Enzyme
Specific for quercetin. Related enzymes bring about the 3-O-methylation of other flavonols, such as galangin and kaempferol.
COMT
Enzyme
Flavone 3'-O-methyltransferase
Enzyme name
EC:2.1.1.76
Entry
Transferases;Transferring one-carbon groups;Methyltransferases
Class
S-adenosyl-L-methionine:3,5,7,3',4'-pentahydroxyflavone 3-O-methyltransferase
Sysname
S-adenosyl-L-methionine + 3,5,7,3',4'-pentahydroxyflavone = S-adenosyl-L-homocysteine + 3-methoxy-5,7,3',4'-tetrahydroxyflavone [RN:R02157]
Reaction
S-adenosyl-L-homocysteine [CPD:C00021];3-methoxy-5,7,3',4'-tetrahydroxyflavone [CPD:C04443]
Product
Species information
Ceratophyllum demersum
Species name
Hornwort (Ceratophyllum demersum) is a species of flowering plant in the family Ceratophyllaceae.
Species info
Gene sequence info
Ceratophyllum_demersum.COMT.fa
Download
>gene_prefix09427.mRNA1
MKWILHDWSDEHCLKFLANCWKSLPESGKVIIVECILPVYPENNLAANGVFNVDMIMLAQNPGGKERTEKDYKNLAKKAVVWRRFQENNNLIPRLNPSLEGFLDPIIEDQTTFHPMLQQIQSPFLDEQNIHSFLNLKQSQKSWMKIHKTVPEINNVQALETESCITNTNNPQSPVKSEKEEIGGEMFIPKQQSKRGSPQDRQHKRKRNNRLKSMKNREEVENQRMTHITVERNRRKLMNDHLAALRSLMPPSFVQRGDQASIIGGAINFVKELEQMLQSLQAQKHKQRLKEDNIEHPFHGFFTSPQFSTYSNQSAHKCVAKTRRTDFREQSKLALVDLEVTMAETHVNLKVLLRKNSRQLLRSIIALENIHLTVLHLTVTSSESSVLYSFNLKIEEECELSSADDIAGAVYQLFCYM
>gene_prefix09428.mRNA1
MGSTGFQQKVTNDEEACMFALQLVSASILPMTLKAALELDLLEIIAKSGAGAYLSPEEISGQLPTKNPDAPTMLDRILRLLASYDVVSCKLVNGPDGEIRRTYGLAPVCKFLVKNEDGVAMSALALMNQDKVLMESWYYLKDAVLEGGIPFNKAYGMTAFDYHGTDPRFNKIFNNGMSNHSTIIMKKILETYTGFQGLTSIVDESTLIFLMLLKCSFLSWC
>gene_prefix15133.mRNA1
MSGRPESPNSMNHQAEDTSSARLAIMELANMISVPMSLNAIVHLNVPNLMFQSGSNTPLSAQEIAGLIPVSPPADPSNLGRLLRMLTSYGVFTEQIIGSDRKYSLTDIGKTLVDDSNGFSFGPYVLQHHQDALLRSWPLLQSAVLDSSTEPFSVANGGVSAYDYYGDKPEMNDLMQKAMSGVSIPFIDLMINHYHNGFHGIERLVDVGGSSGYCLKMIMQSNPQIKVGINFDLPEVVAKAPFVSGVIHMGGDMFKSVPSGDAIFMKWILTTWTDEECQLILKNCYNALEKGGKVIVCEPVLPEETDNSRRTRALLEGDIFVMAIYRAKGKERTEDEFRQLGTSVGFSKFRAIYFDHFYTLMEFHK
>gene_prefix09208.mRNA1
MAARIKQRLVSLNFIIRSLHLQLLSSSPESQNHKPFLSRHKQRSDLTMGSLGFQHTVTNDEEACLYAMQLASASILPMTLKAAIELDLLEIMAKEGSGNFLSSVEIAAKLPTTNRDAPTMIDRMLRLLASYRILDCKLVENPNGELQRTYGVTPVCKYLTKNEEGVSMSALLLMNQDKVLMESWYHLKDTVLEGGIPFNRAYGMTAFEYHGTDTRFNKIFNNGMSNHSTITMKKILDTYCGFEGLNSIVDVGGGTGATLNMILAKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPNGDAIFMKWILHDWSDEHCLKVLTNCHKSLPKTGKVIIAESILPDYPTPNASGPFQGDLIMLAHNPGGKERTEREFKSLAEKTGFSGFKVVCCAYETWIIEFNK
