Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Chimonanthus salicifolius
Species name
Chimonanthus salicifolius is a species of flowering plant in the family Calycanthaceae.
Species info
Gene sequence info
Chimonanthus_salicifolius.4CL.fa
Download
>Cs01g01779.t1
MESSKDFIFRSKLPDIYIPNHLPLHSYCFENITQVADRPCLIDGGTGKVYTYAEVELTSRKVAAGLNKLGIKQGDVIMLLLPNSPEFVFAFLGASYRGVMSTTANPFYTPPEVAKQAKACNARLIITQACSVEKVKDLAREEGIMVMCIDSPPDGCKHFSELVEVDEKEMPQVEINPEDVVALPYSSGTTGMPKGVMLTHKSLVTSVAQQVDGENPNLYFHSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEIGSLLELVQKYKVTIAPFVPPIVLAIAKSPLIDNYDVSSIRTIMCGAAPMGKELEDTCGTKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAELKIVDPETGSSLPRNQAGEICIRGSQIMKGYLNDPEATKRTIDKEGWLHTGDIGYVDDDDEIFIVDRLKELIKYKGFQVAPAELEAILITHPNIADAAVVPMKDELAGEVPVAFVVKVNGAEITEEEIKQFVAKQVVFYKRIKRVLFLDSIPKAPSGKILRKDLRARLEAGVPN
>Cs01g00567.t1
MAGRNPASQIPTPSLPSSVDPKSGYCSETKIFHSLRPPVALPRPDLPLSVTAYAISLLPSPVPSNPAFIDSSTGFSISFGDLLHRIHILASNLQTIFPFLSRGQTVAFILSPTSVNVPILYLSLLSLGVVVSPANPISTPSEISHQILLSRPDSVLRHIIHQSHASLSGRPFPPAVPVNQSDMAAILYSSGTTGSVKGVGLTHRNLIALLAGMHELREERKSVTVALFTVPLFHVFGFFMTLRAVAGAETVVLMERFDFTAMLRAVETV
>Cs05g00007.t1
MERSGYGRDGIYRSLRPPLRFPTDPNLSMVSFLFRNHSISDLIALVDAESGDAMTFHQFKSSVAKVSAGLSRLGIKKGDVVLIFAPNSIHFPICFLGIIALGAIATTVNPMYTTSELSKQALDSRACLVFTVPELWPKVSPLALPAVILGPRNAIDTSSVTITYFSDLIAAPPTDLPSVPIKQSETAALLYSSGTTGANKGVVLTHRNFITAALMATADQETDGEPRNTFLCFLPMFHIFGLCILTYAQLQRGNCVVVMSRFDMDVVLRSIEKYRVTYLFVVPPVMIALAKQNALNKYDLSSLKRLGSGAAPLGKDIMEECSKNFPQAVVVQGYGLTESCGIVSLDNPNEGLRHTGSTGGLVAGVESKIISVDKMKALAPNQLGEIWIRGPNMMQGYFNNLQATKLTIDKQGWVHTGDLGYFDNEGRLYVVDRIKELIKYKGFQIAPAELEALLLSHPEIIDAVVIPFPDAEAGEVPIAYVVRSSKSSLAEDDVKEFIAKQVAPFKRLRRVTFVNSVPKSASGKILRRELIEKVRSKM
>Cs05g02286.t1
MASGYRTIGERQNCHSQQMQMNKHNLYLPFQTLRDVQNDQFTSFFSPKTGIYTSKHASIQLPNDPFLDVVSFIFSHKHRGISALVDSPSGSIISYTQLPEFVKSVASGLNEFGLRQGQMVLLLLPNTIYFPIIYLAVISLGAIVTAMTPLSSTAEIKKRMDECNACLVFSVLECVKKMEEFGVPVVVVPEGGSIDMCSSVSSSSSFSRLMSSNPKFAPRPIIKQSDTAAILYSSGTSGVSKGVVITHGNLIAAIVLFIGFGASQLGYPPGWENAPTIVVMRRFNMDELARAIDRFGVTHIPVVPPLLAALVRTKHASSSDFSSLKQVTCGAAPLSNKAIQEFLENFPHVDFIQGYGMTESTAVGTFGFNTEKIRKYTSVGLLAPNMEARVVDCDTGSNLPPGRGGELWLRGPGIMKGYLNDKGEALLTVDKEGWLHTGDIVHFDEDGYLYVVDRLKEMIKYKGFQIAPADLEDVIISHPDIIDVAVSASTNENLEEIPVAFVVRRPGSELSPTNIINYVSAKAAPYKKVRKVVFINSIPRSPAGKIFRRQLRNFVVPIDQNISKA
