIADAFPHMNCIVLDVPRVVDGLVDGDYKNLTYVGGDMFKAIPPADAVLMKWVLHDWNDEECIQILENCKKAIPSQKKGGKLIIIDMVVNDEQQKGGGDDRETIETKLLNDVQQMAHLKGRERSEKDLAKLFSKAGFDDYNISSALGLRSLIEAYYY
>g27115.t1
MVKPWNFMAEWFQNHDNFPFDTAHKKNFWEFSAGDPRFQKIFNEGMASDDSEFITKVLHSDQCRFVFEGLTSLVNVGGLHRHSCYSHCENFLRYEVHGV
>g27516.t1
MTLSELISALPMINSSKSPYIYRIMRLLVNSGFFVVEKDGYVLTSSSRIVLKDAPMSLRSSFLFFAFDPVAINPLKFLTEWFKNDDSTAFVTAYDKNVGISVLEILDFKSS
>g33937.t1
MDLARNNSDAADKLLEAQAHIWNHILNFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIQALPVNTAKAPLVYRLMRFLIHSGSIVKAKITENDEEESYILTSASKLLLKNDPLSMTPLLLAMLDPILTDPWQHFSQWFQNNDVSPIKTCHGMAMWELAGREPRLNESFNEGMASDARLVSSVLMKNCKNVFSGLNSLVDVGGGTGTLAKNIADAFPEMKCMVLDLPQVVHGLGERSKNFITYVGGDMFKAIPLADAVLLKWILHDWSDKECIQILKNSKEAIPSKEKGGKVIIIDIVLNEQRHRGGDDHEAVETQLSIDMKMMVHHALQPSRKSGKVKEKIEDEFVIRRSGGRANVYFATVNTKRPS
>g34673.t1
MDSARNGDADEILESQAHIWNHLFSFINSMSLKCAVQLGILDIIHKHGHPMSHSKLIHALPINHAKAPFVYRLMRILIHSGFIIKAKMTENGDEEEEGYMLTSASKLLLKNDPLSVTPFLLAMLDPILTDAWQHFSQWFQNDDEIPFKTCHGMALWDLAGCKPRLNQFFNEGMASDARLVSSILMKNCQNVFFGLNSLVDVGGGTGTLAKSIADAFPHMKCFVLDLSHVVDGLGKGSKNLAYIGGDMFEAIPSADAVLLKWILHDWNDEDCIQILQKCKEAIPSKEKGGKVIIIDMVLNEQQEKGRDDAEATETQLFFDMLMMILVKGKERNEKEWAKLFSEAGFDDYKITPVLGLRSLIEVYYY
MRKFNSLSKQWILHNWSDEDCVKILKNCRNAIPQKDKGGKVLIIELVVENHKEENKMDEAELSFDLEMMVIFGTKERSKDEWEKIFKDAGFDDYKIFPVLAPRCIIELYP
>g1695.t1
MDLARNGDNTSELLDAQAHIWNHIFSFINSMSLKCAIQIGIIDIIHKHGQPMTLSKLIHALPINPTKALFIYRLMRILIHSGFIVKAKITKSDEEEEEEEGYILTSASKLLLKNDPLSVAPFLLAMLDPIVTDPWQHLSQWLQNDDESTFKTCYGMGFWELASHEPRLNQLFNEGMASDTRLISSILIKNCENVFLGLNSLVDVGGGTGTLAKNIAEAFPEIKCMVLDLPHVVDGLGGESKNLTYVGGDMFKAIPRADALVLKWILHDWSDEECIQILKKCKEAIPSKENGGKLIIIDILLNDQEGKKGDVYDHKAIETQLFSDILMMVAAKGRERTEKEWATLFSEAGFNDYKISPILGLRSLN
>g1694.t1
MDLARNGDATNELLDAQAHIWNHIFSFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIHALPINPAKALFIYRLMRILIHSGFIVKAKITKNDDDDDDNEEEKEEEGYTLTSASKLLLKNDPLSVAPFLLAMLDPILTDPWQHFSQWLQNDDESTFKTCHGMRFWELAGHEPRLNQLFNEGMASDARLISSILIKNCENVFLGLNSLVDVGGGTGPLAKNIAEAFPEMKCMVLDLPHVVDGLGGESKNLTYVGGDMLKAIPRADAVVLKWILHDWSDEECIQILKKCKEAIPSKEKGGKLIIIDILLNEQEEKKGDVYEHEAIETQLFFDIMMMVADKGRERTEKEWATLFSEAGFNDYKISPILGLRSLIEVYYY
>g1690.t1
MDLARNGDADELLEAQAHIWNHMFSFTNAMSLKCAIQLGILDIIHKHGHPMTLSKLIHALPINNAKAPFVHRLMRILIHSGFIIKSKNYTDQINDDEKEEGYMLTSASKLLLKNDPSSLTPYLLAMLDPIFIDPWQHFSQWFQDDEGTPFNTCHGMGLWELAGCEPRLNQFFNEAMASDARLISIVLIKNCKNVFLGLNSLVDVGGGTGNLAKIIADAFPEMKCSVLDLPHVVDGLEEGSKNLAYVGGDMFKAIPSADAVLLKWILHDWTDEECIQILKNCKKAIPSKEKGGKVIIIEMLVHEREKGANAEAIGTQVFFDMVMMVLTKGKERNEEQWAKLFSEAGFDDYKITPLGLRSLIEVYYY
