Enzyme
4CL
Enzyme
4-coumarate:CoA ligase
Enzyme name
EC:6.2.1.12
Entry
Ligases;Forming carbon-sulfur bonds;Acid-thiol ligases
Class
4-coumarate:CoA ligase (AMP-forming)
Sysname
ATP + 4-coumarate + CoA = AMP + diphosphate + 4-coumaroyl-CoA [RN:R01616]
Reaction
AMP [CPD:C00020];diphosphate [CPD:C00013];4-coumaroyl-CoA [CPD:C00223]
Product
Species information
Cercis canadensis
Species name
Cercis canadensis is a species of eudicot in the family Fabaceae (pea family).
Species info
Gene sequence info
Cercis_canadensis.4CL.fa
Download
>Cerca10S12453
MQRSGFGRDGIYRSLRPSIVIPKDPNLSLVSFLFRNISSYPNKPALIDADSSETLSFAQLKSIVVKVSHALLHLGIKKNDVVLLFAPNSIQFPICFFGVVAIGAIASTANPIYTVAELSKQVKDSNPKLVITVPELLDKVKDFNLPAVILGSESPSLVAFNSKITTFNGLLELAGSPTEFPASHVKQSDTAALLYSSGTTGVSKGVILTHSNFIASGLMITLDDELTGQMHDVFICVLPMFHVFGMAVIMYAQLQRGNAVVSLKKFDFEMLLKAVEKYRVTNLWVVPPIILALAKNSLVKKYNLSSLRQVGSGAAPLGKELMQECARNLPHVEVLQGYGMTETCGIVSVENSRFGIRHTGSTGLLVSGVEAQIVSVDTMKPLPPGQLGEIWVRGPNMMQGYYNNPQATRLTIDDKGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEEDVQKFIADQVAPFKRLRRVTFINSVPKTASGKILRRELIDKARSKI
>Cerca5S27321
MGSETETKQQKEFIFRSKLDDIYIPKHLPLHSYVFDNLSAFGSRPCLINAVTGDIYSYYDVELTARRVASGLNKLGIKQGEVIMILLPNSPEFVFSFLGASYRGAITTAANPFFTPAEIAKQAKASQTKLLITQASYYDKVKDLDVKLMFVDSPPQGHLHFSELSEANENEMVEVQINPDDVLALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYYHSEDVILCVLPLFHIYSLNSVFLCGLRAKAAILLMPKFEINALLGLIQKYRVTIAPVVPPIVLAISKSPDLHKYDLSSIRVLKSGGAPLGKELEDTLRAKFPNAKLGQGYGMTEAGPVLTMSLAFAKEAMEVKAGACGSVVRNAEMKILDPETGHSLPRNHPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDVGYIDDDDELYIVDRLKELIKYKGFQVAPAELEALLLSHPKISDAAVVPMKDEAAGEVPVAFVVRSNGNTDTTEDEVKQFISKQVVFYKRINRVFFIDAIPKSPSGKILRKELRAKLAAAVPPN
>Cerca27S20041