>Cs07g00324.t1
MESAKDYIYTSKLPNIEIPNHLPLHSYCFQNIDLIANRPCLIDGATNKVYTYQEVELTARRVATGLNEIGIQQGQVIMLMLPNSLEFVFAFLGASYRGAMATTANPFYTPAEILKQAKASNARLIITQACYVDKVTDLARENHVMVMCIDSPPDGCLHFSSLLEADESNMPEVDIAPDDVVALPYSSGTTGLPKGVMLTHKGLVTSLAQQVDGANPNLYFHKEDVILCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFDIGALLELVQRYKVTIAPFVPPIVLAIAKSPAVDNYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPETGASLPRNQPGEICIRGSQIMKGYLNDPEATSGTIDKDGWLHTGDVGLVDDDDEIFIVDRLKEIIKYKGFQVAPAELEAMLINHQNIADAAVVSMKDDLAGEVPVSFVVKSNGSVISEEDIKKYIAKQVVFYKRIHKVFFLDSIPKAPSGKILRKELRARLAAGLAN
>Cs07g00429.t1
MGEQPQNSKEEYIFQSNLPAVPVPENQTLPEFVLQGAELYADKVALADIITGKEYTYGQLHSDTSRFAKALRSLGLRKGCVVVVVLPNVVEYVAITLGIMAAGGVFSGSNPQGHASEIRKQVEDSEAKLIVTNGAVYEKVKEVGVPVIVVGHDQECVGSAIRWEDLLAAADRAGPDTSKEELVQHTDLCALPYSSGTTGASKGVMLTHRNLVANLCSTLFSAGSDIVGKITVLGLMPFFHIYGITGICCATIKNKGKVIVMGRFDLRTFMNALITHEVNFAPIVPPIILALVKNPIVDEFDLTKLNLKAVMTAAAPLAPDLRVAFETKFPGAYGLTEHSCITLTHGDPKLGHGISKKNSVGFILPNLEVKFIDPETGLSLPRNTPGELCVRSQCVMLGYYKNKEETDRTIDSNGWLHTGDVGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLSHPSVHDAAVIPLPDEEAGEIPAACVVMNKNAKETEEEIMKYVASNVATYKQVRVLKFVDTIPKSPSGKIMRRLLRDNIMKRMGNN
>Cs07g00269.t1
MESAKDYIYTSKLPNIEIPNHLPLHSYCFQNIDLIANRPCLIDGATNKVYTYQEVELTARRVATGLNEIGIQQGQVIMLMLPNSVEFVFAFLGASYRGAMATTANPFYTPAEILKQAKASNARLIITQACYVDKVTDLARENDVMVMCIDSPPDGCLHFSSLLEADESNMPEVDIAPDDVVALPYSSGTTGLPKGVMLTHKGLVTSLAQQVDGANPNLYFHKEDVILCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFDIGALLELVQRYKVTIAPFVPPIVLAIAKSPAVDNYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPETGASLPRNQPGEICIRGSQIMKGYLNDPEATSGTIDKDGWLHTGDVGLVDDDDEIFIVDRLKEIIKYKGFQVAPAELEAMLINHQNIADAAVVSMKDDLAGEVPVSFVVKSNGSVISEEDIKKYIAEQVVFYKRIHKVFFLDSIPKAPSGKILRKELRARLAN
>Cs10g01503.t1
