Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Chiococca alba
Species name
Chiococca alba is a species of eudicot in the family Rubiaceae (madder family).
Species info
Gene sequence info
Chiococca_alba.CHS.fa
Download
>g2777.t1
MGEKSMINKRYTYLTEEILKKNPNICAYMAPSLDARQDMVVVEVPKLGKEAAQKAIEERGQPKSKITHLIFCATAGVGMPGADYQLTKLLGLCPSVKRLMIYQQGCFAGGMVLRLAKDLAENNKDARVLVVCSEIAAISFRGPSDTHLDILLSQALFGDGASAVIIGADPVPEIERPLFELVLAAQTIIPDSHGVLKGHFREVGLIYKLLKGVPELISKNLEKILEEAFKPLGISDWNSLFWIAHPGGPAILDQIEAKLGPKPEKLRATRHVLSEYGNMSSPCVLFILDEMRKASVRDGHNTTGEGLEWGVLFGFGAGFTVETVVLHSVST
>g2774.t1
MQSRNGANPSPSKITHLIFCSTAGVDMPGADYQLTKLLDLSPSVKRYMLYQQACFAGGTALRLAKDLAENNKDARVLVVCSEITALMFRGPSDTHLDILISQALFGDGASAVIIGADPIPEIERPLFELVSAAQTILPDSHGALEGHLREVGLTFHLLKDVPELISKNIEKSLEEAFEPLGICDWNSLFWVAHPGGPVILDQIEEKLGLNPEKLRATRHILSEYGNMSSACVLFILDEMRKSSVRNGYNTTGEGLEWGVLFSFGPGFTVLAHENCNPFLALKTQLQSVTKC
>g2778.t1
MLTVDEIRKAQRAEGPATIMAIGTATPPNCVEQSTYPDYYFRITNSEHMTELKEKFKRMCEKSTIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKDARVLVVCSEITAVTFRGPTDTHLDSLVGQALFGDGAAAIIVGADPNPETERPLFELVSAAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDQVEEKLALKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKASVRDGCNTTGEGLEWGVLFGFGPGLTVETVTLHSVST
>g2775.t1
MPGKIWWLLKYQNLAKKQPKRQSKNGVWTCLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMIYLQGCSAGAMVLRLAKDLAENNKDARVLVVCSEITAFMFRGLSDTQLDTLIGPALFGDGASAVIIGADPVPEFERPLFELVSAAQTIVPDSHGTLEGHLREVGLTFHLLKNVPELISKNIEKSLEESFKPLGISDWNSLFWITHPGGPVILNQVEEELRLKPEKLRATRHVLSEYGNMSSACVVFVLDEMRKASIRDGCSITGEGLEWGVLFGFGPGLTIETLVLHSVST
>g3264.t1
MVWQPIIVGADPIPGVERPLFELVSAAQTKLADSDGAIEGHLREVGLTFHLLKNVPLLISNNIEQALEEAFEPLEQLRATRYVLSEYGNMSSPSVLFILDEMRKASAKAGFRTTGERLEWGVLFDFGHGLTVEWFCIVFQ
>g3514.t1
MIIVEAPKLGKEASQIAIKGWGQAKSKITHPVFCTSSGVDMPGADYQLTKLLVVLFGDGAAAITIGADPDLEVERPLFELVSAAQTILPGSYGALAGHLGGPAILDKVEEKSDLKPEKLRATRHVLSEYGNLSSACVMFILDEMRNASIRDGYNTSGEGLDWGVLFGFGAGLTVETIVLHVLT
>g3498.t1
MAPSLDARQDMVIVEAPKLGKEASQIAIKGWGQAKSKITHLVFCTSSGVDMPGADYQLTKLLVLFGDGAAAIIIGADPYLEVERPLFELVSAAQTILPGSHGALAGHLGGPAILDQVEEKSDLKPEKLRATRHVLSEYGNLSSACVIFILDEMRNASIRDGYNTSGEGLDWGVLFGFGAGLIVEAIVLHVLT
>g6008.t1