MAKSFDPKSLTYSSPRPPLHLPTERNLSLTTFLFQSSSSFAHTLALVDADSGESLTFHQLHIYVSKLAHALLHIGINKGEVVFIFAPNSIHYFICFLAVVAIGAIATTCNPLYTFFELSKQVKDSNPKIAITVPEFFDKIEPLNLPSIMLGPSKSTNLSSNSKSKIWHYADLIGMSNGISNLPAENNVTQSDVAALLYSSGTTGRSKGVILTHGNFISQSLMATADQDRNGEIKNVFLCFLPMFHVFGLAIISYSQLRRGNTVVSMKRFELKKALEAVEKFKVTYLYVAPPVMIELLKQSDVVSKYDLSSLKQIAGGAAPLGKDVMQDCAKILPKVEIIQGYGMTETCGIISLENPKEGSRLTGSTGKLLEGLESRIVSLDTGKPLPPNQSGEIWIRGPTVMQGYFNNPEATKLTIDDDGWMRTGDLGYFDQEGQLFVVDRIKELIKCNGFQVAPAELEDLLVSHPEILDAGVIPSPDTKAGEVPVAYVVRSPNSLLTEDEIKKFIAEQVAPYKRLRRVTFIEKIPKSTTGKILRKDLMKIDQQMTSKL
>Cerca148S14738
MGTCVENLTQGEEEHIFRSRYSAVPVPKNVTLPEFVLHNAELYGDKVAFVEAVTGKRITYSEVVRDTERFSKALRSLGLRKGNVVLVVLPNVAEYAIIALGIMAAGGVFSGANPTAHASEIKKQAEAADAKLIITNDLTYGKVKGLELPIIVVADEPIEDAMNWKKLLDAADRAGDKLVNEPVQQNDLCAMPFSSGTTGMSKGVMLTHQNLVANLCSTLFGVAPEMVGQVTTLGLIPFFHIYGITGICCATLRNKGKVVVMGRFELRTFLNALITHEVMFAPIVPPIILNLVKNPIVDEFDLSKLKLHAIMTAAAPLAPELLTAFENKFPGVVVQEAYGLTEHSCITLTHVHKDFGNSKRSSVGFILPNLEVKFIDPDTGRSLPKNTPGELCVRSQCVMQGYYKNEGETAQTIDKNGWLHTGDIGFIDDEDSVFIVDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPGASVVMSPGARESEEDIIHYVASNVANYKKVRVVHFVEAIPKSPSGKIMRRLIKERMVEKMSPSSTTKSKTPIA
>Cerca150S15015
MEGMGQDQEFIFRSKLGDIYIPTHLPLHSYTFENISQFKDRPCLINGNTGETFTYADVEFRARKVATGLNNLGIQQGDVIMLLLQNCPQFVLAFLGASYLGAIITTANPFYTPAEVAKQAIASKSKLIITQASYVEKVSDFAKHNHIKVMCIDSPPEPELDEEGLLHFSDLTEANEGDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHKSLVTSVAQQVDGDNPNLYYHKNDVILCVLPLFHIYSLNTVLLCGLRVGAAILLMQKFEIVTLLELVQKYKVTIAPFVPPIVLAIAKSPQVQRYDLSSIRILMSGAAPMGKELEDAVKAKLPNATLGQGYGMTEAGPVLSMSLGFAKEPFKIKSGACGSVVRNAEMKIVDPDTGASLARNQPGEICMRGTQIMIGYLNDPVATERTIDKQGWLHTGDIGFIDLDDEIFIVDRLKELIKYKGFQVAPAELEAMLISHPNIADAAVVPMKDEAAGEVPVAFVVKSNGSKISEDDIKQYISEQVVFYKRINRVFFVDLIPKGPSGKILRKDLRARLAAGLAF
>Cerca280S20125
MITVAPSVDTQNPEFSSPKNAPEQNPSPPKNTHIFKSKLPDIPISNHLPLHTYCFEHLSEISDRPCLIVGSTGRIYTFGETHLLSRKIAAGLANLGIKKGDVIMILLQNCAEFVLSFIAASMIGAVATTANPFYTSAEIFKQFESSECKLIITQSLYVDKLRENEDNHPKIGDDFKVITVDDPPENCLHFSVISEADESELPEVEIDPNDPVALPFSSGTTGLPKGVILTHKSLTTSVAQQVDGENPNLYLTQDDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMPKFEIGSLLELIQQHRVSVAMVVPPLVLALAKNPMVADFDLSSIRLVLSGAAPLGKELEDALRSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQSFPTKSGSCGTVVRNAELKVVDPDTGSSLGYNQPGEICIRGQQIMKGYLNDEKATEATIDVEGWLHTGDIGYVDIENDEIFIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDDAAGELPVAFVVRSNGFDLTEETVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAASNEMS
MQRSGFGRDGIYRSLRPSIVIPKDPNLSLVSFLFRNISSYPNKPALIDADSSETLSFAQLKSIVVKVSHALLHLGIKKNDVVLLFAPNSIQFPICFFGVVAIGAIASTANPIYTVAELSKQVKDSNPKLVITVPELLDKVKDFNLPAVILGSESPSLVAFNSKITTFNGLLELAGSPTEFPASHVKQSDTAALLYSSGTTGVSKGVILTHSNFIASGLMITLDDELTGQMHDVFICVLPMFHVFGMAVIMYAQLQRGNAVVSLKKFDFEMLLKAVEKYRVTNLWVVPPIILALAKNSLVKKYNLSSLRQVGSGAAPLGKELMQECARNLPHVEVLQGYGMTETCGIVSVENSRFGIRHTGSTGLLVSGVEAQIVSVDTMKPLPPGQLGEIWVRGPNMMQGYYNNPQATRLTIDDKGWVHTGDLGYFDEEGQLFVVDRIKELIKYKGFQVAPAELEGLLVSHPEILDAVVIPYPDAEAGEVPVAYVVRSPNSSLTEEDVQKFIADQVAPFKRLRRVTFINSVPKTASGKILRRELIDKARSKI
>Cerca5S27321
MGSETETKQQKEFIFRSKLDDIYIPKHLPLHSYVFDNLSAFGSRPCLINAVTGDIYSYYDVELTARRVASGLNKLGIKQGEVIMILLPNSPEFVFSFLGASYRGAITTAANPFFTPAEIAKQAKASQTKLLITQASYYDKVKDLDVKLMFVDSPPQGHLHFSELSEANENEMVEVQINPDDVLALPYSSGTTGLPKGVMLTHKGLVTSIAQQVDGENPNLYYHSEDVILCVLPLFHIYSLNSVFLCGLRAKAAILLMPKFEINALLGLIQKYRVTIAPVVPPIVLAISKSPDLHKYDLSSIRVLKSGGAPLGKELEDTLRAKFPNAKLGQGYGMTEAGPVLTMSLAFAKEAMEVKAGACGSVVRNAEMKILDPETGHSLPRNHPGEICIRGDQIMKGYLNDPEATERTIDKEGWLHTGDVGYIDDDDELYIVDRLKELIKYKGFQVAPAELEALLLSHPKISDAAVVPMKDEAAGEVPVAFVVRSNGNTDTTEDEVKQFISKQVVFYKRINRVFFIDAIPKSPSGKILRKELRAKLAAAVPPN
>Cerca27S20041
MAKSFDPKSLTYSSPRPPLHLPTERNLSLTTFLFQSSSSFAHTLALVDADSGESLTFHQLHIYVSKLAHALLHIGINKGEVVFIFAPNSIHYFICFLAVVAIGAIATTCNPLYTFFELSKQVKDSNPKIAITVPEFFDKIEPLNLPSIMLGPSKSTNLSSNSKSKIWHYADLIGMSNGISNLPAENNVTQSDVAALLYSSGTTGRSKGVILTHGNFISQSLMATADQDRNGEIKNVFLCFLPMFHVFGLAIISYSQLRRGNTVVSMKRFELKKALEAVEKFKVTYLYVAPPVMIELLKQSDVVSKYDLSSLKQIAGGAAPLGKDVMQDCAKILPKVEIIQGYGMTETCGIISLENPKEGSRLTGSTGKLLEGLESRIVSLDTGKPLPPNQSGEIWIRGPTVMQGYFNNPEATKLTIDDDGWMRTGDLGYFDQEGQLFVVDRIKELIKCNGFQVAPAELEDLLVSHPEILDAGVIPSPDTKAGEVPVAYVVRSPNSLLTEDEIKKFIAEQVAPYKRLRRVTFIEKIPKSTTGKILRKDLMKIDQQMTSKL