MLSVASPETQTQIPSTTPPPENPPPETFIFRSKLPEIPISNHLPLHTYCFEKIAEFPDAPCLISGSSGRVYTFAETHLICQKSVAGLSKLGIEKGDVIMVLLQNSPEFVFSFMGASMIGAITTAANPFCTPAEIFKQFTASNAKLIITQSQYIDKLRNAGEKFPKIGEDFKVITVDDPPESCLHFSVISDADERDVPTVSIDADDPVALPFSSGTTGLPKGVILTHKSLISSVAQQVDGENPNLYLTTDDVVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGTLLDLIQRHRVSVAAVVPPLVLALAKNPIVENFDLSSIRIVLSGAAPLGKELEEALRTRVPQAIFGQGYGMTEAGPVLSMCSGFAKQPFPTKSGSCGTVVRNADLKIIDPETGISLKHNQSGEICIRGPQIMKGYLNDPDATASTIDAEGWLHTGDIGYVDDDEEVFIVDRVKELIKFKGFQVPPAELESLLVSHPSIADAAVVPQKDDVAGEVPVAFVVRSNGFEVTEEAIKEFIAKQVVFYKRLYKVYFVHAIPKSASGKILRKDLRAKLATTSVS
>Cs10g02733.t1
MGVLLPVNRFTATLLHVHTYPPFLHSLALIVPPSFSLSSSHFFRIVVLASGSLSKLLYKYWFSLSSEEISTTARMLSLASHETQSEIPPPTQAPTNPPSETFIFRSKLPDIAISNNLPIHTYCFEKIAEFSDVPCLFSSLSGKTYTYAETHLICQKSAAGLSKLGIKKGDVIMLLLQNSPEFVFSFMGASMIGAITTTGNPFCTPVEIFKQFTASRAKLIITQAQYANKLREVGDTLPKVGEDVIVITVDDPPEECMHFSVISNADEGDIPSVEIDPDDAVALPFSSGTTGLPKGVMLTHKNLISNVAQQVDGENPNLYLTPQDVVLCVLPLFHIYSLNSVLLCSLRVGAGILLMPKFEIGALLELIQRYRVSVAAVVPPLVLALAKNPMVANFDLSSIRIILSGAAPLGKELEEALRSRVPKAIFGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAEMKVIDLETGLSLKHNIPGEICIRGPQIMKGYLNDADSTASTIDVEGWLHTGDIGYVDDNEEVFIVDRVKELIKFKGFQVPPAEIEALLISHPSIADAAVVPQKDEVAGEVPVAFVVRSGGFDLTEEHVKEFIAKQVVFYKRLHKVYFVHAIPKSAAGKILRKELRAKLATTHQS
>Cs10g00037.t1
MRETCKVYSLVDGLLQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVGDEKSILLYIGKELNPSMNVSVLNKCTDVKPLLETFVIADQPPGIADNALVDRLSLHADLLQCPHVGPSKSLLAAPLFFVFNSAHHQVPTPLS
MESSKDFIFRSKLPDIYIPNHLPLHSYCFENITQVADRPCLIDGGTGKVYTYAEVELTSRKVAAGLNKLGIKQGDVIMLLLPNSPEFVFAFLGASYRGVMSTTANPFYTPPEVAKQAKACNARLIITQACSVEKVKDLAREEGIMVMCIDSPPDGCKHFSELVEVDEKEMPQVEINPEDVVALPYSSGTTGMPKGVMLTHKSLVTSVAQQVDGENPNLYFHSDDVLLCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFEIGSLLELVQKYKVTIAPFVPPIVLAIAKSPLIDNYDVSSIRTIMCGAAPMGKELEDTCGTKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGACGTVVRNAELKIVDPETGSSLPRNQAGEICIRGSQIMKGYLNDPEATKRTIDKEGWLHTGDIGYVDDDDEIFIVDRLKELIKYKGFQVAPAELEAILITHPNIADAAVVPMKDELAGEVPVAFVVKVNGAEITEEEIKQFVAKQVVFYKRIKRVLFLDSIPKAPSGKILRKDLRARLEAGVPN
>Cs01g00567.t1
MAGRNPASQIPTPSLPSSVDPKSGYCSETKIFHSLRPPVALPRPDLPLSVTAYAISLLPSPVPSNPAFIDSSTGFSISFGDLLHRIHILASNLQTIFPFLSRGQTVAFILSPTSVNVPILYLSLLSLGVVVSPANPISTPSEISHQILLSRPDSVLRHIIHQSHASLSGRPFPPAVPVNQSDMAAILYSSGTTGSVKGVGLTHRNLIALLAGMHELREERKSVTVALFTVPLFHVFGFFMTLRAVAGAETVVLMERFDFTAMLRAVETV
>Cs05g00007.t1