MKEIQVHPEFIMQKDKMGSEEATHGLKTVTPGKATILALGKAFPHQLVMQEFLVDGYFKDTNCDDPDLKQKLARLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNSAVTQMAIEAAQSCIKNWGRPVSDITHLVYVSSSEVRLPGGDLYLAKGLGLRPETQRVMLNFSGCSGGVAGIRVAKDIAENNPGSRVLLATSETTIIGFRPPNAERPYDLVGVALFGDGAGAMIVGSGPEPSIESPLFELHTAMQHFLPDTEKIIDGRLTEEGISFKLGRELPQVIEDNIEGFCGKLMEVPGYFKKEYNKMFWAVHPGGPAILNRMEKKLDLLPEKLNASRRALADYGNASSNTIVYVLEYMLEENKKKIKVDQGEDEWGLILAFGPGITFEGILTKNLAA
>g9455.t1
MAPSLVARQDMVIVEAPPKLGKAASQIAIKGWGQAKSKITHLVFCTSSGVDMPGADYQLTKLLVVLFGDGAAAIIIGADPDLEVERPLFELVSAAQTILPGSHGALAGHLGGPAILDQVEEKSDLKPEKLRATRHVLSEYGNLSSACVMFILDEMRNASIRDGYNTSGEGLDWGVLFGFGAGLTVETIVLHVLT
>g19437.t1
MVTVEEVRRAQRAEGPASIMAIGTATPPNCVDQSNYPDYYFRVTNSEDKTELKEKFRRMCEKSMIKKRYMFLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTILRLAKDLAENNKGARVLVVASEITAVTFRGPSELHLDSLVGQALFGDGAAAMIIGADPVSGVERPLFELVSAAQTIVPDSHGAIDGHLREVGLTFHLLKDVPRLISNNIELALKEAFEPLGISNWNSLFWIAHPGGPAVLDQVEAKLGLEQEKLRATRHVLSEYGNMSSACVLFILDEMRKGSVKEGFCTTGEGLEWGVLFGFGPGLTVETVVLHSISI
>g21427.t1
MGSEDAIHGLKTATPGKATILALGKAFPHQLVMQEFLVDGYFKDTHCDDPDLKQKLSRLCKTTTVKTRYVVMSEEILNKYPELAVEGLPTVKQRLEICNSAVTQMATEAAQSCIKKWGRPVSDITHLVYVSSSEVRLPGGDLYLAKGLGLRPQTQRVMLNFSGCSGGVAGIRVAKDIAENNPGSRVLLATSETTIIGFRPPSAERPYDLVGVALFGDGAGAMIVGTNPELSIESPLFELHTAMQHFLPDTEKIIDGRLTEEGISFKLGKELPQVIEDNIEGFCSKLMEVAGYSKKDYNKMFWAVHPGGPAILNRMEKKLDLLPEKLNASRRALADYGNASSNTIVYVLEYMLEENKKERKEDQGDEEWGLVLAFGPGITFEGILTRTL
>g23625.t1
MASTSIEEIRQAQRAQGPATILAIGTATPSNCVYQVDYPDYYFRITQSEHKTDLKDKFKRMCEKSMIKKRYMHLTEDILKENPNICAYMAPSLDARQDIVVVEVPKLGKEAASKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAVIVGADPDTSLERPLFQLVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISRNIDKSLVEAFKPMGISDWNSIFWIAHPGGPAILDQVEAKLGLKQDKLRATRHVLSEYGNMSSACVLFILDEMRKKSIEAGKLTTGEGLEWGVLFGFGPGLTVETVVLHSVPATVN
>g27118.t1
MSKFNKNGTFRRIPTPGKATILSIGKAFPRQVVPQDCLVEGYVRDMKCDDLAIKEKLERLCKTTTVKTRYTVMSKEILEKYPELATEGSPTIKQRLEIANPAVVEMAKEASQACIKEWGRPVGDITHIVYVSSSEIRLPGGDLYLATELGLRSDVGRIMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPIIGTESPFMELNYAVQQFLPGTNNVIDGQLSEEGINFRLGRDLPQKIEDNIEEFCKKLMSKAGLDDFNDLFWAVHPGGPAILNRLESTLKLKTEKLECSRRTLMDFGNVSSNTIFYVMEYMKEELKREGSEEWGLALAFGPGITFEGILIRSL
>g28707.t1
MSRISKNGTSRRAPTPGKATVLSIGKAFPKQVVPQDCLVEGYVRDTKCMDQAIKEKLERLCKTTTVKTRYTVMSKEILDKYPELITEGSPTIKQRLEIANPAVVEMAKEASLACIKNWGRPVDDITHIVYVSSSEIRLPGGDLYLATELGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPVTGAESPFMELNYAVQQFLPGTNNVIDGRLSEEGINFRLGRDLPQKIEENIEAFCKKLMAKAGLDDFNDLFWAVHPGGPAILNRLESTLKLKAGKLECSRRTLMDFGNVSSNTIFYVMEYMREELQRDGSEEWGLALAFGPGITFEGILIRSL
MGEKSMINKRYTYLTEEILKKNPNICAYMAPSLDARQDMVVVEVPKLGKEAAQKAIEERGQPKSKITHLIFCATAGVGMPGADYQLTKLLGLCPSVKRLMIYQQGCFAGGMVLRLAKDLAENNKDARVLVVCSEIAAISFRGPSDTHLDILLSQALFGDGASAVIIGADPVPEIERPLFELVLAAQTIIPDSHGVLKGHFREVGLIYKLLKGVPELISKNLEKILEEAFKPLGISDWNSLFWIAHPGGPAILDQIEAKLGPKPEKLRATRHVLSEYGNMSSPCVLFILDEMRKASVRDGHNTTGEGLEWGVLFGFGAGFTVETVVLHSVST
>g2774.t1
MQSRNGANPSPSKITHLIFCSTAGVDMPGADYQLTKLLDLSPSVKRYMLYQQACFAGGTALRLAKDLAENNKDARVLVVCSEITALMFRGPSDTHLDILISQALFGDGASAVIIGADPIPEIERPLFELVSAAQTILPDSHGALEGHLREVGLTFHLLKDVPELISKNIEKSLEEAFEPLGICDWNSLFWVAHPGGPVILDQIEEKLGLNPEKLRATRHILSEYGNMSSACVLFILDEMRKSSVRNGYNTTGEGLEWGVLFSFGPGFTVLAHENCNPFLALKTQLQSVTKC
>g2778.t1
MLTVDEIRKAQRAEGPATIMAIGTATPPNCVEQSTYPDYYFRITNSEHMTELKEKFKRMCEKSTIKKRYMYLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKDARVLVVCSEITAVTFRGPTDTHLDSLVGQALFGDGAAAIIVGADPNPETERPLFELVSAAQTILPDSHGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLEEAFKPLGISDWNSLFWIAHPGGPAILDQVEEKLALKPEKLRSTRHVLSEYGNMSSACVLFILDEMRKASVRDGCNTTGEGLEWGVLFGFGPGLTVETVTLHSVST
>g2775.t1
MPGKIWWLLKYQNLAKKQPKRQSKNGVWTCLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMIYLQGCSAGAMVLRLAKDLAENNKDARVLVVCSEITAFMFRGLSDTQLDTLIGPALFGDGASAVIIGADPVPEFERPLFELVSAAQTIVPDSHGTLEGHLREVGLTFHLLKNVPELISKNIEKSLEESFKPLGISDWNSLFWITHPGGPVILNQVEEELRLKPEKLRATRHVLSEYGNMSSACVVFVLDEMRKASIRDGCSITGEGLEWGVLFGFGPGLTIETLVLHSVST
>g3264.t1
MVWQPIIVGADPIPGVERPLFELVSAAQTKLADSDGAIEGHLREVGLTFHLLKNVPLLISNNIEQALEEAFEPLEQLRATRYVLSEYGNMSSPSVLFILDEMRKASAKAGFRTTGERLEWGVLFDFGHGLTVEWFCIVFQ
>g3514.t1
MIIVEAPKLGKEASQIAIKGWGQAKSKITHPVFCTSSGVDMPGADYQLTKLLVVLFGDGAAAITIGADPDLEVERPLFELVSAAQTILPGSYGALAGHLGGPAILDKVEEKSDLKPEKLRATRHVLSEYGNLSSACVMFILDEMRNASIRDGYNTSGEGLDWGVLFGFGAGLTVETIVLHVLT
>g3498.t1
MAPSLDARQDMVIVEAPKLGKEASQIAIKGWGQAKSKITHLVFCTSSGVDMPGADYQLTKLLVLFGDGAAAIIIGADPYLEVERPLFELVSAAQTILPGSHGALAGHLGGPAILDQVEEKSDLKPEKLRATRHVLSEYGNLSSACVIFILDEMRNASIRDGYNTSGEGLDWGVLFGFGAGLIVEAIVLHVLT
>g6008.t1
MKEIQVHPEFIMQKDKMGSEEATHGLKTVTPGKATILALGKAFPHQLVMQEFLVDGYFKDTNCDDPDLKQKLARLCKTTTVKTRYVVMSEEILKKYPELAVEGLPTVKQRLDICNSAVTQMAIEAAQSCIKNWGRPVSDITHLVYVSSSEVRLPGGDLYLAKGLGLRPETQRVMLNFSGCSGGVAGIRVAKDIAENNPGSRVLLATSETTIIGFRPPNAERPYDLVGVALFGDGAGAMIVGSGPEPSIESPLFELHTAMQHFLPDTEKIIDGRLTEEGISFKLGRELPQVIEDNIEGFCGKLMEVPGYFKKEYNKMFWAVHPGGPAILNRMEKKLDLLPEKLNASRRALADYGNASSNTIVYVLEYMLEENKKKIKVDQGEDEWGLILAFGPGITFEGILTKNLAA
