Enzyme
The enzyme catalyses the first committed step in the biosynthesis of flavonoids. It can also act on dihydro-4-coumaroyl-CoA, forming phloretin.
CHS
Enzyme
Chalcone synthase
Enzyme name
EC:2.3.1.74
Entry
Transferases;Acyltransferases;Transferring groups other than aminoacyl groups
Class
malonyl-CoA:4-coumaroyl-CoA malonyltransferase (cyclizing)
Sysname
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO2[RN:R01613]
Reaction
CoA [CPD:C00010];naringenin chalcone [CPD:C06561];CO2 [CPD:C00011]
Product
Species information
Chimonanthus salicifolius
Species name
Chimonanthus salicifolius is a species of flowering plant in the family Calycanthaceae.
Species info
Gene sequence info
Chimonanthus_salicifolius.CHS.fa
Download
>Cs01g02279.t1
MVTVDAIRKAQRAEGPATIMAIGTATPPNAVDQSAYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGA
>Cs01g02280.t1
MMYQQGCFAGGTVVRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAALIVGADPIPGIEKPLFEVVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGISDWNSLFWIAHPGGPAILDQVETKLSLKPGKLRATRHVLSEYGNMSSACVLFILDEMRRKSAEDGLKTTGEGIEWGVLFGFGPGLTVETVVLHSVPTH
>Cs02g01532.t1
MSSTSGPECSPKEPKPGKAIIMALGKAFPHQLVMQEFLVDGYFKNTKCDDPELKQKLTRLCKTTTVKTRYVVMSEEILRKYPELAVEGLPTVKQRLDISNKAVTQMAIEASQACVEKWGRPVSDITHLVYVSSSEARLPGGDLYLAKGLGLSPEGVSQGLRVAKDIAENNPGSRILLATSETTIIGFKPPSADRPYDLVGAALFGDGAGAMIVGTDPILGVETPFFELHSAIQHFLPDTEKTIDGSLTEVGINFKLGRDLPQIIEDHIEGFCTKLMKSIGLNEADYNEMFWAVHPGGPAILNRIEKRLNLLPQKLSASRRALMDYGNASSNTIVYVMEYMIEESLKMKDMGENGPDWGLILAFGPGITFEGILARNLV
>Cs04g01186.t1
MATSPSVEEIRKAQRAEGPANVLAIGTATPSNVVYQADYPDYYFRITKSEHMAELKEKFKRMCDKSMIRKRYMHLTEEILKENPNVCEYMAPSLDARQDMVVVEVPKLGKEAAAKAIKEWAHQAPRPASLRQTPYDVPTRLLLPVAPSSASPRTSPRTMLVPVCSWCARRSRQSLSVGPSDSHLDSLVGQALFGDGAAAVIVGADPDLSIERPLFQLVSATQTILPDSDVGLTFHLLKDVPGLISKNIEKSLVEAFGPLGISDWNSIFWAAHPGGPAILDQVEAKLGLKPEKMRATRHILSEYGNMSSACVLFILDELRKKSLEEGCATTGEGLDWGVLFGFGPGLTVETVVLHSITQNSN
>Cs06g02009.t1
MVTVDEIRKAQRAEGPATILAIGTATPANAVDQSEYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAAKAIKEWGQAKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVVRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAALIVGADPVPGVEKPLFEVASAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGISDWNSLFWIAHPGGPAILDQVESKLALKPEKLRATRHILSEYGNMSSACVLFILDEMRKKSAEEGCKTTGEGIEWGVLFGFGPGLTVETVVLHSVPIH