MERSGYGRDGIYRSLRPPLRFPTDPNLSMVSFLFRNHSISDLIALVDAESGDAMTFHQFKSSVAKVSAGLSRLGIKKGDVVLIFAPNSIHFPICFLGIIALGAIATTVNPMYTTSELSKQALDSRACLVFTVPELWPKVSPLALPAVILGPRNAIDTSSVTITYFSDLIAAPPTDLPSVPIKQSETAALLYSSGTTGANKGVVLTHRNFITAALMATADQETDGEPRNTFLCFLPMFHIFGLCILTYAQLQRGNCVVVMSRFDMDVVLRSIEKYRVTYLFVVPPVMIALAKQNALNKYDLSSLKRLGSGAAPLGKDIMEECSKNFPQAVVVQGYGLTESCGIVSLDNPNEGLRHTGSTGGLVAGVESKIISVDKMKALAPNQLGEIWIRGPNMMQGYFNNLQATKLTIDKQGWVHTGDLGYFDNEGRLYVVDRIKELIKYKGFQIAPAELEALLLSHPEIIDAVVIPFPDAEAGEVPIAYVVRSSKSSLAEDDVKEFIAKQVAPFKRLRRVTFVNSVPKSASGKILRRELIEKVRSKM
>Cs05g02286.t1
MASGYRTIGERQNCHSQQMQMNKHNLYLPFQTLRDVQNDQFTSFFSPKTGIYTSKHASIQLPNDPFLDVVSFIFSHKHRGISALVDSPSGSIISYTQLPEFVKSVASGLNEFGLRQGQMVLLLLPNTIYFPIIYLAVISLGAIVTAMTPLSSTAEIKKRMDECNACLVFSVLECVKKMEEFGVPVVVVPEGGSIDMCSSVSSSSSFSRLMSSNPKFAPRPIIKQSDTAAILYSSGTSGVSKGVVITHGNLIAAIVLFIGFGASQLGYPPGWENAPTIVVMRRFNMDELARAIDRFGVTHIPVVPPLLAALVRTKHASSSDFSSLKQVTCGAAPLSNKAIQEFLENFPHVDFIQGYGMTESTAVGTFGFNTEKIRKYTSVGLLAPNMEARVVDCDTGSNLPPGRGGELWLRGPGIMKGYLNDKGEALLTVDKEGWLHTGDIVHFDEDGYLYVVDRLKEMIKYKGFQIAPADLEDVIISHPDIIDVAVSASTNENLEEIPVAFVVRRPGSELSPTNIINYVSAKAAPYKKVRKVVFINSIPRSPAGKIFRRQLRNFVVPIDQNISKA
>Cs07g00324.t1
MESAKDYIYTSKLPNIEIPNHLPLHSYCFQNIDLIANRPCLIDGATNKVYTYQEVELTARRVATGLNEIGIQQGQVIMLMLPNSLEFVFAFLGASYRGAMATTANPFYTPAEILKQAKASNARLIITQACYVDKVTDLARENHVMVMCIDSPPDGCLHFSSLLEADESNMPEVDIAPDDVVALPYSSGTTGLPKGVMLTHKGLVTSLAQQVDGANPNLYFHKEDVILCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFDIGALLELVQRYKVTIAPFVPPIVLAIAKSPAVDNYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPETGASLPRNQPGEICIRGSQIMKGYLNDPEATSGTIDKDGWLHTGDVGLVDDDDEIFIVDRLKEIIKYKGFQVAPAELEAMLINHQNIADAAVVSMKDDLAGEVPVSFVVKSNGSVISEEDIKKYIAKQVVFYKRIHKVFFLDSIPKAPSGKILRKELRARLAAGLAN
>Cs07g00429.t1
MGEQPQNSKEEYIFQSNLPAVPVPENQTLPEFVLQGAELYADKVALADIITGKEYTYGQLHSDTSRFAKALRSLGLRKGCVVVVVLPNVVEYVAITLGIMAAGGVFSGSNPQGHASEIRKQVEDSEAKLIVTNGAVYEKVKEVGVPVIVVGHDQECVGSAIRWEDLLAAADRAGPDTSKEELVQHTDLCALPYSSGTTGASKGVMLTHRNLVANLCSTLFSAGSDIVGKITVLGLMPFFHIYGITGICCATIKNKGKVIVMGRFDLRTFMNALITHEVNFAPIVPPIILALVKNPIVDEFDLTKLNLKAVMTAAAPLAPDLRVAFETKFPGAYGLTEHSCITLTHGDPKLGHGISKKNSVGFILPNLEVKFIDPETGLSLPRNTPGELCVRSQCVMLGYYKNKEETDRTIDSNGWLHTGDVGYIDDDGDIFIVDRIKELIKYKGFQVAPAELEAILLSHPSVHDAAVIPLPDEEAGEIPAACVVMNKNAKETEEEIMKYVASNVATYKQVRVLKFVDTIPKSPSGKIMRRLLRDNIMKRMGNN