>g1692.t1
MLLHEREKGANTEAIVTQVIFDMVMTVLSKGKERNEEQWAKLFSEAGFDVCKITPLGLRSLIEKDCGILNQFAYSLKCLTIVAVKDVS
>g1693.t1
MDLARNGDADELLDAQANIWNHVFSFINSMSLKCAIQLGILDIIHKHGHQMTLSELTQALPVNNAKAPFVYRLNSLVDVGGGRTGTMGKAIADTFPHMKCIVLDHPHVVDGLVDGSKNLAYVAGTMFEATPPADAVLLKMMVYVKGKERSEKEWAKLFSEAGFHDYKITPVLGLRSIIEVYYY
>g1691.t1
MDLVRNDDATNELLDAQAHIWNHVFSFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIHALPINPKKAFFVYRLMRILIHSGFIVKAKITENDDEEEEEGYTLTSASKLLLKNDPLSVAPFLLAMLDPILTDPWQHFSQWLQNDDESTFKTCHGMGFWELAGHEPRLNQLFNEGMASDARLISSILIKNSENNFLGLNSLVDVGGGTGTLAKNIAEAFPEMKCIVLDLHHVVDGLGVGSKNLTYVGGDMFKAIPPADAVVLKV
>g10936.t1
METVENSSAELLRAQAHIWSQTFHFKNSASLKCAVQLGIADVIQKHGKPISLSDLASALPINPSKALHIDRLMRILVNAGFFAQENGKYVLNSAGRLLLKDEPMNARALVLMVLDPAMVKPWDFLSEWFQNDDPCPFDTAHGKDFWEYNAYEPKLRKLFNEGMASDSQLITKVLVNECKYVFEGLTSLVDVGGGTGTVARSIAKAFPNLKCTVCDLPHVVANQEGTQNLDFVAGDMLEKVPSANAILLKWILHDWSDEDCVKILKNCKKAVPGRDKGGKVIIIDMIMESQTEDPESVEAQISLDMQMLVLYGAKERTEKEWATLFWDAGFGSYKVFPVLGTRGLIEVYP
>g23358.t1
MDLARNGDADELLKAQAHIWNHMVKFVDSMSLKCAIQLGIPDTIHKHGQPMTLSQLIRALSINDAKAPFIYRLMQILIHSGFVVKAKITENNEEEEEGEGYILTSASKLLLKNDPLSMRPLLLCHFDPILTDPCQHFSQWFQNDDETPFKTCHGMAFWELADHEPQFNRFFNEGMASDARLTGFVLIKKCKNVFAGLNSLVDVGGGTGNLAKTIADAFPHMNCIVLDVPRVVDGLVDGDYKNLTYVGGDMFKAIPPADAVLMKWVLHDWNDEECIQILENCKKAIPSQKKGGKLIIIDMVVNDEQQKGGGDDRETIETKLLNDVQQMAHLKGRERSEKDLAKLFSKAGFDDYNISSALGLRSLIEAYYY
>g27115.t1
MVKPWNFMAEWFQNHDNFPFDTAHKKNFWEFSAGDPRFQKIFNEGMASDDSEFITKVLHSDQCRFVFEGLTSLVNVGGLHRHSCYSHCENFLRYEVHGV
>g27516.t1
MTLSELISALPMINSSKSPYIYRIMRLLVNSGFFVVEKDGYVLTSSSRIVLKDAPMSLRSSFLFFAFDPVAINPLKFLTEWFKNDDSTAFVTAYDKNVGISVLEILDFKSS
>g33937.t1
MDLARNNSDAADKLLEAQAHIWNHILNFINSMSLKCAIQLGIPDIIHKHGQPMTLSKLIQALPVNTAKAPLVYRLMRFLIHSGSIVKAKITENDEEESYILTSASKLLLKNDPLSMTPLLLAMLDPILTDPWQHFSQWFQNNDVSPIKTCHGMAMWELAGREPRLNESFNEGMASDARLVSSVLMKNCKNVFSGLNSLVDVGGGTGTLAKNIADAFPEMKCMVLDLPQVVHGLGERSKNFITYVGGDMFKAIPLADAVLLKWILHDWSDKECIQILKNSKEAIPSKEKGGKVIIIDIVLNEQRHRGGDDHEAVETQLSIDMKMMVHHALQPSRKSGKVKEKIEDEFVIRRSGGRANVYFATVNTKRPS
>g34673.t1
MDSARNGDADEILESQAHIWNHLFSFINSMSLKCAVQLGILDIIHKHGHPMSHSKLIHALPINHAKAPFVYRLMRILIHSGFIIKAKMTENGDEEEEGYMLTSASKLLLKNDPLSVTPFLLAMLDPILTDAWQHFSQWFQNDDEIPFKTCHGMALWDLAGCKPRLNQFFNEGMASDARLVSSILMKNCQNVFFGLNSLVDVGGGTGTLAKSIADAFPHMKCFVLDLSHVVDGLGKGSKNLAYIGGDMFEAIPSADAVLLKWILHDWNDEDCIQILQKCKEAIPSKEKGGKVIIIDMVLNEQQEKGRDDAEATETQLFFDMLMMILVKGKERNEKEWAKLFSEAGFDDYKITPVLGLRSLIEVYYY
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University