>Cs06g02012.t1
MFQALFPRTLRRALWRHLSLWAFLTGILYFGSLILVGLPSWTRWRPLALKPEKLRATSNILSEYGNMSSACVLFILDEMRRKSAEEGCKTTGEGIEWGVLFGFGPRLTVETVVLHSVPIH
>Cs06g02011.t1
MAIEMVTTVGETHSVSLATGSAGKQQPVGSCCRRWRADRVSPRNSYLFLGLLSSLFSQRFFQFPTSLALGRRRITMRPAGDKVLILDHATNQSPMRVKSPIFISLLGISEDEYGVPCSGPITLPCQKSMIKKRYMHLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAAKAIKEWGQPKSKITHVIFCTTGGIDMLSADYQLIKLLGLRPSAKDLMMYQQGGFAGGTVIRLAKDLAENNKGARVLVVCSEITVVTFRGPSDTHLDNLVGQTLFGDGAAALIVGADPVPGIEKPLFEVVSTAQTFLPVMTLVSLPLPIDIFFALSQSRRRSHLQ
>Cs08g02286.t1
MVNVDDIRRRQRADGPATIMAIGTATPPNMVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMEPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAALIVGADPVPGVEKPMFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGISDWNSLFWIAHPGGPAILDQVESKLGLKPEKLRATRHVLSEYGNMSSACVLFILDDMRKKSAEEGCKTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
>Cs08g02284.t1
MVNVDDIRRRQRAAGPATIMAIGTATPPNMVDQSTYPDYYFRITNSEHKIELKEKFKRICEKSMIKKRYMHLTEEILKENPNICAYTEPSLDARQDMVVVEVPRLGKEAAAKAIEEWGQPKSKITHLIFYTTSGVDMPGADYQLTKLLGLHPSVKRLMMYQLGCFAGGTVLRLAKDLAENNRGARVLVVCSENTAVTFRDPSDTHVDNLVGQALFGDGAAALIVGADPVPGVEKPMFEIVSAAQTILPDSDGAMDLHLREVGLTFHLRKDVPGLISKNIEKSLVEAFEPLGKSDWNSLFWIAHPGGPAILDQVESKLGLKPEKLRATRHVLSEYGNMASPCVLFILDDMRKKSAEEGCKTTGEGLEWGVLFGFGPGLTVETVVLHSVFA
>Cs10g02450.t1
MTKLETNLVWNYDINHLDLVSNKPSANFRRLSKVGGDQKLISHFSVEEERQMETSPSVEEIRMVQRAQNLATMLVIGMVTPSNVVYQADYPDYYFRITKSKHMTELKEKFRQMFEKSMSQKRYMHLTEDLLKENPNICEYIAPSLDARQDMVVEEVPKLVVSTCPTPTTSSPSSLACVPLSNVSLCTNKVALLVALSSASPRTSPRTTSVHVCLEISAVTFCGPSNTHLDSLVGQALFGDGAIAVIIGADPNLSIERPLFQHVLVAQTILQDSDGAVDGHLHEDGLTFHLLKDMPGLISKNVEKRLVEAKLNLKSEKMRATRHILSEYGNISSASVLLILNKMRKKYLEEGCAMTEEGLDWGVLFGFGLDMIVEIVVLHSFPTTAAH
>Cs10g01734.t1
MQSTDLSENGNHHFASGKPKHTPGKATIMALGKAFPSQLVPQEFLVQGYFRDTKCDDSMIKEKLERLCKNTTVKTRYTVMCKDILDKYPELATEGSPTITQRLDIAHPAVLDMAVRAGLACIEEWGRPATDITHVVYVSSSEIRLPGGDLYLSTQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLVTTSETTILGYRPPNMSRPYDLVGAALFGDGAAAVVVGADPLNGTETPFMELNCAVQQFLPGSHNIIDGRLTEEGINFKLGRDLPQMIEDHIQGFCKMLMEKGSLQEFNDLFWAVHPGGPAILNRLESKLNLRKEKLESSRKALMDYGNVSSNTIFYVIDYMREELKRDGGEEWGLVLAFGPGITIEGILVRNLQ
>Cs10g02557.t1