>Cs07g00269.t1
MESAKDYIYTSKLPNIEIPNHLPLHSYCFQNIDLIANRPCLIDGATNKVYTYQEVELTARRVATGLNEIGIQQGQVIMLMLPNSVEFVFAFLGASYRGAMATTANPFYTPAEILKQAKASNARLIITQACYVDKVTDLARENDVMVMCIDSPPDGCLHFSSLLEADESNMPEVDIAPDDVVALPYSSGTTGLPKGVMLTHKGLVTSLAQQVDGANPNLYFHKEDVILCVLPLFHIYSLNSVLLCGLRAGAAILIMQKFDIGALLELVQRYKVTIAPFVPPIVLAIAKSPAVDNYDLSSIRTVMSGAAPMGKELEDTVRAKLPNAKLGQGYGMTEAGPVLSMCLAFAKEPFEIKSGSCGTVVRNAEMKIVDPETGASLPRNQPGEICIRGSQIMKGYLNDPEATSGTIDKDGWLHTGDVGLVDDDDEIFIVDRLKEIIKYKGFQVAPAELEAMLINHQNIADAAVVSMKDDLAGEVPVSFVVKSNGSVISEEDIKKYIAEQVVFYKRIHKVFFLDSIPKAPSGKILRKELRARLAN
>Cs10g01503.t1
MLSVASPETQTQIPSTTPPPENPPPETFIFRSKLPEIPISNHLPLHTYCFEKIAEFPDAPCLISGSSGRVYTFAETHLICQKSVAGLSKLGIEKGDVIMVLLQNSPEFVFSFMGASMIGAITTAANPFCTPAEIFKQFTASNAKLIITQSQYIDKLRNAGEKFPKIGEDFKVITVDDPPESCLHFSVISDADERDVPTVSIDADDPVALPFSSGTTGLPKGVILTHKSLISSVAQQVDGENPNLYLTTDDVVLCVLPLFHIYSLNSVLLCSLRAGAGVLLMQKFEIGTLLDLIQRHRVSVAAVVPPLVLALAKNPIVENFDLSSIRIVLSGAAPLGKELEEALRTRVPQAIFGQGYGMTEAGPVLSMCSGFAKQPFPTKSGSCGTVVRNADLKIIDPETGISLKHNQSGEICIRGPQIMKGYLNDPDATASTIDAEGWLHTGDIGYVDDDEEVFIVDRVKELIKFKGFQVPPAELESLLVSHPSIADAAVVPQKDDVAGEVPVAFVVRSNGFEVTEEAIKEFIAKQVVFYKRLYKVYFVHAIPKSASGKILRKDLRAKLATTSVS
>Cs10g02733.t1
MGVLLPVNRFTATLLHVHTYPPFLHSLALIVPPSFSLSSSHFFRIVVLASGSLSKLLYKYWFSLSSEEISTTARMLSLASHETQSEIPPPTQAPTNPPSETFIFRSKLPDIAISNNLPIHTYCFEKIAEFSDVPCLFSSLSGKTYTYAETHLICQKSAAGLSKLGIKKGDVIMLLLQNSPEFVFSFMGASMIGAITTTGNPFCTPVEIFKQFTASRAKLIITQAQYANKLREVGDTLPKVGEDVIVITVDDPPEECMHFSVISNADEGDIPSVEIDPDDAVALPFSSGTTGLPKGVMLTHKNLISNVAQQVDGENPNLYLTPQDVVLCVLPLFHIYSLNSVLLCSLRVGAGILLMPKFEIGALLELIQRYRVSVAAVVPPLVLALAKNPMVANFDLSSIRIILSGAAPLGKELEEALRSRVPKAIFGQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVRNAEMKVIDLETGLSLKHNIPGEICIRGPQIMKGYLNDADSTASTIDVEGWLHTGDIGYVDDNEEVFIVDRVKELIKFKGFQVPPAEIEALLISHPSIADAAVVPQKDEVAGEVPVAFVVRSGGFDLTEEHVKEFIAKQVVFYKRLHKVYFVHAIPKSAAGKILRKELRAKLATTHQS
>Cs10g00037.t1
MRETCKVYSLVDGLLQGYGMTEAGPVLSMCLGFAKQPFPTKSGSCGTVVGDEKSILLYIGKELNPSMNVSVLNKCTDVKPLLETFVIADQPPGIADNALVDRLSLHADLLQCPHVGPSKSLLAAPLFFVFNSAHHQVPTPLS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University