>g9455.t1
MAPSLVARQDMVIVEAPPKLGKAASQIAIKGWGQAKSKITHLVFCTSSGVDMPGADYQLTKLLVVLFGDGAAAIIIGADPDLEVERPLFELVSAAQTILPGSHGALAGHLGGPAILDQVEEKSDLKPEKLRATRHVLSEYGNLSSACVMFILDEMRNASIRDGYNTSGEGLDWGVLFGFGAGLTVETIVLHVLT
>g19437.t1
MVTVEEVRRAQRAEGPASIMAIGTATPPNCVDQSNYPDYYFRVTNSEDKTELKEKFRRMCEKSMIKKRYMFLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAQKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTILRLAKDLAENNKGARVLVVASEITAVTFRGPSELHLDSLVGQALFGDGAAAMIIGADPVSGVERPLFELVSAAQTIVPDSHGAIDGHLREVGLTFHLLKDVPRLISNNIELALKEAFEPLGISNWNSLFWIAHPGGPAVLDQVEAKLGLEQEKLRATRHVLSEYGNMSSACVLFILDEMRKGSVKEGFCTTGEGLEWGVLFGFGPGLTVETVVLHSISI
>g21427.t1
MGSEDAIHGLKTATPGKATILALGKAFPHQLVMQEFLVDGYFKDTHCDDPDLKQKLSRLCKTTTVKTRYVVMSEEILNKYPELAVEGLPTVKQRLEICNSAVTQMATEAAQSCIKKWGRPVSDITHLVYVSSSEVRLPGGDLYLAKGLGLRPQTQRVMLNFSGCSGGVAGIRVAKDIAENNPGSRVLLATSETTIIGFRPPSAERPYDLVGVALFGDGAGAMIVGTNPELSIESPLFELHTAMQHFLPDTEKIIDGRLTEEGISFKLGKELPQVIEDNIEGFCSKLMEVAGYSKKDYNKMFWAVHPGGPAILNRMEKKLDLLPEKLNASRRALADYGNASSNTIVYVLEYMLEENKKERKEDQGDEEWGLVLAFGPGITFEGILTRTL
>g23625.t1
MASTSIEEIRQAQRAQGPATILAIGTATPSNCVYQVDYPDYYFRITQSEHKTDLKDKFKRMCEKSMIKKRYMHLTEDILKENPNICAYMAPSLDARQDIVVVEVPKLGKEAASKAIKEWGQPKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNKGARVLVVCSEITAVTFRGPSDSHLDSLVGQALFGDGAAAVIVGADPDTSLERPLFQLVSASQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISRNIDKSLVEAFKPMGISDWNSIFWIAHPGGPAILDQVEAKLGLKQDKLRATRHVLSEYGNMSSACVLFILDEMRKKSIEAGKLTTGEGLEWGVLFGFGPGLTVETVVLHSVPATVN
>g27118.t1
MSKFNKNGTFRRIPTPGKATILSIGKAFPRQVVPQDCLVEGYVRDMKCDDLAIKEKLERLCKTTTVKTRYTVMSKEILEKYPELATEGSPTIKQRLEIANPAVVEMAKEASQACIKEWGRPVGDITHIVYVSSSEIRLPGGDLYLATELGLRSDVGRIMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPIIGTESPFMELNYAVQQFLPGTNNVIDGQLSEEGINFRLGRDLPQKIEDNIEEFCKKLMSKAGLDDFNDLFWAVHPGGPAILNRLESTLKLKTEKLECSRRTLMDFGNVSSNTIFYVMEYMKEELKREGSEEWGLALAFGPGITFEGILIRSL
>g28707.t1
MSRISKNGTSRRAPTPGKATVLSIGKAFPKQVVPQDCLVEGYVRDTKCMDQAIKEKLERLCKTTTVKTRYTVMSKEILDKYPELITEGSPTIKQRLEIANPAVVEMAKEASLACIKNWGRPVDDITHIVYVSSSEIRLPGGDLYLATELGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLLTTSETTILGFRPPNKARPYDLVGAALFGDGAAAVIIGANPVTGAESPFMELNYAVQQFLPGTNNVIDGRLSEEGINFRLGRDLPQKIEENIEAFCKKLMAKAGLDDFNDLFWAVHPGGPAILNRLESTLKLKAGKLECSRRTLMDFGNVSSNTIFYVMEYMREELQRDGSEEWGLALAFGPGITFEGILIRSL
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University