METSPSVEEIRMVQRAQNLATMLVIGMVTPSNVVYQADYPDYYFRITKSKHMTELKEKFRQMFEKSMSQKRYMHLTEDLLKENPNICEYIAPSLDARQDMVVEEVPKLVVSTCPTPTTSSPSSLACVPLSNVSLCTNKVALLVALSSASPRTSPRTMSVHVCLEISAVTFCGPSNTHLNSLVGQALFGDGAIVVIIGANPNLSIKRPLFQHVLVTQTILQDSDGAVDRHLHEDGLTFHLLKDVLGLISKNVEKSGPAILDQVEAKLNLKSEKMRATRHILSEYGNISSASVLLILSKMRKKYLEEGCATTEEGLDWGVLFEFGLDVIIEIVVLHSFPTTAAH
MVTVDAIRKAQRAEGPATIMAIGTATPPNAVDQSAYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAAKAIKEWGQPKSKITHLVFCTTSGVDMPGA
>Cs01g02280.t1
MMYQQGCFAGGTVVRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAALIVGADPIPGIEKPLFEVVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGISDWNSLFWIAHPGGPAILDQVETKLSLKPGKLRATRHVLSEYGNMSSACVLFILDEMRRKSAEDGLKTTGEGIEWGVLFGFGPGLTVETVVLHSVPTH
>Cs02g01532.t1
MSSTSGPECSPKEPKPGKAIIMALGKAFPHQLVMQEFLVDGYFKNTKCDDPELKQKLTRLCKTTTVKTRYVVMSEEILRKYPELAVEGLPTVKQRLDISNKAVTQMAIEASQACVEKWGRPVSDITHLVYVSSSEARLPGGDLYLAKGLGLSPEGVSQGLRVAKDIAENNPGSRILLATSETTIIGFKPPSADRPYDLVGAALFGDGAGAMIVGTDPILGVETPFFELHSAIQHFLPDTEKTIDGSLTEVGINFKLGRDLPQIIEDHIEGFCTKLMKSIGLNEADYNEMFWAVHPGGPAILNRIEKRLNLLPQKLSASRRALMDYGNASSNTIVYVMEYMIEESLKMKDMGENGPDWGLILAFGPGITFEGILARNLV
>Cs04g01186.t1
MATSPSVEEIRKAQRAEGPANVLAIGTATPSNVVYQADYPDYYFRITKSEHMAELKEKFKRMCDKSMIRKRYMHLTEEILKENPNVCEYMAPSLDARQDMVVVEVPKLGKEAAAKAIKEWAHQAPRPASLRQTPYDVPTRLLLPVAPSSASPRTSPRTMLVPVCSWCARRSRQSLSVGPSDSHLDSLVGQALFGDGAAAVIVGADPDLSIERPLFQLVSATQTILPDSDVGLTFHLLKDVPGLISKNIEKSLVEAFGPLGISDWNSIFWAAHPGGPAILDQVEAKLGLKPEKMRATRHILSEYGNMSSACVLFILDELRKKSLEEGCATTGEGLDWGVLFGFGPGLTVETVVLHSITQNSN
>Cs06g02009.t1
MVTVDEIRKAQRAEGPATILAIGTATPANAVDQSEYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAAKAIKEWGQAKSKITHLVFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVVRLAKDLAENNKGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAALIVGADPVPGVEKPLFEVASAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGISDWNSLFWIAHPGGPAILDQVESKLALKPEKLRATRHILSEYGNMSSACVLFILDEMRKKSAEEGCKTTGEGIEWGVLFGFGPGLTVETVVLHSVPIH
>Cs06g02012.t1
MFQALFPRTLRRALWRHLSLWAFLTGILYFGSLILVGLPSWTRWRPLALKPEKLRATSNILSEYGNMSSACVLFILDEMRRKSAEEGCKTTGEGIEWGVLFGFGPRLTVETVVLHSVPIH
>Cs06g02011.t1
MAIEMVTTVGETHSVSLATGSAGKQQPVGSCCRRWRADRVSPRNSYLFLGLLSSLFSQRFFQFPTSLALGRRRITMRPAGDKVLILDHATNQSPMRVKSPIFISLLGISEDEYGVPCSGPITLPCQKSMIKKRYMHLTEEILKENPNVCAYMAPSLDARQDMVVVEVPKLGKEAAAKAIKEWGQPKSKITHVIFCTTGGIDMLSADYQLIKLLGLRPSAKDLMMYQQGGFAGGTVIRLAKDLAENNKGARVLVVCSEITVVTFRGPSDTHLDNLVGQTLFGDGAAALIVGADPVPGIEKPLFEVVSTAQTFLPVMTLVSLPLPIDIFFALSQSRRRSHLQ