>gene_prefix14500.mRNA1
MGSTGFQQKVTNDEEACMFAMQLASASILPMSLKAALELDLLEIIAKSGDGAYLSPAEIAAQLPTKNPDASIMLDRILRLLASYDIVSCKLVNEPDGEIRRTYGLAPVCKFFVKNEDGVAISALVLMNQDKVLMESWYHLKDAVLEGGIPFNKAYGMTAFDYHGTDPRFNKIFNNGMSNHSTIIMKKILETYTGFQYLTSIVDVGGGVGATLNMIVSKYPHIKGINFDLPHVEHVGGDMFVSVPSASAIFMKWILHDWSDEHCLKFLANCWKALPESGKVIIVECVLPVYPENSIAANGVFQLDLIMLAHNPGGKERTEKDFKDLAKRAGFSRFKAVCCVYNTWVMEFYK
MKWILHDWSDEHCLKFLANCWKSLPESGKVIIVECILPVYPENNLAANGVFNVDMIMLAQNPGGKERTEKDYKNLAKKAVVWRRFQENNNLIPRLNPSLEGFLDPIIEDQTTFHPMLQQIQSPFLDEQNIHSFLNLKQSQKSWMKIHKTVPEINNVQALETESCITNTNNPQSPVKSEKEEIGGEMFIPKQQSKRGSPQDRQHKRKRNNRLKSMKNREEVENQRMTHITVERNRRKLMNDHLAALRSLMPPSFVQRGDQASIIGGAINFVKELEQMLQSLQAQKHKQRLKEDNIEHPFHGFFTSPQFSTYSNQSAHKCVAKTRRTDFREQSKLALVDLEVTMAETHVNLKVLLRKNSRQLLRSIIALENIHLTVLHLTVTSSESSVLYSFNLKIEEECELSSADDIAGAVYQLFCYM
>gene_prefix09428.mRNA1
MGSTGFQQKVTNDEEACMFALQLVSASILPMTLKAALELDLLEIIAKSGAGAYLSPEEISGQLPTKNPDAPTMLDRILRLLASYDVVSCKLVNGPDGEIRRTYGLAPVCKFLVKNEDGVAMSALALMNQDKVLMESWYYLKDAVLEGGIPFNKAYGMTAFDYHGTDPRFNKIFNNGMSNHSTIIMKKILETYTGFQGLTSIVDESTLIFLMLLKCSFLSWC
>gene_prefix15133.mRNA1
MSGRPESPNSMNHQAEDTSSARLAIMELANMISVPMSLNAIVHLNVPNLMFQSGSNTPLSAQEIAGLIPVSPPADPSNLGRLLRMLTSYGVFTEQIIGSDRKYSLTDIGKTLVDDSNGFSFGPYVLQHHQDALLRSWPLLQSAVLDSSTEPFSVANGGVSAYDYYGDKPEMNDLMQKAMSGVSIPFIDLMINHYHNGFHGIERLVDVGGSSGYCLKMIMQSNPQIKVGINFDLPEVVAKAPFVSGVIHMGGDMFKSVPSGDAIFMKWILTTWTDEECQLILKNCYNALEKGGKVIVCEPVLPEETDNSRRTRALLEGDIFVMAIYRAKGKERTEDEFRQLGTSVGFSKFRAIYFDHFYTLMEFHK
>gene_prefix09208.mRNA1
MAARIKQRLVSLNFIIRSLHLQLLSSSPESQNHKPFLSRHKQRSDLTMGSLGFQHTVTNDEEACLYAMQLASASILPMTLKAAIELDLLEIMAKEGSGNFLSSVEIAAKLPTTNRDAPTMIDRMLRLLASYRILDCKLVENPNGELQRTYGVTPVCKYLTKNEEGVSMSALLLMNQDKVLMESWYHLKDTVLEGGIPFNRAYGMTAFEYHGTDTRFNKIFNNGMSNHSTITMKKILDTYCGFEGLNSIVDVGGGTGATLNMILAKYPSIKGINFDLPHVIEDAPSYPGVEHVGGDMFVSVPNGDAIFMKWILHDWSDEHCLKVLTNCHKSLPKTGKVIIAESILPDYPTPNASGPFQGDLIMLAHNPGGKERTEREFKSLAEKTGFSGFKVVCCAYETWIIEFNK
>gene_prefix14500.mRNA1
MGSTGFQQKVTNDEEACMFAMQLASASILPMSLKAALELDLLEIIAKSGDGAYLSPAEIAAQLPTKNPDASIMLDRILRLLASYDIVSCKLVNEPDGEIRRTYGLAPVCKFFVKNEDGVAISALVLMNQDKVLMESWYHLKDAVLEGGIPFNKAYGMTAFDYHGTDPRFNKIFNNGMSNHSTIIMKKILETYTGFQYLTSIVDVGGGVGATLNMIVSKYPHIKGINFDLPHVEHVGGDMFVSVPSASAIFMKWILHDWSDEHCLKFLANCWKALPESGKVIIVECVLPVYPENSIAANGVFQLDLIMLAHNPGGKERTEKDFKDLAKRAGFSRFKAVCCVYNTWVMEFYK
Gene tree
Gene tree
Sheng jun & Dong yang Teams, Yunnan agriculture University