>Cerca148S14738
MGTCVENLTQGEEEHIFRSRYSAVPVPKNVTLPEFVLHNAELYGDKVAFVEAVTGKRITYSEVVRDTERFSKALRSLGLRKGNVVLVVLPNVAEYAIIALGIMAAGGVFSGANPTAHASEIKKQAEAADAKLIITNDLTYGKVKGLELPIIVVADEPIEDAMNWKKLLDAADRAGDKLVNEPVQQNDLCAMPFSSGTTGMSKGVMLTHQNLVANLCSTLFGVAPEMVGQVTTLGLIPFFHIYGITGICCATLRNKGKVVVMGRFELRTFLNALITHEVMFAPIVPPIILNLVKNPIVDEFDLSKLKLHAIMTAAAPLAPELLTAFENKFPGVVVQEAYGLTEHSCITLTHVHKDFGNSKRSSVGFILPNLEVKFIDPDTGRSLPKNTPGELCVRSQCVMQGYYKNEGETAQTIDKNGWLHTGDIGFIDDEDSVFIVDRIKELIKYKGFQVAPAELEAILLSHSSVEDAAVVPLPDEEAGEIPGASVVMSPGARESEEDIIHYVASNVANYKKVRVVHFVEAIPKSPSGKIMRRLIKERMVEKMSPSSTTKSKTPIA
>Cerca150S15015
MEGMGQDQEFIFRSKLGDIYIPTHLPLHSYTFENISQFKDRPCLINGNTGETFTYADVEFRARKVATGLNNLGIQQGDVIMLLLQNCPQFVLAFLGASYLGAIITTANPFYTPAEVAKQAIASKSKLIITQASYVEKVSDFAKHNHIKVMCIDSPPEPELDEEGLLHFSDLTEANEGDIPAVKINPDDVVALPYSSGTTGLPKGVMLTHKSLVTSVAQQVDGDNPNLYYHKNDVILCVLPLFHIYSLNTVLLCGLRVGAAILLMQKFEIVTLLELVQKYKVTIAPFVPPIVLAIAKSPQVQRYDLSSIRILMSGAAPMGKELEDAVKAKLPNATLGQGYGMTEAGPVLSMSLGFAKEPFKIKSGACGSVVRNAEMKIVDPDTGASLARNQPGEICMRGTQIMIGYLNDPVATERTIDKQGWLHTGDIGFIDLDDEIFIVDRLKELIKYKGFQVAPAELEAMLISHPNIADAAVVPMKDEAAGEVPVAFVVKSNGSKISEDDIKQYISEQVVFYKRINRVFFVDLIPKGPSGKILRKDLRARLAAGLAF
>Cerca280S20125
MITVAPSVDTQNPEFSSPKNAPEQNPSPPKNTHIFKSKLPDIPISNHLPLHTYCFEHLSEISDRPCLIVGSTGRIYTFGETHLLSRKIAAGLANLGIKKGDVIMILLQNCAEFVLSFIAASMIGAVATTANPFYTSAEIFKQFESSECKLIITQSLYVDKLRENEDNHPKIGDDFKVITVDDPPENCLHFSVISEADESELPEVEIDPNDPVALPFSSGTTGLPKGVILTHKSLTTSVAQQVDGENPNLYLTQDDVLLCVLPLFHIFSLNSVLLCALRAGSAVLLMPKFEIGSLLELIQQHRVSVAMVVPPLVLALAKNPMVADFDLSSIRLVLSGAAPLGKELEDALRSRVPQAVLGQGYGMTEAGPVLSMCLGFAKQSFPTKSGSCGTVVRNAELKVVDPDTGSSLGYNQPGEICIRGQQIMKGYLNDEKATEATIDVEGWLHTGDIGYVDIENDEIFIVDRVKELIKFKGFQVPPAELEALLVSHPSIADAAVVPQKDDAAGELPVAFVVRSNGFDLTEETVKEFIAKQVVFYKRLHKVYFVHAIPKSPSGKILRKDLRAKLAASNEMS
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University