>Cs08g02286.t1
MVNVDDIRRRQRADGPATIMAIGTATPPNMVDQSTYPDYYFRITNSEHKTELKEKFKRMCEKSMIKKRYMHLTEEILKENPNVCAYMEPSLDARQDMVVVEVPRLGKEAAAKAIKEWGQPKSKITHLIFCTTSGVDMPGADYQLTKLLGLRPSVKRLMMYQQGCFAGGTVLRLAKDLAENNRGARVLVVCSEITAVTFRGPSDTHLDSLVGQALFGDGAAALIVGADPVPGVEKPMFEMVSAAQTILPDSDGAIDGHLREVGLTFHLLKDVPGLISKNIEKSLVEAFEPLGISDWNSLFWIAHPGGPAILDQVESKLGLKPEKLRATRHVLSEYGNMSSACVLFILDDMRKKSAEEGCKTTGEGLEWGVLFGFGPGLTVETVVLHSVSA
>Cs08g02284.t1
MVNVDDIRRRQRAAGPATIMAIGTATPPNMVDQSTYPDYYFRITNSEHKIELKEKFKRICEKSMIKKRYMHLTEEILKENPNICAYTEPSLDARQDMVVVEVPRLGKEAAAKAIEEWGQPKSKITHLIFYTTSGVDMPGADYQLTKLLGLHPSVKRLMMYQLGCFAGGTVLRLAKDLAENNRGARVLVVCSENTAVTFRDPSDTHVDNLVGQALFGDGAAALIVGADPVPGVEKPMFEIVSAAQTILPDSDGAMDLHLREVGLTFHLRKDVPGLISKNIEKSLVEAFEPLGKSDWNSLFWIAHPGGPAILDQVESKLGLKPEKLRATRHVLSEYGNMASPCVLFILDDMRKKSAEEGCKTTGEGLEWGVLFGFGPGLTVETVVLHSVFA
>Cs10g02450.t1
MTKLETNLVWNYDINHLDLVSNKPSANFRRLSKVGGDQKLISHFSVEEERQMETSPSVEEIRMVQRAQNLATMLVIGMVTPSNVVYQADYPDYYFRITKSKHMTELKEKFRQMFEKSMSQKRYMHLTEDLLKENPNICEYIAPSLDARQDMVVEEVPKLVVSTCPTPTTSSPSSLACVPLSNVSLCTNKVALLVALSSASPRTSPRTTSVHVCLEISAVTFCGPSNTHLDSLVGQALFGDGAIAVIIGADPNLSIERPLFQHVLVAQTILQDSDGAVDGHLHEDGLTFHLLKDMPGLISKNVEKRLVEAKLNLKSEKMRATRHILSEYGNISSASVLLILNKMRKKYLEEGCAMTEEGLDWGVLFGFGLDMIVEIVVLHSFPTTAAH
>Cs10g01734.t1
MQSTDLSENGNHHFASGKPKHTPGKATIMALGKAFPSQLVPQEFLVQGYFRDTKCDDSMIKEKLERLCKNTTVKTRYTVMCKDILDKYPELATEGSPTITQRLDIAHPAVLDMAVRAGLACIEEWGRPATDITHVVYVSSSEIRLPGGDLYLSTQLGLRSDVGRVMLYFLGCYGGVTGLRVAKDIAENNPGSRVLVTTSETTILGYRPPNMSRPYDLVGAALFGDGAAAVVVGADPLNGTETPFMELNCAVQQFLPGSHNIIDGRLTEEGINFKLGRDLPQMIEDHIQGFCKMLMEKGSLQEFNDLFWAVHPGGPAILNRLESKLNLRKEKLESSRKALMDYGNVSSNTIFYVIDYMREELKRDGGEEWGLVLAFGPGITIEGILVRNLQ
>Cs10g02557.t1
METSPSVEEIRMVQRAQNLATMLVIGMVTPSNVVYQADYPDYYFRITKSKHMTELKEKFRQMFEKSMSQKRYMHLTEDLLKENPNICEYIAPSLDARQDMVVEEVPKLVVSTCPTPTTSSPSSLACVPLSNVSLCTNKVALLVALSSASPRTSPRTMSVHVCLEISAVTFCGPSNTHLNSLVGQALFGDGAIVVIIGANPNLSIKRPLFQHVLVTQTILQDSDGAVDRHLHEDGLTFHLLKDVLGLISKNVEKSGPAILDQVEAKLNLKSEKMRATRHILSEYGNISSASVLLILSKMRKKYLEEGCATTEEGLDWGVLFEFGLDVIIEIVVLHSFPTTAAH
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University